IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 11.442
AS - Asia 5.045
EU - Europa 3.858
SA - Sud America 1.204
AF - Africa 167
OC - Oceania 27
Continente sconosciuto - Info sul continente non disponibili 6
Totale 21.749
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Nazione #
US - Stati Uniti d'America 11.263
SG - Singapore 2.155
CN - Cina 1.316
BR - Brasile 1.034
IT - Italia 865
HK - Hong Kong 715
SE - Svezia 713
RU - Federazione Russa 514
DE - Germania 484
UA - Ucraina 424
VN - Vietnam 280
GB - Regno Unito 255
FI - Finlandia 253
ID - Indonesia 111
IN - India 109
CA - Canada 97
FR - Francia 73
AR - Argentina 72
JP - Giappone 71
CI - Costa d'Avorio 63
MX - Messico 56
BD - Bangladesh 51
BE - Belgio 46
NL - Olanda 42
ZA - Sudafrica 40
PL - Polonia 39
TR - Turchia 35
IE - Irlanda 31
IQ - Iraq 31
ES - Italia 28
IR - Iran 28
AU - Australia 25
EC - Ecuador 25
UZ - Uzbekistan 21
CL - Cile 18
CH - Svizzera 17
AT - Austria 16
CZ - Repubblica Ceca 16
PK - Pakistan 16
CO - Colombia 15
EG - Egitto 15
MA - Marocco 15
VE - Venezuela 13
IL - Israele 11
KR - Corea 11
UY - Uruguay 11
LT - Lituania 9
SA - Arabia Saudita 9
AZ - Azerbaigian 8
TW - Taiwan 8
AE - Emirati Arabi Uniti 7
NP - Nepal 7
PE - Perù 7
PY - Paraguay 7
TN - Tunisia 7
KE - Kenya 6
LB - Libano 6
OM - Oman 6
DZ - Algeria 5
EE - Estonia 5
GT - Guatemala 5
HU - Ungheria 5
MY - Malesia 5
PH - Filippine 5
BG - Bulgaria 4
DO - Repubblica Dominicana 4
EU - Europa 4
GE - Georgia 4
KZ - Kazakistan 4
TT - Trinidad e Tobago 4
AL - Albania 3
JM - Giamaica 3
JO - Giordania 3
PS - Palestinian Territory 3
TZ - Tanzania 3
AM - Armenia 2
BO - Bolivia 2
BW - Botswana 2
CR - Costa Rica 2
GA - Gabon 2
GI - Gibilterra 2
HN - Honduras 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BJ - Benin 1
BS - Bahamas 1
BY - Bielorussia 1
CG - Congo 1
DK - Danimarca 1
DM - Dominica 1
ET - Etiopia 1
KG - Kirghizistan 1
Totale 21.734
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Città #
Singapore 1.061
Chandler 1.029
Fairfield 1.029
Ashburn 1.005
Jacksonville 936
Woodbridge 895
Hong Kong 712
Houston 612
Nyköping 504
Ann Arbor 442
Cambridge 441
Dallas 441
Seattle 418
Wilmington 360
Beijing 353
Bari 234
Nanjing 218
Roxbury 218
Lawrence 217
New York 181
Los Angeles 162
Boardman 139
Des Moines 136
Princeton 114
Dearborn 94
São Paulo 94
Ho Chi Minh City 90
Brooklyn 81
Sannicandro di Bari 81
Inglewood 72
Santa Clara 70
Nanchang 69
Abidjan 63
Munich 57
Jiaxing 56
Shenyang 53
Tokyo 51
San Diego 50
Hanoi 49
Moscow 47
Brussels 46
Milan 44
Changsha 42
Dong Ket 41
Hebei 41
Buffalo 38
Helsinki 38
Rio de Janeiro 38
London 37
Tianjin 37
San Francisco 36
Jakarta 34
Council Bluffs 33
Montreal 32
Chicago 31
Frankfurt am Main 31
Warsaw 31
Nuremberg 27
Belo Horizonte 26
Denver 26
Dublin 26
Pune 26
Stockholm 26
Toronto 26
Rome 25
Shanghai 24
Johannesburg 22
Chennai 21
Paris 21
Tashkent 21
Boston 19
Florence 19
Guangzhou 19
Poplar 19
San Jose 19
Jinan 18
Mexico City 18
Atlanta 17
Augusta 17
Bitonto 17
Amsterdam 16
Columbus 16
Mumbai 16
Orem 16
Phoenix 16
Porto Alegre 16
San Mateo 16
The Dalles 16
Hefei 15
Washington 15
Brno 14
Manchester 14
Norwalk 14
Adelfia 13
Brasília 13
Falkenstein 13
Turin 13
Turku 13
Wuhan 13
Zhengzhou 13
Totale 14.354
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Nome #
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 215
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 211
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 207
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 195
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 193
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 167
COX-1 Inhibitors: Beyond Structure Toward Therapy 164
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 163
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 161
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 160
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 159
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 158
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 157
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 154
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 154
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 152
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 149
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 148
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 147
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 147
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 144
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 144
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 144
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 140
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 138
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 138
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 135
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 135
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 134
Current and emerging applications of fluorine in medicinal chemistry 134
Update on SAR studies toward new COX-1 selective inhibitors 133
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 133
A chemoenzymatic synthesis of (+)-castanospermine 131
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 131
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 130
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 130
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 129
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 129
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 129
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 126
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 126
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 123
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 122
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 122
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 121
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 120
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 119
A chemoenzymic route to (-)-pyrenophorin 119
A chemoenzymic route to both enantiomers of betaxolol 117
Beta 3-adrenoceptor ligand development history through patent review 117
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 116
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 115
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 115
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 114
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 112
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 111
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 110
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 110
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 110
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 109
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 108
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 108
Reaction of 3-phenylisoxazole with alkyllithiums 108
Isoxazole derivatives and their use as cyclooxygenase inhibitors 107
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 107
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 106
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 106
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 105
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 104
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
Selective COX-1 inhibition: a therapeutic target to be reconsidered 103
Stereospecific synthesis and absolute configuration of Mexiletine 102
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 102
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 100
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 100
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 100
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalyst for ketones reduction 99
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 98
Five-member-ring heterocycles by reacting enolates with dipoles 95
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 95
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 94
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl)benzamidines by reaction of halobenzonitriles with lithium amides 93
C-Alkylation and Michael Addition Involving the Polymer - Supported Carbanion from Methyl Nitroacetate 92
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 92
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 92
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 92
An efficient C2-homologation of aromatic aldehydes via 5-hydroxyisoxazolidines 92
Biocatalytic resolution of (+/-)-hydroxyalkanoic esters. A strategy for enhancing the enantiomeric specificity of lipase-catalyzed ester hydrolysis 92
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 91
Diastereo- and enantio-selective bioreduction of ethyl 2-(4-chlorophenoxy)-3-oxobutanoate clofibrate analogues by Kluyveromyces marxianus and other whole cell biocatalysts 91
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 91
Regiocontrol by anchimeric coordination in the reactions of organocopper reagents with allylic substrates bearing two leaving groups. Synthesis of optically active homoallylic alcohols 90
Myogenic effect of SP-1f and SP-1h two novel 3-adrenoceptor (3-AR) agonists in human colonic circular smooth muscle 90
Chelation-controlled chemo-, regio- and enantio-selective synthesis of homoallylic alcohols 89
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 88
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 88
Decomposition of aryl azides by THF-butyllithium. II. Isolation of 1-aryl-4,5-dihydro-5-hydroxy-1H-1,2,3-triazoles 88
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 88
Potent and stereoselective use-dependent block muscle Na+ channels by a new proline-like tocainide derivative 87
A highly efficient kinetic resolution of w-trimethylsilyl polyunsaturated secondary alcohols by lipase-catalyzed transesterification 87
Totale 12.240
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Categoria #
all - tutte 92.540
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.540
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.160 0 0 0 0 0 65 153 87 220 291 207 137
2021/20221.614 71 251 27 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20264.884 1.191 411 826 1.042 996 418 0 0 0 0 0 0
Totale 22.297