IRIS
SCILIMATI, Antonio
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 15.861
AS - Asia 6.208
EU - Europa 5.767
SA - Sud America 1.550
Continente sconosciuto - Info sul continente non disponibili 605
AF - Africa 263
OC - Oceania 40
Totale 30.294
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 15.348
SG - Singapore 2.481
IT - Italia 2.205
CN - Cina 1.497
BR - Brasile 1.201
HK - Hong Kong 777
SE - Svezia 718
DE - Germania 547
RU - Federazione Russa 528
UA - Ucraina 427
VN - Vietnam 345
FI - Finlandia 327
GB - Regno Unito 316
FR - Francia 312
CA - Canada 243
IN - India 200
BD - Bangladesh 182
ID - Indonesia 133
AR - Argentina 121
TR - Turchia 86
JP - Giappone 78
MX - Messico 77
CI - Costa d'Avorio 64
NL - Olanda 64
IQ - Iraq 62
ZA - Sudafrica 61
CO - Colombia 56
EC - Ecuador 54
BE - Belgio 51
PK - Pakistan 46
PL - Polonia 45
ES - Italia 43
IE - Irlanda 42
UZ - Uzbekistan 39
AU - Australia 37
PH - Filippine 37
SA - Arabia Saudita 36
CL - Cile 35
VE - Venezuela 34
CR - Costa Rica 33
CH - Svizzera 30
IR - Iran 29
MA - Marocco 27
EG - Egitto 23
MY - Malesia 22
SV - El Salvador 22
KR - Corea 21
HN - Honduras 20
KE - Kenya 19
NI - Nicaragua 18
TT - Trinidad e Tobago 18
GT - Guatemala 17
UY - Uruguay 17
AT - Austria 16
CZ - Repubblica Ceca 16
JM - Giamaica 16
PY - Paraguay 16
CW - ???statistics.table.value.countryCode.CW??? 15
LT - Lituania 15
AE - Emirati Arabi Uniti 14
AZ - Azerbaigian 14
IL - Israele 14
TN - Tunisia 13
GP - Guadalupe 12
NP - Nepal 12
TW - Taiwan 12
LB - Libano 11
DO - Repubblica Dominicana 9
DZ - Algeria 9
KZ - Kazakistan 9
OM - Oman 9
PR - Porto Rico 9
SN - Senegal 9
TH - Thailandia 9
JO - Giordania 8
PE - Perù 8
BO - Bolivia 7
EE - Estonia 7
ET - Etiopia 7
NO - Norvegia 7
BG - Bulgaria 6
HU - Ungheria 6
PT - Portogallo 6
PS - Palestinian Territory 5
BB - Barbados 4
EU - Europa 4
GA - Gabon 4
GE - Georgia 4
GR - Grecia 4
MD - Moldavia 4
AG - Antigua e Barbuda 3
AL - Albania 3
BS - Bahamas 3
MK - Macedonia 3
PA - Panama 3
RS - Serbia 3
SC - Seychelles 3
SK - Slovacchia (Repubblica Slovacca) 3
TZ - Tanzania 3
XK - ???statistics.table.value.countryCode.XK??? 3
Totale 29.651
Salva come PNG Salva come JPEG
Città #
Ashburn 1.552
Singapore 1.264
San Jose 1.232
Chandler 1.029
Fairfield 1.029
Jacksonville 940
Woodbridge 896
Hong Kong 767
Milan 631
Houston 615
Nyköping 504
Dallas 477
Cambridge 447
Ann Arbor 442
Seattle 422
Council Bluffs 410
Beijing 383
Wilmington 361
Bari 284
New York 247
Nanjing 219
Roxbury 218
Lawrence 217
Rome 216
Lauterbourg 213
Los Angeles 208
Boardman 164
Santa Clara 152
Des Moines 137
Columbus 133
São Paulo 129
Princeton 117
Washington 115
Helsinki 111
Ho Chi Minh City 104
Dearborn 94
Brooklyn 88
Sannicandro di Bari 81
Inglewood 72
Nanchang 71
Chicago 65
Abidjan 64
Hanoi 59
Munich 58
Tokyo 58
Jiaxing 56
Turin 56
Frankfurt am Main 55
Buffalo 54
Shenyang 53
Toronto 52
San Diego 51
Brussels 49
Figino 49
London 47
Moscow 47
Montreal 46
San Francisco 46
Atlanta 43
Changsha 42
Rio de Janeiro 42
Dong Ket 41
Hebei 41
Tashkent 38
Jakarta 37
Phoenix 37
Tianjin 37
Vancouver 37
Denver 36
Falkenstein 33
Florence 33
Warsaw 33
Dublin 31
Johannesburg 31
Chennai 30
Mexico City 30
Naples 30
Pune 30
North Bergen 29
Nuremberg 29
Belo Horizonte 28
Shanghai 28
Stockholm 27
Orem 24
San José 24
Baghdad 23
Dhaka 23
Paris 23
Medellín 22
Taranto 21
Amsterdam 20
Bologna 20
Boston 20
Istanbul 20
San Salvador 20
Santiago 20
Guangzhou 19
Manchester 19
Mumbai 19
Nairobi 19
Totale 18.965
Salva come PNG Salva come JPEG
Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 271
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 261
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 237
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 228
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 222
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 212
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 207
COX-1 Inhibitors: Beyond Structure Toward Therapy 205
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 195
Novel hClpP protease activators with potential anticancer activity in DIPG patients 193
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 193
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 192
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 189
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 187
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 186
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 185
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 185
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 184
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 181
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 178
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 178
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 177
Effects of Oral Supplementation with Myo-Inositol and D-Chiro-Inositol on Ovarian Functions in Female Long-Term Survivors of Lymphoma: Results from a Prospective Case-Control Analysis 173
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 173
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 173
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 171
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 170
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 167
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 167
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 167
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 167
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 165
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 164
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 164
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 163
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 161
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 161
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 160
Current and emerging applications of fluorine in medicinal chemistry 158
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 157
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 157
A chemoenzymatic synthesis of (+)-castanospermine 156
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 156
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 155
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 155
A chemoenzymic route to (-)-pyrenophorin 155
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 155
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 150
A chemoenzymic route to both enantiomers of betaxolol 149
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 149
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 149
Update on SAR studies toward new COX-1 selective inhibitors 148
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 144
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 144
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 144
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 143
Beta 3-adrenoceptor ligand development history through patent review 140
Isoxazole derivatives and their use as cyclooxygenase inhibitors 139
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 139
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 137
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 137
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 137
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 136
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 135
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 135
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 134
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 134
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 134
A new synthesis of b-phenylamino thioesters and beta-lactams via base-induced ring-opening of 2-phenyl-3-aryl-5-phenylthioisoxazolidines 132
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 132
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects 131
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 131
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 130
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 129
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 129
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 129
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 128
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 128
Reaction of 3-phenylisoxazole with alkyllithiums 128
Translational Theragnosis of Ovarian Cancer: where do we stand? 128
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 127
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 127
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 126
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 126
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 126
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 126
Three-dimensional structure of human cyclooxygenase (hCOX)-1 125
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 125
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 125
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 125
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 125
Selective COX-1 inhibition: a therapeutic target to be reconsidered 124
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 124
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 124
Three-dimensional structure of human cyclooxygenase (hCOX)-1 123
Stereospecific synthesis and absolute configuration of Mexiletine 121
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 121
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 119
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 119
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 117
Totale 15.503
Salva come PNG Salva come JPEG
Categoria #
all - tutte 118.090
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 118.090
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.265 0 0 0 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20269.686 1.191 411 826 1.042 990 502 1.127 323 901 875 416 1.082
2026/20273.195 477 501 968 1.249 0 0 0 0 0 0 0 0
Totale 30.294