IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 13.109
AS - Asia 6.097
EU - Europa 4.534
SA - Sud America 1.478
AF - Africa 257
OC - Oceania 40
Continente sconosciuto - Info sul continente non disponibili 6
Totale 25.521
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Nazione #
US - Stati Uniti d'America 12.865
SG - Singapore 2.466
CN - Cina 1.485
BR - Brasile 1.158
IT - Italia 1.071
HK - Hong Kong 769
SE - Svezia 717
DE - Germania 535
RU - Federazione Russa 526
UA - Ucraina 425
VN - Vietnam 342
FI - Finlandia 327
FR - Francia 297
GB - Regno Unito 284
IN - India 197
ID - Indonesia 130
BD - Bangladesh 129
CA - Canada 125
AR - Argentina 112
TR - Turchia 85
JP - Giappone 78
MX - Messico 74
CI - Costa d'Avorio 64
IQ - Iraq 62
NL - Olanda 62
ZA - Sudafrica 61
BE - Belgio 49
EC - Ecuador 48
CO - Colombia 47
PK - Pakistan 45
PL - Polonia 43
UZ - Uzbekistan 39
ES - Italia 38
IE - Irlanda 38
AU - Australia 37
PH - Filippine 37
CL - Cile 33
SA - Arabia Saudita 33
VE - Venezuela 31
IR - Iran 29
MA - Marocco 27
EG - Egitto 23
CH - Svizzera 20
KR - Corea 20
MY - Malesia 19
KE - Kenya 17
UY - Uruguay 17
AT - Austria 16
CZ - Repubblica Ceca 16
PY - Paraguay 16
AZ - Azerbaigian 14
IL - Israele 14
LT - Lituania 13
TN - Tunisia 13
AE - Emirati Arabi Uniti 12
NP - Nepal 12
TW - Taiwan 12
LB - Libano 11
DZ - Algeria 9
KZ - Kazakistan 9
OM - Oman 9
SN - Senegal 9
JM - Giamaica 8
JO - Giordania 8
PE - Perù 8
BO - Bolivia 7
DO - Repubblica Dominicana 7
ET - Etiopia 7
GT - Guatemala 7
NO - Norvegia 7
HU - Ungheria 6
PT - Portogallo 6
TH - Thailandia 6
BG - Bulgaria 5
CR - Costa Rica 5
EE - Estonia 5
PS - Palestinian Territory 5
EU - Europa 4
GA - Gabon 4
GE - Georgia 4
MD - Moldavia 4
TT - Trinidad e Tobago 4
AL - Albania 3
HN - Honduras 3
PA - Panama 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
TZ - Tanzania 3
AM - Armenia 2
BB - Barbados 2
BJ - Benin 2
BW - Botswana 2
BY - Bielorussia 2
CY - Cipro 2
GI - Gibilterra 2
GR - Grecia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
RO - Romania 2
Totale 25.480
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Città #
Singapore 1.259
Ashburn 1.188
Chandler 1.029
Fairfield 1.029
Jacksonville 939
Woodbridge 895
San Jose 851
Hong Kong 760
Houston 614
Nyköping 504
Dallas 452
Cambridge 445
Ann Arbor 442
Seattle 418
Beijing 377
Wilmington 360
Bari 259
Nanjing 219
Roxbury 218
Lawrence 217
Lauterbourg 213
New York 211
Los Angeles 176
Boardman 161
Des Moines 137
Princeton 114
Helsinki 111
Ho Chi Minh City 103
São Paulo 99
Santa Clara 97
Dearborn 94
Brooklyn 82
Council Bluffs 81
Sannicandro di Bari 81
Inglewood 72
Nanchang 71
Abidjan 64
Hanoi 58
Tokyo 58
Munich 57
Jiaxing 56
Shenyang 53
Frankfurt am Main 52
San Diego 51
Milan 50
Brussels 48
Buffalo 48
Moscow 47
London 43
Changsha 42
Rio de Janeiro 42
Rome 42
Dong Ket 41
Hebei 41
Chicago 40
San Francisco 40
Tashkent 38
Jakarta 37
Montreal 37
Tianjin 37
Falkenstein 33
Warsaw 33
Denver 31
Dublin 31
Johannesburg 31
Pune 30
Chennai 29
Mexico City 29
Nuremberg 29
Atlanta 28
Belo Horizonte 28
Toronto 28
Shanghai 27
Stockholm 26
Orem 24
Baghdad 23
Dhaka 22
Paris 22
Phoenix 22
Boston 20
Amsterdam 19
Florence 19
Guangzhou 19
Istanbul 19
Medellín 19
Mumbai 19
Poplar 19
Santiago 19
Columbus 18
Jinan 18
Manchester 18
Porto Alegre 18
The Dalles 18
Augusta 17
Bitonto 17
Jeddah 17
Nairobi 17
Washington 17
Buenos Aires 16
San Mateo 16
Totale 16.405
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Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 241
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 234
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 227
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 211
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 208
COX-1 Inhibitors: Beyond Structure Toward Therapy 183
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 182
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 180
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 179
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 178
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 177
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 174
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 174
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 172
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 170
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 167
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 167
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 161
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 161
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 159
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 159
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 159
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 157
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 153
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 152
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 152
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 151
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 151
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 150
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 149
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 149
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 149
Current and emerging applications of fluorine in medicinal chemistry 148
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 148
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 146
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 145
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 145
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 143
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 142
Update on SAR studies toward new COX-1 selective inhibitors 141
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 141
A chemoenzymatic synthesis of (+)-castanospermine 140
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 137
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 136
A chemoenzymic route to (-)-pyrenophorin 134
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 131
A chemoenzymic route to both enantiomers of betaxolol 131
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 131
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 131
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 130
Beta 3-adrenoceptor ligand development history through patent review 129
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 128
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 128
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 127
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 127
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 124
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 124
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 123
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 123
Isoxazole derivatives and their use as cyclooxygenase inhibitors 122
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 122
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 121
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 120
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 119
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 119
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 119
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 118
Reaction of 3-phenylisoxazole with alkyllithiums 118
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 118
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 117
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 116
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 115
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 115
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 114
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 114
A new synthesis of b-phenylamino thioesters and beta-lactams via base-induced ring-opening of 2-phenyl-3-aryl-5-phenylthioisoxazolidines 114
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 113
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 112
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 111
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 110
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 110
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 109
Selective COX-1 inhibition: a therapeutic target to be reconsidered 109
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 108
Stereospecific synthesis and absolute configuration of Mexiletine 108
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 108
Translational Theragnosis of Ovarian Cancer: where do we stand? 108
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 108
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects 107
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 107
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 107
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 107
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 106
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 106
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 105
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalyst for ketones reduction 105
Myogenic effect of SP-1f and SP-1h two novel 3-adrenoceptor (3-AR) agonists in human colonic circular smooth muscle 103
Five-member-ring heterocycles by reacting enolates with dipoles 102
Effects of Oral Supplementation with Myo-Inositol and D-Chiro-Inositol on Ovarian Functions in Female Long-Term Survivors of Lymphoma: Results from a Prospective Case-Control Analysis 101
Biocatalytic resolution of (+/-)-hydroxyalkanoic esters. A strategy for enhancing the enantiomeric specificity of lipase-catalyzed ester hydrolysis 101
Totale 13.741
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Categoria #
all - tutte 103.759
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 103.759
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021137 0 0 0 0 0 0 0 0 0 0 0 137
2021/20221.614 71 251 27 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20268.680 1.191 411 826 1.042 990 502 1.127 323 901 875 416 76
Totale 26.093