IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 14.321
AS - Asia 6.198
EU - Europa 5.596
SA - Sud America 1.516
Continente sconosciuto - Info sul continente non disponibili 587
AF - Africa 263
OC - Oceania 40
Totale 28.521
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Nazione #
US - Stati Uniti d'America 14.007
SG - Singapore 2.478
IT - Italia 2.089
CN - Cina 1.497
BR - Brasile 1.169
HK - Hong Kong 776
SE - Svezia 718
DE - Germania 540
RU - Federazione Russa 526
UA - Ucraina 426
VN - Vietnam 345
FI - Finlandia 327
FR - Francia 309
GB - Regno Unito 288
IN - India 199
BD - Bangladesh 179
CA - Canada 170
ID - Indonesia 133
AR - Argentina 121
TR - Turchia 86
JP - Giappone 78
MX - Messico 76
CI - Costa d'Avorio 64
NL - Olanda 64
IQ - Iraq 62
ZA - Sudafrica 61
CO - Colombia 55
EC - Ecuador 54
BE - Belgio 50
PK - Pakistan 46
PL - Polonia 45
ES - Italia 41
UZ - Uzbekistan 39
IE - Irlanda 38
AU - Australia 37
PH - Filippine 37
SA - Arabia Saudita 36
CL - Cile 35
VE - Venezuela 33
CH - Svizzera 30
IR - Iran 29
MA - Marocco 27
EG - Egitto 23
KR - Corea 21
MY - Malesia 21
KE - Kenya 19
UY - Uruguay 17
AT - Austria 16
CZ - Repubblica Ceca 16
PY - Paraguay 16
AE - Emirati Arabi Uniti 14
AZ - Azerbaigian 14
IL - Israele 14
JM - Giamaica 14
LT - Lituania 13
TN - Tunisia 13
NP - Nepal 12
TW - Taiwan 12
LB - Libano 11
CR - Costa Rica 9
DZ - Algeria 9
GT - Guatemala 9
KZ - Kazakistan 9
OM - Oman 9
SN - Senegal 9
HN - Honduras 8
JO - Giordania 8
PE - Perù 8
TH - Thailandia 8
BO - Bolivia 7
DO - Repubblica Dominicana 7
ET - Etiopia 7
NO - Norvegia 7
BG - Bulgaria 6
HU - Ungheria 6
PT - Portogallo 6
EE - Estonia 5
PS - Palestinian Territory 5
TT - Trinidad e Tobago 5
EU - Europa 4
GA - Gabon 4
GE - Georgia 4
MD - Moldavia 4
AL - Albania 3
MK - Macedonia 3
PA - Panama 3
RS - Serbia 3
SC - Seychelles 3
SK - Slovacchia (Repubblica Slovacca) 3
SV - El Salvador 3
TZ - Tanzania 3
XK - ???statistics.table.value.countryCode.XK??? 3
AM - Armenia 2
BB - Barbados 2
BJ - Benin 2
BS - Bahamas 2
BW - Botswana 2
BY - Bielorussia 2
CY - Cipro 2
GI - Gibilterra 2
Totale 27.892
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Città #
Singapore 1.264
Ashburn 1.230
San Jose 1.086
Chandler 1.029
Fairfield 1.029
Jacksonville 940
Woodbridge 896
Hong Kong 766
Milan 620
Houston 614
Nyköping 504
Dallas 468
Cambridge 445
Ann Arbor 442
Seattle 420
Beijing 383
Council Bluffs 362
Wilmington 360
Bari 266
New York 225
Nanjing 219
Roxbury 218
Lawrence 217
Lauterbourg 213
Rome 204
Los Angeles 193
Boardman 162
Des Moines 137
Santa Clara 134
Columbus 132
Princeton 116
Helsinki 111
Ho Chi Minh City 104
São Paulo 101
Dearborn 94
Brooklyn 83
Sannicandro di Bari 81
Inglewood 72
Nanchang 71
Abidjan 64
Chicago 59
Hanoi 59
Tokyo 58
Munich 57
Jiaxing 56
Buffalo 54
Frankfurt am Main 54
Turin 54
Shenyang 53
San Diego 51
Figino 49
Brussels 48
Moscow 47
London 45
San Francisco 43
Changsha 42
Rio de Janeiro 42
Dong Ket 41
Hebei 41
Montreal 38
Tashkent 38
Jakarta 37
Tianjin 37
Denver 35
Atlanta 34
Falkenstein 33
Toronto 33
Warsaw 33
Phoenix 32
Dublin 31
Johannesburg 31
Chennai 30
Mexico City 30
Pune 30
Vancouver 30
Nuremberg 29
Belo Horizonte 28
Shanghai 28
Stockholm 27
Florence 26
Orem 24
Baghdad 23
Paris 23
Dhaka 22
Naples 22
Medellín 21
Taranto 21
Amsterdam 20
Boston 20
Istanbul 20
Santiago 20
Guangzhou 19
Manchester 19
Mumbai 19
Nairobi 19
Poplar 19
Washington 19
Bitonto 18
Jeddah 18
Jinan 18
Totale 18.102
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Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 261
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 242
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 234
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 220
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 217
COX-1 Inhibitors: Beyond Structure Toward Therapy 199
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 193
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 188
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 187
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 186
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 186
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 181
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 179
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 178
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 178
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 177
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 175
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 175
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 173
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 172
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 168
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 165
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 164
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 164
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 163
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 162
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 161
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 160
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 159
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 159
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 156
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 156
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 155
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 155
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 155
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 154
Current and emerging applications of fluorine in medicinal chemistry 154
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 152
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 152
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 151
A chemoenzymic route to (-)-pyrenophorin 148
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 147
A chemoenzymatic synthesis of (+)-castanospermine 145
Update on SAR studies toward new COX-1 selective inhibitors 144
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 144
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 143
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 143
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 143
A chemoenzymic route to both enantiomers of betaxolol 142
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 140
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 139
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 138
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 137
Beta 3-adrenoceptor ligand development history through patent review 136
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 135
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 134
Isoxazole derivatives and their use as cyclooxygenase inhibitors 133
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 132
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 132
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 130
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 130
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 129
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 128
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 128
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 127
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 126
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 126
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 125
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 125
Reaction of 3-phenylisoxazole with alkyllithiums 125
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 125
A new synthesis of b-phenylamino thioesters and beta-lactams via base-induced ring-opening of 2-phenyl-3-aryl-5-phenylthioisoxazolidines 125
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 123
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 122
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 122
Three-dimensional structure of human cyclooxygenase (hCOX)-1 121
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 121
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 121
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects 120
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 120
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 120
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 120
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 120
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 120
Selective COX-1 inhibition: a therapeutic target to be reconsidered 119
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 119
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 118
Translational Theragnosis of Ovarian Cancer: where do we stand? 118
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 116
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 115
Effects of Oral Supplementation with Myo-Inositol and D-Chiro-Inositol on Ovarian Functions in Female Long-Term Survivors of Lymphoma: Results from a Prospective Case-Control Analysis 114
Stereospecific synthesis and absolute configuration of Mexiletine 114
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 114
Three-dimensional structure of human cyclooxygenase (hCOX)-1 114
Novel hClpP protease activators with potential anticancer activity in DIPG patients 113
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 113
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 113
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 113
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 112
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 112
Totale 14.657
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Categoria #
all - tutte 112.315
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 112.315
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.292 0 0 27 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20269.686 1.191 411 826 1.042 990 502 1.127 323 901 875 416 1.082
2026/20271.422 477 501 444 0 0 0 0 0 0 0 0 0
Totale 28.521