IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 12.700
AS - Asia 6.006
EU - Europa 4.443
SA - Sud America 1.475
AF - Africa 257
OC - Oceania 40
Continente sconosciuto - Info sul continente non disponibili 6
Totale 24.927
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Nazione #
US - Stati Uniti d'America 12.484
SG - Singapore 2.441
CN - Cina 1.459
BR - Brasile 1.155
IT - Italia 995
HK - Hong Kong 758
SE - Svezia 717
DE - Germania 535
RU - Federazione Russa 526
UA - Ucraina 425
VN - Vietnam 341
FI - Finlandia 327
FR - Francia 297
GB - Regno Unito 281
IN - India 197
ID - Indonesia 130
AR - Argentina 112
CA - Canada 108
BD - Bangladesh 105
TR - Turchia 85
JP - Giappone 76
MX - Messico 69
CI - Costa d'Avorio 64
IQ - Iraq 62
NL - Olanda 61
ZA - Sudafrica 61
BE - Belgio 49
EC - Ecuador 48
CO - Colombia 47
PK - Pakistan 44
PL - Polonia 43
UZ - Uzbekistan 39
IE - Irlanda 38
AU - Australia 37
PH - Filippine 37
CL - Cile 33
ES - Italia 33
SA - Arabia Saudita 32
VE - Venezuela 31
IR - Iran 29
MA - Marocco 27
EG - Egitto 23
KR - Corea 20
MY - Malesia 19
CH - Svizzera 17
KE - Kenya 17
UY - Uruguay 17
AT - Austria 16
CZ - Repubblica Ceca 16
PY - Paraguay 16
AZ - Azerbaigian 14
IL - Israele 14
LT - Lituania 13
TN - Tunisia 13
AE - Emirati Arabi Uniti 12
NP - Nepal 12
TW - Taiwan 12
LB - Libano 11
DZ - Algeria 9
KZ - Kazakistan 9
OM - Oman 9
SN - Senegal 9
JO - Giordania 8
PE - Perù 8
BO - Bolivia 7
DO - Repubblica Dominicana 7
ET - Etiopia 7
JM - Giamaica 7
NO - Norvegia 7
HU - Ungheria 6
TH - Thailandia 6
BG - Bulgaria 5
EE - Estonia 5
GT - Guatemala 5
PS - Palestinian Territory 5
EU - Europa 4
GA - Gabon 4
GE - Georgia 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
AL - Albania 3
CR - Costa Rica 3
HN - Honduras 3
MD - Moldavia 3
PA - Panama 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
TZ - Tanzania 3
AM - Armenia 2
BJ - Benin 2
BW - Botswana 2
BY - Bielorussia 2
CY - Cipro 2
GI - Gibilterra 2
GR - Grecia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
RO - Romania 2
SI - Slovenia 2
Totale 24.887
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Città #
Singapore 1.247
Ashburn 1.163
Chandler 1.029
Fairfield 1.029
Jacksonville 937
Woodbridge 895
Hong Kong 749
San Jose 731
Houston 614
Nyköping 504
Cambridge 445
Dallas 445
Ann Arbor 442
Seattle 418
Beijing 368
Wilmington 360
Bari 247
Nanjing 219
Roxbury 218
Lawrence 217
Lauterbourg 213
New York 193
Los Angeles 169
Boardman 140
Des Moines 137
Princeton 114
Helsinki 111
Ho Chi Minh City 102
São Paulo 99
Dearborn 94
Santa Clara 87
Brooklyn 81
Sannicandro di Bari 81
Council Bluffs 77
Inglewood 72
Nanchang 71
Abidjan 64
Hanoi 58
Munich 57
Jiaxing 56
Tokyo 56
Shenyang 53
Frankfurt am Main 52
San Diego 50
Brussels 48
Milan 47
Moscow 47
Buffalo 43
Changsha 42
London 42
Rio de Janeiro 42
Dong Ket 41
Hebei 41
Chicago 38
San Francisco 38
Tashkent 38
Jakarta 37
Tianjin 37
Rome 34
Falkenstein 33
Warsaw 33
Montreal 32
Dublin 31
Johannesburg 31
Pune 30
Chennai 29
Nuremberg 29
Denver 28
Belo Horizonte 27
Shanghai 26
Stockholm 26
Toronto 26
Mexico City 24
Atlanta 23
Baghdad 23
Orem 23
Paris 22
Dhaka 21
Amsterdam 19
Boston 19
Florence 19
Guangzhou 19
Istanbul 19
Medellín 19
Mumbai 19
Phoenix 19
Poplar 19
Santiago 19
Jinan 18
Manchester 18
Porto Alegre 18
The Dalles 18
Augusta 17
Bitonto 17
Columbus 17
Nairobi 17
Buenos Aires 16
Jeddah 16
San Mateo 16
Washington 16
Totale 16.090
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Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 236
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 229
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 224
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 207
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 207
COX-1 Inhibitors: Beyond Structure Toward Therapy 180
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 178
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 178
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 176
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 175
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 175
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 173
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 172
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 170
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 164
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 163
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 163
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 158
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 158
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 157
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 157
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 155
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 153
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 152
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 149
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 149
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 149
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 148
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 147
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 147
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 146
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 145
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 145
Current and emerging applications of fluorine in medicinal chemistry 145
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 144
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 144
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 142
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 141
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 140
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 140
A chemoenzymatic synthesis of (+)-castanospermine 139
Update on SAR studies toward new COX-1 selective inhibitors 137
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 135
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 135
A chemoenzymic route to (-)-pyrenophorin 133
A chemoenzymic route to both enantiomers of betaxolol 129
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 129
Beta 3-adrenoceptor ligand development history through patent review 128
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 128
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 127
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 127
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 127
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 125
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 124
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 123
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 123
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 122
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 122
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 120
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 119
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 119
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 118
Isoxazole derivatives and their use as cyclooxygenase inhibitors 117
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 117
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 117
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 116
Reaction of 3-phenylisoxazole with alkyllithiums 116
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 116
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 116
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 115
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 113
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 113
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 112
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 112
A new synthesis of b-phenylamino thioesters and beta-lactams via base-induced ring-opening of 2-phenyl-3-aryl-5-phenylthioisoxazolidines 112
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 111
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 110
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 110
Selective COX-1 inhibition: a therapeutic target to be reconsidered 109
Stereospecific synthesis and absolute configuration of Mexiletine 108
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 108
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 107
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 107
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 107
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 106
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 106
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 105
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 105
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalyst for ketones reduction 105
Translational Theragnosis of Ovarian Cancer: where do we stand? 105
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 104
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 102
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 102
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 102
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects 101
Biocatalytic resolution of (+/-)-hydroxyalkanoic esters. A strategy for enhancing the enantiomeric specificity of lipase-catalyzed ester hydrolysis 101
Five-member-ring heterocycles by reacting enolates with dipoles 100
C-Alkylation and Michael Addition Involving the Polymer - Supported Carbanion from Methyl Nitroacetate 99
A highly efficient kinetic resolution of w-trimethylsilyl polyunsaturated secondary alcohols by lipase-catalyzed transesterification 99
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 98
Totale 13.479
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Categoria #
all - tutte 99.222
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 99.222
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021635 0 0 0 0 0 0 0 0 0 291 207 137
2021/20221.614 71 251 27 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20268.068 1.191 411 826 1.042 990 502 1.127 323 901 755 0 0
Totale 25.481