IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 9.191
EU - Europa 2.677
AS - Asia 1.179
SA - Sud America 24
OC - Oceania 9
AF - Africa 8
Continente sconosciuto - Info sul continente non disponibili 4
Totale 13.092
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Nazione #
US - Stati Uniti d'America 9.177
CN - Cina 914
SE - Svezia 689
IT - Italia 661
UA - Ucraina 410
DE - Germania 358
FI - Finlandia 220
GB - Regno Unito 147
ID - Indonesia 63
SG - Singapore 55
IN - India 48
VN - Vietnam 44
FR - Francia 42
BE - Belgio 40
RU - Federazione Russa 38
IE - Irlanda 25
IR - Iran 18
CZ - Repubblica Ceca 16
JP - Giappone 16
CL - Cile 15
CA - Canada 13
AU - Australia 7
EG - Egitto 7
KR - Corea 7
PL - Polonia 7
NL - Olanda 5
EU - Europa 4
HU - Ungheria 4
PE - Perù 4
AT - Austria 3
BG - Bulgaria 3
IL - Israele 3
IQ - Iraq 3
TR - Turchia 3
AR - Argentina 2
BR - Brasile 2
ES - Italia 2
NZ - Nuova Zelanda 2
AM - Armenia 1
CH - Svizzera 1
CO - Colombia 1
DK - Danimarca 1
EE - Estonia 1
HK - Hong Kong 1
KH - Cambogia 1
LU - Lussemburgo 1
PA - Panama 1
PK - Pakistan 1
RO - Romania 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
ZA - Sudafrica 1
Totale 13.092
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Città #
Chandler 1.042
Fairfield 1.031
Jacksonville 935
Woodbridge 896
Houston 602
Ashburn 527
Nyköping 505
Ann Arbor 442
Cambridge 442
Seattle 412
Wilmington 359
Lawrence 219
Roxbury 219
Nanjing 218
Bari 206
Beijing 148
Des Moines 137
Boardman 129
New York 127
Princeton 114
Dearborn 94
Sannicandro di Bari 82
Inglewood 72
Nanchang 69
Jiaxing 56
Shenyang 53
Brooklyn 52
San Diego 49
Dong Ket 41
Hebei 41
Los Angeles 41
Brussels 40
Changsha 39
Tianjin 37
Singapore 31
Dublin 24
Pune 24
Milan 22
Paris 21
Helsinki 18
London 18
Shanghai 18
Jinan 17
Augusta 16
San Mateo 16
Washington 15
Brno 14
Guangzhou 14
Hefei 14
Rome 14
Adelfia 13
Bitonto 13
Falls Church 12
Leawood 12
Ningbo 12
Norwalk 12
Wuhan 12
Ardabil 11
Monmouth Junction 11
San Francisco 11
Zhengzhou 11
Redwood City 10
Tokyo 10
Turin 10
Frankfurt am Main 9
Kunming 9
Taizhou 9
Indiana 8
Munich 8
Santiago 8
Taranto 8
Toronto 7
Auburn Hills 6
Bologna 6
Jinhua 6
Kilburn 6
Napoli 6
Chongqing 5
Francavilla Fontana 5
Mumbai 5
Redmond 5
Arequipa 4
Baotou 4
Bremen 4
Brescia 4
Casoria 4
Chicago 4
Florence 4
Hangzhou 4
Kornye 4
Pescara 4
Qingdao 4
Stockholm 4
Ulez 4
Valenzano 4
Valparaiso 4
Wallsend 4
Wuxi 4
Ahmedabad 3
Chengdu 3
Totale 10.122
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Nome #
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 162
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 145
COX-1 Inhibitors: Beyond Structure Toward Therapy 130
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 126
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 125
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 121
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 120
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 119
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 118
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 117
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 116
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 116
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 114
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 109
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 108
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 107
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 106
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 105
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 104
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 103
Update on SAR studies toward new COX-1 selective inhibitors 102
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 100
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 100
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 98
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 98
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 97
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 97
A chemoenzymatic synthesis of (+)-castanospermine 96
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 96
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 95
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 94
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 94
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 94
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 93
Current and emerging applications of fluorine in medicinal chemistry 92
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 91
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 90
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 89
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 88
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 87
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 87
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 87
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 87
Selective COX-1 inhibition: a therapeutic target to be reconsidered 86
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 86
Reaction of 3-phenylisoxazole with alkyllithiums 86
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 86
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 86
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 85
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 85
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 82
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 82
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 81
Stereospecific synthesis and absolute configuration of Mexiletine 79
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 78
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 78
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 77
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 77
Biocatalytic resolution of (+/-)-hydroxyalkanoic esters. A strategy for enhancing the enantiomeric specificity of lipase-catalyzed ester hydrolysis 76
Regiocontrol by anchimeric coordination in the reactions of organocopper reagents with allylic substrates bearing two leaving groups. Synthesis of optically active homoallylic alcohols 75
null 75
Diastereo- and enantio-selective bioreduction of ethyl 2-(4-chlorophenoxy)-3-oxobutanoate clofibrate analogues by Kluyveromyces marxianus and other whole cell biocatalysts 74
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 72
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 72
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 71
Optically active Mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 71
Five-member-ring heterocycles by reacting enolates with dipoles 69
Beta 3-adrenoceptor ligand development history through patent review 69
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 69
An efficient C2-homologation of aromatic aldehydes via 5-hydroxyisoxazolidines 69
Decomposition of aryl azides by THF-butyllithium. II. Isolation of 1-aryl-4,5-dihydro-5-hydroxy-1H-1,2,3-triazoles 69
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 68
Isoxazole derivatives and their use as cyclooxygenase inhibitors 68
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 68
A chemoenzymic route to both enantiomers of betaxolol 67
A chemoenzymic route to (-)-pyrenophorin 66
Chelation-controlled chemo-, regio- and enantio-selective synthesis of homoallylic alcohols 65
Beta-3 receptor ligands and their use in therapy 64
Reaction of caesium 4-chlorophenate and chlorohydrins from threonines: synthesis of clofibrate analogues 63
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalyst for ketones reduction 63
Stereoselective dimerization of 3-arylisoxazoles to cage-shaped bis-β-lactams syn-2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by hindered lithium amides 63
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 63
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 62
Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles 62
Selective reduction of aldehydes to the corresponding primary alcohols by lithium enolate of acetaldehyde 61
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 60
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 60
C-Alkylation and Michael Addition Involving the Polymer - Supported Carbanion from Methyl Nitroacetate 59
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl)benzamidines by reaction of halobenzonitriles with lithium amides 59
Highly selective COX-1 inhibitors as novel cardioprotective anti-thrombotic agents 58
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 58
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 58
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 57
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 57
Ligandi del recettore beta-3 adrenergico e loro uso in terapia 57
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 57
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 57
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 56
Enantioselective bio-reduction of prochiral ketones by the non-conventional yeast Kluyveromyces marxianus 56
An efficient biocatalyzed kinetic resolution of methyl (Z)-3-(arylsulfinyl)propenoates 55
Totale 8.455
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Categoria #
all - tutte 53.932
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.932
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.569 0 205 73 228 319 210 375 230 361 201 305 62
2020/20212.067 297 85 224 85 208 65 153 87 220 297 207 139
2021/20221.620 71 251 27 50 83 108 67 81 104 102 260 416
2022/20232.714 399 255 193 253 373 345 22 301 421 32 66 54
2023/20241.151 70 167 67 71 90 216 56 51 150 65 31 117
2024/2025183 144 39 0 0 0 0 0 0 0 0 0 0
Totale 13.523