IRIS
SCILIMATI, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 11.369
AS - Asia 4.864
EU - Europa 3.820
SA - Sud America 1.195
AF - Africa 160
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 6
Totale 21.440
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Nazione #
US - Stati Uniti d'America 11.195
SG - Singapore 2.087
CN - Cina 1.292
BR - Brasile 1.027
IT - Italia 854
SE - Svezia 712
HK - Hong Kong 687
RU - Federazione Russa 513
DE - Germania 481
UA - Ucraina 424
FI - Finlandia 252
GB - Regno Unito 247
VN - Vietnam 242
ID - Indonesia 111
IN - India 108
CA - Canada 95
FR - Francia 73
AR - Argentina 70
JP - Giappone 67
CI - Costa d'Avorio 63
MX - Messico 53
BD - Bangladesh 47
BE - Belgio 46
NL - Olanda 41
ZA - Sudafrica 37
PL - Polonia 36
TR - Turchia 34
IE - Irlanda 30
IQ - Iraq 30
EC - Ecuador 25
ES - Italia 25
IR - Iran 25
AU - Australia 24
UZ - Uzbekistan 20
CL - Cile 18
CH - Svizzera 16
CZ - Repubblica Ceca 16
PK - Pakistan 16
AT - Austria 15
CO - Colombia 15
EG - Egitto 15
MA - Marocco 14
VE - Venezuela 13
KR - Corea 11
UY - Uruguay 11
IL - Israele 10
SA - Arabia Saudita 8
AZ - Azerbaigian 7
LT - Lituania 7
NP - Nepal 7
PE - Perù 7
PY - Paraguay 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
LB - Libano 6
OM - Oman 6
TW - Taiwan 6
EE - Estonia 5
GT - Guatemala 5
HU - Ungheria 5
KE - Kenya 5
PH - Filippine 5
BG - Bulgaria 4
DO - Repubblica Dominicana 4
DZ - Algeria 4
EU - Europa 4
GE - Georgia 4
KZ - Kazakistan 4
MY - Malesia 4
TT - Trinidad e Tobago 4
JM - Giamaica 3
JO - Giordania 3
PS - Palestinian Territory 3
TZ - Tanzania 3
AL - Albania 2
AM - Armenia 2
BO - Bolivia 2
BW - Botswana 2
CR - Costa Rica 2
GI - Gibilterra 2
HN - Honduras 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BJ - Benin 1
BS - Bahamas 1
BY - Bielorussia 1
CG - Congo 1
DK - Danimarca 1
DM - Dominica 1
ET - Etiopia 1
GA - Gabon 1
KG - Kirghizistan 1
Totale 21.426
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Città #
Chandler 1.029
Fairfield 1.029
Singapore 993
Ashburn 992
Jacksonville 936
Woodbridge 895
Hong Kong 684
Houston 611
Nyköping 504
Ann Arbor 442
Cambridge 441
Dallas 441
Seattle 417
Wilmington 360
Beijing 352
Bari 231
Nanjing 218
Roxbury 218
Lawrence 217
New York 174
Los Angeles 158
Boardman 138
Des Moines 136
Princeton 114
Dearborn 94
São Paulo 91
Sannicandro di Bari 81
Brooklyn 80
Ho Chi Minh City 74
Inglewood 72
Santa Clara 70
Nanchang 69
Abidjan 63
Munich 57
Jiaxing 56
Shenyang 53
San Diego 50
Moscow 47
Tokyo 47
Brussels 46
Hanoi 44
Milan 44
Changsha 42
Dong Ket 41
Hebei 41
Buffalo 38
Rio de Janeiro 38
Helsinki 37
Tianjin 37
San Francisco 36
London 35
Jakarta 34
Council Bluffs 31
Frankfurt am Main 31
Montreal 30
Chicago 29
Warsaw 28
Dublin 26
Pune 26
Toronto 26
Belo Horizonte 25
Nuremberg 25
Rome 25
Stockholm 25
Shanghai 24
Denver 23
Chennai 21
Paris 21
Tashkent 20
Florence 19
Guangzhou 19
Johannesburg 19
Boston 18
Jinan 18
Augusta 17
Bitonto 17
Columbus 16
Mexico City 16
Poplar 16
Porto Alegre 16
San Mateo 16
The Dalles 16
Amsterdam 15
Atlanta 15
Hefei 15
Mumbai 15
Phoenix 15
Washington 15
Brno 14
Norwalk 14
Adelfia 13
Brasília 13
Falkenstein 13
Turin 13
Turku 13
Wuhan 13
Zhengzhou 13
Dhaka 12
Falls Church 12
Leawood 12
Totale 14.151
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Nome #
Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells 213
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 209
A novel injectable formulation of 6-Fluoro-L-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease 204
Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts 193
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 191
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis 165
COX-1 Inhibitors: Beyond Structure Toward Therapy 164
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 162
3-Aryl-5-vinyl-2-isoxazolines and 3-aryl-5-vinylisoxazoles from aryl nitrile oxides and methyl vinyl ketone lithium enolate: Reaction limits and synthetic utility exploitation 159
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 159
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 158
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 157
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 153
PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation 153
[18F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage 153
Zoledronic acid modulation of TRPV1 channel currents in osteoblast cell line and native rat and mouse bone marrow-derived osteoblasts: Cell proliferation and mineralization effect 150
1-Aril-5-idrossi-1,2,3-triazoline precursori di Diazometano 147
Screening yeasts for the stereoselective reduction of oxoester clofibrate analogues 147
General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model 147
The reaction of arylaldehydes with hexamethylphosphorous triamide and the use of the resulting products for the synthesis of enamines and deoxybenzoins 146
Reattività di Nitrilossidi in THF/n-BuLi. Sintesi di 5-Idrossi-Δ2-isossazoline 144
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism 144
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity 140
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 138
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 137
Baker's yeast-mediated reduction of ethyl 2-(4-chlorophenoxy)-3-oxoalkanoates intermediates for potential PPARa ligands 136
Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase‑1 (COX-1) Inhibitors 135
Selective cyclooxygenase-1 inhibition by P6 and gastrotoxicity: Preliminary investigation 134
Current and emerging applications of fluorine in medicinal chemistry 134
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 133
Update on SAR studies toward new COX-1 selective inhibitors 133
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells 131
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines 130
Baker’s yeast-induced asymmetric reduction of a-ketosulfides: synthesis of optically active 1-(benzothiazol-2-ylsulfanyl)-2-alkanols, 2-alkanols, and thiiranes 130
A chemoenzymatic synthesis of (+)-castanospermine 129
Highly Selective Cyclooxygenase-1 Inhibitors P6 and Mofezolac Counteract Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation 129
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 127
Intelligent microarray data analysis through non-negative matrix factorization to study human multiple myeloma cell lines 127
Beta 3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding 125
A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists 125
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 124
Procedimento per la sintesi di alcoli chirali mediante impiego di lactobacillus reuteri 120
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 120
Pharmaceutical development of novel lactate-based 6-fluoro-L-DOPA formulations 120
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles 119
Effect of the aryl group substituent in the dimerization of 3-arylisoxazoles to syn 2,6-diaryl-3,7-diazatricyclo[4.2.0.02,5]octan-4,8-diones induced by LDA 118
A chemoenzymic route to (-)-pyrenophorin 117
Beta 3-adrenoceptor ligand development history through patent review 116
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 116
A chemoenzymic route to both enantiomers of betaxolol 115
A Novel Synthesis of N-Unsubstituted beta-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines 114
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity (vol 61, pg 11270, 2005) 114
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl) benzamidines by reaction of halobenzonitriles with lithium amides 113
Synthesis of N,N,N',N'-tetraalkylbenzidines through oxidative coupling of N,N-dialkylarylamines induced by SbCl5 113
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 111
Upregulation of beta 3-adrenergic receptor mRNA in human colon cancer: a preliminary study 110
Single-dose extended-toxicity preclinical study on novel radiotracer formulations for use in the diagnosis of neuroendocrine tumor and neurodegenerative disorders 110
Synthesis and Biological Evaluation of New Clofibrate Analogues as Potential PPARa Agonists 109
Optically active sulfoxides by enantiospecific reactions of bromovinyl aryl sulfoxides with Grignard reagents 108
Reaction of 3-phenylisoxazole with alkyllithiums 108
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 108
Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones 107
Novel pyrazoles and their radiolabeled derivatives useful as COX-1 selective inhibitors 106
3-Substituted-5-phenylthio-2-isoxazolines: synthesis and reactions with bases 106
Synthesis of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles by reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde 105
Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon motility control 105
Isoxazole derivatives and their use as cyclooxygenase inhibitors 105
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
[18F]-P6 AS A CYCLOOXYGENASE-1 TARGETED IMAGING AGENT 103
Selective COX-1 inhibition: a therapeutic target to be reconsidered 102
Stereospecific synthesis and absolute configuration of Mexiletine 102
Derivati isossazolici e loro impiego come inibitori della ciclossigenasi 102
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists 101
Bioethanol from biomass model fermentation by Kluyvromyces marxianus CBS6556 100
Screening on the use of Kluyveromyces marxianus CBS 6556 growing cells as enantioselective biocatalyst for ketones reduction 99
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 98
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 98
Five-member-ring heterocycles by reacting enolates with dipoles 95
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 93
Synthesis of N,N-dialkylaminobenzonitriles and halo-(N,N-dialkyl)benzamidines by reaction of halobenzonitriles with lithium amides 93
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 92
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 92
BETA-3 RECEPTOR LIGANDS AND THEIR USE IN THERAPY 92
Biocatalytic resolution of (+/-)-hydroxyalkanoic esters. A strategy for enhancing the enantiomeric specificity of lipase-catalyzed ester hydrolysis 92
A Chemoenzymatic Route to Enantiomerically Pure ϖ-Trimethylsilil Polyunsaturated Secondary Alcohols 91
C-Alkylation and Michael Addition Involving the Polymer - Supported Carbanion from Methyl Nitroacetate 91
An efficient C2-homologation of aromatic aldehydes via 5-hydroxyisoxazolidines 91
Diastereo- and enantio-selective bioreduction of ethyl 2-(4-chlorophenoxy)-3-oxobutanoate clofibrate analogues by Kluyveromyces marxianus and other whole cell biocatalysts 91
Regiocontrol by anchimeric coordination in the reactions of organocopper reagents with allylic substrates bearing two leaving groups. Synthesis of optically active homoallylic alcohols 90
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 90
Myogenic effect of SP-1f and SP-1h two novel 3-adrenoceptor (3-AR) agonists in human colonic circular smooth muscle 90
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 89
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 88
Chelation-controlled chemo-, regio- and enantio-selective synthesis of homoallylic alcohols 88
Decomposition of aryl azides by THF-butyllithium. II. Isolation of 1-aryl-4,5-dihydro-5-hydroxy-1H-1,2,3-triazoles 88
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 87
Zoledronic acid as a novel dual blocker of KIR6.1/2-SUR2 subunits of ATP-sensitive K+ channels: Role in the adverse drug reactions 87
Potent and stereoselective use-dependent block muscle Na+ channels by a new proline-like tocainide derivative 86
Optically active Mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 86
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 85
Totale 12.104
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Categoria #
all - tutte 91.151
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 91.151
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.160 0 0 0 0 0 65 153 87 220 291 207 137
2021/20221.614 71 251 27 50 83 107 67 81 104 100 259 414
2022/20232.686 396 251 189 251 370 344 22 295 417 32 65 54
2023/20241.142 67 164 66 71 89 216 56 51 150 64 31 117
2024/20254.124 144 66 353 135 148 311 412 388 225 189 533 1.220
2025/20264.574 1.191 411 826 1.042 996 108 0 0 0 0 0 0
Totale 21.987