In medicinal chemistry, there is a plenty of evidences that the replacement of a hydrogen atom with a fluorine atom determines a number of advantages, such as the improvement of pharmacokinetic and pharmacodynamic profiles of APIs through the modification of their physicochemical and biopharmacological properties.
Current and emerging applications of fluorine in medicinal chemistry
PERRONE, MARIA GRAZIA;VITALE, PAOLA;PANELLA, ANDREA;SCILIMATI, Antonio
2015-01-01
Abstract
In medicinal chemistry, there is a plenty of evidences that the replacement of a hydrogen atom with a fluorine atom determines a number of advantages, such as the improvement of pharmacokinetic and pharmacodynamic profiles of APIs through the modification of their physicochemical and biopharmacological properties.File in questo prodotto:
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