A multistep gram-scale synthesis of (S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate (2) has been developed. The title compound was prepared starting from commercially available L-DOPA which was O-and N-protected before undergoing iodination by CF 3 CO 2 Ag/I 2 . The structure of the target compound was confirmed using IR, 1 H-NMR, 13 C-NMR, 2D (COSY, HSQC) NMR spectroscopy, as well as ESI-MS and HRMS.
CAVALLUZZI, MARIA MADDALENA (Corresponding)
|Data di pubblicazione:||2019|
|Appare nelle tipologie:||1.1 Articolo in rivista|