IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 5.623
EU - Europa 3.171
AS - Asia 2.950
SA - Sud America 654
AF - Africa 115
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 5
Totale 12.551
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Nazione #
US - Stati Uniti d'America 5.462
SG - Singapore 1.086
IT - Italia 1.048
CN - Cina 700
DE - Germania 556
BR - Brasile 524
SE - Svezia 390
HK - Hong Kong 338
RU - Federazione Russa 333
VN - Vietnam 289
GB - Regno Unito 240
FI - Finlandia 127
FR - Francia 112
UA - Ucraina 110
CA - Canada 103
IN - India 96
BD - Bangladesh 76
JP - Giappone 49
NL - Olanda 46
ID - Indonesia 42
AR - Argentina 40
MX - Messico 38
IQ - Iraq 37
CI - Costa d'Avorio 34
TR - Turchia 34
AU - Australia 32
PL - Polonia 30
BE - Belgio 29
CH - Svizzera 29
PK - Pakistan 25
EC - Ecuador 22
CZ - Repubblica Ceca 21
IE - Irlanda 20
CO - Colombia 19
ES - Italia 19
IR - Iran 18
KR - Corea 18
SA - Arabia Saudita 18
ZA - Sudafrica 17
PH - Filippine 15
TW - Taiwan 15
AT - Austria 14
CL - Cile 14
UZ - Uzbekistan 14
VE - Venezuela 14
MA - Marocco 12
TN - Tunisia 11
IL - Israele 10
MY - Malesia 10
LT - Lituania 9
PY - Paraguay 9
AZ - Azerbaigian 8
EG - Egitto 8
KE - Kenya 8
NP - Nepal 8
AE - Emirati Arabi Uniti 6
HU - Ungheria 6
LB - Libano 6
PE - Perù 6
TH - Thailandia 6
JO - Giordania 5
NO - Norvegia 5
GE - Georgia 4
GT - Guatemala 4
JM - Giamaica 4
KZ - Kazakistan 4
PT - Portogallo 4
UY - Uruguay 4
DZ - Algeria 3
EE - Estonia 3
ET - Etiopia 3
EU - Europa 3
MD - Moldavia 3
QA - Qatar 3
SN - Senegal 3
AL - Albania 2
BB - Barbados 2
BG - Bulgaria 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
LY - Libia 2
OM - Oman 2
RO - Romania 2
RS - Serbia 2
SC - Seychelles 2
TT - Trinidad e Tobago 2
TZ - Tanzania 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BT - Bhutan 1
BW - Botswana 1
BY - Bielorussia 1
CR - Costa Rica 1
CY - Cipro 1
FJ - Figi 1
GI - Gibilterra 1
Totale 12.530
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Città #
Los Angeles 656
Singapore 546
Ashburn 532
Chandler 398
San Jose 388
Hong Kong 327
Fairfield 291
Milan 245
Beijing 243
Jacksonville 231
Nyköping 228
Woodbridge 198
Bari 192
Dallas 174
Houston 163
Ann Arbor 156
Dong Ket 126
Cambridge 122
Wilmington 115
New York 109
Seattle 105
Rome 88
Columbus 71
Lauterbourg 71
Nanjing 70
Lawrence 67
Roxbury 65
Boardman 61
Sannicandro di Bari 58
Helsinki 56
Ho Chi Minh City 55
São Paulo 55
Council Bluffs 53
Brooklyn 48
Princeton 40
Des Moines 39
Santa Clara 39
Tokyo 36
Hanoi 35
Munich 35
Abidjan 34
Vancouver 30
Buffalo 29
London 29
Brussels 28
Denver 28
San Francisco 27
Inglewood 25
Warsaw 25
Frankfurt am Main 23
Hebei 23
Toronto 22
Chicago 21
Jakarta 21
Turin 21
Atlanta 20
Catania 20
Falkenstein 20
Orem 19
Shanghai 19
Brno 18
Dearborn 18
Dublin 18
Jiaxing 18
Montreal 17
San Diego 17
Shenyang 16
Turku 16
Nanchang 15
Phoenix 15
Stockholm 15
Baghdad 14
Bern 14
Chennai 14
Pune 14
Taranto 14
Bitonto 13
Moscow 13
North Bergen 13
Rio de Janeiro 13
Tashkent 13
Belo Horizonte 12
Boston 12
New Delhi 12
Nuremberg 12
Amsterdam 11
Mumbai 11
Naples 11
Augusta 10
Florence 10
Haiphong 10
Manchester 10
Mexico City 10
Palermo 10
Poplar 10
Santiago 10
Sydney 10
Taipei 10
Tianjin 10
Waltham 10
Totale 7.590
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Nome #
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 288
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 253
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 245
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 214
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 211
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 204
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 200
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 192
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 190
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 190
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 189
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 185
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 185
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 184
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 183
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 183
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 181
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 176
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 172
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 170
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 168
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 166
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 162
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 159
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 159
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 158
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 154
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 150
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 149
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 148
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 146
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ(8)-Δ(7) Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity 146
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 141
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 140
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 138
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 137
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 135
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 134
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 130
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 127
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 126
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 124
34. Methyl substitution on the piperidine ring of N-[ -(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma-1 receptor 123
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 121
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 121
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 119
Three-dimensional structure of human cyclooxygenase (hCOX)-1 119
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 118
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 118
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 117
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 117
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 116
Translational Theragnosis of Ovarian Cancer: where do we stand? 115
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 114
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 113
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 113
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 108
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 108
Three-dimensional structure of human cyclooxygenase (hCOX)-1 108
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 104
Novel hClpP protease activators with potential anticancer activity in DIPG patients 103
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 102
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 99
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 97
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 97
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 95
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 95
Ovine COX-1 Isoenzyme Bio-production 95
TARGETING HUMAN MITOCHONDRIAL ClpP AS A NOVEL THERAPEUTIC APPROACH TO H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 94
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 93
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 92
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 91
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 91
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 90
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 89
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 88
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 87
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 86
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 85
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 82
Why PB28 Could Be a Covid 2019 Game Changer? 82
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 81
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 79
null 79
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 73
Inside circular economy challenges: “green” application to valorise olive mill wastewater 72
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 71
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 71
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 70
Mitochondrial Protease ClpP: Cancer Marker and Drug Target 68
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 68
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 67
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 67
Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy 67
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 66
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 64
Structural simplification of imipridones to speed up the knowledge on the nature of the interactions with the human ClpP, a mitochondrial protease strictly linked to DIPG 63
Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood–Brain Barrier Obstacle? 62
Dissociazione di effetti farmacologici in composti chirali 62
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 61
Totale 12.508
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Categoria #
all - tutte 47.425
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.425
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022673 26 88 5 44 40 68 42 39 47 41 100 133
2022/20231.037 148 121 74 91 137 128 8 118 164 10 22 16
2023/2024549 26 67 23 43 44 87 26 16 103 37 21 56
2024/20251.986 95 30 144 77 92 138 259 179 117 101 248 506
2025/20264.841 547 254 374 503 562 283 535 177 509 438 228 431
2026/2027833 833 0 0 0 0 0 0 0 0 0 0 0
Totale 12.857