IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 2.834
EU - Europa 1.675
AS - Asia 524
SA - Sud America 14
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
AF - Africa 1
Totale 5.054
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Nazione #
US - Stati Uniti d'America 2.825
DE - Germania 445
IT - Italia 369
SE - Svezia 365
CN - Cina 336
GB - Regno Unito 158
UA - Ucraina 103
VN - Vietnam 95
RU - Federazione Russa 86
FI - Finlandia 61
IN - India 25
BE - Belgio 23
SG - Singapore 22
CZ - Repubblica Ceca 19
FR - Francia 13
IE - Irlanda 13
IR - Iran 13
JP - Giappone 11
CL - Cile 9
CA - Canada 7
HU - Ungheria 4
KR - Corea 4
NL - Olanda 4
PE - Perù 4
AU - Australia 3
EU - Europa 3
ID - Indonesia 3
IQ - Iraq 3
CH - Svizzera 2
ES - Italia 2
HK - Hong Kong 2
IL - Israele 2
MX - Messico 2
RO - Romania 2
TH - Thailandia 2
TW - Taiwan 2
AT - Austria 1
BG - Bulgaria 1
CO - Colombia 1
DK - Danimarca 1
EE - Estonia 1
GE - Georgia 1
MY - Malesia 1
NO - Norvegia 1
PK - Pakistan 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
ZW - Zimbabwe 1
Totale 5.054
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Città #
Chandler 407
Fairfield 291
Jacksonville 230
Nyköping 225
Woodbridge 189
Ashburn 171
Houston 154
Ann Arbor 150
Bari 146
Cambridge 117
Wilmington 115
Seattle 100
Dong Ket 95
Beijing 77
Lawrence 67
Nanjing 67
Roxbury 64
Sannicandro di Bari 59
New York 49
Boardman 41
Des Moines 39
Princeton 38
Brooklyn 35
Inglewood 25
Brussels 23
Hebei 23
Los Angeles 20
Brno 18
Dearborn 18
Jiaxing 18
San Diego 16
Shenyang 15
Shanghai 14
Singapore 14
Milan 13
Nanchang 13
Dublin 12
Pune 11
London 10
Bitonto 9
Tianjin 9
Tokyo 9
Wuhan 9
Ardabil 8
Augusta 8
Leawood 8
San Mateo 8
Guangzhou 7
Rome 7
Santiago 7
Hefei 6
Helsinki 6
San Francisco 6
Turin 6
Catania 5
Changsha 5
Jinan 5
Kansas City 5
Paris 5
Arequipa 4
Boydton 4
Casoria 4
Jinhua 4
Kornye 4
Monmouth Junction 4
Napoli 4
Redwood City 4
Taranto 4
Toronto 4
Valparaiso 4
Wallsend 4
Wuxi 4
Auburn Hills 3
Chicago 3
Falls Church 3
Kiev 3
Kilburn 3
Massafra 3
Norwalk 3
Prescot 3
Racale 3
Stanford 3
Sulaymaniyah 3
Washington 3
Alexandria 2
Altamura 2
Asti 2
Bangkok 2
Baotou 2
Bedford 2
Bologna 2
Brisbane 2
Coimbatore 2
Grottaglie 2
Hemel Hempstead 2
Irving 2
Kunming 2
Madrid 2
Marseille 2
Messina 2
Totale 3.447
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Nome #
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 149
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 130
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 130
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 126
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 125
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 119
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 118
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 114
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 108
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 108
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 107
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 105
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 103
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 100
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 97
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 97
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 97
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 94
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 94
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 92
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 91
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 91
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 90
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 85
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 84
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 83
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 82
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 80
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 80
null 79
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 78
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 75
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 72
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 71
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 68
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 64
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 64
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 61
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 59
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 58
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 57
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 57
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 54
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 54
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 52
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 51
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 49
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 48
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 48
null 47
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 47
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 43
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 43
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 41
Three-dimensional structure of human cyclooxygenase (hCOX)-1 41
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 40
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 39
Ovine COX-1 Isoenzyme Bio-production 39
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 38
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 37
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 37
Why PB28 Could Be a Covid 2019 Game Changer? 37
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 35
Translational Theragnosis of Ovarian Cancer: where do we stand? 33
Riduzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 33
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 32
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 32
Modificazione della cute umana dopo trattamento con geli acquosi di acido tartarico 29
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 29
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 29
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 26
EFFECTS OF CHIRAL CARBOXYLIC ACIDS ON IONIC CHANNELS OF SKELETAL MUSCLE MEMBRANE. 25
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 20
Dissociazione di effetti farmacologici in composti chirali 19
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 18
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 17
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 17
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 15
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 15
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 14
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 12
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 12
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 11
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 10
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 10
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 8
Inside circular economy challenges: “green” application to valorise olive mill wastewater 6
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 5
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 5
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 4
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 4
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 1
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 1
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 1
Totale 5.255
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Categoria #
all - tutte 21.766
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.766
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020768 0 54 36 75 80 47 103 65 93 92 103 20
2020/2021852 74 46 71 63 79 55 51 28 76 93 88 128
2021/2022665 26 86 5 41 40 68 42 38 46 42 99 132
2022/20231.045 146 125 77 92 139 128 7 121 163 9 22 16
2023/2024552 29 68 24 43 45 85 26 15 103 38 20 56
2024/2025117 95 22 0 0 0 0 0 0 0 0 0 0
Totale 5.255