IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 4.636
AS - Asia 2.868
EU - Europa 2.723
SA - Sud America 649
AF - Africa 113
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 5
Totale 11.027
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Nazione #
US - Stati Uniti d'America 4.522
SG - Singapore 1.070
CN - Cina 684
IT - Italia 623
DE - Germania 556
BR - Brasile 521
SE - Svezia 390
RU - Federazione Russa 333
HK - Hong Kong 328
VN - Vietnam 288
GB - Regno Unito 239
FI - Finlandia 127
FR - Francia 110
UA - Ucraina 110
IN - India 95
CA - Canada 63
JP - Giappone 49
NL - Olanda 45
ID - Indonesia 42
BD - Bangladesh 40
AR - Argentina 39
MX - Messico 38
IQ - Iraq 37
CI - Costa d'Avorio 34
TR - Turchia 34
AU - Australia 32
BE - Belgio 29
PL - Polonia 28
PK - Pakistan 24
CZ - Repubblica Ceca 21
EC - Ecuador 21
IE - Irlanda 20
CO - Colombia 19
ES - Italia 19
IR - Iran 18
KR - Corea 18
CH - Svizzera 17
SA - Arabia Saudita 17
ZA - Sudafrica 17
PH - Filippine 15
TW - Taiwan 15
AT - Austria 14
CL - Cile 14
UZ - Uzbekistan 14
VE - Venezuela 14
MA - Marocco 12
TN - Tunisia 11
IL - Israele 10
MY - Malesia 10
LT - Lituania 9
PY - Paraguay 9
AZ - Azerbaigian 8
EG - Egitto 8
KE - Kenya 8
NP - Nepal 8
AE - Emirati Arabi Uniti 6
HU - Ungheria 6
LB - Libano 6
PE - Perù 6
TH - Thailandia 6
JO - Giordania 5
NO - Norvegia 5
GE - Georgia 4
KZ - Kazakistan 4
UY - Uruguay 4
DZ - Algeria 3
EE - Estonia 3
ET - Etiopia 3
EU - Europa 3
JM - Giamaica 3
QA - Qatar 3
SN - Senegal 3
BB - Barbados 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GT - Guatemala 2
LY - Libia 2
MD - Moldavia 2
OM - Oman 2
PT - Portogallo 2
RO - Romania 2
RS - Serbia 2
TZ - Tanzania 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BO - Bolivia 1
BT - Bhutan 1
BW - Botswana 1
BY - Bielorussia 1
CY - Cipro 1
FJ - Figi 1
GI - Gibilterra 1
GM - Gambi 1
HR - Croazia 1
KN - Saint Kitts e Nevis 1
Totale 11.010
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Città #
Singapore 541
Ashburn 504
Chandler 397
San Jose 328
Hong Kong 318
Fairfield 291
Beijing 237
Jacksonville 230
Nyköping 228
Woodbridge 198
Bari 180
Dallas 168
Houston 162
Ann Arbor 156
Dong Ket 126
Cambridge 122
Wilmington 115
Seattle 105
Los Angeles 92
New York 88
Lauterbourg 71
Nanjing 70
Lawrence 67
Roxbury 65
Sannicandro di Bari 58
Helsinki 56
Ho Chi Minh City 54
São Paulo 54
Council Bluffs 51
Boardman 47
Brooklyn 47
Des Moines 39
Princeton 39
Tokyo 36
Hanoi 35
Munich 35
Abidjan 34
Santa Clara 34
London 29
Milan 29
Brussels 28
Inglewood 25
San Francisco 25
Warsaw 25
Denver 23
Frankfurt am Main 23
Hebei 23
Rome 23
Buffalo 22
Jakarta 21
Toronto 21
Chicago 20
Falkenstein 20
Brno 18
Dearborn 18
Dublin 18
Jiaxing 18
Orem 18
Shanghai 18
Catania 17
San Diego 17
Shenyang 16
Turku 16
Montreal 15
Nanchang 15
Stockholm 15
Atlanta 14
Baghdad 14
Pune 14
Bitonto 13
Chennai 13
Moscow 13
Rio de Janeiro 13
Tashkent 13
Belo Horizonte 12
Boston 12
New Delhi 12
North Bergen 12
Nuremberg 12
Amsterdam 11
Mumbai 11
Turin 11
Augusta 10
Haiphong 10
Manchester 10
Mexico City 10
Phoenix 10
Poplar 10
Santiago 10
Sydney 10
Taipei 10
Waltham 10
City of London 9
Guangzhou 9
Johannesburg 9
Romola 9
The Dalles 9
Tianjin 9
Wuhan 9
Ardabil 8
Totale 6.425
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Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 236
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 225
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 204
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 201
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 190
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 183
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 180
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 178
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 176
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 176
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 176
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 173
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 170
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 153
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 152
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 150
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 149
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 148
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 147
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 144
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 143
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 142
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 140
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 139
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ(8)-Δ(7) Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity 138
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 137
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 137
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 137
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 128
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 125
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 125
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 123
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 122
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 122
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 121
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 120
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 116
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 116
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 116
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 113
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 111
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 110
34. Methyl substitution on the piperidine ring of N-[ -(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma-1 receptor 110
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 108
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 108
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 107
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 107
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 107
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 106
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 106
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 105
Translational Theragnosis of Ovarian Cancer: where do we stand? 105
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 103
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 102
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 102
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 100
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 97
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 96
Three-dimensional structure of human cyclooxygenase (hCOX)-1 96
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 95
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 94
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 90
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 87
TARGETING HUMAN MITOCHONDRIAL ClpP AS A NOVEL THERAPEUTIC APPROACH TO H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 87
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 86
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 86
Ovine COX-1 Isoenzyme Bio-production 85
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 84
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 83
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 83
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 83
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 81
Novel hClpP protease activators with potential anticancer activity in DIPG patients 80
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 80
null 79
Why PB28 Could Be a Covid 2019 Game Changer? 78
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 77
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 75
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 75
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 74
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 70
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 68
Inside circular economy challenges: “green” application to valorise olive mill wastewater 67
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 67
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 67
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 65
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 64
Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy 64
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 63
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 63
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 61
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 61
Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood–Brain Barrier Obstacle? 59
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 59
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 59
Riduzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 59
Mitochondrial Protease ClpP: Cancer Marker and Drug Target 54
Dissociazione di effetti farmacologici in composti chirali 53
Modificazione della cute umana dopo trattamento con geli acquosi di acido tartarico 52
Three-dimensional structure of human cyclooxygenase (hCOX)-1 51
Totale 11.025
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Categoria #
all - tutte 42.946
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.946
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021333 0 0 0 0 0 0 0 0 0 87 89 157
2021/2022673 26 88 5 44 40 68 42 39 47 41 100 133
2022/20231.037 148 121 74 91 137 128 8 118 164 10 22 16
2023/2024549 26 67 23 43 44 87 26 16 103 37 21 56
2024/20251.986 95 30 144 77 92 138 259 179 117 101 248 506
2025/20264.128 547 254 374 503 562 283 535 177 509 384 0 0
Totale 11.311