IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 2.890
EU - Europa 1.736
AS - Asia 675
SA - Sud America 20
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 3
AF - Africa 2
Totale 5.333
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Nazione #
US - Stati Uniti d'America 2.866
DE - Germania 454
IT - Italia 407
SE - Svezia 366
CN - Cina 349
GB - Regno Unito 159
SG - Singapore 154
UA - Ucraina 104
VN - Vietnam 95
RU - Federazione Russa 86
FI - Finlandia 61
IN - India 26
BE - Belgio 24
CA - Canada 22
CZ - Repubblica Ceca 19
FR - Francia 14
IE - Irlanda 14
IR - Iran 13
JP - Giappone 13
CL - Cile 9
NL - Olanda 8
AU - Australia 7
ID - Indonesia 5
BR - Brasile 4
CH - Svizzera 4
HU - Ungheria 4
KR - Corea 4
PE - Perù 4
EU - Europa 3
HK - Hong Kong 3
IQ - Iraq 3
AT - Austria 2
ES - Italia 2
IL - Israele 2
MX - Messico 2
RO - Romania 2
TH - Thailandia 2
TW - Taiwan 2
AR - Argentina 1
BG - Bulgaria 1
CO - Colombia 1
DK - Danimarca 1
EE - Estonia 1
GE - Georgia 1
LT - Lituania 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
PK - Pakistan 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
VE - Venezuela 1
ZW - Zimbabwe 1
Totale 5.333
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Città #
Chandler 407
Fairfield 289
Jacksonville 230
Nyköping 225
Woodbridge 188
Ashburn 173
Houston 153
Bari 150
Ann Arbor 149
Cambridge 116
Singapore 114
Wilmington 114
Seattle 100
Dong Ket 95
Beijing 77
Nanjing 67
Lawrence 66
Roxbury 63
Sannicandro di Bari 58
New York 49
Boardman 42
Des Moines 38
Princeton 38
Brooklyn 35
Inglewood 25
Brussels 24
Hebei 23
Los Angeles 21
Brno 18
Dearborn 18
Jiaxing 18
San Diego 16
Milan 15
Shanghai 15
Shenyang 15
Bitonto 13
Dublin 13
Nanchang 13
Santa Clara 13
Toronto 13
London 11
Pune 11
Munich 9
Romola 9
Tianjin 9
Tokyo 9
Wuhan 9
Ardabil 8
Augusta 8
Leawood 8
San Mateo 8
Guangzhou 7
Rome 7
Santiago 7
Hefei 6
Helsinki 6
San Francisco 6
Turin 6
Catania 5
Changsha 5
Jinan 5
Kansas City 5
Paris 5
Adelaide 4
Arequipa 4
Boydton 4
Casoria 4
Jinhua 4
Kornye 4
Lincoln 4
Monmouth Junction 4
Napoli 4
Redwood City 4
Taranto 4
Valparaiso 4
Wallsend 4
Wuxi 4
Auburn Hills 3
Chicago 3
Falls Church 3
Florence 3
Kiev 3
Kilburn 3
Massafra 3
Norwalk 3
Parma 3
Racale 3
Stanford 3
Sulaymaniyah 3
Washington 3
Alexandria 2
Altamura 2
Asti 2
Bangkok 2
Baotou 2
Bedford 2
Bologna 2
Brisbane 2
Chur 2
Coimbatore 2
Totale 3.593
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Nome #
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 152
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 150
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 132
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 131
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 131
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 120
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 119
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 117
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 112
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 111
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 110
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 107
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 106
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 103
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 101
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 101
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 99
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 98
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 96
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 94
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 93
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 93
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 93
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 91
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 89
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 87
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 84
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 82
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 81
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 81
null 79
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 78
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 75
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 74
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 70
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 66
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 65
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 65
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 64
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 63
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 60
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 59
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 59
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 57
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 55
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 55
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 54
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 53
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 52
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 49
null 48
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 46
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 46
Three-dimensional structure of human cyclooxygenase (hCOX)-1 45
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 44
Why PB28 Could Be a Covid 2019 Game Changer? 44
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 41
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 41
Ovine COX-1 Isoenzyme Bio-production 41
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 40
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 40
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 39
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 37
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 36
Translational Theragnosis of Ovarian Cancer: where do we stand? 36
Riduzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 35
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 34
Modificazione della cute umana dopo trattamento con geli acquosi di acido tartarico 31
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 30
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 29
EFFECTS OF CHIRAL CARBOXYLIC ACIDS ON IONIC CHANNELS OF SKELETAL MUSCLE MEMBRANE. 27
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 27
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 26
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 25
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 20
Dissociazione di effetti farmacologici in composti chirali 20
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 19
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 18
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 18
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 17
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 17
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 16
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 13
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 13
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 12
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 12
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 11
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 10
Inside circular economy challenges: “green” application to valorise olive mill wastewater 9
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 7
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 6
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 6
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 3
Totale 5.551
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Categoria #
all - tutte 24.396
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.396
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020603 0 0 0 0 80 47 103 65 93 92 103 20
2020/2021844 74 46 71 63 79 55 51 28 76 87 88 126
2021/2022659 26 86 5 41 40 67 42 38 46 40 98 130
2022/20231.043 145 125 76 92 139 128 7 121 163 9 22 16
2023/2024550 29 68 24 43 44 85 26 15 103 37 20 56
2024/2025431 95 30 140 78 88 0 0 0 0 0 0 0
Totale 5.551