IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 6.032
EU - Europa 3.214
AS - Asia 2.980
SA - Sud America 663
Continente sconosciuto - Info sul continente non disponibili 312
AF - Africa 117
OC - Oceania 33
Totale 13.351
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Nazione #
US - Stati Uniti d'America 5.859
SG - Singapore 1.093
IT - Italia 1.078
CN - Cina 705
DE - Germania 557
BR - Brasile 526
SE - Svezia 390
HK - Hong Kong 338
RU - Federazione Russa 333
VN - Vietnam 289
GB - Regno Unito 242
FI - Finlandia 127
FR - Francia 119
UA - Ucraina 110
CA - Canada 107
IN - India 97
BD - Bangladesh 87
JP - Giappone 49
NL - Olanda 47
ID - Indonesia 43
AR - Argentina 42
MX - Messico 39
IQ - Iraq 37
CI - Costa d'Avorio 34
TR - Turchia 34
AU - Australia 32
BE - Belgio 30
PL - Polonia 30
CH - Svizzera 29
PK - Pakistan 26
EC - Ecuador 25
CZ - Repubblica Ceca 21
CO - Colombia 20
IE - Irlanda 20
ES - Italia 19
SA - Arabia Saudita 19
IR - Iran 18
KR - Corea 18
ZA - Sudafrica 17
PH - Filippine 15
TW - Taiwan 15
VE - Venezuela 15
AT - Austria 14
CL - Cile 14
UZ - Uzbekistan 14
MA - Marocco 12
MY - Malesia 11
TN - Tunisia 11
IL - Israele 10
KE - Kenya 9
LT - Lituania 9
PY - Paraguay 9
AZ - Azerbaigian 8
EG - Egitto 8
NP - Nepal 8
TH - Thailandia 8
AE - Emirati Arabi Uniti 6
HU - Ungheria 6
JM - Giamaica 6
LB - Libano 6
PE - Perù 6
GT - Guatemala 5
JO - Giordania 5
NO - Norvegia 5
TT - Trinidad e Tobago 5
GE - Georgia 4
KZ - Kazakistan 4
PT - Portogallo 4
UY - Uruguay 4
DZ - Algeria 3
EE - Estonia 3
ET - Etiopia 3
EU - Europa 3
MD - Moldavia 3
QA - Qatar 3
SN - Senegal 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
BB - Barbados 2
BG - Bulgaria 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
HR - Croazia 2
LY - Libia 2
NG - Nigeria 2
OM - Oman 2
RO - Romania 2
RS - Serbia 2
SC - Seychelles 2
TZ - Tanzania 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BT - Bhutan 1
BW - Botswana 1
BY - Bielorussia 1
CR - Costa Rica 1
CY - Cipro 1
Totale 13.023
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Città #
Los Angeles 667
Singapore 551
Ashburn 542
San Jose 483
Chandler 398
Hong Kong 327
Fairfield 291
Milan 248
Beijing 244
Jacksonville 231
Nyköping 228
Woodbridge 199
Bari 192
Council Bluffs 182
Dallas 179
Houston 163
Ann Arbor 156
Dong Ket 126
Cambridge 122
New York 115
Wilmington 115
Seattle 108
Rome 96
Columbus 71
Lauterbourg 71
Nanjing 70
Lawrence 67
Roxbury 65
Boardman 62
Sannicandro di Bari 58
Helsinki 56
São Paulo 56
Ho Chi Minh City 55
Santa Clara 51
Brooklyn 48
Princeton 40
Des Moines 39
Tokyo 36
Hanoi 35
Munich 35
Abidjan 34
Buffalo 31
London 30
Vancouver 30
Denver 29
Brussels 28
San Francisco 28
Phoenix 26
Chicago 25
Inglewood 25
Warsaw 25
Frankfurt am Main 24
Hebei 23
Toronto 23
Jakarta 21
Turin 21
Atlanta 20
Catania 20
Falkenstein 20
Shanghai 20
Orem 19
Brno 18
Dearborn 18
Dublin 18
Jiaxing 18
Montreal 17
San Diego 17
Shenyang 16
Turku 16
Nanchang 15
North Bergen 15
Stockholm 15
Baghdad 14
Bern 14
Bitonto 14
Chennai 14
Pune 14
Taranto 14
Moscow 13
Rio de Janeiro 13
Tashkent 13
Amsterdam 12
Belo Horizonte 12
Boston 12
Naples 12
New Delhi 12
Nuremberg 12
Florence 11
Mumbai 11
Philadelphia 11
Augusta 10
Guayaquil 10
Haiphong 10
Manchester 10
Memphis 10
Mexico City 10
Palermo 10
Poplar 10
Santiago 10
Sydney 10
Totale 7.911
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Nome #
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 297
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 261
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 252
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 216
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 214
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 210
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 206
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 197
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 195
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 193
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 193
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 188
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 187
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 186
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 185
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 185
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 184
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 178
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 178
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 176
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 176
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 170
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 168
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 165
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 165
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 162
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 160
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 153
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 153
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ(8)-Δ(7) Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity 152
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 152
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 146
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 146
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 144
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 143
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 143
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 140
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 140
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 136
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 130
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 130
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 130
34. Methyl substitution on the piperidine ring of N-[ -(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma-1 receptor 128
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 127
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 126
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 122
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 122
Three-dimensional structure of human cyclooxygenase (hCOX)-1 121
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 121
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 121
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 120
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 120
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 120
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 118
Translational Theragnosis of Ovarian Cancer: where do we stand? 118
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 116
Three-dimensional structure of human cyclooxygenase (hCOX)-1 114
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 113
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 112
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 112
Novel hClpP protease activators with potential anticancer activity in DIPG patients 111
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 109
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 109
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 106
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 102
TARGETING HUMAN MITOCHONDRIAL ClpP AS A NOVEL THERAPEUTIC APPROACH TO H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 102
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 101
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 101
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 98
Ovine COX-1 Isoenzyme Bio-production 97
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 96
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 96
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 96
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 94
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 94
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 94
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 94
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 89
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 88
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 87
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 86
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 85
Why PB28 Could Be a Covid 2019 Game Changer? 85
null 79
Inside circular economy challenges: “green” application to valorise olive mill wastewater 78
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 78
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 76
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 75
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 75
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 74
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 72
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 72
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 71
Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy 70
Structural simplification of imipridones to speed up the knowledge on the nature of the interactions with the human ClpP, a mitochondrial protease strictly linked to DIPG 69
Mitochondrial Protease ClpP: Cancer Marker and Drug Target 68
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 67
Dissociazione di effetti farmacologici in composti chirali 65
Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood–Brain Barrier Obstacle? 64
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 64
Totale 12.973
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Categoria #
all - tutte 49.029
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.029
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022559 0 0 5 44 40 68 42 39 47 41 100 133
2022/20231.037 148 121 74 91 137 128 8 118 164 10 22 16
2023/2024549 26 67 23 43 44 87 26 16 103 37 21 56
2024/20251.986 95 30 144 77 92 138 259 179 117 101 248 506
2025/20264.841 547 254 374 503 562 283 535 177 509 438 228 431
2026/20271.327 860 266 201 0 0 0 0 0 0 0 0 0
Totale 13.351