IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 6.824
EU - Europa 3.339
AS - Asia 2.990
SA - Sud America 684
Continente sconosciuto - Info sul continente non disponibili 323
AF - Africa 117
OC - Oceania 33
Totale 14.310
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Nazione #
US - Stati Uniti d'America 6.528
IT - Italia 1.153
SG - Singapore 1.096
CN - Cina 707
DE - Germania 565
BR - Brasile 545
SE - Svezia 390
RU - Federazione Russa 339
HK - Hong Kong 338
VN - Vietnam 289
GB - Regno Unito 266
CA - Canada 161
FI - Finlandia 127
FR - Francia 121
UA - Ucraina 110
IN - India 97
BD - Bangladesh 88
JP - Giappone 49
NL - Olanda 47
ID - Indonesia 43
AR - Argentina 42
MX - Messico 40
IQ - Iraq 37
CI - Costa d'Avorio 34
TR - Turchia 34
AU - Australia 32
BE - Belgio 30
PL - Polonia 30
CH - Svizzera 29
EC - Ecuador 26
PK - Pakistan 26
IE - Irlanda 24
CZ - Repubblica Ceca 21
CO - Colombia 20
ES - Italia 20
SA - Arabia Saudita 19
IR - Iran 18
KR - Corea 18
ZA - Sudafrica 17
VE - Venezuela 16
PH - Filippine 15
TW - Taiwan 15
AT - Austria 14
CL - Cile 14
UZ - Uzbekistan 14
CR - Costa Rica 13
IL - Israele 12
MA - Marocco 12
MY - Malesia 12
SV - El Salvador 12
GT - Guatemala 11
TN - Tunisia 11
NI - Nicaragua 10
CW - ???statistics.table.value.countryCode.CW??? 9
KE - Kenya 9
LT - Lituania 9
PR - Porto Rico 9
PY - Paraguay 9
TH - Thailandia 9
AZ - Azerbaigian 8
EG - Egitto 8
JM - Giamaica 8
NP - Nepal 8
TT - Trinidad e Tobago 8
HN - Honduras 7
AE - Emirati Arabi Uniti 6
EE - Estonia 6
HU - Ungheria 6
LB - Libano 6
PE - Perù 6
GP - Guadalupe 5
JO - Giordania 5
NO - Norvegia 5
BB - Barbados 4
GE - Georgia 4
KZ - Kazakistan 4
PT - Portogallo 4
UY - Uruguay 4
DZ - Algeria 3
ET - Etiopia 3
EU - Europa 3
MD - Moldavia 3
QA - Qatar 3
SN - Senegal 3
XK - ???statistics.table.value.countryCode.XK??? 3
AL - Albania 2
BG - Bulgaria 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GR - Grecia 2
HR - Croazia 2
KN - Saint Kitts e Nevis 2
LY - Libia 2
NG - Nigeria 2
OM - Oman 2
RO - Romania 2
RS - Serbia 2
SC - Seychelles 2
TZ - Tanzania 2
Totale 13.974
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Città #
Ashburn 723
Los Angeles 671
Singapore 551
San Jose 539
Chandler 398
Hong Kong 327
Fairfield 291
Milan 253
Beijing 244
Jacksonville 231
Nyköping 228
Council Bluffs 220
Bari 208
Woodbridge 199
Dallas 182
Houston 163
Ann Arbor 156
New York 127
Dong Ket 126
Cambridge 123
Wilmington 115
Seattle 109
Rome 106
São Paulo 73
Columbus 72
Lauterbourg 71
Nanjing 70
Lawrence 67
Roxbury 65
Boardman 64
Santa Clara 62
Sannicandro di Bari 58
Helsinki 56
Ho Chi Minh City 55
Brooklyn 50
Princeton 41
Des Moines 39
Vancouver 38
Munich 36
Tokyo 36
Hanoi 35
Toronto 35
Abidjan 34
Phoenix 32
Buffalo 31
London 31
Chicago 29
Denver 29
San Francisco 29
Brussels 28
Frankfurt am Main 25
Inglewood 25
Warsaw 25
North Bergen 24
Atlanta 23
Hebei 23
Turin 22
Jakarta 21
Catania 20
Falkenstein 20
Montreal 20
Shanghai 20
Orem 19
Brno 18
Dearborn 18
Dublin 18
Jiaxing 18
San Diego 17
Naples 16
Shenyang 16
Turku 16
Nanchang 15
Stockholm 15
Baghdad 14
Bern 14
Bitonto 14
Chennai 14
Pune 14
Taranto 14
Florence 13
Moscow 13
Rio de Janeiro 13
Tashkent 13
Washington 13
Amsterdam 12
Belo Horizonte 12
Boston 12
Columbia 12
New Delhi 12
Nuremberg 12
Philadelphia 12
Laval 11
Mumbai 11
Newton 11
Augusta 10
Guayaquil 10
Haiphong 10
Managua 10
Manchester 10
Memphis 10
Totale 8.336
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Nome #
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 305
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 272
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 260
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 220
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 220
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 212
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 212
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 211
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 207
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 207
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 203
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 199
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 195
Novel hClpP protease activators with potential anticancer activity in DIPG patients 193
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 192
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 191
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 187
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 187
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 186
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 186
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 181
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 180
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 173
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 172
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 172
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 171
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 167
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 163
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 160
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 160
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 157
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ(8)-Δ(7) Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity 157
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 155
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 155
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 153
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 151
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 147
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 147
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 145
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 143
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 139
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 138
34. Methyl substitution on the piperidine ring of N-[ -(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma-1 receptor 137
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 136
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 135
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 135
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 134
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 133
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 132
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 129
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 129
Translational Theragnosis of Ovarian Cancer: where do we stand? 128
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 127
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 127
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 126
Three-dimensional structure of human cyclooxygenase (hCOX)-1 125
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 125
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 125
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 124
Three-dimensional structure of human cyclooxygenase (hCOX)-1 123
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 120
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 118
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 115
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 114
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 111
Ovine COX-1 Isoenzyme Bio-production 111
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 110
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 110
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 109
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 107
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 107
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 106
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 106
TARGETING HUMAN MITOCHONDRIAL ClpP AS A NOVEL THERAPEUTIC APPROACH TO H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 106
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 106
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 104
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 103
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 103
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 102
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. 99
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 99
Why PB28 Could Be a Covid 2019 Game Changer? 92
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 91
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 90
Inside circular economy challenges: “green” application to valorise olive mill wastewater 86
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 83
Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy 82
Mitochondrial Protease ClpP: Cancer Marker and Drug Target 81
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 80
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 79
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 79
null 79
Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats 77
Structural simplification of imipridones to speed up the knowledge on the nature of the interactions with the human ClpP, a mitochondrial protease strictly linked to DIPG 77
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 77
Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood–Brain Barrier Obstacle? 76
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 76
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 76
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 76
Dissociazione di effetti farmacologici in composti chirali 68
Totale 13.852
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Categoria #
all - tutte 51.826
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.826
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022554 0 0 0 44 40 68 42 39 47 41 100 133
2022/20231.037 148 121 74 91 137 128 8 118 164 10 22 16
2023/2024549 26 67 23 43 44 87 26 16 103 37 21 56
2024/20251.986 95 30 144 77 92 138 259 179 117 101 248 506
2025/20264.841 547 254 374 503 562 283 535 177 509 438 228 431
2026/20272.286 860 266 476 684 0 0 0 0 0 0 0 0
Totale 14.310