IRIS
FERORELLI, Savina
 Distribuzione geografica
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Continente #
NA - Nord America 4.020
EU - Europa 2.384
AS - Asia 2.338
SA - Sud America 546
AF - Africa 79
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 5
Totale 9.391
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Nazione #
US - Stati Uniti d'America 3.924
SG - Singapore 889
CN - Cina 615
DE - Germania 528
IT - Italia 517
BR - Brasile 473
SE - Svezia 388
RU - Federazione Russa 328
HK - Hong Kong 303
VN - Vietnam 251
GB - Regno Unito 213
UA - Ucraina 108
FI - Finlandia 82
IN - India 59
CA - Canada 56
JP - Giappone 42
CI - Costa d'Avorio 33
ID - Indonesia 32
MX - Messico 31
FR - Francia 30
NL - Olanda 29
BE - Belgio 27
PL - Polonia 27
AR - Argentina 23
BD - Bangladesh 22
CZ - Repubblica Ceca 21
AU - Australia 19
IR - Iran 18
CH - Svizzera 16
IE - Irlanda 16
IQ - Iraq 16
ES - Italia 15
AT - Austria 13
EC - Ecuador 13
TR - Turchia 12
TW - Taiwan 11
ZA - Sudafrica 11
CL - Cile 9
IL - Israele 8
MA - Marocco 8
KR - Corea 7
UZ - Uzbekistan 7
VE - Venezuela 7
AZ - Azerbaigian 6
CO - Colombia 6
KE - Kenya 6
LT - Lituania 6
PE - Perù 6
PK - Pakistan 6
PY - Paraguay 6
SA - Arabia Saudita 5
EG - Egitto 4
GE - Georgia 4
HU - Ungheria 4
JO - Giordania 4
NP - Nepal 4
TN - Tunisia 4
AE - Emirati Arabi Uniti 3
EE - Estonia 3
EU - Europa 3
LB - Libano 3
PH - Filippine 3
TH - Thailandia 3
UY - Uruguay 3
BB - Barbados 2
DZ - Algeria 2
GT - Guatemala 2
JM - Giamaica 2
MY - Malesia 2
NO - Norvegia 2
RO - Romania 2
TZ - Tanzania 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BW - Botswana 1
BY - Bielorussia 1
DK - Danimarca 1
ET - Etiopia 1
GA - Gabon 1
GI - Gibilterra 1
GM - Gambi 1
HR - Croazia 1
KN - Saint Kitts e Nevis 1
KZ - Kazakistan 1
LY - Libia 1
MD - Moldavia 1
ML - Mali 1
MN - Mongolia 1
NG - Nigeria 1
PT - Portogallo 1
QA - Qatar 1
TT - Trinidad e Tobago 1
VI - Stati Uniti Isole Vergini 1
ZW - Zimbabwe 1
Totale 9.391
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Città #
Singapore 438
Ashburn 436
Chandler 397
Hong Kong 297
Fairfield 291
Jacksonville 230
Nyköping 228
Beijing 226
Woodbridge 198
Bari 166
Dallas 165
Houston 162
Ann Arbor 156
Dong Ket 126
Cambridge 118
Wilmington 115
Seattle 105
Los Angeles 88
New York 83
Nanjing 69
Lawrence 67
Roxbury 65
Sannicandro di Bari 58
São Paulo 49
Boardman 46
Brooklyn 46
Ho Chi Minh City 45
Des Moines 39
Princeton 39
Munich 35
Abidjan 33
Tokyo 30
Hanoi 28
Milan 28
Brussels 26
Inglewood 25
Council Bluffs 24
Santa Clara 24
Warsaw 24
Denver 23
Hebei 23
San Francisco 23
London 22
Toronto 21
Jakarta 20
Brno 18
Buffalo 18
Dearborn 18
Jiaxing 18
Chicago 16
San Diego 16
Shanghai 16
Shenyang 16
Turku 16
Catania 15
Dublin 15
Stockholm 15
Montreal 14
Nanchang 14
Bitonto 13
Moscow 13
Pune 13
Rio de Janeiro 13
Rome 13
Belo Horizonte 12
Boston 12
North Bergen 12
Nuremberg 12
Atlanta 11
Chennai 11
Helsinki 11
Orem 11
Poplar 11
Turin 11
Augusta 10
Frankfurt am Main 9
Guangzhou 9
Johannesburg 9
Phoenix 9
Romola 9
The Dalles 9
Tianjin 9
Wuhan 9
Amsterdam 8
Ardabil 8
Falkenstein 8
Haiphong 8
Leawood 8
Manchester 8
Mumbai 8
San Mateo 8
Taipei 8
Waltham 8
West Lafayette 8
Baghdad 7
Bern 7
Burlington 7
Düsseldorf 7
Florence 7
Hefei 7
Totale 5.573
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Nome #
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 210
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review 201
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity 189
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents 186
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers 174
1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 and sigma-2 receptor ligand: a review 172
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity 165
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity 163
Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier 163
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6) 160
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment 158
Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs) 157
2-Aminopyridine derivatives as potential sigma2 receptor antagonists 155
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer 146
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection 140
Investigation of sigma receptors agonist/antagonist activity through N-(6-methoxytetralin-1-yl)- and N-(6-methoxynaphthalen-1-yl)alkyl derivatives of polymethylpiperidines 139
TRITIUM RADIOLABELING OF [3H]-1-CYCLOHEXYL-4-[3-(5-METHOXY-1,2, 3,4,-TETRAHYDRONAPHTHALEN-1-YL)-N-PROPYL]PIPERAZINE ([3H]-PB28), AS A POTENT SIGMA-2 RECEPTOR LIGAND 138
8-methoxy and p- dimethoxy-1-aminoethylethero-tetralines: synthesis and DA,5HT receptors affinities 137
Novel Derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Improved Fluorescent and σ Receptors Binding Properties 132
"Tritium radiolabeling of [3H]-1-cicloesil-4-[3-(5-methoxy-1,2, 3,4,-tetraidronaftalen-1-il)-n-propil] piperazine ([3H]-PB28)as potent sigma-2 receptor ligand 131
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 131
Microfluidic pervaporation of ethanol from radiopharmaceutical formulations 129
Novel Metal Chelators Thiosemicarbazones with Activity at the sigma2 Receptors and P-glycoprotein: an Innovative Strategy for Resistant Tumors Treatment 128
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies 127
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) 122
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ(8)-Δ(7) Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity 121
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 120
Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma1 receptor 118
Chiral a-substituted a-aryloxy acetic acids: synthesis, absolute configuration, chemical resolution and direct separation by HPLC 117
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 114
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 113
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 112
Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as sigma-1 receptor ligands 112
Tritium radiolabeling of [3H]-1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-n-propyl]piperazine ([3H]-PB28), as a potent sigma-2 receptor ligand 111
Tritium radiolabeling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization 106
Exploring the binding at sigma-1 receptor subtype: newly prepared heterocyclic omega-(1-alkyl)-derivatives of 3,3-dimethylpiperidine 105
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 104
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites 101
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders 100
Novel 4-(-4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as delta8-delta7 sterol isomerase ( Emopamil Binding Protein) selective ligands with antiprolifative activity 100
High-affinity sigma-1 (σ1) receptor ligands based on the σ1 antagonist PB212 99
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior 98
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 97
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 92
34. Methyl substitution on the piperidine ring of N-[ -(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma-1 receptor 92
NOVEL BISPHOSPHONATES, WITH ANTIRESORPTIVE EFFECT IN BONE MINERALIZATION AND OSTEOCLASTOGENESIS, AS MOIETIES OF RA 223-BASED RADIOTRACERS 91
New potential Sigma Ligands for P.E.T.: Isosteric changes on PB28 alkyl chain 90
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT 88
Synthesis of Rigid Dopamine Congeners/ cis and trans 2-(p-methoxyphenyl)-3-methyl morpholine 88
Candida Cylindracea lipase-mediated kinetic resolution of a-substituted a-aryloxyacetic acid methyl esters 88
Direct resolution of a-monoalkyl-a-aryloxyacetic acids via ester or imide derivatives 87
Candida Cylindracea Lipase-mediated kinetic resolution of alpha-substituted alpha-aryloxy acetic acid methyl esters 87
Diffuse Intrinsic Pontine Glioma (DIPG): breakthrough and clinical perspective 86
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer 85
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes 83
null 79
Kinetic resolution of alpha-substituted alpha-aryloxyacetic acid methyl esters by Candida cylindracea lipasi 78
Risoluzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 78
Differentbehavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate 78
Kinetic Resolution Of α-Substituted-α-Aryloxyacetic Acid Methyl Esters By Candida cylindracea Lipase 76
Translational Theragnosis of Ovarian Cancer: where do we stand? 75
Patient Bone Marrow Aspiration to Explore the Cyclooxygenases (COXs) Involvement in Multiple Myeloma 74
Three-dimensional structure of human cyclooxygenase (hCOX)-1 74
Why PB28 Could Be a Covid 2019 Game Changer? 69
Ovine COX-1 Isoenzyme Bio-production 69
DECONSTRUCTING ONC201 TO DESIGN NEW MITOCHONDRIAL ClpP ACTIVATORS FOR PEDIATRIC H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 69
Neuroinflammation and Microglial Constitutive COX-1 Inhibition 66
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment 65
RACEMIZZAZIONE DI COMPOSTI AVENTI UN GRUPPO CARBOSSILICO ADIACENTE AL CENTRO CHIRALE. 65
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery 64
Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma 63
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER 63
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer 62
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 61
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition 61
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG 60
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes 59
Modificazioni della cute umana per trattamento topico con ac.glicolico ad alta concentrazione in tempi diversi 58
CHIROPTICAL AND PHARMACOLOGICAL PROPERTIES OF ALPHA-SUBSTITUTED ALPHA-ARYLOXY ACETIC ACIDS DERIVATIVES. 58
HPLC DIRECT RESOLUTION OF RACEMIC ALPHA-ARYLOXY CARBOXYLIC ACIDS ON DACH-DNB STATIONARY PHASE. 57
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 57
INVERSIONE DI SELETTIVITA' DELL'AZIONE FARMACOLOGICA DI ISOMERI OTTICI STRUTTURALMENTE CORRELATI. 56
Structure-activity relationships of piperazine-2-one derivatives as novel human ClpP activators 55
Repurposing of natural origin compounds as HsClpP inducers to treat diffuse midline glioma (DMG) 54
Effect of newly synthesized rigid clofibric acid derivatives on chloride channel conductance of rat skeletal muscle 54
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity 54
Riduzione Cinetica Catalizzata da Lipasi di Analoghi Rigidi dell’Acido Clofibrico 53
Inside circular economy challenges: “green” application to valorise olive mill wastewater 52
The chiroptical properties of Lactams: 5-substituted-3-Morpholinones 52
TARGETING HUMAN MITOCHONDRIAL ClpP AS A NOVEL THERAPEUTIC APPROACH TO H3K27-ALTERED DIFFUSE MIDLINE GLIOMA 48
Modificazione della cute umana dopo trattamento con geli acquosi di acido tartarico 48
STRUCTURAL EVOLUTION OF ONC201-DERIVED COMPOUNDS TARGETING THE MITOCHONDRIAL PROTEASE CLPP FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA H3K27-ALTERED" 47
Dissociazione di effetti farmacologici in composti chirali 46
Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy 45
Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges 43
null 42
EFFECTS OF CHIRAL CARBOXYLIC ACIDS ON IONIC CHANNELS OF SKELETAL MUSCLE MEMBRANE. 40
Mitochondrial Protease ClpP: Cancer Marker and Drug Target 36
Can Focused Ultrasound Overcome the Failure of Chemotherapy in Treating Pediatric Diffuse Intrinsic Pontine Glioma Due to a Blood–Brain Barrier Obstacle? 35
Structural simplification of imipridones to speed up the knowledge on the nature of the interactions with the human ClpP, a mitochondrial protease strictly linked to DIPG 35
Totale 9.491
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Categoria #
all - tutte 39.134
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.134
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021543 0 0 0 0 0 55 51 28 76 87 89 157
2021/2022673 26 88 5 44 40 68 42 39 47 41 100 133
2022/20231.037 148 121 74 91 137 128 8 118 164 10 22 16
2023/2024549 26 67 23 43 44 87 26 16 103 37 21 56
2024/20251.986 95 30 144 77 92 138 259 179 117 101 248 506
2025/20262.488 547 254 374 503 568 242 0 0 0 0 0 0
Totale 9.671