IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 16.482
AS - Asia 5.764
EU - Europa 5.062
SA - Sud America 1.411
AF - Africa 288
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 8
Totale 29.035
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Nazione #
US - Stati Uniti d'America 16.301
SG - Singapore 2.251
CN - Cina 1.417
RU - Federazione Russa 1.170
BR - Brasile 1.092
SE - Svezia 782
IT - Italia 774
HK - Hong Kong 715
DE - Germania 469
UA - Ucraina 451
VN - Vietnam 430
FR - Francia 381
FI - Finlandia 366
GB - Regno Unito 314
IN - India 210
BD - Bangladesh 121
CI - Costa d'Avorio 106
AR - Argentina 93
ID - Indonesia 91
IQ - Iraq 76
CA - Canada 72
MX - Messico 69
JP - Giappone 61
TR - Turchia 60
CO - Colombia 58
PK - Pakistan 55
IE - Irlanda 54
ZA - Sudafrica 54
NL - Olanda 51
VE - Venezuela 47
PL - Polonia 44
BE - Belgio 41
ES - Italia 41
SA - Arabia Saudita 36
EC - Ecuador 33
MY - Malesia 32
UZ - Uzbekistan 32
CL - Cile 29
IR - Iran 22
MA - Marocco 22
PH - Filippine 22
TN - Tunisia 19
AU - Australia 18
LT - Lituania 18
PE - Perù 18
EG - Egitto 17
UY - Uruguay 17
ET - Etiopia 16
KE - Kenya 15
IL - Israele 14
JO - Giordania 14
AE - Emirati Arabi Uniti 12
AT - Austria 12
DZ - Algeria 12
KR - Corea 12
PY - Paraguay 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
AZ - Azerbaigian 10
RS - Serbia 10
CH - Svizzera 9
PT - Portogallo 9
RO - Romania 9
DK - Danimarca 8
KG - Kirghizistan 8
LV - Lettonia 7
NP - Nepal 7
OM - Oman 7
DO - Repubblica Dominicana 6
GE - Georgia 6
JM - Giamaica 6
KZ - Kazakistan 6
LB - Libano 6
TT - Trinidad e Tobago 6
EE - Estonia 5
EU - Europa 5
HU - Ungheria 5
NG - Nigeria 5
PA - Panama 5
PS - Palestinian Territory 5
SN - Senegal 5
CR - Costa Rica 4
HN - Honduras 4
KH - Cambogia 4
KW - Kuwait 4
TH - Thailandia 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
BG - Bulgaria 3
GT - Guatemala 3
HR - Croazia 3
LU - Lussemburgo 3
MU - Mauritius 3
QA - Qatar 3
SY - Repubblica araba siriana 3
XK - ???statistics.table.value.countryCode.XK??? 3
BH - Bahrain 2
BY - Bielorussia 2
CY - Cipro 2
Totale 29.007
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Città #
Dallas 2.647
Fairfield 1.425
Ashburn 1.283
Singapore 1.160
Chandler 1.092
Jacksonville 991
Woodbridge 971
Houston 803
San Jose 711
Hong Kong 704
Seattle 553
Nyköping 536
Cambridge 516
Wilmington 499
Ann Arbor 423
Beijing 317
Lawrence 262
Bari 260
Roxbury 260
New York 242
Nanjing 227
Lauterbourg 224
Los Angeles 206
Dong Ket 168
Boardman 165
Des Moines 164
Princeton 151
Helsinki 110
Abidjan 105
Brooklyn 104
Ho Chi Minh City 97
São Paulo 95
San Diego 90
Santa Clara 79
Munich 72
Council Bluffs 71
Nanchang 67
Buffalo 64
Jiaxing 64
Hebei 61
Shenyang 61
Inglewood 59
Hanoi 57
Tokyo 52
Rome 51
Dublin 50
London 44
Moscow 44
Tianjin 43
Jakarta 41
Dearborn 40
Brussels 39
Rio de Janeiro 39
Warsaw 39
Chicago 38
Redwood City 35
Frankfurt am Main 32
Orem 32
North Bergen 31
Pune 31
Baghdad 30
Guangzhou 30
Milan 30
Chennai 29
Marseille 29
Paris 29
Falls Church 28
Amsterdam 27
Atlanta 27
Denver 27
San Francisco 26
Turku 26
Tashkent 25
Johannesburg 24
Shanghai 24
Belo Horizonte 23
Brasília 23
Changsha 23
Medellín 23
Phoenix 23
Stockholm 23
Leawood 22
Dhaka 21
Mumbai 21
Jinan 20
Montreal 20
San Mateo 20
Lahore 19
Porto Alegre 18
Wuhan 18
Toronto 17
Ankara 16
Falkenstein 16
Poplar 16
Boston 15
Hefei 15
Kuala Lumpur 15
Manchester 15
Washington 15
Addis Ababa 14
Totale 19.779
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 1.117
1,3-Benzothiazoles as Antimicrobial Agents 1.091
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 999
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 740
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 228
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 225
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 218
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 215
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 214
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 201
2-Aminobenzothiazole derivatives: Search for new antifungal agents 199
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 199
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 196
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 184
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 183
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 180
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 180
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 180
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 178
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 173
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 172
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 170
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 165
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 164
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 163
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 161
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 160
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 160
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 160
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 159
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 156
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 156
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 155
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 154
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 153
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 153
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 149
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 148
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 146
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 146
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 146
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 144
Chemical composition and antibacterial activity of seven uncommon essential oils 143
Facile entry to (-)-R- and (+)-(S)-mexiletine 142
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 140
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 139
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 138
The practice of medicinal chemistry 137
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 136
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 135
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 132
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 131
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 128
Dry powder formulations from olive oil wastewater with high nutraceutical properties 128
Pharmacological differences between R(-) and S(+) Tocainide 127
Organofluorinecontaining anti-infective agents 127
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 126
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 126
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 126
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 124
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 123
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 123
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 122
Novel insights in health-promoting properties of sweet cherries 122
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 122
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 122
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 120
Pharmacological differences between R(-) and S(+) Tocainide 120
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 120
Extra virgin olive oil extracts modulate the inflammatory ability of murine dendritic cells based on their polyphenols pattern: Correlation between chemical composition and biological function 120
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 119
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 118
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 117
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 117
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 115
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 115
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 115
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 115
Toxicological profiles of chemicals in soil 114
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 113
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 113
Lubeluzole: from anti-ischemic to chemosensitizing agent 113
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 112
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 112
An Introduction to Medicinal Chemistry 111
Olive Tree in Circular Economy as a Source of Secondary Metabolites Active for Human and Animal Health Beyond Oxidative Stress and Inflammation 110
Analoghi chirali della Tocainide: attività analgesica centrale 109
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 109
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 108
Stereospecific synthesis and absolute configuration of Mexiletine 108
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 108
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 107
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 107
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 107
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 107
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 106
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 106
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs 106
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 105
Newly synthesized mexiletine and tocainide analogues are potent use-dependent blockers of skeletal muscle sodium channels: potential implication for antimyotonic activity 105
Totale 17.466
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Categoria #
all - tutte 111.509
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 111.509
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021880 0 0 0 0 0 0 0 0 0 355 225 300
2021/20222.000 95 341 22 70 85 129 134 82 140 128 291 483
2022/20233.008 494 280 164 276 399 415 32 297 494 27 56 74
2023/20241.162 94 191 51 90 57 264 38 65 39 50 89 134
2024/20253.893 139 84 392 154 82 296 269 359 209 193 546 1.170
2025/202610.261 1.116 778 2.543 973 842 517 1.022 248 1.508 714 0 0
Totale 29.657