IRIS
FRANCHINI, Carlo
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 19.418
EU - Europa 6.257
AS - Asia 5.918
SA - Sud America 1.498
Continente sconosciuto - Info sul continente non disponibili 653
AF - Africa 301
OC - Oceania 20
Totale 34.065
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 18.983
SG - Singapore 2.269
IT - Italia 1.883
CN - Cina 1.449
RU - Federazione Russa 1.196
BR - Brasile 1.145
SE - Svezia 781
HK - Hong Kong 733
DE - Germania 482
UA - Ucraina 455
VN - Vietnam 435
FR - Francia 388
FI - Finlandia 366
GB - Regno Unito 334
IN - India 210
CA - Canada 182
BD - Bangladesh 162
CI - Costa d'Avorio 106
AR - Argentina 101
ID - Indonesia 97
IQ - Iraq 77
MX - Messico 77
CO - Colombia 68
JP - Giappone 61
TR - Turchia 60
PK - Pakistan 56
IE - Irlanda 55
ZA - Sudafrica 54
NL - Olanda 52
VE - Venezuela 51
PL - Polonia 46
BE - Belgio 43
EC - Ecuador 43
ES - Italia 42
SA - Arabia Saudita 38
MY - Malesia 33
UZ - Uzbekistan 32
CL - Cile 29
IL - Israele 29
PH - Filippine 26
TT - Trinidad e Tobago 24
IR - Iran 22
MA - Marocco 22
HN - Honduras 21
JM - Giamaica 20
LT - Lituania 20
PE - Perù 19
TN - Tunisia 19
AU - Australia 18
CR - Costa Rica 18
EG - Egitto 18
GT - Guatemala 18
UY - Uruguay 18
ET - Etiopia 16
KE - Kenya 16
NI - Nicaragua 15
SV - El Salvador 15
JO - Giordania 14
CW - ???statistics.table.value.countryCode.CW??? 13
KR - Corea 13
PR - Porto Rico 13
AE - Emirati Arabi Uniti 12
AT - Austria 12
DZ - Algeria 12
GP - Guadalupe 12
PY - Paraguay 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
SC - Seychelles 11
TH - Thailandia 11
AZ - Azerbaigian 10
CH - Svizzera 10
RO - Romania 10
RS - Serbia 10
PT - Portogallo 9
DK - Danimarca 8
KG - Kirghizistan 8
GE - Georgia 7
LV - Lettonia 7
NP - Nepal 7
OM - Oman 7
DO - Repubblica Dominicana 6
EE - Estonia 6
HU - Ungheria 6
KZ - Kazakistan 6
LB - Libano 6
PA - Panama 6
EU - Europa 5
NG - Nigeria 5
PS - Palestinian Territory 5
SN - Senegal 5
BG - Bulgaria 4
HR - Croazia 4
KH - Cambogia 4
KW - Kuwait 4
MD - Moldavia 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
LU - Lussemburgo 3
Totale 33.386
Salva come PNG Salva come JPEG
Città #
Dallas 2.674
Ashburn 1.889
Fairfield 1.425
Singapore 1.168
San Jose 1.138
Chandler 1.085
Jacksonville 994
Woodbridge 971
Houston 807
Hong Kong 718
Milan 617
Seattle 554
Nyköping 534
Cambridge 516
Wilmington 499
Ann Arbor 423
Council Bluffs 346
Beijing 329
New York 288
Bari 269
Lawrence 261
Roxbury 260
Rome 254
Los Angeles 246
Nanjing 227
Lauterbourg 224
Boardman 188
Dong Ket 168
Des Moines 165
Princeton 151
Santa Clara 151
São Paulo 135
Washington 125
Brooklyn 110
Helsinki 110
Abidjan 105
Ho Chi Minh City 101
San Diego 90
Munich 72
Buffalo 68
Nanchang 67
Jiaxing 64
Chicago 61
Columbus 61
Hebei 61
Shenyang 61
Inglewood 59
Hanoi 58
Tokyo 52
Dublin 50
London 50
North Bergen 49
Atlanta 48
Toronto 47
Moscow 44
Figino 43
Tianjin 43
Phoenix 42
Jakarta 41
Dearborn 40
Montreal 40
Rio de Janeiro 40
Warsaw 40
Brussels 39
Denver 35
Redwood City 35
Frankfurt am Main 33
Orem 33
San Francisco 33
Pune 31
Baghdad 30
Guangzhou 30
Paris 30
Turin 30
Chennai 29
Falls Church 28
Marseille 28
Amsterdam 27
Shanghai 26
Turku 26
Brasília 25
Tashkent 25
Belo Horizonte 24
Changsha 24
Johannesburg 24
Naples 24
Medellín 23
Stockholm 23
Dhaka 22
Leawood 22
Jinan 20
Mumbai 20
San Mateo 20
Wuhan 19
Lahore 18
Porto Alegre 18
Palermo 17
Ankara 16
Bogotá 16
Boston 16
Totale 22.555
Salva come PNG Salva come JPEG
Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 1.144
1,3-Benzothiazoles as Antimicrobial Agents 1.121
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 1.058
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 755
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 285
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 255
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 247
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 235
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 234
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 218
2-Aminobenzothiazole derivatives: Search for new antifungal agents 216
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 211
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 211
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 210
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 207
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 200
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 197
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 197
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 197
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 194
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 194
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 192
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 188
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 186
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 186
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 185
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 183
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 182
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 179
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 178
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 174
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 174
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 173
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 173
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 172
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 171
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 170
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 169
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 169
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 168
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 167
Facile entry to (-)-R- and (+)-(S)-mexiletine 166
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 166
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 162
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 161
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 160
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 158
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 157
Chemical composition and antibacterial activity of seven uncommon essential oils 154
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 152
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 151
The practice of medicinal chemistry 149
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 148
Novel insights in health-promoting properties of sweet cherries 145
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 145
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 144
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 143
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 143
Dry powder formulations from olive oil wastewater with high nutraceutical properties 143
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 143
Lubeluzole: from anti-ischemic to chemosensitizing agent 142
Pharmacological differences between R(-) and S(+) Tocainide 141
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 141
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 141
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 140
Analoghi chirali della Tocainide: attività analgesica centrale 139
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 138
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 138
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 138
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 137
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 135
Absolute configuration of cyclic amino compounds 135
Pharmacological differences between R(-) and S(+) Tocainide 134
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 134
Extra virgin olive oil extracts modulate the inflammatory ability of murine dendritic cells based on their polyphenols pattern: Correlation between chemical composition and biological function 134
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 132
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 132
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 132
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 131
Organofluorinecontaining anti-infective agents 131
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 130
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 129
An Introduction to Medicinal Chemistry 129
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 128
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 128
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 127
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 127
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 127
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 126
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 125
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 125
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 125
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 124
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 124
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 124
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 124
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 123
Toxicological profiles of chemicals in soil 123
Stereospecific synthesis and absolute configuration of Mexiletine 122
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 121
Totale 19.451
Salva come PNG Salva come JPEG
Categoria #
all - tutte 129.519
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 129.519
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.472 0 0 0 0 85 129 134 82 140 128 291 483
2022/20232.992 493 278 163 276 397 412 32 294 490 27 56 74
2023/20241.157 94 188 51 90 57 264 38 65 39 50 89 132
2024/20253.880 137 84 391 154 81 296 268 359 209 192 543 1.166
2025/202611.751 1.111 776 2.542 970 835 516 1.018 248 1.501 822 311 1.101
2026/20272.952 253 438 883 1.351 27 0 0 0 0 0 0 0
Totale 34.065