IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 10.876
EU - Europa 2.836
AS - Asia 1.329
SA - Sud America 16
OC - Oceania 10
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.079
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Nazione #
US - Stati Uniti d'America 10.857
CN - Cina 1.027
SE - Svezia 765
IT - Italia 609
UA - Ucraina 435
DE - Germania 340
FI - Finlandia 240
GB - Regno Unito 192
VN - Vietnam 173
FR - Francia 96
IE - Irlanda 46
IN - India 44
BE - Belgio 35
SG - Singapore 20
NL - Olanda 16
CA - Canada 15
ID - Indonesia 15
IR - Iran 15
RU - Federazione Russa 10
AU - Australia 9
CZ - Repubblica Ceca 9
JP - Giappone 9
CH - Svizzera 8
BR - Brasile 7
PT - Portogallo 7
KR - Corea 6
LV - Lettonia 6
CL - Cile 5
ES - Italia 5
EU - Europa 5
HK - Hong Kong 5
PL - Polonia 4
RO - Romania 4
DK - Danimarca 3
MX - Messico 3
TR - Turchia 3
ZA - Sudafrica 3
DZ - Algeria 2
EG - Egitto 2
IL - Israele 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
AR - Argentina 1
BD - Bangladesh 1
BG - Bulgaria 1
CO - Colombia 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
KH - Cambogia 1
LU - Lussemburgo 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PK - Pakistan 1
VE - Venezuela 1
Totale 15.079
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Città #
Fairfield 1.425
Chandler 1.098
Jacksonville 990
Woodbridge 971
Houston 794
Ashburn 706
Nyköping 543
Seattle 539
Cambridge 516
Wilmington 497
Ann Arbor 423
Lawrence 264
Roxbury 260
Bari 245
Nanjing 227
New York 174
Dong Ket 168
Des Moines 160
Beijing 153
Princeton 153
Boardman 137
San Diego 87
Brooklyn 73
Nanchang 67
Jiaxing 64
Hebei 61
Shenyang 61
Inglewood 59
Los Angeles 55
Dublin 44
Tianjin 42
Dearborn 40
Redwood City 35
Brussels 34
Rome 33
Guangzhou 30
Falls Church 28
Pune 28
Marseille 27
Paris 25
London 23
Leawood 22
Changsha 20
Jinan 20
San Mateo 19
Shanghai 18
Wuhan 16
Hefei 15
Ardabil 14
Kansas City 13
Milan 13
Norwalk 13
Singapore 13
Helsinki 12
Munich 12
Taizhou 12
Washington 12
West Jordan 12
Auburn Hills 11
Zhengzhou 11
Augusta 10
Grafing 10
Toronto 10
Brno 9
Ningbo 9
Shenzhen 9
Wuxi 9
Bitonto 8
Kilburn 8
Hangzhou 7
Kunming 7
San Francisco 7
Grumo Appula 6
Indiana 6
Palermo 6
Sobreda 6
St Albans 6
Brescia 5
Florence 5
Hanoi 5
Islington 5
Madrid 5
Monmouth Junction 5
Mumbai 5
Napoli 5
Qingdao 5
Tappahannock 5
Bologna 4
Boydton 4
Cedar Knolls 4
Chicago 4
Chongqing 4
Frankfurt am Main 4
Prescot 4
Quanzhou 4
Redmond 4
Riga 4
Tokyo 4
Adelfia 3
Baotou 3
Totale 11.870
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 234
1,3-Benzothiazoles as Antimicrobial Agents 223
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 164
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 150
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 129
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 128
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 127
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 120
2-Aminobenzothiazole derivatives: Search for new antifungal agents 119
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 119
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 115
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 114
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 108
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 108
Chemical composition and antibacterial activity of seven uncommon essential oils 107
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 106
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 105
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 104
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 104
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 104
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 102
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 101
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 101
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 100
Facile entry to (-)-R- and (+)-(S)-mexiletine 98
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 98
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 98
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 97
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 96
Organofluorinecontaining anti-infective agents 96
Pharmacological differences between R(-) and S(+) Tocainide 94
The practice of medicinal chemistry 93
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 93
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 93
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 92
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 92
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 92
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 91
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 91
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 90
null 90
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 90
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 88
Pharmacological differences between R(-) and S(+) Tocainide 87
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 87
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 87
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 86
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 85
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 84
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 84
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 84
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 83
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 82
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 82
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 81
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 81
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 80
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 80
Stereospecific synthesis and absolute configuration of Mexiletine 79
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 79
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 78
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 78
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 77
Synthesis of new phenylpyridyl scaffolds using the Garlanding approach 77
null 77
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 77
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 76
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 76
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 76
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 76
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 75
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 75
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 75
Stereospecific effects of tocainide and its chiral derivatives on rat skeletal muscle sodium channel. 75
null 75
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 74
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 74
Tocainide analogues binding to human serum albumin: a HPLAC and circular dichroism study 73
null 73
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 73
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 73
Antimyotonic actions of new chiral sodium channel blockers 71
Antimyotonic effects of enantiomers of mexiletine-like drugs 71
Lubeluzole: from anti-ischemic to chemosensitizing agent 71
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 70
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 70
null 69
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 68
null 68
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 68
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 67
Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs 67
Contribution to the study of 2-aryloxy-1-phenyl- and 2-aryloxy-2-phenylethanols. Differentiation by mass spectrometry 66
Molecular insights into the local anesthetic receptor within voltage-gated sodium channels using hydroxylated analogs of mexiletine 66
null 65
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 64
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 63
Stereoselectivity in central analgesic action of Tocainide and its analogs 63
Analoghi chirali della Tocainide: attività analgesica centrale 63
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 63
Totale 9.031
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Categoria #
all - tutte 62.193
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.193
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.594 692 242 113 292 364 209 362 259 425 189 372 75
2020/20212.768 401 105 251 132 271 115 211 135 267 355 225 300
2021/20222.000 95 341 22 70 85 129 134 82 140 128 291 483
2022/20233.029 498 283 166 278 401 418 32 300 496 27 56 74
2023/20241.169 94 192 51 91 57 268 38 65 39 51 89 134
2024/2025114 114 0 0 0 0 0 0 0 0 0 0 0
Totale 15.645