IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 11.194
EU - Europa 3.498
AS - Asia 2.012
SA - Sud America 210
AF - Africa 20
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 5
Totale 16.949
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Nazione #
US - Stati Uniti d'America 11.160
CN - Cina 1.063
SE - Svezia 765
IT - Italia 671
SG - Singapore 583
RU - Federazione Russa 495
UA - Ucraina 438
DE - Germania 375
FI - Finlandia 258
GB - Regno Unito 203
BR - Brasile 176
VN - Vietnam 173
FR - Francia 97
IE - Irlanda 48
ID - Indonesia 46
IN - India 46
BE - Belgio 37
NL - Olanda 29
HK - Hong Kong 23
CA - Canada 21
IR - Iran 20
JP - Giappone 13
MX - Messico 11
AU - Australia 9
CH - Svizzera 9
CZ - Repubblica Ceca 9
AR - Argentina 7
AT - Austria 7
LV - Lettonia 7
PT - Portogallo 7
RO - Romania 7
TR - Turchia 7
CL - Cile 6
KR - Corea 6
LT - Lituania 6
PE - Perù 6
ES - Italia 5
EU - Europa 5
PK - Pakistan 5
RS - Serbia 5
ZA - Sudafrica 5
CO - Colombia 4
DZ - Algeria 4
PL - Polonia 4
DK - Danimarca 3
EC - Ecuador 3
EE - Estonia 3
EG - Egitto 3
HU - Ungheria 3
IL - Israele 3
IQ - Iraq 3
LU - Lussemburgo 3
NG - Nigeria 3
UY - Uruguay 3
UZ - Uzbekistan 3
VE - Venezuela 3
BD - Bangladesh 2
KG - Kirghizistan 2
MA - Marocco 2
OM - Oman 2
PS - Palestinian Territory 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
AL - Albania 1
AM - Armenia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BO - Bolivia 1
CI - Costa d'Avorio 1
GE - Georgia 1
GT - Guatemala 1
HR - Croazia 1
KH - Cambogia 1
MD - Moldavia 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PH - Filippine 1
PY - Paraguay 1
SN - Senegal 1
TN - Tunisia 1
Totale 16.949
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Città #
Fairfield 1.425
Chandler 1.098
Jacksonville 990
Woodbridge 971
Houston 794
Ashburn 723
Nyköping 543
Seattle 540
Cambridge 516
Wilmington 497
Ann Arbor 423
Singapore 324
Lawrence 264
Roxbury 260
Bari 252
Nanjing 227
New York 174
Dong Ket 168
Boardman 166
Des Moines 160
Beijing 153
Princeton 153
San Diego 87
Los Angeles 76
Brooklyn 73
Nanchang 67
Jiaxing 64
Hebei 61
Shenyang 61
Inglewood 59
Dublin 46
Moscow 42
Santa Clara 42
Tianjin 42
Dearborn 40
Brussels 36
Rome 36
Redwood City 35
Jakarta 31
North Bergen 31
Guangzhou 30
Munich 30
London 29
Falls Church 28
Helsinki 28
Pune 28
Marseille 27
Paris 25
Milan 24
Changsha 23
Leawood 22
Jinan 20
Shanghai 20
San Mateo 19
Wuhan 16
Hefei 15
Hong Kong 15
São Paulo 15
Ardabil 14
Council Bluffs 14
Toronto 14
Kansas City 13
Norwalk 13
Taizhou 12
Washington 12
West Jordan 12
Zhengzhou 12
Auburn Hills 11
Amsterdam 10
Augusta 10
Grafing 10
Shenzhen 10
Brno 9
Frankfurt am Main 9
Hangzhou 9
Ningbo 9
Nuremberg 9
Wuxi 9
Bitonto 8
Kilburn 8
Kunming 7
Rio de Janeiro 7
San Francisco 7
Tokyo 7
Florence 6
Grumo Appula 6
Indiana 6
Mumbai 6
Palermo 6
Sobreda 6
St Albans 6
Brescia 5
Hanoi 5
Islington 5
Lima 5
Madrid 5
Mexico City 5
Monmouth Junction 5
Naples 5
Napoli 5
Totale 12.516
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 265
1,3-Benzothiazoles as Antimicrobial Agents 249
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 194
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 159
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 145
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 143
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 140
2-Aminobenzothiazole derivatives: Search for new antifungal agents 138
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 138
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 130
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 125
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 122
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 122
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 122
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 118
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 117
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 116
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 115
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 114
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 114
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 114
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 113
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 113
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 112
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 112
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 110
Chemical composition and antibacterial activity of seven uncommon essential oils 110
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 109
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 107
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 106
Facile entry to (-)-R- and (+)-(S)-mexiletine 105
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 105
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 104
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 103
The practice of medicinal chemistry 101
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 101
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 101
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 100
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 100
Pharmacological differences between R(-) and S(+) Tocainide 99
Organofluorinecontaining anti-infective agents 99
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 99
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 96
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 94
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 94
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 93
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 93
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 92
Pharmacological differences between R(-) and S(+) Tocainide 91
null 91
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 91
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 91
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 90
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 90
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 89
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 87
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 87
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 87
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 86
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 85
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 85
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 85
Stereospecific synthesis and absolute configuration of Mexiletine 83
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 83
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 82
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 82
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 82
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 82
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 81
Synthesis of new phenylpyridyl scaffolds using the Garlanding approach 81
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 80
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 80
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 80
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 79
Tocainide analogues binding to human serum albumin: a HPLAC and circular dichroism study 79
Stereospecific effects of tocainide and its chiral derivatives on rat skeletal muscle sodium channel. 78
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 78
null 78
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 78
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 78
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 77
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 76
Antimyotonic actions of new chiral sodium channel blockers 76
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 76
null 76
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 75
Lubeluzole: from anti-ischemic to chemosensitizing agent 75
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 75
Antimyotonic effects of enantiomers of mexiletine-like drugs 74
null 73
Analoghi chirali della Tocainide: attività analgesica centrale 72
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 72
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 72
Studio delle proprietà chirottiche di 2,4-dinitrofenil derivati di ammino composti aventi interesse farmaceutico 70
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 70
Contribution to the study of 2-aryloxy-1-phenyl- and 2-aryloxy-2-phenylethanols. Differentiation by mass spectrometry 70
null 70
Molecular insights into the local anesthetic receptor within voltage-gated sodium channels using hydroxylated analogs of mexiletine 70
Toxicological profiles of chemicals in soil 70
Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs 69
Totale 9.908
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Categoria #
all - tutte 78.256
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 78.256
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020636 0 0 0 0 0 0 0 0 0 189 372 75
2020/20212.768 401 105 251 132 271 115 211 135 267 355 225 300
2021/20222.000 95 341 22 70 85 129 134 82 140 128 291 483
2022/20233.029 498 283 166 278 401 418 32 300 496 27 56 74
2023/20241.169 94 192 51 91 57 268 38 65 39 51 89 134
2024/20252.040 140 85 394 154 83 298 274 362 210 40 0 0
Totale 17.571