IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 17.033
EU - Europa 6.100
AS - Asia 5.838
SA - Sud America 1.422
AF - Africa 288
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 8
Totale 30.709
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Nazione #
US - Stati Uniti d'America 16.811
SG - Singapore 2.266
IT - Italia 1.800
CN - Cina 1.437
RU - Federazione Russa 1.169
BR - Brasile 1.095
SE - Svezia 780
HK - Hong Kong 730
DE - Germania 469
UA - Ucraina 452
VN - Vietnam 431
FR - Francia 385
FI - Finlandia 366
GB - Regno Unito 318
IN - India 209
BD - Bangladesh 143
CI - Costa d'Avorio 106
AR - Argentina 96
CA - Canada 94
ID - Indonesia 92
IQ - Iraq 77
MX - Messico 71
JP - Giappone 61
CO - Colombia 60
TR - Turchia 60
IE - Irlanda 54
PK - Pakistan 54
ZA - Sudafrica 54
NL - Olanda 50
VE - Venezuela 49
PL - Polonia 45
BE - Belgio 42
ES - Italia 41
SA - Arabia Saudita 36
EC - Ecuador 33
MY - Malesia 33
UZ - Uzbekistan 32
CL - Cile 29
IR - Iran 22
MA - Marocco 22
PH - Filippine 22
PE - Perù 19
TN - Tunisia 19
AU - Australia 18
EG - Egitto 18
LT - Lituania 18
UY - Uruguay 17
ET - Etiopia 16
KE - Kenya 15
IL - Israele 14
JO - Giordania 14
AE - Emirati Arabi Uniti 12
AT - Austria 12
DZ - Algeria 12
KR - Corea 12
PY - Paraguay 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
JM - Giamaica 11
AZ - Azerbaigian 10
CH - Svizzera 10
RS - Serbia 10
PT - Portogallo 9
RO - Romania 9
DK - Danimarca 8
KG - Kirghizistan 8
HN - Honduras 7
LV - Lettonia 7
NP - Nepal 7
OM - Oman 7
CR - Costa Rica 6
DO - Repubblica Dominicana 6
GE - Georgia 6
HU - Ungheria 6
KZ - Kazakistan 6
LB - Libano 6
TT - Trinidad e Tobago 6
EE - Estonia 5
EU - Europa 5
NG - Nigeria 5
PA - Panama 5
PS - Palestinian Territory 5
SN - Senegal 5
BG - Bulgaria 4
KH - Cambogia 4
KW - Kuwait 4
MD - Moldavia 4
NI - Nicaragua 4
TH - Thailandia 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
GT - Guatemala 3
HR - Croazia 3
LU - Lussemburgo 3
QA - Qatar 3
SY - Repubblica araba siriana 3
XK - ???statistics.table.value.countryCode.XK??? 3
BH - Bahrain 2
BY - Bielorussia 2
Totale 30.676
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Città #
Dallas 2.658
Fairfield 1.425
Ashburn 1.335
Singapore 1.168
Chandler 1.085
Jacksonville 993
Woodbridge 971
San Jose 820
Houston 804
Hong Kong 716
Milan 608
Seattle 553
Nyköping 534
Cambridge 516
Wilmington 499
Ann Arbor 423
Beijing 323
Bari 268
New York 262
Lawrence 261
Roxbury 260
Rome 246
Nanjing 227
Lauterbourg 224
Los Angeles 213
Boardman 182
Dong Ket 168
Des Moines 164
Princeton 151
Helsinki 110
Santa Clara 110
Brooklyn 106
Abidjan 105
Ho Chi Minh City 98
São Paulo 95
San Diego 90
Council Bluffs 74
Munich 72
Nanchang 67
Buffalo 64
Jiaxing 64
Hebei 61
Shenyang 61
Columbus 60
Inglewood 59
Hanoi 57
Tokyo 52
Dublin 50
London 46
Moscow 44
Figino 43
Tianjin 43
Chicago 41
Jakarta 41
Dearborn 40
Rio de Janeiro 40
Warsaw 40
Brussels 39
Atlanta 36
Redwood City 35
North Bergen 34
Orem 33
Frankfurt am Main 32
Pune 31
Baghdad 30
Denver 30
Guangzhou 30
Paris 30
Chennai 29
Falls Church 28
Marseille 28
Amsterdam 27
Montreal 27
Turin 27
San Francisco 26
Shanghai 26
Turku 26
Phoenix 25
Tashkent 25
Changsha 24
Johannesburg 24
Belo Horizonte 23
Brasília 23
Medellín 23
Stockholm 23
Leawood 22
Dhaka 21
Jinan 20
Mumbai 20
San Mateo 20
Toronto 19
Wuhan 19
Lahore 18
Naples 18
Porto Alegre 18
Ankara 16
Falkenstein 16
Poplar 16
Boston 15
Hefei 15
Totale 20.957
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 1.127
1,3-Benzothiazoles as Antimicrobial Agents 1.106
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 1.032
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 748
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 246
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 237
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 229
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 225
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 219
2-Aminobenzothiazole derivatives: Search for new antifungal agents 210
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 204
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 202
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 202
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 197
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 197
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 190
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 188
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 183
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 183
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 178
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 177
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 175
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 174
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 174
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 174
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 173
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 172
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 171
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 168
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 167
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 164
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 163
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 162
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 161
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 159
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 159
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 158
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 158
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 157
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 155
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 154
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 153
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 152
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 151
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 148
Chemical composition and antibacterial activity of seven uncommon essential oils 145
Facile entry to (-)-R- and (+)-(S)-mexiletine 144
The practice of medicinal chemistry 143
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 143
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 141
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 138
Dry powder formulations from olive oil wastewater with high nutraceutical properties 136
Pharmacological differences between R(-) and S(+) Tocainide 135
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 135
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 134
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 134
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 133
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 132
Novel insights in health-promoting properties of sweet cherries 132
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 131
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 131
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 130
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 128
Organofluorinecontaining anti-infective agents 128
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 128
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 127
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 127
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 127
Extra virgin olive oil extracts modulate the inflammatory ability of murine dendritic cells based on their polyphenols pattern: Correlation between chemical composition and biological function 127
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 126
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 124
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 124
Pharmacological differences between R(-) and S(+) Tocainide 123
An Introduction to Medicinal Chemistry 122
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 121
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 121
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 121
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 121
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 121
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 120
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 119
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 118
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 117
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 116
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 116
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 116
Toxicological profiles of chemicals in soil 116
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 115
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 115
Olive Tree in Circular Economy as a Source of Secondary Metabolites Active for Human and Animal Health Beyond Oxidative Stress and Inflammation 115
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 114
Analoghi chirali della Tocainide: attività analgesica centrale 114
Lubeluzole: from anti-ischemic to chemosensitizing agent 114
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 113
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 113
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 113
Stereospecific synthesis and absolute configuration of Mexiletine 113
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 112
Synthesis, anticancer and antioxidant properties of new indole and pyranoindole derivatives 112
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 111
Totale 18.227
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Categoria #
all - tutte 120.117
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 120.117
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.000 95 341 22 70 85 129 134 82 140 128 291 483
2022/20232.992 493 278 163 276 397 412 32 294 490 27 56 74
2023/20241.157 94 188 51 90 57 264 38 65 39 50 89 132
2024/20253.880 137 84 391 154 81 296 268 359 209 192 543 1.166
2025/202611.751 1.111 776 2.542 970 835 516 1.018 248 1.501 822 311 1.101
2026/2027228 228 0 0 0 0 0 0 0 0 0 0 0
Totale 31.341