IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 16.810
AS - Asia 5.803
EU - Europa 5.085
SA - Sud America 1.410
AF - Africa 288
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 8
Totale 29.424
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Nazione #
US - Stati Uniti d'America 16.611
SG - Singapore 2.263
CN - Cina 1.431
RU - Federazione Russa 1.169
BR - Brasile 1.091
IT - Italia 797
SE - Svezia 780
HK - Hong Kong 725
DE - Germania 469
UA - Ucraina 451
VN - Vietnam 430
FR - Francia 380
FI - Finlandia 366
GB - Regno Unito 317
IN - India 209
BD - Bangladesh 124
CI - Costa d'Avorio 106
AR - Argentina 93
ID - Indonesia 91
CA - Canada 87
IQ - Iraq 77
MX - Messico 71
JP - Giappone 61
TR - Turchia 60
CO - Colombia 58
IE - Irlanda 54
PK - Pakistan 54
ZA - Sudafrica 54
NL - Olanda 50
VE - Venezuela 47
PL - Polonia 44
BE - Belgio 41
ES - Italia 40
SA - Arabia Saudita 36
EC - Ecuador 33
MY - Malesia 33
UZ - Uzbekistan 32
CL - Cile 29
IR - Iran 22
MA - Marocco 22
PH - Filippine 22
TN - Tunisia 19
AU - Australia 18
EG - Egitto 18
LT - Lituania 18
PE - Perù 18
UY - Uruguay 17
ET - Etiopia 16
KE - Kenya 15
IL - Israele 14
JO - Giordania 14
AE - Emirati Arabi Uniti 12
AT - Austria 12
DZ - Algeria 12
KR - Corea 12
PY - Paraguay 12
BO - Bolivia 11
CZ - Repubblica Ceca 11
AZ - Azerbaigian 10
CH - Svizzera 10
RS - Serbia 10
PT - Portogallo 9
RO - Romania 9
DK - Danimarca 8
KG - Kirghizistan 8
JM - Giamaica 7
LV - Lettonia 7
NP - Nepal 7
OM - Oman 7
DO - Repubblica Dominicana 6
GE - Georgia 6
KZ - Kazakistan 6
LB - Libano 6
TT - Trinidad e Tobago 6
EE - Estonia 5
EU - Europa 5
HU - Ungheria 5
NG - Nigeria 5
PA - Panama 5
PS - Palestinian Territory 5
SN - Senegal 5
CR - Costa Rica 4
HN - Honduras 4
KH - Cambogia 4
KW - Kuwait 4
MD - Moldavia 4
TH - Thailandia 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
BG - Bulgaria 3
GT - Guatemala 3
HR - Croazia 3
LU - Lussemburgo 3
QA - Qatar 3
SY - Repubblica araba siriana 3
XK - ???statistics.table.value.countryCode.XK??? 3
BH - Bahrain 2
BY - Bielorussia 2
CY - Cipro 2
Totale 29.396
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Città #
Dallas 2.656
Fairfield 1.425
Ashburn 1.309
Singapore 1.167
Chandler 1.085
Jacksonville 992
Woodbridge 971
San Jose 808
Houston 804
Hong Kong 714
Seattle 553
Nyköping 534
Cambridge 516
Wilmington 499
Ann Arbor 423
Beijing 321
Lawrence 261
New York 261
Bari 260
Roxbury 260
Nanjing 227
Lauterbourg 224
Los Angeles 209
Boardman 182
Dong Ket 168
Des Moines 164
Princeton 151
Helsinki 110
Brooklyn 106
Abidjan 105
Ho Chi Minh City 97
São Paulo 95
San Diego 90
Santa Clara 87
Munich 72
Council Bluffs 71
Nanchang 67
Jiaxing 64
Buffalo 63
Hebei 61
Shenyang 61
Inglewood 59
Hanoi 57
Rome 53
Tokyo 52
Dublin 50
London 45
Moscow 44
Tianjin 43
Jakarta 41
Dearborn 40
Brussels 39
Chicago 39
Rio de Janeiro 39
Warsaw 39
Redwood City 35
Atlanta 34
Frankfurt am Main 32
Milan 32
Orem 32
North Bergen 31
Pune 31
Baghdad 30
Guangzhou 30
Chennai 29
Denver 29
Paris 29
Falls Church 28
Marseille 28
Amsterdam 27
Montreal 27
San Francisco 26
Turku 26
Shanghai 25
Tashkent 25
Changsha 24
Johannesburg 24
Phoenix 24
Belo Horizonte 23
Brasília 23
Medellín 23
Stockholm 23
Leawood 22
Dhaka 21
Jinan 20
Mumbai 20
San Mateo 20
Toronto 19
Wuhan 19
Lahore 18
Porto Alegre 18
Ankara 16
Falkenstein 16
Poplar 16
Boston 15
Hefei 15
Kansas City 15
Kuala Lumpur 15
Manchester 15
Mexico City 15
Totale 19.998
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 1.120
1,3-Benzothiazoles as Antimicrobial Agents 1.094
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 1.001
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 742
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 230
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 229
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 220
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 220
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 217
2-Aminobenzothiazole derivatives: Search for new antifungal agents 205
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 203
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 200
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 197
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 189
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 187
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 182
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 182
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 181
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 180
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 175
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 172
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 171
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 169
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 167
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 167
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 165
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 164
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 163
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 162
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 162
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 159
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 157
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 157
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 156
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 155
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 154
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 152
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 152
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 151
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 148
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 146
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 145
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 144
Chemical composition and antibacterial activity of seven uncommon essential oils 144
Facile entry to (-)-R- and (+)-(S)-mexiletine 143
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 143
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 143
The practice of medicinal chemistry 138
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 138
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 136
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 136
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 132
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 130
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 129
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 129
Organofluorinecontaining anti-infective agents 128
Dry powder formulations from olive oil wastewater with high nutraceutical properties 128
Pharmacological differences between R(-) and S(+) Tocainide 127
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 127
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 127
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 127
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 127
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 126
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 126
Novel insights in health-promoting properties of sweet cherries 124
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 123
Pharmacological differences between R(-) and S(+) Tocainide 122
Extra virgin olive oil extracts modulate the inflammatory ability of murine dendritic cells based on their polyphenols pattern: Correlation between chemical composition and biological function 122
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 120
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 120
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 120
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 120
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 119
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 119
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 119
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 117
An Introduction to Medicinal Chemistry 117
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 117
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 116
Toxicological profiles of chemicals in soil 116
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 115
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 114
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 114
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 114
Lubeluzole: from anti-ischemic to chemosensitizing agent 114
Olive Tree in Circular Economy as a Source of Secondary Metabolites Active for Human and Animal Health Beyond Oxidative Stress and Inflammation 113
Analoghi chirali della Tocainide: attività analgesica centrale 112
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 112
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 111
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 110
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 108
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 108
Stereospecific synthesis and absolute configuration of Mexiletine 108
N-(2,6-Xylil) piperazine and piperidine carboxamides as new antimyotonic agents 108
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 108
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs 108
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 107
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 107
Newly synthesized mexiletine and tocainide analogues are potent use-dependent blockers of skeletal muscle sodium channels: potential implication for antimyotonic activity 107
Candida Cylindracea Lipase-Mediated Kinetic Resolution Of α-Substituted-α-Ariloxyacetic Acid Methyl Esters 107
Totale 17.692
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Categoria #
all - tutte 115.547
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 115.547
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021300 0 0 0 0 0 0 0 0 0 0 0 300
2021/20222.000 95 341 22 70 85 129 134 82 140 128 291 483
2022/20232.992 493 278 163 276 397 412 32 294 490 27 56 74
2023/20241.157 94 188 51 90 57 264 38 65 39 50 89 132
2024/20253.880 137 84 391 154 81 296 268 359 209 192 543 1.166
2025/202610.694 1.111 776 2.542 970 835 516 1.018 248 1.501 822 311 44
Totale 30.056