IRIS
FRANCHINI, Carlo
 Distribuzione geografica
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Continente #
NA - Nord America 10.923
EU - Europa 2.826
AS - Asia 1.093
SA - Sud America 15
OC - Oceania 10
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 5
Totale 14.879
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Nazione #
US - Stati Uniti d'America 10.904
CN - Cina 812
SE - Svezia 770
IT - Italia 594
UA - Ucraina 438
DE - Germania 341
FI - Finlandia 241
GB - Regno Unito 193
VN - Vietnam 173
FR - Francia 95
IE - Irlanda 46
IN - India 44
BE - Belgio 35
CA - Canada 15
IR - Iran 15
NL - Olanda 15
ID - Indonesia 13
RU - Federazione Russa 10
AU - Australia 9
JP - Giappone 9
CH - Svizzera 8
BR - Brasile 7
PT - Portogallo 7
KR - Corea 6
LV - Lettonia 6
CZ - Repubblica Ceca 5
ES - Italia 5
EU - Europa 5
HK - Hong Kong 5
CL - Cile 4
PL - Polonia 4
RO - Romania 4
DK - Danimarca 3
MX - Messico 3
TR - Turchia 3
ZA - Sudafrica 3
DZ - Algeria 2
EG - Egitto 2
IL - Israele 2
RS - Serbia 2
SG - Singapore 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
AR - Argentina 1
BD - Bangladesh 1
BG - Bulgaria 1
CO - Colombia 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
KH - Cambogia 1
LU - Lussemburgo 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
VE - Venezuela 1
Totale 14.879
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Città #
Fairfield 1.435
Chandler 1.106
Jacksonville 997
Woodbridge 979
Houston 796
Ashburn 707
Nyköping 544
Seattle 541
Cambridge 519
Wilmington 499
Ann Arbor 434
Lawrence 264
Roxbury 260
Bari 246
Nanjing 228
New York 174
Dong Ket 168
Des Moines 161
Princeton 153
Beijing 140
Boardman 134
San Diego 87
Brooklyn 73
Nanchang 67
Hebei 61
Shenyang 60
Inglewood 59
Jiaxing 56
Los Angeles 55
Dublin 44
Tianjin 42
Dearborn 40
Redwood City 35
Brussels 34
Rome 33
Falls Church 28
Pune 28
Marseille 27
Paris 24
London 23
Leawood 22
Changsha 20
Jinan 20
San Mateo 19
Hefei 15
Ardabil 14
Kansas City 13
Milan 13
Norwalk 13
Helsinki 12
Washington 12
West Jordan 12
Auburn Hills 11
Munich 11
Taizhou 11
Zhengzhou 11
Augusta 10
Grafing 10
Toronto 10
Ningbo 9
Bitonto 8
Guangzhou 8
Kilburn 8
Kunming 7
San Francisco 7
Grumo Appula 6
Hangzhou 6
Indiana 6
Sobreda 6
St Albans 6
Brno 5
Florence 5
Hanoi 5
Islington 5
Madrid 5
Monmouth Junction 5
Mumbai 5
Napoli 5
Tappahannock 5
Bologna 4
Boydton 4
Cedar Knolls 4
Chicago 4
Frankfurt am Main 4
Palermo 4
Prescot 4
Redmond 4
Riga 4
Tokyo 4
Adelfia 3
Baotou 3
Belém 3
Capua 3
Düsseldorf 3
Lucca 3
Malden 3
Mola Di Bari 3
Nagareyama 3
Nuremberg 3
Sannicandro di Bari 3
Totale 11.815
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Nome #
1, 3‐Benzothiazoles as Antimicrobial Agents 220
1,3-Benzothiazoles as Antimicrobial Agents 216
1,3-Benzothiazole derivatives: design, synthesis and evaluation of their antimicrobial activity 155
Bovine and soybean milk bioactive compounds: Effects on inflammatory response of human intestinal Caco-2 cells 148
4H-1,4-benzothiazine, dihydro-1,4-benzothiazinones and 2-amino-5- fluorobenzenethiol derivatives: Design, synthesis and in vitro antimicrobial screening 127
1-Pentanoyl-N-{[2’-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-pyrrolidine-2-carboxamide: Investigation of Structural Variations 126
Comparison Between Different Flavored Olive Oil Production Techniques: Healthy Value and Process Efficiency 125
2-Aminobenzothiazole derivatives: Search for new antifungal agents 118
Effects of sweet cherry polyphenols on enhanced osteoclastogenesis associated with childhood obesity 118
Apixaban: Effective And Safe In Preventing Thromboembolic Events In Patients With Atrial Fibrillation And Renal Failure. 114
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 114
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 113
Chemical composition and antibacterial activity of seven uncommon essential oils 107
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 106
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 105
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 104
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 104
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 103
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives 102
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 102
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 101
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 100
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 99
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 98
Facile entry to (-)-R- and (+)-(S)-mexiletine 97
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 97
In vitro interactions between anidulafungin and nonsteroidal anti-inflammatory drugs on biofilms of Candida spp 97
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 96
Biological evaluation of Hyperforin and its Hydrogenated analogue on bacterial growth and biofilm production 95
Organofluorinecontaining anti-infective agents 95
Pharmacological differences between R(-) and S(+) Tocainide 93
The practice of medicinal chemistry 92
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 92
Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos 92
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 91
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 91
null 90
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 89
POLYPHENO srl - Spin Off Accademica Accreditata del''Università degli Studi di Bari "Aldo Moro" 89
Lipase-mediated kinetic resolution of rigid clofibrate analogues, with lipid-modifying activity 88
1-Peptidyl-2-Haloacetylhydrazines as substrate analogue inhibitors toward Cathepsin B and Calpains 88
Pharmacological differences between R(-) and S(+) Tocainide 87
Synthesis and biological evaluation of 3-alkyloxazolidin-2-ones as reversible MAO inhibitors 87
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 87
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 86
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 84
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 84
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 84
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 83
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 82
Antiproliferative activity evaluation of a series of N-1,3-benzothiazol-2-ylbenzamides as novel apoptosis inducers 82
Derivati morfolinici come analoghi semi rigidi di farmaci adrenergici: sintesi e configurazione assoluta di alchilmorfoline 81
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains 81
AT1 receptor ligands: virtual screening based design with TOPP descriptors, synthesis and biological evaluation of pyrrolidine derivatives 81
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 81
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 80
Stereospecific synthesis and absolute configuration of Mexiletine 79
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 79
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 79
In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment 78
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 77
null 77
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 77
Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase 77
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 76
Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial Activity 76
Synthesis of new phenylpyridyl scaffolds using the Garlanding approach 76
Species-dependent binding of tocainide analogues to albumin: Affinity chromatography and circular dichroism study 76
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 75
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 75
Effect of Methyl -β- Cyclodextrin on the antimicrobial activity of a new series of poorly water-soluble benzothiazoles 75
null 75
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 74
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 74
Stereospecific effects of tocainide and its chiral derivatives on rat skeletal muscle sodium channel. 74
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 73
Tocainide analogues binding to human serum albumin: a HPLAC and circular dichroism study 73
null 73
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 73
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 72
Antimyotonic actions of new chiral sodium channel blockers 71
Antimyotonic effects of enantiomers of mexiletine-like drugs 71
Lubeluzole: from anti-ischemic to chemosensitizing agent 71
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 70
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 70
null 69
Enhanced solubility and antibacterial activity of lipophilic fluoro-substituted N-benzoyl-2-aminobenzothiazoles by complexation with beta-cyclodextrins 69
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 68
null 68
Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs 67
null 66
Molecular insights into the local anesthetic receptor within voltage-gated sodium channels using hydroxylated analogs of mexiletine 66
Contribution to the study of 2-aryloxy-1-phenyl- and 2-aryloxy-2-phenylethanols. Differentiation by mass spectrometry 65
null 65
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 65
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 64
Novel thiation reagent for the selective synthesis of thiopeptides from peptides: "p-Alkoxyphenylthionophosphine sulfide dimers" 63
Stereoselectivity in central analgesic action of Tocainide and its analogs 63
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 62
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 62
Totale 8.895
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Categoria #
all - tutte 58.968
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.968
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019893 0 0 0 0 0 0 0 0 0 0 415 478
2019/20203.616 694 244 114 294 367 210 365 261 428 190 373 76
2020/20212.781 402 106 252 133 272 115 212 136 268 357 226 302
2021/20222.005 95 341 22 70 86 130 134 82 140 130 292 483
2022/20233.044 498 283 166 280 402 423 32 301 502 27 56 74
2023/20241.001 94 195 51 91 57 268 38 65 39 51 52 0
Totale 15.445