IRIS
CONTE, Diana
 Distribuzione geografica
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Continente #
NA - Nord America 16.489
EU - Europa 3.856
AS - Asia 2.352
SA - Sud America 558
AF - Africa 30
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 6
Totale 23.298
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Nazione #
US - Stati Uniti d'America 16.440
CN - Cina 1.277
SE - Svezia 806
SG - Singapore 797
UA - Ucraina 643
RU - Federazione Russa 584
DE - Germania 513
BR - Brasile 507
FI - Finlandia 367
IT - Italia 361
GB - Regno Unito 260
FR - Francia 141
BE - Belgio 74
HK - Hong Kong 51
IN - India 51
IE - Irlanda 37
VN - Vietnam 37
CA - Canada 34
ID - Indonesia 27
IR - Iran 24
NL - Olanda 18
AR - Argentina 16
CZ - Repubblica Ceca 14
JP - Giappone 13
TR - Turchia 13
AT - Austria 11
MX - Messico 10
IQ - Iraq 9
CL - Cile 8
MA - Marocco 8
EC - Ecuador 7
LT - Lituania 7
KR - Corea 6
NP - Nepal 6
UZ - Uzbekistan 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
BD - Bangladesh 5
EG - Egitto 5
EU - Europa 5
UY - Uruguay 5
AU - Australia 4
CO - Colombia 4
KE - Kenya 4
PK - Pakistan 4
PY - Paraguay 4
ZA - Sudafrica 4
AL - Albania 3
CH - Svizzera 3
DK - Danimarca 3
DZ - Algeria 3
JO - Giordania 3
KZ - Kazakistan 3
A1 - Anonimo 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
IL - Israele 2
KW - Kuwait 2
NZ - Nuova Zelanda 2
PA - Panama 2
PH - Filippine 2
RO - Romania 2
SN - Senegal 2
AM - Armenia 1
AZ - Azerbaigian 1
BO - Bolivia 1
CR - Costa Rica 1
EE - Estonia 1
ES - Italia 1
HN - Honduras 1
JM - Giamaica 1
KG - Kirghizistan 1
LB - Libano 1
LV - Lettonia 1
NG - Nigeria 1
NO - Norvegia 1
OM - Oman 1
PT - Portogallo 1
QA - Qatar 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TN - Tunisia 1
TW - Taiwan 1
Totale 23.298
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Città #
Fairfield 2.365
Woodbridge 1.572
Jacksonville 1.391
Ashburn 1.377
Chandler 1.360
Houston 1.125
Seattle 903
Cambridge 872
Wilmington 772
Ann Arbor 726
Nyköping 608
Singapore 422
Lawrence 336
Roxbury 336
Nanjing 334
Princeton 265
Boardman 215
Des Moines 214
Beijing 185
New York 155
Bari 153
Inglewood 139
San Diego 122
Shenyang 90
Nanchang 87
Jiaxing 82
Hebei 74
Brussels 71
Los Angeles 68
London 55
Santa Clara 55
Tianjin 51
Hong Kong 48
Helsinki 45
Dearborn 42
Changsha 40
Falls Church 38
Dublin 37
Dong Ket 36
Guangzhou 29
Moscow 28
Pune 28
São Paulo 28
San Mateo 24
Shanghai 24
Jakarta 23
Jinan 23
Wuhan 23
Brooklyn 22
Council Bluffs 21
Monmouth Junction 21
Norwalk 21
Toronto 20
Paris 18
Ardabil 17
Brasília 17
Zhengzhou 17
Ningbo 16
Redwood City 16
Kunming 15
Rio de Janeiro 15
Brno 14
Augusta 13
Hefei 13
Indiana 13
Tappahannock 13
Leawood 12
Washington 12
Belo Horizonte 10
Kilburn 10
Milan 10
Genova 9
Prescot 9
San Francisco 9
Chiswick 8
Frankfurt am Main 8
Ottawa 8
Curitiba 7
Hounslow 7
Islington 7
Mexico City 7
Montignoso 7
Tokyo 7
Caxias do Sul 6
Chicago 6
Hangzhou 6
Manaus 6
Munich 6
North Bergen 6
Porto Alegre 6
Quanzhou 6
Shenzhen 6
Acton 5
Auburn Hills 5
Baghdad 5
Campinas 5
Falkenstein 5
Fortaleza 5
Jinhua 5
Lauterbourg 5
Totale 17.639
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 416
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 175
ClC-1 chloride channels: state-of-the-art research and future challenges 161
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 152
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine 152
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 150
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 150
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 141
Ion channels in drug discovery and safety pharmacology 138
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission 133
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 133
Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels 131
Activation and inhibition of kidney CLC-K chloride channels by fenamates 129
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 129
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 127
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography 126
Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats 123
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 122
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 120
Acetazolamide opens the muscular KCa2+ channel: a novel mechanism of action that may explain the therapeutic effect of the drug in the hypokalemic periodic paralysis 119
Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies 119
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 119
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 118
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K+-depleted rats 117
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 116
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 115
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 114
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 112
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 112
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 111
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 111
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 111
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 110
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 109
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 107
Redox homeostasis, oxidative stress and disuse muscle atrophy 105
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 105
Acetazolamide opens the muscular K(Ca)2+ channel: A novel mechanism of action that may explain the therapeutic effect of the drug in hypokalemic periodic paralysis 105
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 104
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 103
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 103
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 103
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 102
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 102
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 101
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 101
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 101
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 101
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 101
null 100
Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle 99
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 99
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 98
Hybrid assemblies of ATP-sensitive K+ channels determine their muscle-type-dependent biophysical and pharmacological properties 97
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia 96
Aging and chloride channel regulation in rat fast-twitch muscle fibres 96
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading 96
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 96
EFFETTI DEL DANTROLENE SODICO SUL MUSCOLO DETRUSORE DI VESCICA URINARIA ISOLATA DI CAVIA 95
Changes of chloride channel regulation in rat skeletal muscle during aging 95
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 94
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 94
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 94
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 93
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 93
Taurine and skeletal muscle ion channels 92
Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes 92
null 91
EFFECTS OF VINBLASTINE ON THE COMPONENT CONDUCTANCES OF RAT SKELETAL MUSCLE FIBERS 90
null 90
Involvement of K(Ca2+)channels in the local abnormalities and hyperkalemia following the ischemia-reperfusion injury of rat skeletal muscle 90
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels 89
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 89
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 88
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 88
Involvement of 3Na+/2K+ ATP-ase and Pi-3 kinase in the response of skeletal muscle ATP-sensitive K+ channels to insulin 88
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 88
Enantiomeric effects on excitation-contraction coupling in frog skeletal muscle by a chiral phenoxy carboxylic acid 87
Muscle loading modulates aquaporin-4 expression in skeletal muscle 87
Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium 87
null 87
Effects of Acetazolamide on alpha subunit of human BK channel expressed in HEK293 cells 86
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 86
null 86
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+ - deficient rats 86
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 86
Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block 85
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 85
Developmental changes of membrane electrical properties of rat skeletal muscle fibers produced by prenatal exposure to carbon monoxide 85
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 85
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 83
Molecular determinants of differential pore blocking of kidney CLC-K chloride channels 83
Insulin modulation of ATP-sensitive K+ channel of rat skeletal muscle is impaired in the hypokalaemic state 83
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 83
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 83
Taurine blocks ATP-sensitive potassium channels of rat skeletal muscle fibres interfering with the sulphonylurea receptor 82
Comparative evaluation of the effects of lidocaine (lignocaine) hydrochloride and salicylate on nervous and Purkinje fibres 82
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor 82
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 82
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action 81
Totale 10.717
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Categoria #
all - tutte 110.571
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 110.571
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020600 0 0 0 0 0 0 0 0 0 0 466 134
2020/20213.585 426 272 317 292 319 152 271 179 331 506 305 215
2021/20222.535 89 488 19 158 135 141 145 124 154 153 368 561
2022/20233.778 652 269 224 362 479 526 20 426 636 21 74 89
2023/20241.483 101 254 62 85 109 256 159 287 7 32 14 117
2024/20252.692 144 86 469 144 131 398 323 472 248 252 25 0
Totale 23.864