IRIS
CONTE, Diana
 Distribuzione geografica
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Continente #
NA - Nord America 23.499
AS - Asia 7.709
EU - Europa 6.316
SA - Sud America 2.151
Continente sconosciuto - Info sul continente non disponibili 589
AF - Africa 247
OC - Oceania 12
Totale 40.523
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Nazione #
US - Stati Uniti d'America 22.944
SG - Singapore 3.310
IT - Italia 1.915
CN - Cina 1.841
BR - Brasile 1.731
HK - Hong Kong 937
SE - Svezia 819
UA - Ucraina 667
RU - Federazione Russa 645
DE - Germania 594
FR - Francia 501
FI - Finlandia 458
VN - Vietnam 392
GB - Regno Unito 383
BD - Bangladesh 298
CA - Canada 241
IN - India 233
AR - Argentina 135
ID - Indonesia 89
IQ - Iraq 89
BE - Belgio 77
CO - Colombia 70
EC - Ecuador 67
TR - Turchia 67
MX - Messico 65
ZA - Sudafrica 56
PK - Pakistan 53
JP - Giappone 52
VE - Venezuela 47
SA - Arabia Saudita 45
IE - Irlanda 42
NL - Olanda 40
CR - Costa Rica 37
TT - Trinidad e Tobago 37
CL - Cile 36
ES - Italia 32
MA - Marocco 32
GT - Guatemala 31
UZ - Uzbekistan 31
CI - Costa d'Avorio 29
MY - Malesia 29
PL - Polonia 28
HN - Honduras 27
IR - Iran 25
PH - Filippine 25
KE - Kenya 23
IL - Israele 22
NP - Nepal 22
TN - Tunisia 22
JM - Giamaica 21
LT - Lituania 21
NI - Nicaragua 21
PY - Paraguay 21
AE - Emirati Arabi Uniti 20
SV - El Salvador 20
AT - Austria 19
JO - Giordania 19
EG - Egitto 18
UY - Uruguay 18
GP - Guadalupe 17
KR - Corea 16
CW - ???statistics.table.value.countryCode.CW??? 15
PR - Porto Rico 15
CZ - Repubblica Ceca 14
ET - Etiopia 14
PE - Perù 14
AL - Albania 13
KZ - Kazakistan 12
SC - Seychelles 12
AU - Australia 10
LB - Libano 10
PA - Panama 10
TH - Thailandia 10
DZ - Algeria 9
OM - Oman 9
BO - Bolivia 8
GE - Georgia 8
PS - Palestinian Territory 8
KG - Kirghizistan 7
EE - Estonia 6
SN - Senegal 6
AO - Angola 5
AZ - Azerbaigian 5
EU - Europa 5
NG - Nigeria 5
BH - Bahrain 4
CH - Svizzera 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
GR - Grecia 4
KW - Kuwait 4
RO - Romania 4
RS - Serbia 4
AM - Armenia 3
BB - Barbados 3
BG - Bulgaria 3
BN - Brunei Darussalam 3
DM - Dominica 3
HU - Ungheria 3
NO - Norvegia 3
Totale 39.905
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Città #
Ashburn 2.694
Fairfield 2.365
Singapore 1.782
Woodbridge 1.573
Jacksonville 1.399
San Jose 1.365
Chandler 1.354
Houston 1.145
Hong Kong 932
Seattle 919
Cambridge 873
Milan 815
Wilmington 775
Ann Arbor 726
Nyköping 601
Dallas 558
Council Bluffs 446
Beijing 442
Roxbury 336
Nanjing 335
Lawrence 334
Lauterbourg 305
New York 291
Princeton 264
Rome 234
Los Angeles 227
Boardman 220
Des Moines 217
Santa Clara 191
São Paulo 173
Bari 162
Ho Chi Minh City 147
Inglewood 139
San Diego 124
Helsinki 115
Shenyang 91
Nanchang 87
Buffalo 82
Jiaxing 82
Chicago 74
Hebei 74
London 74
Brussels 73
Columbus 72
Toronto 67
Figino 62
Hanoi 61
Rio de Janeiro 55
Turin 55
Tianjin 51
Brasília 50
Brooklyn 50
San Francisco 47
Atlanta 44
Baghdad 44
Montreal 44
Munich 43
Dearborn 42
Changsha 41
Phoenix 41
Tokyo 41
Washington 40
Falls Church 39
Dublin 38
Belo Horizonte 36
Dong Ket 36
Pune 35
North Bergen 34
Jakarta 33
Naples 33
The Dalles 32
Moscow 31
Guangzhou 29
Shanghai 29
Abidjan 28
Frankfurt am Main 28
Mexico City 28
Wuhan 27
Medellín 26
San José 26
Chennai 25
Denver 25
Dhaka 25
Tashkent 25
Guatemala City 24
Jinan 24
Manchester 24
Norwalk 24
Paris 24
San Mateo 24
Johannesburg 23
Warsaw 23
Bologna 22
Orem 22
Charlotte 21
Monmouth Junction 21
Turku 21
Curitiba 20
Guayaquil 20
Managua 20
Totale 27.190
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 475
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 323
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine 273
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 258
ClC-1 chloride channels: state-of-the-art research and future challenges 234
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 221
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 220
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 219
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 216
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 216
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography 213
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 212
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 210
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 209
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 209
Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels 204
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission 203
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K+-depleted rats 203
Ion channels in drug discovery and safety pharmacology 196
Activation and inhibition of kidney CLC-K chloride channels by fenamates 194
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 194
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 193
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 193
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 185
Acetazolamide opens the muscular KCa2+ channel: a novel mechanism of action that may explain the therapeutic effect of the drug in the hypokalemic periodic paralysis 178
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 176
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 174
Acetazolamide opens the muscular K(Ca)2+ channel: A novel mechanism of action that may explain the therapeutic effect of the drug in hypokalemic periodic paralysis 173
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 173
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 172
Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats 172
Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies 171
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 171
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 170
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 170
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 169
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 169
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 169
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 167
Aging and chloride channel regulation in rat fast-twitch muscle fibres 167
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 166
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 164
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 164
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 160
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 159
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading 155
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 154
Effect of rat hindlimb suspension on cable properties, ionic conductances and fiber type composition of slow-twitch muscle. 153
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 153
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 153
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 152
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 151
Changes of chloride channel regulation in rat skeletal muscle during aging 150
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 149
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+ - deficient rats 149
Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle 148
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 148
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 148
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 148
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia 147
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 147
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 147
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 146
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 146
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 145
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 144
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 144
Effects of Acetazolamide on alpha subunit of human BK channel expressed in HEK293 cells 143
EFFETTI DEL DANTROLENE SODICO SUL MUSCOLO DETRUSORE DI VESCICA URINARIA ISOLATA DI CAVIA 143
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 143
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 143
Antioxidant treatment of hindlimb-unloaded mouse in vivo counteracts fiber type transition but not atrophy of disused skeletal muscles 142
Redox homeostasis, oxidative stress and disuse muscle atrophy 141
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo 141
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 141
Involvement of K(Ca2+)channels in the local abnormalities and hyperkalemia following the ischemia-reperfusion injury of rat skeletal muscle 139
Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle 138
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 137
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 137
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 136
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 136
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 135
Hybrid assemblies of ATP-sensitive K+ channels determine their muscle-type-dependent biophysical and pharmacological properties 135
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 134
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 134
Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes 133
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 133
Bisphosphonates Targeting Ion Channels and Musculoskeletal Effects 132
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels 132
Biophysical changes of skeletal muscle K-ATP channels in K+ depleted rats and pharmacological interventions. 132
Age-dependent effects of disuse on electrophysiogical parameters and calcium homeostasis in the soleus muscle of hindlimb-unloaded mice 132
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 132
EFFECTS OF VINBLASTINE ON THE COMPONENT CONDUCTANCES OF RAT SKELETAL MUSCLE FIBERS 131
Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium 131
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 130
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor 130
Antitumorali 130
Database search of spontaneous reports and pharmacological investigations on the sulfonylureas and glinides-induced atrophy in skeletal muscle 129
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 129
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 128
Totale 16.766
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Categoria #
all - tutte 171.499
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 171.499
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.781 0 0 0 0 135 141 145 124 154 153 368 561
2022/20233.757 648 266 222 360 477 523 20 423 634 21 74 89
2023/20241.476 101 253 62 84 109 252 159 287 7 31 14 117
2024/20254.958 143 85 467 144 130 396 318 469 247 249 732 1.578
2025/202610.739 1.377 485 868 1.078 1.000 552 1.393 312 906 945 359 1.464
2026/20273.682 310 581 862 1.914 15 0 0 0 0 0 0 0
Totale 40.523