IRIS
CONTE, Diana
 Distribuzione geografica
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Continente #
NA - Nord America 21.481
AS - Asia 7.681
EU - Europa 6.144
SA - Sud America 2.087
Continente sconosciuto - Info sul continente non disponibili 574
AF - Africa 236
OC - Oceania 12
Totale 38.215
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Nazione #
US - Stati Uniti d'America 21.184
SG - Singapore 3.308
CN - Cina 1.836
IT - Italia 1.816
BR - Brasile 1.673
HK - Hong Kong 937
SE - Svezia 819
UA - Ucraina 665
RU - Federazione Russa 624
DE - Germania 590
FR - Francia 494
FI - Finlandia 458
VN - Vietnam 391
GB - Regno Unito 365
BD - Bangladesh 297
IN - India 233
CA - Canada 137
AR - Argentina 135
IQ - Iraq 89
ID - Indonesia 87
BE - Belgio 77
CO - Colombia 66
EC - Ecuador 66
TR - Turchia 66
MX - Messico 65
ZA - Sudafrica 56
PK - Pakistan 53
JP - Giappone 51
VE - Venezuela 46
SA - Arabia Saudita 44
IE - Irlanda 41
CL - Cile 36
NL - Olanda 34
MA - Marocco 32
ES - Italia 31
UZ - Uzbekistan 31
CI - Costa d'Avorio 29
MY - Malesia 28
IR - Iran 25
PH - Filippine 25
PL - Polonia 25
KE - Kenya 23
CR - Costa Rica 22
NP - Nepal 22
TN - Tunisia 22
PY - Paraguay 21
AE - Emirati Arabi Uniti 20
JO - Giordania 19
AT - Austria 18
EG - Egitto 18
UY - Uruguay 18
LT - Lituania 17
KR - Corea 16
CZ - Repubblica Ceca 14
ET - Etiopia 14
PE - Perù 14
AL - Albania 13
JM - Giamaica 13
HN - Honduras 12
IL - Israele 12
KZ - Kazakistan 12
TT - Trinidad e Tobago 11
AU - Australia 10
LB - Libano 10
PA - Panama 10
DZ - Algeria 9
OM - Oman 9
TH - Thailandia 9
BO - Bolivia 8
GE - Georgia 8
KG - Kirghizistan 7
PS - Palestinian Territory 7
SN - Senegal 6
AO - Angola 5
AZ - Azerbaigian 5
EU - Europa 5
NG - Nigeria 5
NI - Nicaragua 5
SV - El Salvador 5
BH - Bahrain 4
CH - Svizzera 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
GR - Grecia 4
GT - Guatemala 4
KW - Kuwait 4
RO - Romania 4
RS - Serbia 4
AM - Armenia 3
BG - Bulgaria 3
DM - Dominica 3
HU - Ungheria 3
NO - Norvegia 3
A1 - Anonimo 2
BB - Barbados 2
BN - Brunei Darussalam 2
CG - Congo 2
EE - Estonia 2
LV - Lettonia 2
LY - Libia 2
Totale 37.604
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Città #
Fairfield 2.365
Ashburn 2.025
Singapore 1.782
Woodbridge 1.573
Jacksonville 1.398
Chandler 1.354
Houston 1.141
San Jose 1.076
Hong Kong 932
Seattle 918
Cambridge 872
Milan 794
Wilmington 774
Ann Arbor 726
Nyköping 601
Dallas 551
Beijing 442
Council Bluffs 438
Roxbury 336
Nanjing 335
Lawrence 334
Lauterbourg 305
Princeton 264
New York 246
Rome 223
Boardman 217
Des Moines 216
Los Angeles 202
Bari 162
Santa Clara 161
Ho Chi Minh City 147
Inglewood 139
San Diego 122
São Paulo 119
Helsinki 115
Shenyang 91
Nanchang 87
Jiaxing 82
Buffalo 81
Hebei 74
Brussels 73
London 73
Chicago 71
Columbus 71
Figino 60
Hanoi 60
Rio de Janeiro 54
Tianjin 51
Turin 51
Brasília 48
Brooklyn 47
San Francisco 47
Baghdad 44
Munich 43
Dearborn 42
Changsha 41
Tokyo 41
Phoenix 40
Dublin 38
Falls Church 38
Belo Horizonte 36
Dong Ket 36
Toronto 36
Pune 35
Jakarta 33
Atlanta 32
The Dalles 32
Montreal 31
Moscow 31
Guangzhou 29
Shanghai 29
Abidjan 28
Frankfurt am Main 28
Mexico City 28
Naples 28
Wuhan 27
Chennai 25
Dhaka 25
Medellín 25
Tashkent 25
Jinan 24
Manchester 24
Paris 24
San Mateo 24
Denver 23
Johannesburg 23
Norwalk 23
Warsaw 22
Monmouth Junction 21
Orem 21
Turku 21
Curitiba 20
Guayaquil 20
Stockholm 20
Washington 20
Poplar 19
Porto Alegre 19
Augusta 18
Campinas 18
Charlotte 18
Totale 25.874
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 469
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 290
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine 257
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 252
ClC-1 chloride channels: state-of-the-art research and future challenges 231
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 215
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 212
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 209
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 208
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 207
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 206
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 205
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography 204
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 199
Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels 198
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K+-depleted rats 198
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 192
Activation and inhibition of kidney CLC-K chloride channels by fenamates 190
Ion channels in drug discovery and safety pharmacology 190
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission 189
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 188
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 185
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 185
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 177
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 170
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 169
Acetazolamide opens the muscular KCa2+ channel: a novel mechanism of action that may explain the therapeutic effect of the drug in the hypokalemic periodic paralysis 169
Acetazolamide opens the muscular K(Ca)2+ channel: A novel mechanism of action that may explain the therapeutic effect of the drug in hypokalemic periodic paralysis 168
Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats 167
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 166
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 165
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 165
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 165
Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies 164
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 163
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 161
Aging and chloride channel regulation in rat fast-twitch muscle fibres 161
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 161
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 161
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 159
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 158
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 156
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 156
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 155
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 154
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 150
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading 149
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 148
Changes of chloride channel regulation in rat skeletal muscle during aging 147
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 147
Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle 144
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 144
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+ - deficient rats 144
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 144
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 144
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 142
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 142
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 141
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 140
Antioxidant treatment of hindlimb-unloaded mouse in vivo counteracts fiber type transition but not atrophy of disused skeletal muscles 140
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 139
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 139
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 138
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 138
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 138
Redox homeostasis, oxidative stress and disuse muscle atrophy 137
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 137
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 137
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 136
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 135
Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle 135
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 134
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia 133
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 133
Effects of Acetazolamide on alpha subunit of human BK channel expressed in HEK293 cells 132
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 132
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo 132
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 131
Hybrid assemblies of ATP-sensitive K+ channels determine their muscle-type-dependent biophysical and pharmacological properties 131
Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes 130
Biophysical changes of skeletal muscle K-ATP channels in K+ depleted rats and pharmacological interventions. 129
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 129
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 129
EFFETTI DEL DANTROLENE SODICO SUL MUSCOLO DETRUSORE DI VESCICA URINARIA ISOLATA DI CAVIA 128
Involvement of K(Ca2+)channels in the local abnormalities and hyperkalemia following the ischemia-reperfusion injury of rat skeletal muscle 128
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 128
Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium 128
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 128
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 127
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor 127
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels 126
Database search of spontaneous reports and pharmacological investigations on the sulfonylureas and glinides-induced atrophy in skeletal muscle 126
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 125
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 125
In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: A new drug target for hypertension? 125
EFFECTS OF VINBLASTINE ON THE COMPONENT CONDUCTANCES OF RAT SKELETAL MUSCLE FIBERS 124
Age-dependent effects of disuse on electrophysiogical parameters and calcium homeostasis in the soleus muscle of hindlimb-unloaded mice 124
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 124
Antitumorali 124
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 123
Totale 16.059
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Categoria #
all - tutte 164.047
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 164.047
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.958 0 0 19 158 135 141 145 124 154 153 368 561
2022/20233.757 648 266 222 360 477 523 20 423 634 21 74 89
2023/20241.476 101 253 62 84 109 252 159 287 7 31 14 117
2024/20254.958 143 85 467 144 130 396 318 469 247 249 732 1.578
2025/202610.739 1.377 485 868 1.078 1.000 552 1.393 312 906 945 359 1.464
2026/20271.374 310 581 483 0 0 0 0 0 0 0 0 0
Totale 38.215