IRIS
CONTE, Diana
 Distribuzione geografica
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Continente #
NA - Nord America 19.867
AS - Asia 7.425
EU - Europa 4.728
SA - Sud America 2.050
AF - Africa 233
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 8
Totale 34.323
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Nazione #
US - Stati Uniti d'America 19.642
SG - Singapore 3.271
CN - Cina 1.784
BR - Brasile 1.662
HK - Hong Kong 923
SE - Svezia 819
UA - Ucraina 664
RU - Federazione Russa 624
DE - Germania 589
FR - Francia 491
FI - Finlandia 458
IT - Italia 418
VN - Vietnam 391
GB - Regno Unito 361
IN - India 232
BD - Bangladesh 164
AR - Argentina 132
CA - Canada 106
IQ - Iraq 89
ID - Indonesia 85
BE - Belgio 75
TR - Turchia 65
EC - Ecuador 61
MX - Messico 60
ZA - Sudafrica 56
CO - Colombia 53
PK - Pakistan 52
JP - Giappone 49
SA - Arabia Saudita 44
VE - Venezuela 44
IE - Irlanda 41
CL - Cile 35
NL - Olanda 33
MA - Marocco 32
UZ - Uzbekistan 31
CI - Costa d'Avorio 29
ES - Italia 28
IR - Iran 25
MY - Malesia 25
PL - Polonia 25
PH - Filippine 24
KE - Kenya 23
NP - Nepal 22
TN - Tunisia 22
PY - Paraguay 21
JO - Giordania 19
AE - Emirati Arabi Uniti 18
AT - Austria 18
EG - Egitto 18
LT - Lituania 17
UY - Uruguay 16
CZ - Repubblica Ceca 14
ET - Etiopia 14
KR - Corea 14
PE - Perù 14
AL - Albania 13
IL - Israele 12
KZ - Kazakistan 12
AU - Australia 10
CR - Costa Rica 10
DZ - Algeria 9
JM - Giamaica 9
LB - Libano 9
OM - Oman 9
PA - Panama 9
BO - Bolivia 8
GE - Georgia 8
HN - Honduras 8
TT - Trinidad e Tobago 8
KG - Kirghizistan 7
PS - Palestinian Territory 7
SN - Senegal 6
TH - Thailandia 6
AO - Angola 5
AZ - Azerbaigian 5
EU - Europa 5
NG - Nigeria 5
BH - Bahrain 4
CH - Svizzera 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
GR - Grecia 4
KW - Kuwait 4
RS - Serbia 4
AM - Armenia 3
BG - Bulgaria 3
DM - Dominica 3
HU - Ungheria 3
NI - Nicaragua 3
NO - Norvegia 3
RO - Romania 3
A1 - Anonimo 2
BB - Barbados 2
EE - Estonia 2
LV - Lettonia 2
LY - Libia 2
MN - Mongolia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
Totale 34.289
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Città #
Fairfield 2.365
Ashburn 1.956
Singapore 1.769
Woodbridge 1.573
Jacksonville 1.393
Chandler 1.354
Houston 1.138
Hong Kong 918
Seattle 915
Cambridge 872
San Jose 798
Wilmington 773
Ann Arbor 726
Nyköping 601
Dallas 519
Beijing 416
Roxbury 336
Nanjing 335
Lawrence 334
Lauterbourg 305
Princeton 263
Boardman 215
Des Moines 215
New York 208
Los Angeles 177
Bari 155
Ho Chi Minh City 147
Inglewood 139
San Diego 122
São Paulo 119
Helsinki 115
Santa Clara 99
Shenyang 91
Nanchang 87
Jiaxing 82
Hebei 74
London 72
Brussels 71
Buffalo 70
Council Bluffs 65
Hanoi 60
Rio de Janeiro 53
Chicago 52
Tianjin 51
Brasília 47
Baghdad 44
Brooklyn 44
Munich 43
Dearborn 42
Changsha 41
Tokyo 39
Dublin 38
Falls Church 38
San Francisco 38
Belo Horizonte 36
Dong Ket 36
Pune 35
Jakarta 33
Moscow 31
Toronto 31
Guangzhou 29
Abidjan 28
Montreal 28
Frankfurt am Main 27
The Dalles 27
Wuhan 27
Phoenix 26
Shanghai 26
Atlanta 25
Chennai 25
Columbus 25
Dhaka 25
Tashkent 25
Jinan 24
San Mateo 24
Johannesburg 23
Manchester 23
Medellín 23
Mexico City 23
Paris 23
Norwalk 22
Warsaw 22
Monmouth Junction 21
Turku 21
Curitiba 20
Denver 20
Orem 20
Stockholm 20
Poplar 19
Porto Alegre 19
Campinas 18
Guayaquil 18
Washington 18
Ardabil 17
Milan 17
Zhengzhou 17
Amman 16
Augusta 16
Caxias do Sul 16
Istanbul 16
Totale 23.693
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 457
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine 240
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 234
ClC-1 chloride channels: state-of-the-art research and future challenges 216
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 209
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 203
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 197
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 197
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 191
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 188
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography 188
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 187
Activation and inhibition of kidney CLC-K chloride channels by fenamates 184
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 184
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K+-depleted rats 184
Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels 181
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 181
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 180
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission 179
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 172
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 172
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 172
Ion channels in drug discovery and safety pharmacology 172
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 164
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 163
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 163
Acetazolamide opens the muscular KCa2+ channel: a novel mechanism of action that may explain the therapeutic effect of the drug in the hypokalemic periodic paralysis 160
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 159
Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies 158
Acetazolamide opens the muscular K(Ca)2+ channel: A novel mechanism of action that may explain the therapeutic effect of the drug in hypokalemic periodic paralysis 156
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 155
Aging and chloride channel regulation in rat fast-twitch muscle fibres 154
Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats 154
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 152
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 152
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 151
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 149
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 149
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 148
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 147
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 146
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 145
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 144
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 143
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading 143
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 141
Changes of chloride channel regulation in rat skeletal muscle during aging 140
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 137
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 137
Antioxidant treatment of hindlimb-unloaded mouse in vivo counteracts fiber type transition but not atrophy of disused skeletal muscles 135
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 135
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 135
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 135
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 133
Redox homeostasis, oxidative stress and disuse muscle atrophy 133
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 133
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 133
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 132
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 132
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 132
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+ - deficient rats 132
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 131
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 131
Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle 130
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 130
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 127
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 126
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 126
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 125
Biophysical changes of skeletal muscle K-ATP channels in K+ depleted rats and pharmacological interventions. 125
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 125
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 125
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo 124
Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium 124
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 123
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 123
Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle 123
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor 122
Effects of Acetazolamide on alpha subunit of human BK channel expressed in HEK293 cells 121
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 121
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 121
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 121
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 120
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 120
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 120
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia 119
Involvement of K(Ca2+)channels in the local abnormalities and hyperkalemia following the ischemia-reperfusion injury of rat skeletal muscle 119
Hybrid assemblies of ATP-sensitive K+ channels determine their muscle-type-dependent biophysical and pharmacological properties 119
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 119
Taurine and skeletal muscle ion channels 118
Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes 118
EFFETTI DEL DANTROLENE SODICO SUL MUSCOLO DETRUSORE DI VESCICA URINARIA ISOLATA DI CAVIA 117
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels 117
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 117
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 116
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 116
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 115
Muscle loading modulates aquaporin-4 expression in skeletal muscle 114
Age-dependent effects of disuse on electrophysiogical parameters and calcium homeostasis in the soleus muscle of hindlimb-unloaded mice 114
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle 114
Totale 14.914
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Categoria #
all - tutte 148.010
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 148.010
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.026 0 0 0 0 0 0 0 0 0 506 305 215
2021/20222.535 89 488 19 158 135 141 145 124 154 153 368 561
2022/20233.757 648 266 222 360 477 523 20 423 634 21 74 89
2023/20241.476 101 253 62 84 109 252 159 287 7 31 14 117
2024/20254.958 143 85 467 144 130 396 318 469 247 249 732 1.578
2025/20268.787 1.377 485 868 1.078 1.000 552 1.393 312 906 816 0 0
Totale 34.889