IRIS
CONTE, Diana
 Distribuzione geografica
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Continente #
NA - Nord America 18.525
AS - Asia 5.989
EU - Europa 4.202
SA - Sud America 1.704
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 8
Totale 30.564
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Nazione #
US - Stati Uniti d'America 18.350
SG - Singapore 2.673
CN - Cina 1.626
BR - Brasile 1.487
HK - Hong Kong 879
SE - Svezia 816
UA - Ucraina 659
RU - Federazione Russa 600
DE - Germania 562
FI - Finlandia 389
IT - Italia 385
GB - Regno Unito 344
VN - Vietnam 286
FR - Francia 175
IN - India 119
CA - Canada 89
AR - Argentina 83
BE - Belgio 74
BD - Bangladesh 71
ID - Indonesia 53
MX - Messico 44
IQ - Iraq 43
EC - Ecuador 38
IE - Irlanda 38
JP - Giappone 34
TR - Turchia 31
NL - Olanda 29
ZA - Sudafrica 29
CI - Costa d'Avorio 27
IR - Iran 25
PL - Polonia 23
CO - Colombia 22
ES - Italia 22
VE - Venezuela 19
CL - Cile 18
AT - Austria 17
MA - Marocco 16
PY - Paraguay 16
UZ - Uzbekistan 16
LT - Lituania 15
SA - Arabia Saudita 15
CZ - Repubblica Ceca 14
KE - Kenya 13
KR - Corea 13
PK - Pakistan 13
AE - Emirati Arabi Uniti 12
EG - Egitto 11
UY - Uruguay 11
IL - Israele 10
NP - Nepal 10
AL - Albania 9
JO - Giordania 9
TN - Tunisia 9
KZ - Kazakistan 7
PE - Perù 7
TT - Trinidad e Tobago 7
AU - Australia 6
HN - Honduras 6
JM - Giamaica 6
PA - Panama 6
CR - Costa Rica 5
DZ - Algeria 5
EU - Europa 5
NG - Nigeria 5
SN - Senegal 5
DK - Danimarca 4
DO - Repubblica Dominicana 4
GE - Georgia 4
KG - Kirghizistan 4
KW - Kuwait 4
PH - Filippine 4
AZ - Azerbaigian 3
BG - Bulgaria 3
BO - Bolivia 3
CH - Svizzera 3
DM - Dominica 3
LB - Libano 3
MY - Malesia 3
NO - Norvegia 3
OM - Oman 3
RS - Serbia 3
A1 - Anonimo 2
AM - Armenia 2
AO - Angola 2
BB - Barbados 2
BH - Bahrain 2
EE - Estonia 2
GR - Grecia 2
LV - Lettonia 2
MN - Mongolia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
RO - Romania 2
AF - Afghanistan, Repubblica islamica di 1
BJ - Benin 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CG - Congo 1
Totale 30.548
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Città #
Fairfield 2.365
Ashburn 1.766
Woodbridge 1.573
Jacksonville 1.393
Chandler 1.354
Singapore 1.298
Houston 1.136
Seattle 914
Hong Kong 876
Cambridge 872
Wilmington 772
Ann Arbor 726
Nyköping 601
Dallas 515
Beijing 401
Roxbury 336
Lawrence 334
Nanjing 334
Princeton 263
Boardman 215
Des Moines 214
New York 201
Los Angeles 166
Bari 154
Inglewood 139
San Diego 122
Ho Chi Minh City 111
São Paulo 104
Shenyang 91
Nanchang 87
Santa Clara 85
Jiaxing 82
Hebei 74
Brussels 71
London 70
Buffalo 69
Tianjin 51
Chicago 48
Helsinki 46
Rio de Janeiro 46
Brasília 44
Munich 43
Dearborn 42
Brooklyn 41
Changsha 41
Hanoi 40
Falls Church 38
San Francisco 37
Dong Ket 36
Dublin 36
Belo Horizonte 34
Pune 32
Jakarta 31
Guangzhou 29
Moscow 29
Toronto 29
Council Bluffs 27
The Dalles 27
Tokyo 27
Wuhan 27
Abidjan 26
Columbus 25
Shanghai 25
San Mateo 24
Jinan 23
Norwalk 22
Phoenix 22
Atlanta 21
Monmouth Junction 21
Turku 21
Warsaw 21
Paris 20
Curitiba 19
Johannesburg 19
Manchester 19
Montreal 19
Stockholm 19
Chennai 18
Dhaka 18
Washington 18
Ardabil 17
Denver 17
Poplar 17
Zhengzhou 17
Baghdad 16
Caxias do Sul 16
Frankfurt am Main 16
Kunming 16
Ningbo 16
Porto Alegre 16
Redwood City 16
Augusta 15
Campinas 15
Mexico City 15
Brno 14
Salt Lake City 14
Boston 13
Guayaquil 13
Hefei 13
Indiana 13
Totale 21.490
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 439
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine 216
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 206
ClC-1 chloride channels: state-of-the-art research and future challenges 197
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 192
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 184
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 176
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 175
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 175
In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography 170
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 169
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission 166
Activation and inhibition of kidney CLC-K chloride channels by fenamates 165
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 162
Ion channels in drug discovery and safety pharmacology 162
Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models 161
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 161
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 161
Acetazolamide prevents vacuolar myopathy in skeletal muscle of K+-depleted rats 159
Carbonic anhydrase inhibitors ameliorate the symptoms of hypokalaemic periodic paralysis in rats by opening the muscular Ca2+-activated-K+ channels 158
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 158
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 157
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 153
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 153
Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies 151
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 150
Acetazolamide opens the muscular KCa2+ channel: a novel mechanism of action that may explain the therapeutic effect of the drug in the hypokalemic periodic paralysis 147
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 146
Acetazolamide opens the muscular K(Ca)2+ channel: A novel mechanism of action that may explain the therapeutic effect of the drug in hypokalemic periodic paralysis 144
Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats 144
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 142
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 139
Aging and chloride channel regulation in rat fast-twitch muscle fibres 139
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 137
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 137
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 137
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 137
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 135
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 133
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 133
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 132
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 131
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 130
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 129
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 129
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 126
Analysis by two-dimensional Blue Native/SDS-PAGE of membrane protein alterations in rat soleus muscle after hindlimb unloading 126
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 125
Changes of chloride channel regulation in rat skeletal muscle during aging 124
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 123
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 122
Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle 121
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 121
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 121
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 121
Redox homeostasis, oxidative stress and disuse muscle atrophy 120
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 119
Carbonic anhydrase inhibitors are specific openers of skeletal muscle BK channel of K+ - deficient rats 119
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 118
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 118
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 117
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 115
Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium 115
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 114
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 114
Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle 114
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 113
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 113
Taurine and skeletal muscle ion channels 112
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 112
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 112
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 112
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels 111
Use-Dependent block of voltage-gated sodium channels by orphenadrine through binding at the local anesthetic receptor 111
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 111
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo 110
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 110
Hybrid assemblies of ATP-sensitive K+ channels determine their muscle-type-dependent biophysical and pharmacological properties 110
EFFETTI DEL DANTROLENE SODICO SUL MUSCOLO DETRUSORE DI VESCICA URINARIA ISOLATA DI CAVIA 109
In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia 109
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 109
Involvement of K(Ca2+)channels in the local abnormalities and hyperkalemia following the ischemia-reperfusion injury of rat skeletal muscle 109
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 108
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 108
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 108
Effects of Acetazolamide on alpha subunit of human BK channel expressed in HEK293 cells 107
Muscle loading modulates aquaporin-4 expression in skeletal muscle 107
Dual response of the KATP channels to staurosporine: a novel role of SUR2B, SUR1 and Kir6.2 subunits in the regulation of the atrophy in different skeletal muscle phenotypes 107
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle 107
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 106
EFFECTS OF VINBLASTINE ON THE COMPONENT CONDUCTANCES OF RAT SKELETAL MUSCLE FIBERS 105
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 105
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 105
Database search of spontaneous reports and pharmacological investigations on the sulfonylureas and glinides-induced atrophy in skeletal muscle 105
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 105
Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block 104
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 104
Comparative evaluation of the effects of lidocaine (lignocaine) hydrochloride and salicylate on nervous and Purkinje fibres 103
Antioxidant treatment of hindlimb-unloaded mouse in vivo counteracts fiber type transition but not atrophy of disused skeletal muscles 103
Totale 13.464
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Categoria #
all - tutte 139.756
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 139.756
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.959 0 0 0 0 0 152 271 179 331 506 305 215
2021/20222.535 89 488 19 158 135 141 145 124 154 153 368 561
2022/20233.757 648 266 222 360 477 523 20 423 634 21 74 89
2023/20241.476 101 253 62 84 109 252 159 287 7 31 14 117
2024/20254.958 143 85 467 144 130 396 318 469 247 249 732 1.578
2025/20265.028 1.377 485 868 1.078 1.000 220 0 0 0 0 0 0
Totale 31.130