IRIS
IMBRICI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 7.355
AS - Asia 3.108
EU - Europa 2.680
SA - Sud America 828
Continente sconosciuto - Info sul continente non disponibili 478
AF - Africa 106
OC - Oceania 6
Totale 14.561
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Nazione #
US - Stati Uniti d'America 7.223
SG - Singapore 1.241
IT - Italia 1.031
BR - Brasile 674
CN - Cina 626
HK - Hong Kong 380
SE - Svezia 311
DE - Germania 294
RU - Federazione Russa 264
VN - Vietnam 230
FR - Francia 190
BD - Bangladesh 173
FI - Finlandia 148
GB - Regno Unito 142
UA - Ucraina 136
IN - India 111
ID - Indonesia 71
AR - Argentina 56
CA - Canada 53
MX - Messico 43
TR - Turchia 38
NL - Olanda 34
IQ - Iraq 32
BE - Belgio 29
PK - Pakistan 27
ZA - Sudafrica 26
SA - Arabia Saudita 25
EC - Ecuador 24
JP - Giappone 23
PL - Polonia 21
CO - Colombia 17
MA - Marocco 17
TN - Tunisia 17
VE - Venezuela 16
AT - Austria 15
ES - Italia 15
PH - Filippine 14
UZ - Uzbekistan 14
CL - Cile 13
PY - Paraguay 12
AE - Emirati Arabi Uniti 11
MY - Malesia 11
NP - Nepal 11
CR - Costa Rica 10
EG - Egitto 9
CI - Costa d'Avorio 8
IE - Irlanda 8
KZ - Kazakistan 8
JO - Giordania 7
KE - Kenya 7
BO - Bolivia 6
CZ - Repubblica Ceca 6
DZ - Algeria 6
OM - Oman 6
TW - Taiwan 6
AU - Australia 5
LB - Libano 5
PE - Perù 5
PS - Palestinian Territory 5
PT - Portogallo 5
TH - Thailandia 5
AL - Albania 4
CH - Svizzera 4
ET - Etiopia 4
IL - Israele 4
KR - Corea 4
RS - Serbia 4
DK - Danimarca 3
GE - Georgia 3
GT - Guatemala 3
HN - Honduras 3
KG - Kirghizistan 3
LV - Lettonia 3
SC - Seychelles 3
UY - Uruguay 3
AZ - Azerbaigian 2
BB - Barbados 2
BH - Bahrain 2
DM - Dominica 2
DO - Repubblica Dominicana 2
HR - Croazia 2
IR - Iran 2
JM - Giamaica 2
LT - Lituania 2
PR - Porto Rico 2
RO - Romania 2
SN - Senegal 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BT - Bhutan 1
BY - Bielorussia 1
BZ - Belize 1
Totale 14.065
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Città #
Fairfield 738
Ashburn 661
Singapore 611
Woodbridge 608
San Jose 528
Houston 456
Chandler 431
Hong Kong 375
Milan 328
Jacksonville 320
Seattle 281
Cambridge 269
Nyköping 257
Ann Arbor 208
Wilmington 208
Council Bluffs 203
Beijing 189
Bari 134
Lauterbourg 127
Rome 126
Dallas 120
Lawrence 102
Roxbury 99
Los Angeles 97
New York 94
Nanjing 89
Inglewood 81
Des Moines 70
Ho Chi Minh City 63
Columbus 62
Santa Clara 58
Boardman 55
Jakarta 53
Helsinki 52
Buffalo 45
Hanoi 43
São Paulo 43
Figino 41
San Diego 35
London 34
Princeton 32
Falkenstein 31
Chicago 29
Moscow 29
Brooklyn 28
Dong Ket 28
Nanchang 27
Brussels 25
Hebei 25
Munich 25
Shenyang 25
Paris 23
Tokyo 22
Pune 21
Chennai 20
Rio de Janeiro 20
Naples 19
Denver 17
Mexico City 17
Warsaw 17
Brasília 16
Frankfurt am Main 16
Jiaxing 16
Johannesburg 16
Montreal 16
Nuremberg 16
Turku 16
The Dalles 15
Atlanta 14
Baghdad 14
Jeddah 14
Washington 14
Dhaka 13
Toronto 13
Ankara 12
Guangzhou 12
Phoenix 12
Tashkent 12
Tianjin 12
Turin 12
Haiphong 11
Taranto 11
Belo Horizonte 10
Boston 10
Curitiba 10
Dearborn 10
Guayaquil 10
Orem 10
Salvador 10
Stockholm 10
Vienna 10
Changsha 9
Florence 9
Genoa 9
Norwalk 9
Poplar 9
San Francisco 9
San José 9
Shanghai 9
Tunis 9
Totale 9.348
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Nome #
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 289
ATP Sensitive Potassium Channels in the Skeletal Muscle Function: Involvement of the KCNJ11(Kir6.2) Gene in the Determination of Mechanical Warner Bratzer Shear Force 231
ClC-1 chloride channels: state-of-the-art research and future challenges 228
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 215
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 212
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 207
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 205
ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation 195
Characterization of Student Drinking Behaviors at the Beginning of the First Academic Year at One University in Southern Italy 191
Ion channels in drug discovery and safety pharmacology 189
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 185
Kidney CLC-K Chloride Channels Show Differential Pharmacological Profiles Depending on the Heterologous Expression System 175
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 169
Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita 168
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 164
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 164
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 160
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 152
pH Dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia 150
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 150
Andersen-Tawil syndrome: New potassium channel mutations and possible phenotypic variation 148
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature 146
A Novel KCNA1 Mutation Identified in an Italian Family Affected by Episodic Ataxia Type 1. 140
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia 139
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 139
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 137
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 137
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 132
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders 131
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 129
Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene 128
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia—authors’ response 127
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability 127
A novel kcna2 variant in a patient with non-progressive congenital ataxia and epilepsy: Functional characterization and sensitivity to 4-aminopyridine 124
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 123
Autism with seizure and intellectual disability: possible causative role of gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1 122
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 121
Late-onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A 121
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy 121
Kidney CLC-K chloride channels inhibitors: structure-based studies and efficacy in hypertension and associated CLC-K polymorphisms. 120
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 119
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 118
The Kir5.1 Potassium Channel is an Important Determinant of Neuronal PCO2/pH Sensitivity. 118
Functional Study of Novel Bartter's Syndrome Mutations in ClC-Kb and Rescue by the Accessory Subunit Barttin Toward Personalized Medicine 118
Ion channels gene expression analysis in myotonia congenita patients carrying ClC-1 chloride channel mutations 117
Kv1.1 channelopathies: Pathophysiological mechanisms and therapeutic approaches 117
All atom molecular dynamics simulation of the K+ Channel Chimera Kv1.2/2.1 116
Episodic Ataxias as Ion Channel Diseases. 116
Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1 116
Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy 115
Skeletal muscle ClC-1 chloride channels in health and diseases 115
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvb1 Channel 114
Pathomechanisms of a CLCN1 Mutation Found in a Russian Family Suffering From Becker's Myotonia 114
Role of receptor protein tyrosine phosphatase α (RPTPα) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels 112
Involvement of Barttin Subunit in Pharmacological Potentiation of CLC-K Channels Expressed in Xenopus Oocytes 111
Identification of a new de novo mutation underlying regressive episodic ataxia type I 110
Therapeutic Approaches to Tuberous Sclerosis Complex: From Available Therapies to Promising Drug Targets 109
Blockers of Skeletal Muscle Nav1.4 Channels: From Therapy of Myotonic Syndrome to Molecular Determinants of Pharmacological Action and Back. 107
Clinical and Functional Study of a De Novo Variant in the PVP Motif of Kv1.1 Channel Associated with Epilepsy, Developmental Delay and Ataxia 107
Effects of Episodic Ataxia-Associated Mutations on hKv1.4 1.1/Kvbeta1 channels 107
KIDNEY CLC-K CHLORIDE CHANNELS SHOW DIFFERENTIAL PHARMACOLOGICAL PROFILES DEPENDING ON THE HETEROLOGOUS EXPRESSION SYSTEM 106
Premature stop codons in a facilitating EF-hand splice variant of CaV2.1 cause episodic ataxia type 2 106
I-J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes 104
Dapagliflozin protects the kidney in a non-diabetic model of cardiorenal syndrome 103
Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research 103
The emerging role of the inwardly rectifying K + channels in autism spectrum disorders and epilepsy 99
Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes 99
Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions 98
Natural ClC-1 mutations causing myotonia congenita reduce sensitivity to 9-AC 98
Role of inwardly-rectifying potassium channels Kir5.1 in learning and memory processes in a mouse knock-out model 97
Episodic Ataxia Type 1 Mutation F184C Alters Zn2+-Induced Modulation of the Human K+ Channel Kv1.4-Kv1.1/Kvb1.1 96
Musculoskeletal Features without Ataxia Associated with a Novel de novo Mutation in KCNA1 Impairing the Voltage Sensitivity of Kv1.1 Channel 96
Copertina della rivista Neuroscience 157 (3). A novel mutation identified in an Italian family displaying episodic ataxia, neuromyotonia and epilepsy 94
Functional Characterization of an Episodic Ataxia Type-1 Mutation Occurring in the S1 Segment of hKv1.1 Channels. 94
Trace amines depress D2-autoreceptor-mediated responses on midbrain dopaminergic cells. 93
Episodic Ataxia Type 1 Mutations Affect Fast Inactivation of K+ Channels by a Reduction in Either Subunit Surface Expression or Affinity for Inactivation Domain 92
Differential pH-sensitivity of Kir4.1 and Kir4.2 and modulation by heteropolymerisation with Kir5.1 91
Major channels involved in neuropsychiatric disorders and therapeutic perspectives 90
The Biallelic Inheritance of Two Novel SCN1A Variants Results in Developmental and Epileptic Encephalopathy Responsive to Levetiracetam 89
Mutations in MYBPC3 and MYH7 in Association with Brugada Type 1 ECG Pattern: Overlap between Brugada Syndrome and Hypertrophic Cardiomyopathy? 88
Modulation of delayed rectifier K+ channels by 5HT2c receptors 88
Coexistence of SCN4A and CLCN1 mutations in a family with atypical myotonic features: A clinical and functional study 87
Brugada Syndrome: More than a Monogenic Channelopathy 86
Sarcoplasmic Reticulum Ca2+ Buffer Proteins: A Focus on the Yet-To-Be-Explored Role of Sarcalumenin in Skeletal Muscle Health and Disease 86
The neurobiology of episodic ataxia type 1: a Shaker-like K+ channel disorder. 85
Identification and functional characterization of a novel mutation in the KCNA1 gene of a Sicilian family affected by episodic ataxia type 1 83
Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker 83
Mutations in KCNA1 gene associated with episodic ataxia type-1 sindrome impair heteromeric voltage-gated K+ channel function 82
Modification by ageing of the tetrodotoxin-sensitive sodium channels in rat skeletal muscle fibres 82
Episodic ataxia type 1 mutations cause loss-of-function impairments of heteromeric channels formed by the Kv1.4 and Kv1.1 subunits 81
Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity 81
Pleiotropic Effects of Direct Oral Anticoagulants in Chronic Heart Failure and Atrial Fibrillation: Machine Learning Analysis 81
Effects of sacubitril-valsartan on aging-related cardiac dysfunction 80
Modulation of hKv 1.1 and hKv 1.2 voltage gating and C-type inactivation by 5-HT2C receptors 80
Novel mutations of Kir2.1 underlying Andersen’s syndrome are non-functional and have a dominant negative effect on the wild –type allele 80
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvbeta1 Channel 80
Functional Properties of Voltage-Gated Potassium Channels Probed with Methanethiosulfonate Reagents 79
Late onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A. 78
Gain-of-function of the inwardly rectifying K+ channel Kir4.1 contributes to autism with seizures and intellectual disability 77
Gating properties of human heteromeric voltage-gated potassium channels and effects of episodic ataxia type-1 mutations 77
Totale 12.259
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Categoria #
all - tutte 59.017
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.017
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022674 0 0 7 45 25 52 35 41 45 64 162 198
2022/20231.187 157 123 101 106 117 160 22 125 185 25 35 31
2023/2024415 26 80 27 37 39 101 6 15 11 29 9 35
2024/20252.169 54 15 170 81 76 223 229 202 131 111 272 605
2025/20265.134 577 199 378 457 529 267 576 151 598 457 247 698
2026/2027639 224 281 134 0 0 0 0 0 0 0 0 0
Totale 14.561