IRIS
IMBRICI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 4.846
EU - Europa 1.072
AS - Asia 335
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 6.257
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Nazione #
US - Stati Uniti d'America 4.843
SE - Svezia 301
CN - Cina 271
DE - Germania 193
IT - Italia 181
UA - Ucraina 126
FI - Finlandia 83
GB - Regno Unito 76
RU - Federazione Russa 39
FR - Francia 32
VN - Vietnam 28
BE - Belgio 21
IN - India 20
IE - Irlanda 7
NL - Olanda 7
SG - Singapore 5
CA - Canada 3
TR - Turchia 3
AT - Austria 2
AU - Australia 1
BD - Bangladesh 1
CH - Svizzera 1
CL - Cile 1
CY - Cipro 1
DK - Danimarca 1
ES - Italia 1
EU - Europa 1
ID - Indonesia 1
IR - Iran 1
JP - Giappone 1
KR - Corea 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PL - Polonia 1
SA - Arabia Saudita 1
Totale 6.257
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Città #
Fairfield 737
Woodbridge 608
Houston 446
Chandler 430
Ashburn 318
Jacksonville 317
Cambridge 269
Seattle 269
Nyköping 257
Ann Arbor 208
Wilmington 206
Lawrence 102
Roxbury 99
Nanjing 86
Inglewood 81
Bari 74
Des Moines 70
New York 57
Beijing 46
San Diego 35
Boardman 32
Princeton 32
Dong Ket 28
Nanchang 27
Hebei 25
Shenyang 25
Paris 22
London 19
Pune 19
Brussels 17
Los Angeles 14
Jiaxing 12
Milan 12
Tianjin 12
Dearborn 10
Brooklyn 9
Taranto 9
Norwalk 8
Washington 8
Changsha 7
Dublin 7
Falls Church 6
Grafing 6
Montignoso 6
Auburn Hills 5
Guangzhou 5
Singapore 5
Taizhou 5
Hefei 4
Helsinki 4
Jinan 4
Mottola 4
Redwood City 4
Waanrode 4
Acton 3
Cisano Bergamasco 3
Esslingen am Neckar 3
Florence 3
Kunming 3
Perugia 3
Prescot 3
Toronto 3
Zhengzhou 3
Adelfia 2
Brescia 2
Chicago 2
Chiswick 2
Genoa 2
Hohenstein-Ernstthal 2
Magliano Alpi 2
Monmouth Junction 2
Rome 2
San Mateo 2
Settingiano 2
Vienna 2
Vinovo 2
Zogno 2
Acquaviva delle Fonti 1
Amsterdam 1
Andria 1
Apricena 1
Aradeo 1
Ardabil 1
Auckland 1
Augusta 1
Castelnuovo Rangone 1
Copenhagen 1
Corato 1
Dallas 1
Denver 1
Dhaka 1
Fasano 1
Fort Worth 1
Frankfurt am Main 1
Giresun 1
Gravina In Puglia 1
Haikou 1
Hangzhou 1
Harbin 1
Indiana 1
Totale 5.209
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Nome #
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 156
ClC-1 chloride channels: state-of-the-art research and future challenges 151
ATP Sensitive Potassium Channels in the Skeletal Muscle Function: Involvement of the KCNJ11(Kir6.2) Gene in the Determination of Mechanical Warner Bratzer Shear Force 135
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 135
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 127
Kidney CLC-K Chloride Channels Show Differential Pharmacological Profiles Depending on the Heterologous Expression System 125
Ion channels in drug discovery and safety pharmacology 119
Characterization of Student Drinking Behaviors at the Beginning of the First Academic Year at One University in Southern Italy 111
ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation 109
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 107
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 105
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 105
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 103
pH Dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia 102
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia 101
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature 98
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 93
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 91
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 90
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 89
Andersen-Tawil syndrome: New potassium channel mutations and possible phenotypic variation 88
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 83
Episodic Ataxias as Ion Channel Diseases. 82
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 82
Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene 82
The Kir5.1 Potassium Channel is an Important Determinant of Neuronal PCO2/pH Sensitivity. 80
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 80
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia—authors’ response 79
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 78
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 74
Late-onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A 74
Involvement of Barttin Subunit in Pharmacological Potentiation of CLC-K Channels Expressed in Xenopus Oocytes 72
Autism with seizure and intellectual disability: possible causative role of gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1 71
A Novel KCNA1 Mutation Identified in an Italian Family Affected by Episodic Ataxia Type 1. 70
Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research 70
Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1 69
Role of receptor protein tyrosine phosphatase α (RPTPα) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels 68
Episodic Ataxia Type 1 Mutations Affect Fast Inactivation of K+ Channels by a Reduction in Either Subunit Surface Expression or Affinity for Inactivation Domain 68
Premature stop codons in a facilitating EF-hand splice variant of CaV2.1 cause episodic ataxia type 2 65
Kidney CLC-K chloride channels inhibitors: structure-based studies and efficacy in hypertension and associated CLC-K polymorphisms. 65
KIDNEY CLC-K CHLORIDE CHANNELS SHOW DIFFERENTIAL PHARMACOLOGICAL PROFILES DEPENDING ON THE HETEROLOGOUS EXPRESSION SYSTEM 64
Ion channels gene expression analysis in myotonia congenita patients carrying ClC-1 chloride channel mutations 64
Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes 63
Effects of Episodic Ataxia-Associated Mutations on hKv1.4 1.1/Kvbeta1 channels 61
All atom molecular dynamics simulation of the K+ Channel Chimera Kv1.2/2.1 61
I-J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes 61
Identification of a new de novo mutation underlying regressive episodic ataxia type I 61
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 60
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 60
Functional Characterization of an Episodic Ataxia Type-1 Mutation Occurring in the S1 Segment of hKv1.1 Channels. 59
Role of inwardly-rectifying potassium channels Kir5.1 in learning and memory processes in a mouse knock-out model 58
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 58
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 58
Trace amines depress D2-autoreceptor-mediated responses on midbrain dopaminergic cells. 56
Skeletal muscle ClC-1 chloride channels in health and diseases 56
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvb1 Channel 55
Functional Study of Novel Bartter's Syndrome Mutations in ClC-Kb and Rescue by the Accessory Subunit Barttin Toward Personalized Medicine 55
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability 53
Episodic Ataxia Type 1 Mutation F184C Alters Zn2+-Induced Modulation of the Human K+ Channel Kv1.4-Kv1.1/Kvb1.1 52
Differential pH-sensitivity of Kir4.1 and Kir4.2 and modulation by heteropolymerisation with Kir5.1 50
Novel mutations of Kir2.1 underlying Andersen’s syndrome are non-functional and have a dominant negative effect on the wild –type allele 47
Copertina della rivista Neuroscience 157 (3). A novel mutation identified in an Italian family displaying episodic ataxia, neuromyotonia and epilepsy 47
Kv1.1 channelopathies: Pathophysiological mechanisms and therapeutic approaches 47
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvbeta1 Channel 46
The neurobiology of episodic ataxia type 1: a Shaker-like K+ channel disorder. 46
Episodic ataxia type 1 mutations cause loss-of-function impairments of heteromeric channels formed by the Kv1.4 and Kv1.1 subunits 45
Modulation of delayed rectifier K+ channels by 5HT2c receptors 45
Modulation of hKv 1.1 and hKv 1.2 voltage gating and C-type inactivation by 5-HT2C receptors 44
Modification by ageing of the tetrodotoxin-sensitive sodium channels in rat skeletal muscle fibres 44
Pathomechanisms of a CLCN1 Mutation Found in a Russian Family Suffering From Becker's Myotonia 43
The emerging role of the inwardly rectifying K + channels in autism spectrum disorders and epilepsy 42
Identification and functional characterization of a novel mutation in the KCNA1 gene of a Sicilian family affected by episodic ataxia type 1 42
Major channels involved in neuropsychiatric disorders and therapeutic perspectives 42
Gain-of-function of the inwardly rectifying K+ channel Kir4.1 contributes to autism with seizures and intellectual disability 41
Musculoskeletal Features without Ataxia Associated with a Novel de novo Mutation in KCNA1 Impairing the Voltage Sensitivity of Kv1.1 Channel 40
Role of the S1 segment in the voltage-dependent gating of Kv1.1 channels revealed by naturally occurring pathogenic mutations 37
Mutations in KCNA1 gene associated with episodic ataxia type-1 sindrome impair heteromeric voltage-gated K+ channel function 37
Modification by aging of the TTX-sensitive sodium channel in rat skeletal muscle fibres 37
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 37
Mutations in KCNA1 affect stoichiometry and fast inactivation of heteromeric K+ channels. 36
Natural ClC-1 mutations causing myotonia congenita reduce sensitivity to 9-AC 36
Human voltage-dependent potassium channel heteropolymerization results in episodic ataxia type-1 myokymia syndrome. 35
EA-1 mutations alter the fast inactivation properties of Kv1.1 channels conferred by Kv1.4 and Kvbeta1.1 subunits 35
Gating properties of human heteromeric voltage-gated potassium channels and effects of episodic ataxia type-1 mutations 35
Copertina della rivista The Journal of Physiology 35
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy 35
Episodic ataxia type-1 mutations alter the open state stability of voltage-gated K+ channels and the cell resting potential. 32
Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity 32
Functional Properties of Voltage-Gated Potassium Channels Probed with Methanethiosulfonate Reagents 31
Late onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A. 31
Episodic Ataxia Type 1 Mutations in the KCNA1 Gene Impair the Fast Inactivation Properties of the Human K+ Channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2 30
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Voltage-gated calcium channels modulate synaptic transmission at vestibular neurons 28
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders 27
Functional determinants of episodic ataxia/myokymia syndrome. 22
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Ion Channels Involvement in Neurodevelopmental Disorders 20
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Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker 19
Totale 6.334
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Categoria #
all - tutte 25.996
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.996
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019431 0 0 0 0 0 0 0 0 0 0 216 215
2019/20201.510 271 88 76 149 146 93 151 115 175 80 125 41
2020/20211.145 125 64 95 118 91 55 111 59 102 170 63 92
2021/2022818 34 110 7 45 25 52 35 41 45 64 162 198
2022/20231.187 157 123 101 106 117 160 22 125 185 25 35 31
2023/2024371 26 80 27 37 39 101 6 15 11 29 0 0
Totale 6.575