IRIS
IMBRICI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 6.619
AS - Asia 2.936
EU - Europa 1.998
SA - Sud America 820
AF - Africa 103
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 12.484
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Nazione #
US - Stati Uniti d'America 6.513
SG - Singapore 1.228
BR - Brasile 671
CN - Cina 606
HK - Hong Kong 372
IT - Italia 361
SE - Svezia 310
DE - Germania 293
RU - Federazione Russa 264
VN - Vietnam 230
FR - Francia 189
FI - Finlandia 148
GB - Regno Unito 140
UA - Ucraina 135
IN - India 109
ID - Indonesia 70
AR - Argentina 56
BD - Bangladesh 54
CA - Canada 41
MX - Messico 41
TR - Turchia 38
IQ - Iraq 32
NL - Olanda 32
BE - Belgio 29
PK - Pakistan 27
ZA - Sudafrica 26
SA - Arabia Saudita 25
EC - Ecuador 23
JP - Giappone 21
PL - Polonia 21
MA - Marocco 17
TN - Tunisia 17
AT - Austria 15
VE - Venezuela 15
CO - Colombia 14
ES - Italia 14
UZ - Uzbekistan 14
CL - Cile 13
PH - Filippine 13
PY - Paraguay 12
AE - Emirati Arabi Uniti 11
MY - Malesia 10
NP - Nepal 10
EG - Egitto 9
CI - Costa d'Avorio 8
IE - Irlanda 8
KZ - Kazakistan 8
CR - Costa Rica 7
KE - Kenya 7
BO - Bolivia 6
CZ - Repubblica Ceca 6
DZ - Algeria 6
JO - Giordania 6
OM - Oman 6
LB - Libano 5
PE - Perù 5
PS - Palestinian Territory 5
PT - Portogallo 5
TH - Thailandia 5
TW - Taiwan 5
AL - Albania 4
AU - Australia 4
CH - Svizzera 4
ET - Etiopia 4
IL - Israele 4
RS - Serbia 4
GE - Georgia 3
HN - Honduras 3
KG - Kirghizistan 3
KR - Corea 3
LV - Lettonia 3
UY - Uruguay 3
AZ - Azerbaigian 2
BH - Bahrain 2
DK - Danimarca 2
DM - Dominica 2
DO - Repubblica Dominicana 2
IR - Iran 2
LT - Lituania 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BT - Bhutan 1
BY - Bielorussia 1
CV - Capo Verde 1
CY - Cipro 1
EU - Europa 1
GN - Guinea 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
HU - Ungheria 1
Totale 12.468
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Città #
Fairfield 738
Ashburn 615
Woodbridge 608
Singapore 603
Houston 452
Chandler 431
San Jose 407
Hong Kong 367
Jacksonville 319
Seattle 277
Cambridge 269
Nyköping 257
Ann Arbor 208
Wilmington 207
Beijing 179
Lauterbourg 127
Dallas 109
Lawrence 102
Roxbury 99
Bari 91
Nanjing 89
Inglewood 81
Los Angeles 81
New York 79
Council Bluffs 77
Des Moines 70
Ho Chi Minh City 63
Jakarta 53
Helsinki 52
Hanoi 43
Boardman 42
Santa Clara 42
São Paulo 42
Buffalo 37
San Diego 35
London 33
Princeton 32
Falkenstein 31
Moscow 29
Dong Ket 28
Nanchang 27
Brooklyn 26
Brussels 25
Hebei 25
Munich 25
Shenyang 25
Chicago 24
Milan 24
Paris 23
Pune 21
Chennai 20
Rio de Janeiro 20
Tokyo 20
Warsaw 17
Brasília 16
Frankfurt am Main 16
Jiaxing 16
Johannesburg 16
Mexico City 16
Nuremberg 16
Turku 16
Baghdad 14
Denver 14
Jeddah 14
Dhaka 13
Montreal 13
The Dalles 13
Ankara 12
Atlanta 12
Columbus 12
Guangzhou 12
Tashkent 12
Tianjin 12
Toronto 12
Washington 12
Haiphong 11
Rome 11
Belo Horizonte 10
Curitiba 10
Dearborn 10
Orem 10
Salvador 10
Taranto 10
Vienna 10
Boston 9
Changsha 9
Guayaquil 9
Norwalk 9
Poplar 9
Shanghai 9
Stockholm 9
Tunis 9
Abidjan 8
Biên Hòa 8
Casablanca 8
Dublin 8
Düsseldorf 8
Lahore 8
Naples 8
Porto Alegre 8
Totale 8.343
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Nome #
ATP Sensitive Potassium Channels in the Skeletal Muscle Function: Involvement of the KCNJ11(Kir6.2) Gene in the Determination of Mechanical Warner Bratzer Shear Force 225
ClC-1 chloride channels: state-of-the-art research and future challenges 216
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 209
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 203
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 197
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 189
ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation 186
Characterization of Student Drinking Behaviors at the Beginning of the First Academic Year at One University in Southern Italy 180
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 173
Ion channels in drug discovery and safety pharmacology 173
Kidney CLC-K Chloride Channels Show Differential Pharmacological Profiles Depending on the Heterologous Expression System 167
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 164
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 163
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 159
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 152
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 143
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 142
Andersen-Tawil syndrome: New potassium channel mutations and possible phenotypic variation 141
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature 139
pH Dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia 138
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia 132
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 132
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 131
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 126
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 126
A Novel KCNA1 Mutation Identified in an Italian Family Affected by Episodic Ataxia Type 1. 124
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 121
Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene 121
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 120
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders 119
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 116
Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita 115
Autism with seizure and intellectual disability: possible causative role of gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1 115
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia—authors’ response 114
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 113
Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1 113
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability 113
A novel kcna2 variant in a patient with non-progressive congenital ataxia and epilepsy: Functional characterization and sensitivity to 4-aminopyridine 113
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 112
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 109
The Kir5.1 Potassium Channel is an Important Determinant of Neuronal PCO2/pH Sensitivity. 108
Kv1.1 channelopathies: Pathophysiological mechanisms and therapeutic approaches 108
Skeletal muscle ClC-1 chloride channels in health and diseases 108
Episodic Ataxias as Ion Channel Diseases. 107
All atom molecular dynamics simulation of the K+ Channel Chimera Kv1.2/2.1 106
Kidney CLC-K chloride channels inhibitors: structure-based studies and efficacy in hypertension and associated CLC-K polymorphisms. 106
Functional Study of Novel Bartter's Syndrome Mutations in ClC-Kb and Rescue by the Accessory Subunit Barttin Toward Personalized Medicine 106
Involvement of Barttin Subunit in Pharmacological Potentiation of CLC-K Channels Expressed in Xenopus Oocytes 105
Ion channels gene expression analysis in myotonia congenita patients carrying ClC-1 chloride channel mutations 105
Late-onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A 102
KIDNEY CLC-K CHLORIDE CHANNELS SHOW DIFFERENTIAL PHARMACOLOGICAL PROFILES DEPENDING ON THE HETEROLOGOUS EXPRESSION SYSTEM 101
Role of receptor protein tyrosine phosphatase α (RPTPα) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels 101
I-J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes 100
Pathomechanisms of a CLCN1 Mutation Found in a Russian Family Suffering From Becker's Myotonia 100
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvb1 Channel 99
Identification of a new de novo mutation underlying regressive episodic ataxia type I 99
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy 99
Premature stop codons in a facilitating EF-hand splice variant of CaV2.1 cause episodic ataxia type 2 98
Blockers of Skeletal Muscle Nav1.4 Channels: From Therapy of Myotonic Syndrome to Molecular Determinants of Pharmacological Action and Back. 97
Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy 97
Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research 97
Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes 96
Dapagliflozin protects the kidney in a non-diabetic model of cardiorenal syndrome 95
Effects of Episodic Ataxia-Associated Mutations on hKv1.4 1.1/Kvbeta1 channels 95
Musculoskeletal Features without Ataxia Associated with a Novel de novo Mutation in KCNA1 Impairing the Voltage Sensitivity of Kv1.1 Channel 93
Functional Characterization of an Episodic Ataxia Type-1 Mutation Occurring in the S1 Segment of hKv1.1 Channels. 92
Trace amines depress D2-autoreceptor-mediated responses on midbrain dopaminergic cells. 90
Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions 89
Role of inwardly-rectifying potassium channels Kir5.1 in learning and memory processes in a mouse knock-out model 89
Episodic Ataxia Type 1 Mutations Affect Fast Inactivation of K+ Channels by a Reduction in Either Subunit Surface Expression or Affinity for Inactivation Domain 89
Clinical and Functional Study of a De Novo Variant in the PVP Motif of Kv1.1 Channel Associated with Epilepsy, Developmental Delay and Ataxia 87
The emerging role of the inwardly rectifying K + channels in autism spectrum disorders and epilepsy 85
Episodic Ataxia Type 1 Mutation F184C Alters Zn2+-Induced Modulation of the Human K+ Channel Kv1.4-Kv1.1/Kvb1.1 82
Therapeutic Approaches to Tuberous Sclerosis Complex: From Available Therapies to Promising Drug Targets 80
Differential pH-sensitivity of Kir4.1 and Kir4.2 and modulation by heteropolymerisation with Kir5.1 79
Natural ClC-1 mutations causing myotonia congenita reduce sensitivity to 9-AC 79
Modification by ageing of the tetrodotoxin-sensitive sodium channels in rat skeletal muscle fibres 79
The Biallelic Inheritance of Two Novel SCN1A Variants Results in Developmental and Epileptic Encephalopathy Responsive to Levetiracetam 78
Major channels involved in neuropsychiatric disorders and therapeutic perspectives 78
The neurobiology of episodic ataxia type 1: a Shaker-like K+ channel disorder. 78
Copertina della rivista Neuroscience 157 (3). A novel mutation identified in an Italian family displaying episodic ataxia, neuromyotonia and epilepsy 77
Sarcoplasmic Reticulum Ca2+ Buffer Proteins: A Focus on the Yet-To-Be-Explored Role of Sarcalumenin in Skeletal Muscle Health and Disease 77
Coexistence of SCN4A and CLCN1 mutations in a family with atypical myotonic features: A clinical and functional study 76
Brugada Syndrome: More than a Monogenic Channelopathy 76
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvbeta1 Channel 76
Episodic ataxia type 1 mutations cause loss-of-function impairments of heteromeric channels formed by the Kv1.4 and Kv1.1 subunits 75
Functional Properties of Voltage-Gated Potassium Channels Probed with Methanethiosulfonate Reagents 75
Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker 75
Novel mutations of Kir2.1 underlying Andersen’s syndrome are non-functional and have a dominant negative effect on the wild –type allele 74
Modulation of delayed rectifier K+ channels by 5HT2c receptors 73
Modulation of hKv 1.1 and hKv 1.2 voltage gating and C-type inactivation by 5-HT2C receptors 72
Identification and functional characterization of a novel mutation in the KCNA1 gene of a Sicilian family affected by episodic ataxia type 1 72
Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity 72
Pleiotropic Effects of Direct Oral Anticoagulants in Chronic Heart Failure and Atrial Fibrillation: Machine Learning Analysis 72
Biophysical Aspects of Neurodegenerative and Neurodevelopmental Disorders Involving Endo-/Lysosomal CLC Cl-/H+ Antiporters 68
Gain-of-function of the inwardly rectifying K+ channel Kir4.1 contributes to autism with seizures and intellectual disability 67
Gating properties of human heteromeric voltage-gated potassium channels and effects of episodic ataxia type-1 mutations 66
Late onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A. 66
Modification by aging of the TTX-sensitive sodium channel in rat skeletal muscle fibres 66
Functional characterization of two novel mutations in scn5a associated with brugada syndrome identified in Italian patients 66
Totale 11.067
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Categoria #
all - tutte 52.432
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.432
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021325 0 0 0 0 0 0 0 0 0 170 63 92
2021/2022818 34 110 7 45 25 52 35 41 45 64 162 198
2022/20231.187 157 123 101 106 117 160 22 125 185 25 35 31
2023/2024415 26 80 27 37 39 101 6 15 11 29 9 35
2024/20252.169 54 15 170 81 76 223 229 202 131 111 272 605
2025/20264.154 577 199 378 457 529 267 576 151 598 422 0 0
Totale 12.942