IRIS
IMBRICI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 5.877
AS - Asia 2.408
EU - Europa 1.657
SA - Sud America 660
AF - Africa 53
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 10.662
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Nazione #
US - Stati Uniti d'America 5.790
SG - Singapore 1.063
BR - Brasile 587
CN - Cina 542
HK - Hong Kong 358
SE - Svezia 310
DE - Germania 264
IT - Italia 260
RU - Federazione Russa 256
VN - Vietnam 191
UA - Ucraina 131
GB - Regno Unito 130
FI - Finlandia 109
FR - Francia 64
IN - India 62
ID - Indonesia 60
CA - Canada 37
MX - Messico 35
AR - Argentina 33
BE - Belgio 29
NL - Olanda 27
BD - Bangladesh 22
TR - Turchia 22
PL - Polonia 20
ZA - Sudafrica 17
EC - Ecuador 15
IQ - Iraq 15
AT - Austria 14
JP - Giappone 13
ES - Italia 12
AE - Emirati Arabi Uniti 8
CI - Costa d'Avorio 8
IE - Irlanda 8
TN - Tunisia 8
CL - Cile 7
CO - Colombia 7
SA - Arabia Saudita 7
MA - Marocco 6
PK - Pakistan 6
CZ - Repubblica Ceca 5
KE - Kenya 5
UZ - Uzbekistan 5
CR - Costa Rica 4
TW - Taiwan 4
AL - Albania 3
AU - Australia 3
CH - Svizzera 3
EG - Egitto 3
IL - Israele 3
KR - Corea 3
LB - Libano 3
PY - Paraguay 3
VE - Venezuela 3
BH - Bahrain 2
DM - Dominica 2
DZ - Algeria 2
IR - Iran 2
KZ - Kazakistan 2
LT - Lituania 2
LV - Lettonia 2
NP - Nepal 2
PE - Perù 2
PT - Portogallo 2
SN - Senegal 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BO - Bolivia 1
BY - Bielorussia 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
EU - Europa 1
GE - Georgia 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
JM - Giamaica 1
JO - Giordania 1
KG - Kirghizistan 1
ML - Mali 1
MY - Malesia 1
NI - Nicaragua 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PH - Filippine 1
PR - Porto Rico 1
QA - Qatar 1
SY - Repubblica araba siriana 1
Totale 10.662
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Città #
Fairfield 738
Woodbridge 608
Ashburn 543
Singapore 511
Houston 452
Chandler 431
Hong Kong 354
Jacksonville 319
Seattle 276
Cambridge 269
Nyköping 257
Ann Arbor 208
Wilmington 207
Beijing 174
Dallas 105
Lawrence 102
Roxbury 99
Nanjing 88
Bari 84
Inglewood 81
Los Angeles 78
New York 78
Des Moines 70
Ho Chi Minh City 55
Jakarta 51
Boardman 42
Santa Clara 38
São Paulo 38
Buffalo 35
San Diego 35
Hanoi 34
London 33
Princeton 32
Dong Ket 28
Moscow 28
Nanchang 27
Brooklyn 26
Brussels 25
Hebei 25
Munich 25
Shenyang 25
Chicago 22
Paris 22
Milan 21
Pune 20
Chennai 18
Council Bluffs 17
Rio de Janeiro 17
Warsaw 17
Jiaxing 16
Nuremberg 16
Turku 16
Brasília 13
Helsinki 13
Johannesburg 13
Mexico City 13
The Dalles 13
Tokyo 13
Columbus 12
Frankfurt am Main 12
Tianjin 12
Toronto 12
Denver 11
Guangzhou 11
Montreal 11
Washington 11
Dearborn 10
Haiphong 10
Vienna 10
Belo Horizonte 9
Boston 9
Changsha 9
Curitiba 9
Guayaquil 9
Norwalk 9
Poplar 9
Stockholm 9
Taranto 9
Abidjan 8
Dublin 8
Düsseldorf 8
Falkenstein 8
Lauterbourg 8
Naples 8
Porto Alegre 8
Salvador 8
Shanghai 8
Ankara 7
Orem 7
Phoenix 7
Dhaka 6
Falls Church 6
Goiânia 6
Grafing 6
Hải Dương 6
Montignoso 6
Santo André 6
Veracruz 6
Atlanta 5
Auburn Hills 5
Totale 7.368
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Nome #
ATP Sensitive Potassium Channels in the Skeletal Muscle Function: Involvement of the KCNJ11(Kir6.2) Gene in the Determination of Mechanical Warner Bratzer Shear Force 204
ClC-1 chloride channels: state-of-the-art research and future challenges 199
Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies 192
Mapping ligand binding pockets in ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid 186
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate 177
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita 176
ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation 166
Ion channels in drug discovery and safety pharmacology 165
Characterization of Student Drinking Behaviors at the Beginning of the First Academic Year at One University in Southern Italy 162
A large cohort of myotonia congenita probands: novel mutations and a high-frequency mutation region in exons 4 and 5 of the CLCN1 gene. 159
Kidney CLC-K Chloride Channels Show Differential Pharmacological Profiles Depending on the Heterologous Expression System 157
Coexistence of CLCN1 and SCN4A mutations in one family suffering from myotonia 155
A novel KCNA1 mutation in a patient with paroxysmal ataxia, myokymia, painful contractures and metabolic dysfunctions 148
The analysis of myotonia congenita mutations discloses functional clusters of amino acids within CBS2 domain and C-terminal peptide of ClC-1 channel 137
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 137
Andersen-Tawil syndrome: New potassium channel mutations and possible phenotypic variation 133
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation 131
pH Dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia 130
Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature 127
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia 123
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 120
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 115
A Novel KCNA1 Mutation Identified in an Italian Family Affected by Episodic Ataxia Type 1. 113
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 112
Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene 112
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 111
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 receptor blockers valsartan and olmesartan 111
Functional characterization of a C-terminal Nav1.4 mutation found in a patient presenting with myotonia and congenital myasthenia syndrome 109
Functional characterization of ClC-1 mutations from patients affected by recessive myotonia congenita presenting with different clinical phenotypes. 107
Dysfunction of the brain calcium channel CaV2.1 in absence epilepsy and episodic ataxia—authors’ response 106
Contributions of the central hydrophobic residue in the PXP motif of Voltage-Dependent K+ Channels to S6 flexibility and Gating Properties 105
Autism with seizure and intellectual disability: possible causative role of gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1 104
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 104
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 103
Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K+ channel function 103
The Kir5.1 Potassium Channel is an Important Determinant of Neuronal PCO2/pH Sensitivity. 101
Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1 99
Episodic Ataxias as Ion Channel Diseases. 98
Chaperone activity of niflumic acid on ClC-1 chloride channel mutants causing myotonia congenita 96
Involvement of Barttin Subunit in Pharmacological Potentiation of CLC-K Channels Expressed in Xenopus Oocytes 96
Kidney CLC-K chloride channels inhibitors: structure-based studies and efficacy in hypertension and associated CLC-K polymorphisms. 96
Role of receptor protein tyrosine phosphatase α (RPTPα) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels 95
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders 95
All atom molecular dynamics simulation of the K+ Channel Chimera Kv1.2/2.1 94
Late-onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A 94
Functional Study of Novel Bartter's Syndrome Mutations in ClC-Kb and Rescue by the Accessory Subunit Barttin Toward Personalized Medicine 94
I-J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes 92
KIDNEY CLC-K CHLORIDE CHANNELS SHOW DIFFERENTIAL PHARMACOLOGICAL PROFILES DEPENDING ON THE HETEROLOGOUS EXPRESSION SYSTEM 91
Skeletal muscle ClC-1 chloride channels in health and diseases 91
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability 91
Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes 90
Premature stop codons in a facilitating EF-hand splice variant of CaV2.1 cause episodic ataxia type 2 90
Paving the way for Bartter syndrome type 3 drug discovery: a hope from basic research 90
Ion channels gene expression analysis in myotonia congenita patients carrying ClC-1 chloride channel mutations 90
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvb1 Channel 88
Functional Characterization of an Episodic Ataxia Type-1 Mutation Occurring in the S1 Segment of hKv1.1 Channels. 87
Effects of Episodic Ataxia-Associated Mutations on hKv1.4 1.1/Kvbeta1 channels 86
Episodic Ataxia Type 1 Mutations Affect Fast Inactivation of K+ Channels by a Reduction in Either Subunit Surface Expression or Affinity for Inactivation Domain 85
Identification of a new de novo mutation underlying regressive episodic ataxia type I 85
Kv1.1 channelopathies: Pathophysiological mechanisms and therapeutic approaches 84
Pathomechanisms of a CLCN1 Mutation Found in a Russian Family Suffering From Becker's Myotonia 84
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy 84
Trace amines depress D2-autoreceptor-mediated responses on midbrain dopaminergic cells. 81
A novel kcna2 variant in a patient with non-progressive congenital ataxia and epilepsy: Functional characterization and sensitivity to 4-aminopyridine 79
Role of inwardly-rectifying potassium channels Kir5.1 in learning and memory processes in a mouse knock-out model 78
Musculoskeletal Features without Ataxia Associated with a Novel de novo Mutation in KCNA1 Impairing the Voltage Sensitivity of Kv1.1 Channel 78
Dapagliflozin protects the kidney in a non-diabetic model of cardiorenal syndrome 74
Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy 74
Episodic Ataxia Type 1 Mutation F184C Alters Zn2+-Induced Modulation of the Human K+ Channel Kv1.4-Kv1.1/Kvb1.1 74
Modification by ageing of the tetrodotoxin-sensitive sodium channels in rat skeletal muscle fibres 72
Blockers of Skeletal Muscle Nav1.4 Channels: From Therapy of Myotonic Syndrome to Molecular Determinants of Pharmacological Action and Back. 71
Differential pH-sensitivity of Kir4.1 and Kir4.2 and modulation by heteropolymerisation with Kir5.1 70
The emerging role of the inwardly rectifying K + channels in autism spectrum disorders and epilepsy 70
Major channels involved in neuropsychiatric disorders and therapeutic perspectives 68
The neurobiology of episodic ataxia type 1: a Shaker-like K+ channel disorder. 68
Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity 67
Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions 66
Novel mutations of Kir2.1 underlying Andersen’s syndrome are non-functional and have a dominant negative effect on the wild –type allele 66
Copertina della rivista Neuroscience 157 (3). A novel mutation identified in an Italian family displaying episodic ataxia, neuromyotonia and epilepsy 66
The Episodic Ataxia Type 1 Mutation F184C Alters the Zn2+ Modulation of the Human Kv1.4-Kv1.1/Kvbeta1 Channel 66
Natural ClC-1 mutations causing myotonia congenita reduce sensitivity to 9-AC 66
Episodic ataxia type 1 mutations cause loss-of-function impairments of heteromeric channels formed by the Kv1.4 and Kv1.1 subunits 64
Modulation of hKv 1.1 and hKv 1.2 voltage gating and C-type inactivation by 5-HT2C receptors 63
Identification and functional characterization of a novel mutation in the KCNA1 gene of a Sicilian family affected by episodic ataxia type 1 63
Clinical and Functional Study of a De Novo Variant in the PVP Motif of Kv1.1 Channel Associated with Epilepsy, Developmental Delay and Ataxia 62
Brugada Syndrome: More than a Monogenic Channelopathy 60
Gain-of-function of the inwardly rectifying K+ channel Kir4.1 contributes to autism with seizures and intellectual disability 59
Modulation of delayed rectifier K+ channels by 5HT2c receptors 59
Modification by aging of the TTX-sensitive sodium channel in rat skeletal muscle fibres 59
Sarcoplasmic Reticulum Ca2+ Buffer Proteins: A Focus on the Yet-To-Be-Explored Role of Sarcalumenin in Skeletal Muscle Health and Disease 58
Mutations in KCNA1 affect stoichiometry and fast inactivation of heteromeric K+ channels. 56
Functional Properties of Voltage-Gated Potassium Channels Probed with Methanethiosulfonate Reagents 56
Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker 56
The Biallelic Inheritance of Two Novel SCN1A Variants Results in Developmental and Epileptic Encephalopathy Responsive to Levetiracetam 55
Role of the S1 segment in the voltage-dependent gating of Kv1.1 channels revealed by naturally occurring pathogenic mutations 55
Gating properties of human heteromeric voltage-gated potassium channels and effects of episodic ataxia type-1 mutations 55
Late onset episodic ataxia type 2 due to an in-frame insertion in CACNA1A. 55
Partial recovery of skeletal muscle sodium channel properties in aged rats chronically treated with growth hormone or the GH-secretagogue hexarelin 55
Therapeutic Approaches to Tuberous Sclerosis Complex: From Available Therapies to Promising Drug Targets 54
Mutations in KCNA1 gene associated with episodic ataxia type-1 sindrome impair heteromeric voltage-gated K+ channel function 54
Totale 9.717
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Categoria #
all - tutte 49.070
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.070
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021652 0 0 0 0 0 55 111 59 102 170 63 92
2021/2022818 34 110 7 45 25 52 35 41 45 64 162 198
2022/20231.187 157 123 101 106 117 160 22 125 185 25 35 31
2023/2024415 26 80 27 37 39 101 6 15 11 29 9 35
2024/20252.169 54 15 170 81 76 223 229 202 131 111 272 605
2025/20262.330 577 199 378 457 529 190 0 0 0 0 0 0
Totale 11.118