IRIS
CAVALLUZZI, MARIA MADDALENA
 Distribuzione geografica
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Continente #
NA - Nord America 4.056
EU - Europa 1.088
AS - Asia 626
SA - Sud America 12
OC - Oceania 6
AF - Africa 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.793
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Nazione #
US - Stati Uniti d'America 4.037
CN - Cina 376
IT - Italia 298
SE - Svezia 291
SG - Singapore 182
UA - Ucraina 111
DE - Germania 88
FI - Finlandia 83
GB - Regno Unito 64
RU - Federazione Russa 47
FR - Francia 36
BE - Belgio 23
IN - India 22
CA - Canada 18
VN - Vietnam 13
IE - Irlanda 11
JP - Giappone 9
NL - Olanda 8
BR - Brasile 6
LT - Lituania 6
AU - Australia 5
TR - Turchia 5
KR - Corea 4
CZ - Repubblica Ceca 3
EG - Egitto 3
HK - Hong Kong 3
IR - Iran 3
PL - Polonia 3
PT - Portogallo 3
RO - Romania 3
AT - Austria 2
BO - Bolivia 2
CO - Colombia 2
ES - Italia 2
RS - Serbia 2
SA - Arabia Saudita 2
TH - Thailandia 2
BD - Bangladesh 1
CH - Svizzera 1
EC - Ecuador 1
EE - Estonia 1
EU - Europa 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
MX - Messico 1
NZ - Nuova Zelanda 1
PH - Filippine 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 5.793
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Città #
Fairfield 535
Chandler 400
Woodbridge 321
Ashburn 286
Houston 268
Jacksonville 262
Nyköping 240
Seattle 232
Cambridge 198
Ann Arbor 178
Wilmington 178
Singapore 136
Bari 96
Lawrence 90
Roxbury 89
New York 83
Nanjing 72
Beijing 59
Des Moines 56
Princeton 56
Boardman 46
Inglewood 30
Los Angeles 29
San Diego 29
Brooklyn 26
Brussels 22
Jiaxing 22
London 22
Guangzhou 19
Santa Clara 19
Shenyang 17
Rome 16
Hebei 15
Helsinki 15
Munich 15
Paris 15
Toronto 15
Dearborn 13
Dong Ket 13
Nanchang 13
Pune 12
Tianjin 12
Changsha 11
Dublin 11
Marseille 10
Milan 10
San Francisco 10
Wuhan 10
Leawood 8
Redwood City 8
Shanghai 8
Brescia 6
Jinan 6
Norwalk 6
San Mateo 6
Triggiano 6
Washington 6
Hefei 5
Kilburn 5
Tokyo 5
Zhengzhou 5
Bitonto 4
Bologna 4
Chicago 4
Melbourne 4
Mumbai 4
Naples 4
Wuxi 4
Ardabil 3
Belém 3
Council Bluffs 3
Florence 3
Frankfurt am Main 3
Fuzhou 3
Grottaglie 3
Kunming 3
Lentini 3
Palermo 3
Adelfia 2
Arnesano 2
Auburn Hills 2
Augusta 2
Bogotá 2
Bragança 2
Bristol 2
Cairo 2
Chengdu 2
Chieti 2
Chongqing 2
Dongguan 2
Ferrara 2
Gdansk 2
Genoa 2
Ghaziabad 2
Haikou 2
Hanover 2
Hartford 2
Indiana 2
Islington 2
Istanbul 2
Totale 4.514
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Nome #
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 120
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 119
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 115
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 113
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 111
The chemistry and pharmacology of citrus limonoids 111
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 111
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 109
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 108
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 106
Recent trends in the discovery of small molecule blockers of sodium channels 106
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 104
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 102
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 98
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 95
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 94
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 93
null 91
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 91
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 90
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 88
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 86
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 84
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 82
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 81
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 81
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 79
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 78
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 77
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 75
Discovery of a new mexiletine-derived agonist of the hERG K+channel 75
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 73
Lubeluzole: from anti-ischemic to chemosensitizing agent 73
2-(9-Antryl)alcanoic acids as chloride channel modulators 71
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 70
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 66
Synthesis of (R)-, (S)-, and (RS)-hydroxymethylmexiletine one of the major metabolites of mexiletine 64
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole 64
null 64
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 62
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 61
Preclinical in vitro and in vivo evaluation of sodium channel blockers as possible alternative to mexiletine in the treatment of myotonia 61
Derivati idrossilati della mexiletina come tools farmacologici nello studio dell'attività di blocco dei canali sodici 60
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 60
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 59
Covid-19, chloroquine repurposing, and cardiac safety concern: Chirality might help 59
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 57
Molecular determinants of human voltage-gated sodium channel blockade by lubeluzole 57
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 56
null 56
Novel lysophosphatidic acid receptor 6 antagonists inhibit hepatocellular carcinoma growth through affecting mitochondrial function 56
null 56
Pilsicainide and its oxymethylene analog: Facile alternative synthesis and in vitro testing on human skeletal muscle sodium channels 54
Targeting the pregnane X receptor using microbial metabolite mimicry 52
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 52
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 51
Sintesi enantiospecifica one-step di acidi O-aril ed O-eteroaril mandelici, utilizzabili come agenti di solvatazione chirale 50
Separation and quantitative determination of mexiletine and its metabolites by capillary zone electrophoresis 49
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 49
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 48
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 48
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 45
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 45
Sintesi alternativa del lubeluzolo e del suo enantiomero e valutazione come agenti in grado di potenziare l'effetto di farmaci antitumorali. 45
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 44
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 43
Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials 41
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 40
Design of a pharmacological rat model of myotonia congenita for antimyotonic drug screening 40
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 40
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 39
Erratum: Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+ Channels 39
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interaction at the main binding sites 38
Voltage-gated sodium channel blocking agents coupled to a ros scavenging pyrroline moiety as dual-acting twin drugs 36
Efficient Routes to Lubeluzole, Its Enantiomer, and Racemate 36
Dual-Acting Drugs: Antioxidant Activity of Voltage-Gated Sodium Channel Blocking Agents Coupled to a Pyrroline Moiety 35
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 33
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela ottimale 32
Label-free, reagentless, straightforward capillary electrophoretic method to individuate potent calmodulin ligands. 32
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies 32
Sintesi della pilsicainide e valutazione della sua attività di blocco sui canali sodici di muscolo scheletrico umano 30
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 30
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth 30
Small Molecules as MT1 And MT2 Ligands: Antioxidant Properties and in vitro Inhibition of Ca2+/CAM-Dependent Kinase II. 29
The Crystal Structure of N-[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl]-4-methoxy-N-methylbenzenesulfonamide 29
Phyllostachys Pubescens: From Traditional to Functional Food: Phyllostachys pubescens as functional food 29
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 28
Dual-acting drugs: antioxidant activity of voltage-gated sodium channel blocking agents coupled to a pyrroline moiety. 28
First synthesis and full characterization of mexiletine N-carbonyloxy beta-D-glucuronide 28
Small molecules as MT1 and MT2 ligands: antioxidant properties and in vitro inhibition of Ca2+/CaM-dependent kinase II. 26
Preparation of Chiral 2-(9-Anthryl)Alcanoic Acids, 9-Xanthenyl Isosteres, and Derivatives 26
Targeting Penicillium expansum GMC oxidoreductase with high affinity small molecules for reducing patulin production 26
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 25
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela di eluizione ottimale 24
Label-free, Reagentless, Straightforward Capillary Electrophoretic Method to Individuate Potent Calmodulin Ligands 24
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 22
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela di eluizione ottimale 22
Separation and quantitative determination of mexiletine by capillary zone electrophoresis 22
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 20
Lubeluzole Repositioning as Chemosensitizing Agent on Multidrug-Resistant Human Ovarian A2780/DX3 Cancer Cells 18
Totale 5.982
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Categoria #
all - tutte 29.474
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.474
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020712 0 0 0 0 0 64 114 90 173 76 160 35
2020/2021990 198 49 72 65 76 39 77 64 84 125 84 57
2021/2022727 41 113 29 27 5 48 29 29 51 43 112 200
2022/20231.189 170 131 66 96 122 157 17 159 182 17 47 25
2023/2024558 31 78 27 59 32 125 9 31 19 30 50 67
2024/2025555 93 40 165 65 60 132 0 0 0 0 0 0
Totale 6.147