IRIS
CAVALLUZZI, MARIA MADDALENA
 Distribuzione geografica
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Continente #
NA - Nord America 3.901
EU - Europa 943
AS - Asia 312
SA - Sud America 9
OC - Oceania 6
AF - Africa 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.175
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Nazione #
US - Stati Uniti d'America 3.890
SE - Svezia 289
IT - Italia 255
CN - Cina 247
UA - Ucraina 111
DE - Germania 71
FI - Finlandia 71
GB - Regno Unito 57
FR - Francia 36
BE - Belgio 22
IN - India 20
VN - Vietnam 13
SG - Singapore 12
IE - Irlanda 11
CA - Canada 10
NL - Olanda 6
AU - Australia 5
BR - Brasile 5
RU - Federazione Russa 4
IR - Iran 3
JP - Giappone 3
KR - Corea 3
RO - Romania 3
BO - Bolivia 2
EG - Egitto 2
HK - Hong Kong 2
SA - Arabia Saudita 2
TH - Thailandia 2
TR - Turchia 2
BD - Bangladesh 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
EE - Estonia 1
ES - Italia 1
EU - Europa 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
MX - Messico 1
NZ - Nuova Zelanda 1
PL - Polonia 1
ZA - Sudafrica 1
Totale 5.175
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Città #
Fairfield 535
Chandler 400
Woodbridge 321
Houston 266
Ashburn 263
Jacksonville 262
Nyköping 240
Seattle 228
Cambridge 198
Ann Arbor 178
Wilmington 178
Lawrence 90
Roxbury 89
Bari 88
New York 83
Nanjing 72
Des Moines 56
Princeton 56
Beijing 50
Boardman 36
Inglewood 30
San Diego 29
Brooklyn 26
Brussels 21
Jiaxing 18
London 18
Los Angeles 17
Shenyang 16
Hebei 15
Paris 15
Rome 15
Dearborn 13
Dong Ket 13
Nanchang 13
Pune 12
Tianjin 12
Dublin 11
Changsha 10
Marseille 10
San Francisco 10
Toronto 9
Leawood 8
Redwood City 8
Jinan 6
Norwalk 6
San Mateo 6
Washington 6
Hefei 5
Kilburn 5
Milan 5
Zhengzhou 5
Bologna 4
Melbourne 4
Mumbai 4
Ardabil 3
Belém 3
Bitonto 3
Florence 3
Guangzhou 3
Helsinki 3
Kunming 3
Lentini 3
Palermo 3
Triggiano 3
Adelfia 2
Arnesano 2
Auburn Hills 2
Augusta 2
Brescia 2
Cairo 2
Chengdu 2
Chicago 2
Council Bluffs 2
Ferrara 2
Fuzhou 2
Genoa 2
Haikou 2
Hanover 2
Hartford 2
Indiana 2
Islington 2
Kiev 2
Kowloon 2
Lucera 2
Monmouth Junction 2
Phoenix 2
Pontassieve 2
Riyadh 2
San Giovanni Rotondo 2
Sersale 2
Somma Vesuviana 2
Turi 2
Viareggio 2
Wuhan 2
Almere Stad 1
Altamura 1
Arezzo 1
Arzano 1
Auckland 1
Bergamo 1
Totale 4.190
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Nome #
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 114
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 113
The chemistry and pharmacology of citrus limonoids 108
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 106
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 105
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 104
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 103
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 102
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 102
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 101
Recent trends in the discovery of small molecule blockers of sodium channels 100
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 97
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 92
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 91
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Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 89
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 86
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 83
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 83
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 82
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 81
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 80
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 79
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 79
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 77
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 76
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 76
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 74
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 73
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 71
Lubeluzole: from anti-ischemic to chemosensitizing agent 71
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 70
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 65
null 64
Discovery of a new mexiletine-derived agonist of the hERG K+channel 62
Synthesis of (R)-, (S)-, and (RS)-hydroxymethylmexiletine one of the major metabolites of mexiletine 61
2-(9-Antryl)alcanoic acids as chloride channel modulators 60
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole 60
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 60
Preclinical in vitro and in vivo evaluation of sodium channel blockers as possible alternative to mexiletine in the treatment of myotonia 57
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Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 55
Molecular determinants of human voltage-gated sodium channel blockade by lubeluzole 54
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 53
Derivati idrossilati della mexiletina come tools farmacologici nello studio dell'attività di blocco dei canali sodici 53
Covid-19, chloroquine repurposing, and cardiac safety concern: Chirality might help 53
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 53
Novel lysophosphatidic acid receptor 6 antagonists inhibit hepatocellular carcinoma growth through affecting mitochondrial function 52
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 51
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 51
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 50
Sintesi enantiospecifica one-step di acidi O-aril ed O-eteroaril mandelici, utilizzabili come agenti di solvatazione chirale 48
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 48
Targeting the pregnane X receptor using microbial metabolite mimicry 47
Separation and quantitative determination of mexiletine and its metabolites by capillary zone electrophoresis 45
Pilsicainide and its oxymethylene analog: Facile alternative synthesis and in vitro testing on human skeletal muscle sodium channels 45
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 44
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 43
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 41
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 41
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 40
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 40
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 39
Design of a pharmacological rat model of myotonia congenita for antimyotonic drug screening 38
Sintesi alternativa del lubeluzolo e del suo enantiomero e valutazione come agenti in grado di potenziare l'effetto di farmaci antitumorali. 38
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 37
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interaction at the main binding sites 36
Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials 36
Erratum: Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+ Channels 35
Efficient Routes to Lubeluzole, Its Enantiomer, and Racemate 34
Dual-Acting Drugs: Antioxidant Activity of Voltage-Gated Sodium Channel Blocking Agents Coupled to a Pyrroline Moiety 33
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 33
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela ottimale 30
Voltage-gated sodium channel blocking agents coupled to a ros scavenging pyrroline moiety as dual-acting twin drugs 30
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 30
Label-free, reagentless, straightforward capillary electrophoretic method to individuate potent calmodulin ligands. 29
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 27
Sintesi della pilsicainide e valutazione della sua attività di blocco sui canali sodici di muscolo scheletrico umano 27
Small Molecules as MT1 And MT2 Ligands: Antioxidant Properties and in vitro Inhibition of Ca2+/CAM-Dependent Kinase II. 27
Dual-acting drugs: antioxidant activity of voltage-gated sodium channel blocking agents coupled to a pyrroline moiety. 27
First synthesis and full characterization of mexiletine N-carbonyloxy beta-D-glucuronide 26
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 25
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth 25
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 24
Preparation of Chiral 2-(9-Anthryl)Alcanoic Acids, 9-Xanthenyl Isosteres, and Derivatives 23
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies 23
Phyllostachys Pubescens: From Traditional to Functional Food: Phyllostachys pubescens as functional food 23
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela di eluizione ottimale 22
Label-free, Reagentless, Straightforward Capillary Electrophoretic Method to Individuate Potent Calmodulin Ligands 22
The Crystal Structure of N-[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl]-4-methoxy-N-methylbenzenesulfonamide 22
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela di eluizione ottimale 21
Small molecules as MT1 and MT2 ligands: antioxidant properties and in vitro inhibition of Ca2+/CaM-dependent kinase II. 21
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 21
Targeting Penicillium expansum GMC oxidoreductase with high affinity small molecules for reducing patulin production 18
Separation and quantitative determination of mexiletine by capillary zone electrophoresis 16
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 14
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 13
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 9
Lubeluzole Repositioning as Chemosensitizing Agent on Multidrug-Resistant Human Ovarian A2780/DX3 Cancer Cells 8
Totale 5.428
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Categoria #
all - tutte 22.643
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.643
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019310 0 0 0 0 0 0 0 0 0 0 157 153
2019/20201.278 230 75 30 108 123 64 114 90 173 76 160 35
2020/2021990 198 49 72 65 76 39 77 64 84 125 84 57
2021/2022727 41 113 29 27 5 48 29 29 51 43 112 200
2022/20231.189 170 131 66 96 122 157 17 159 182 17 47 25
2023/2024441 31 78 27 59 32 125 9 31 19 30 0 0
Totale 5.475