IRIS
CAVALLUZZI, MARIA MADDALENA
 Distribuzione geografica
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Continente #
NA - Nord America 4.352
EU - Europa 1.601
AS - Asia 1.297
SA - Sud America 350
AF - Africa 21
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.629
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Nazione #
US - Stati Uniti d'America 4.292
CN - Cina 406
IT - Italia 376
SG - Singapore 352
BR - Brasile 309
HK - Hong Kong 302
RU - Federazione Russa 300
SE - Svezia 295
DE - Germania 148
UA - Ucraina 115
FI - Finlandia 103
GB - Regno Unito 92
FR - Francia 65
IN - India 46
TR - Turchia 44
CA - Canada 41
BD - Bangladesh 25
ID - Indonesia 25
BE - Belgio 24
VN - Vietnam 23
CO - Colombia 17
AT - Austria 12
IE - Irlanda 12
MX - Messico 12
NL - Olanda 12
IQ - Iraq 10
JP - Giappone 10
PK - Pakistan 9
PL - Polonia 9
ZA - Sudafrica 9
ES - Italia 8
LT - Lituania 8
AR - Argentina 7
AU - Australia 6
MA - Marocco 6
SA - Arabia Saudita 6
CZ - Repubblica Ceca 5
IR - Iran 5
PH - Filippine 5
EC - Ecuador 4
EG - Egitto 4
KR - Corea 4
PT - Portogallo 4
UZ - Uzbekistan 4
PE - Perù 3
PY - Paraguay 3
RO - Romania 3
RS - Serbia 3
TH - Thailandia 3
TW - Taiwan 3
UY - Uruguay 3
BO - Bolivia 2
GE - Georgia 2
HU - Ungheria 2
KG - Kirghizistan 2
MY - Malesia 2
OM - Oman 2
PS - Palestinian Territory 2
TT - Trinidad e Tobago 2
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CH - Svizzera 1
CR - Costa Rica 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
EU - Europa 1
FK - Isole Falkland (Malvinas) 1
HR - Croazia 1
IL - Israele 1
JM - Giamaica 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
QA - Qatar 1
TN - Tunisia 1
VE - Venezuela 1
Totale 7.629
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Città #
Fairfield 535
Chandler 400
Woodbridge 321
Ashburn 307
Hong Kong 298
Houston 268
Jacksonville 262
Nyköping 240
Seattle 235
Singapore 233
Cambridge 198
Ann Arbor 178
Wilmington 178
Bari 142
New York 91
Lawrence 90
Roxbury 89
Beijing 76
Nanjing 72
Des Moines 56
Princeton 56
Boardman 46
Munich 45
Los Angeles 41
Moscow 39
Brooklyn 36
Inglewood 30
London 29
San Diego 29
Helsinki 26
Jakarta 25
Santa Clara 25
Brussels 23
Jiaxing 22
Guangzhou 21
Toronto 19
Rome 18
San Francisco 18
Shenyang 17
Council Bluffs 15
Hebei 15
Paris 15
Istanbul 14
São Paulo 14
Dearborn 13
Dong Ket 13
Nanchang 13
Rio de Janeiro 13
The Dalles 13
Columbus 12
Dublin 12
Pune 12
Tianjin 12
Changsha 11
Milan 11
Dhaka 10
Frankfurt am Main 10
Marseille 10
Nuremberg 10
Wuhan 10
North Bergen 9
Porto Alegre 9
Turku 9
Leawood 8
Medellín 8
Redwood City 8
Shanghai 8
Belo Horizonte 7
Brescia 6
Chennai 6
Chicago 6
Falkenstein 6
Guarulhos 6
Jinan 6
Montreal 6
Mumbai 6
Norwalk 6
Salvador 6
San Mateo 6
Tokyo 6
Triggiano 6
Vienna 6
Washington 6
Ankara 5
Dallas 5
Faisalabad 5
Grottaglie 5
Hefei 5
Kilburn 5
Phoenix 5
Portsmouth 5
Stockholm 5
Warsaw 5
Zhengzhou 5
Belém 4
Bitonto 4
Bogotá 4
Bologna 4
Brasília 4
Campinas 4
Totale 5.327
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Nome #
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 143
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 139
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 135
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 132
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 130
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 129
The chemistry and pharmacology of citrus limonoids 127
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 123
Recent trends in the discovery of small molecule blockers of sodium channels 120
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 120
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 119
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 119
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 118
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 118
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 116
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 115
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 115
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 110
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 104
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 104
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 103
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 99
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 96
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 96
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 94
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 93
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 91
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Discovery of a new mexiletine-derived agonist of the hERG K+channel 91
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 91
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 89
2-(9-Antryl)alcanoic acids as chloride channel modulators 89
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 87
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 87
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 85
Lubeluzole: from anti-ischemic to chemosensitizing agent 82
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 81
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 80
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 79
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole 77
Targeting the pregnane X receptor using microbial metabolite mimicry 77
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 77
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 76
Covid-19, chloroquine repurposing, and cardiac safety concern: Chirality might help 75
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 73
Novel lysophosphatidic acid receptor 6 antagonists inhibit hepatocellular carcinoma growth through affecting mitochondrial function 73
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 73
Synthesis of (R)-, (S)-, and (RS)-hydroxymethylmexiletine one of the major metabolites of mexiletine 72
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 71
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 71
Derivati idrossilati della mexiletina come tools farmacologici nello studio dell'attività di blocco dei canali sodici 71
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 70
Pilsicainide and its oxymethylene analog: Facile alternative synthesis and in vitro testing on human skeletal muscle sodium channels 70
Preclinical in vitro and in vivo evaluation of sodium channel blockers as possible alternative to mexiletine in the treatment of myotonia 69
Molecular determinants of human voltage-gated sodium channel blockade by lubeluzole 67
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Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 63
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 63
Sintesi enantiospecifica one-step di acidi O-aril ed O-eteroaril mandelici, utilizzabili come agenti di solvatazione chirale 62
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 61
Separation and quantitative determination of mexiletine and its metabolites by capillary zone electrophoresis 59
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 57
Sintesi alternativa del lubeluzolo e del suo enantiomero e valutazione come agenti in grado di potenziare l'effetto di farmaci antitumorali. 57
Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials 57
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 56
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 56
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Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 56
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 54
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth 51
Design of a pharmacological rat model of myotonia congenita for antimyotonic drug screening 50
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 49
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 49
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 49
Voltage-gated sodium channel blocking agents coupled to a ros scavenging pyrroline moiety as dual-acting twin drugs 48
Efficient Routes to Lubeluzole, Its Enantiomer, and Racemate 48
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies 48
Erratum: Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+ Channels 48
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 48
The Crystal Structure of N-[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl]-4-methoxy-N-methylbenzenesulfonamide 48
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 47
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela ottimale 46
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interaction at the main binding sites 45
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 44
Biostimulant Formulations and Moringa oleifera Extracts to Improve Yield, Quality, and Storability of Hydroponic Lettuce 44
Label-free, reagentless, straightforward capillary electrophoretic method to individuate potent calmodulin ligands. 44
Phyllostachys Pubescens: From Traditional to Functional Food: Phyllostachys pubescens as functional food 44
Dual-Acting Drugs: Antioxidant Activity of Voltage-Gated Sodium Channel Blocking Agents Coupled to a Pyrroline Moiety 43
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 43
Targeting Penicillium expansum GMC oxidoreductase with high affinity small molecules for reducing patulin production 43
Small molecules as MT1 and MT2 ligands: antioxidant properties and in vitro inhibition of Ca2+/CaM-dependent kinase II. 42
Inhibition of lysophosphatidic acid receptor 6 upregulated by the choline-deficient l-amino acid-defined diet prevents hepatocarcinogenesis in mice 40
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 40
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 40
Sintesi della pilsicainide e valutazione della sua attività di blocco sui canali sodici di muscolo scheletrico umano 39
Small Molecules as MT1 And MT2 Ligands: Antioxidant Properties and in vitro Inhibition of Ca2+/CAM-Dependent Kinase II. 38
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels 37
Dual-acting drugs: antioxidant activity of voltage-gated sodium channel blocking agents coupled to a pyrroline moiety. 37
Preparation of Chiral 2-(9-Anthryl)Alcanoic Acids, 9-Xanthenyl Isosteres, and Derivatives 37
Totale 7.509
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Categoria #
all - tutte 36.985
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.985
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021990 198 49 72 65 76 39 77 64 84 125 84 57
2021/2022727 41 113 29 27 5 48 29 29 51 43 112 200
2022/20231.189 170 131 66 96 122 157 17 159 182 17 47 25
2023/2024558 31 78 27 59 32 125 9 31 19 30 50 67
2024/20252.180 93 40 165 65 60 186 253 248 107 112 305 546
2025/2026252 252 0 0 0 0 0 0 0 0 0 0 0
Totale 8.024