IRIS
CAVALLUZZI, MARIA MADDALENA
 Distribuzione geografica
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Continente #
NA - Nord America 5.974
AS - Asia 2.970
EU - Europa 2.166
SA - Sud America 643
AF - Africa 169
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.936
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Nazione #
US - Stati Uniti d'America 5.848
SG - Singapore 1.208
CN - Cina 636
IT - Italia 525
BR - Brasile 484
HK - Hong Kong 370
RU - Federazione Russa 309
SE - Svezia 303
FI - Finlandia 197
DE - Germania 185
VN - Vietnam 182
FR - Francia 171
GB - Regno Unito 147
UA - Ucraina 123
IN - India 110
TR - Turchia 80
BD - Bangladesh 69
CA - Canada 69
CI - Costa d'Avorio 63
ID - Indonesia 48
JP - Giappone 45
AR - Argentina 44
ZA - Sudafrica 39
MX - Messico 35
PK - Pakistan 34
CO - Colombia 32
IQ - Iraq 31
PL - Polonia 29
ES - Italia 28
NL - Olanda 27
BE - Belgio 24
PH - Filippine 23
AT - Austria 19
EC - Ecuador 18
MA - Marocco 18
VE - Venezuela 18
MY - Malesia 17
SA - Arabia Saudita 16
TH - Thailandia 16
IE - Irlanda 15
UY - Uruguay 12
EG - Egitto 11
LT - Lituania 11
AU - Australia 10
PE - Perù 10
UZ - Uzbekistan 10
BO - Bolivia 9
KE - Kenya 9
KR - Corea 9
RO - Romania 9
KG - Kirghizistan 8
PY - Paraguay 8
AE - Emirati Arabi Uniti 7
AZ - Azerbaigian 7
CL - Cile 7
PT - Portogallo 7
CZ - Repubblica Ceca 6
JO - Giordania 6
TN - Tunisia 6
CR - Costa Rica 5
IR - Iran 5
PA - Panama 5
PS - Palestinian Territory 5
SI - Slovenia 5
DO - Repubblica Dominicana 4
ET - Etiopia 4
IL - Israele 4
JM - Giamaica 4
LY - Libia 4
NP - Nepal 4
RS - Serbia 4
TW - Taiwan 4
DZ - Algeria 3
GE - Georgia 3
HR - Croazia 3
SN - Senegal 3
AL - Albania 2
BY - Bielorussia 2
CG - Congo 2
CY - Cipro 2
DK - Danimarca 2
HU - Ungheria 2
KW - Kuwait 2
LB - Libano 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BZ - Belize 1
CD - Congo 1
CH - Svizzera 1
EE - Estonia 1
EU - Europa 1
Totale 11.923
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Città #
Singapore 667
Ashburn 631
Fairfield 535
Chandler 394
San Jose 392
Hong Kong 365
Woodbridge 321
Houston 275
Jacksonville 262
Seattle 238
Nyköping 233
Dallas 227
Cambridge 198
Beijing 184
Wilmington 182
Ann Arbor 178
Bari 157
New York 133
Helsinki 118
Los Angeles 117
Lauterbourg 103
Roxbury 89
Lawrence 88
Nanjing 72
Abidjan 63
Council Bluffs 59
Des Moines 56
Princeton 54
Brooklyn 49
Ho Chi Minh City 49
Boardman 47
Santa Clara 47
Munich 45
São Paulo 42
Tokyo 40
London 38
Moscow 38
Hanoi 36
Chicago 31
Jakarta 31
Inglewood 30
San Diego 29
Buffalo 26
Guangzhou 25
Warsaw 25
Brussels 23
Falkenstein 23
Jiaxing 23
Rome 23
Toronto 23
Frankfurt am Main 22
Istanbul 22
Johannesburg 22
Chennai 21
Denver 20
Stockholm 20
Orem 19
San Francisco 19
Dhaka 17
Montreal 17
Shenyang 17
Paris 16
Phoenix 16
Rio de Janeiro 16
Atlanta 15
Dublin 15
Hebei 15
Milan 15
Medellín 14
Poplar 14
Baghdad 13
Changsha 13
Dearborn 13
Dong Ket 13
Mexico City 13
Nanchang 13
Nuremberg 13
Porto Alegre 13
The Dalles 13
Tianjin 13
Ankara 12
Columbus 12
Lahore 12
Manchester 12
Pune 12
Amsterdam 11
Mumbai 11
Wuhan 11
Marseille 10
Shanghai 10
Turku 10
Bangkok 9
Fragagnano 9
Montevideo 9
North Bergen 9
Salvador 9
Sannicandro di Bari 9
Belo Horizonte 8
Da Nang 8
Kuala Lumpur 8
Totale 7.817
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Nome #
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 228
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 207
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 205
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 199
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 180
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 178
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 178
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 173
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 170
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 165
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 164
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 163
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 160
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 160
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 159
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 156
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 156
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 155
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 154
The chemistry and pharmacology of citrus limonoids 153
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 153
Hypoglycemic properties of Leccinum scabrum - An in vitro study on α-glucosidase and α-amylase inhibition activity 149
2-(9-Antryl)alcanoic acids as chloride channel modulators 149
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 146
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 146
Recent trends in the discovery of small molecule blockers of sodium channels 142
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 141
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 139
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 139
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 136
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 132
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 126
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 126
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 122
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 120
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 118
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 117
Targeting the pregnane X receptor using microbial metabolite mimicry 116
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 115
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 115
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 113
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 113
Lubeluzole: from anti-ischemic to chemosensitizing agent 113
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 110
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 108
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 108
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 107
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 107
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole 104
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 104
Biostimulant Formulations and Moringa oleifera Extracts to Improve Yield, Quality, and Storability of Hydroponic Lettuce 102
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 102
Discovery of a new mexiletine-derived agonist of the hERG K+channel 101
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 101
Covid-19, chloroquine repurposing, and cardiac safety concern: Chirality might help 100
The Crystal Structure of N-[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl]-4-methoxy-N-methylbenzenesulfonamide 100
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 99
Novel lysophosphatidic acid receptor 6 antagonists inhibit hepatocellular carcinoma growth through affecting mitochondrial function 96
Preclinical in vitro and in vivo evaluation of sodium channel blockers as possible alternative to mexiletine in the treatment of myotonia 92
Pilsicainide and its oxymethylene analog: Facile alternative synthesis and in vitro testing on human skeletal muscle sodium channels 92
Targeting Penicillium expansum GMC oxidoreductase with high affinity small molecules for reducing patulin production 92
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 90
Derivati idrossilati della mexiletina come tools farmacologici nello studio dell'attività di blocco dei canali sodici 90
Sintesi alternativa del lubeluzolo e del suo enantiomero e valutazione come agenti in grado di potenziare l'effetto di farmaci antitumorali. 90
A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli 89
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth 88
Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials 87
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 87
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 85
Synthesis of (R)-, (S)-, and (RS)-hydroxymethylmexiletine one of the major metabolites of mexiletine 85
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 84
Molecular determinants of human voltage-gated sodium channel blockade by lubeluzole 84
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 84
Antiviral Properties of Moringa oleifera Leaf Extracts against Respiratory Viruses 84
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies 83
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 82
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels 80
Lactoferrin-derived peptides as a control strategy against skinborne staphylococcal biofilms 79
Inhibition of lysophosphatidic acid receptor 6 upregulated by the choline-deficient l-amino acid-defined diet prevents hepatocarcinogenesis in mice 77
Phyllostachys Pubescens: From Traditional to Functional Food: Phyllostachys pubescens as functional food 77
Sintesi enantiospecifica one-step di acidi O-aril ed O-eteroaril mandelici, utilizzabili come agenti di solvatazione chirale 76
Microwave-assisted extraction and medicinal mushrooms: an innovative and promising technique with significant applicative implications 76
Lentil Waste Extracts for Inflammatory Bowel Disease (IBD) Symptoms Control: Anti-Inflammatory and Spasmolytic Effects 75
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 75
Separation and quantitative determination of mexiletine and its metabolites by capillary zone electrophoresis 74
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 73
Drug Repositioning for Ovarian Cancer Treatment: An Update 72
Targeting Penicillium expansum transporters with high affinity small molecules for reducing patulin production 71
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 70
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents 70
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 66
Label-free, Reagentless, Straightforward Capillary Electrophoretic Method to Individuate Potent Calmodulin Ligands 66
Preparation of Chiral 2-(9-Anthryl)Alcanoic Acids, 9-Xanthenyl Isosteres, and Derivatives 66
Voltage-gated sodium channel blocking agents coupled to a ros scavenging pyrroline moiety as dual-acting twin drugs 65
null 65
Erratum: Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+ Channels 64
Design of a pharmacological rat model of myotonia congenita for antimyotonic drug screening 62
Hypoglycemic Properties of Leccinum scabrum Extracts—An In Vitro Study on α-Glucosidase and α-Amylase Inhibition and Metabolic Profile Determination 61
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela ottimale 61
Efficient Routes to Lubeluzole, Its Enantiomer, and Racemate 61
Totale 11.248
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Categoria #
all - tutte 48.713
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.713
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021266 0 0 0 0 0 0 0 0 0 125 84 57
2021/2022727 41 113 29 27 5 48 29 29 51 43 112 200
2022/20231.168 166 128 64 94 120 154 17 156 180 17 47 25
2023/2024551 31 77 27 58 32 121 9 31 19 29 50 67
2024/20252.143 92 39 163 65 59 184 248 245 106 109 298 535
2025/20264.634 661 223 490 526 632 367 665 134 525 411 0 0
Totale 12.341