IRIS
CAVALLUZZI, MARIA MADDALENA
 Distribuzione geografica
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Continente #
NA - Nord America 5.273
AS - Asia 2.362
EU - Europa 1.782
SA - Sud America 493
AF - Africa 114
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 10.035
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Nazione #
US - Stati Uniti d'America 5.177
SG - Singapore 1.004
CN - Cina 580
IT - Italia 426
BR - Brasile 415
HK - Hong Kong 332
RU - Federazione Russa 301
SE - Svezia 300
DE - Germania 153
GB - Regno Unito 139
UA - Ucraina 118
VN - Vietnam 117
FI - Finlandia 106
IN - India 66
FR - Francia 63
CI - Costa d'Avorio 62
CA - Canada 61
TR - Turchia 53
ID - Indonesia 40
JP - Giappone 33
BD - Bangladesh 30
PL - Polonia 29
BE - Belgio 24
ES - Italia 24
MX - Messico 24
ZA - Sudafrica 23
AR - Argentina 22
CO - Colombia 22
NL - Olanda 20
AT - Austria 18
IQ - Iraq 12
MA - Marocco 12
IE - Irlanda 11
PK - Pakistan 11
TH - Thailandia 11
LT - Lituania 10
EC - Ecuador 9
PH - Filippine 9
RO - Romania 9
AU - Australia 8
EG - Egitto 8
KR - Corea 7
UY - Uruguay 7
AE - Emirati Arabi Uniti 6
PE - Perù 6
SA - Arabia Saudita 6
CZ - Repubblica Ceca 5
IR - Iran 5
MY - Malesia 5
PY - Paraguay 5
SI - Slovenia 5
IL - Israele 4
KG - Kirghizistan 4
PS - Palestinian Territory 4
PT - Portogallo 4
TW - Taiwan 4
UZ - Uzbekistan 4
BO - Bolivia 3
HR - Croazia 3
JO - Giordania 3
RS - Serbia 3
VE - Venezuela 3
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
GE - Georgia 2
HU - Ungheria 2
JM - Giamaica 2
KE - Kenya 2
NG - Nigeria 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BY - Bielorussia 1
BZ - Belize 1
CH - Svizzera 1
CY - Cipro 1
EE - Estonia 1
EU - Europa 1
FK - Isole Falkland (Malvinas) 1
KH - Cambogia 1
LB - Libano 1
MK - Macedonia 1
MW - Malawi 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PA - Panama 1
QA - Qatar 1
SN - Senegal 1
TL - Timor Orientale 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 10.035
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Città #
Ashburn 568
Fairfield 535
Singapore 529
Chandler 394
Hong Kong 328
Woodbridge 321
Houston 273
Jacksonville 262
Seattle 238
Nyköping 233
Dallas 224
Cambridge 198
Wilmington 181
Ann Arbor 178
Beijing 173
Bari 146
New York 126
Los Angeles 112
Roxbury 89
Lawrence 88
Nanjing 72
Abidjan 62
Des Moines 56
Princeton 54
Brooklyn 48
Boardman 45
Munich 45
Santa Clara 39
London 38
Moscow 38
São Paulo 34
Ho Chi Minh City 32
Jakarta 31
Inglewood 30
San Diego 29
Tokyo 29
Chicago 28
Hanoi 27
Helsinki 27
Warsaw 25
Guangzhou 24
Brussels 23
Buffalo 23
Jiaxing 23
Toronto 23
Rome 18
San Francisco 18
Council Bluffs 17
Shenyang 17
Stockholm 17
Chennai 16
Denver 16
Hebei 15
Istanbul 15
Johannesburg 15
Paris 15
Phoenix 15
Montreal 14
Dearborn 13
Dong Ket 13
Milan 13
Nanchang 13
Nuremberg 13
Poplar 13
Rio de Janeiro 13
The Dalles 13
Tianjin 13
Changsha 12
Columbus 12
Porto Alegre 12
Pune 12
Atlanta 11
Dublin 11
Frankfurt am Main 11
Orem 11
Wuhan 11
Ankara 10
Dhaka 10
Manchester 10
Marseille 10
Turku 10
Fragagnano 9
Medellín 9
North Bergen 9
Shanghai 9
Leawood 8
Mexico City 8
Redwood City 8
Amsterdam 7
Belo Horizonte 7
Charlotte 7
Curitiba 7
Da Nang 7
Guarulhos 7
Mumbai 7
Salvador 7
Triggiano 7
Boston 6
Brasília 6
Brescia 6
Totale 6.720
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Nome #
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 193
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 192
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 190
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 168
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 162
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 156
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 152
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 152
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 150
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 149
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 148
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 142
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 140
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 137
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 137
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 136
The chemistry and pharmacology of citrus limonoids 136
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 136
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 135
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 133
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 133
Recent trends in the discovery of small molecule blockers of sodium channels 131
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 131
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 125
2-(9-Antryl)alcanoic acids as chloride channel modulators 124
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 124
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 121
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 120
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 115
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 112
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 112
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 105
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 105
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 105
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 102
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 100
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 99
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 98
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 98
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 98
Discovery of a new mexiletine-derived agonist of the hERG K+channel 96
Hypoglycemic properties of Leccinum scabrum - An in vitro study on α-glucosidase and α-amylase inhibition activity 95
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 95
Lubeluzole: from anti-ischemic to chemosensitizing agent 95
New N-(phenoxydecyl)phthalimide derivatives displaying potent inhibition activity towards alpha-glucosidase 93
Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials 91
Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole 90
Novel lysophosphatidic acid receptor 6 antagonists inhibit hepatocellular carcinoma growth through affecting mitochondrial function 87
Targeting the pregnane X receptor using microbial metabolite mimicry 87
Covid-19, chloroquine repurposing, and cardiac safety concern: Chirality might help 86
The Crystal Structure of N-[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl]-4-methoxy-N-methylbenzenesulfonamide 86
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 85
Preclinical in vitro and in vivo evaluation of sodium channel blockers as possible alternative to mexiletine in the treatment of myotonia 82
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 82
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 81
Pilsicainide and its oxymethylene analog: Facile alternative synthesis and in vitro testing on human skeletal muscle sodium channels 81
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 80
Sintesi alternativa del lubeluzolo e del suo enantiomero e valutazione come agenti in grado di potenziare l'effetto di farmaci antitumorali. 80
Derivati idrossilati della mexiletina come tools farmacologici nello studio dell'attività di blocco dei canali sodici 79
Synthesis of (R)-, (S)-, and (RS)-hydroxymethylmexiletine one of the major metabolites of mexiletine 78
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 78
Biostimulant Formulations and Moringa oleifera Extracts to Improve Yield, Quality, and Storability of Hydroponic Lettuce 76
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 75
Evaluation of the dual action of new derivatives of mexiletine as use-dependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 75
Molecular determinants of human voltage-gated sodium channel blockade by lubeluzole 74
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 73
Densely Functionalized 2-Methylideneazetidines: Evaluation as Antibacterials 72
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth 71
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 70
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies 70
Sintesi enantiospecifica one-step di acidi O-aril ed O-eteroaril mandelici, utilizzabili come agenti di solvatazione chirale 67
Separation and quantitative determination of mexiletine and its metabolites by capillary zone electrophoresis 67
Evaluation of the dual action of new derivatives of mexiletine as usedependent sodium channel blockers and antioxidant: potential therapeutic application in neuromuscular disorders 66
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 66
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 66
A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli 65
null 65
Targeting Penicillium expansum GMC oxidoreductase with high affinity small molecules for reducing patulin production 64
Metabolic derivatives of antiarrhythmic drugs: stereospecific synthesis of N-hydroxymexiletine and meta-hydroxymexiletine 63
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels 62
Separazione e determinazione quantitativa dei principali prodotti di degradazione metabolica e chimica della mexiletina mediante elettroforesi capillare zonale 61
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents 61
Inhibition of lysophosphatidic acid receptor 6 upregulated by the choline-deficient l-amino acid-defined diet prevents hepatocarcinogenesis in mice 60
Phyllostachys Pubescens: From Traditional to Functional Food: Phyllostachys pubescens as functional food 59
Voltage-gated sodium channel blocking agents coupled to a ros scavenging pyrroline moiety as dual-acting twin drugs 58
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 58
Preparation of Chiral 2-(9-Anthryl)Alcanoic Acids, 9-Xanthenyl Isosteres, and Derivatives 58
Lactoferrin-derived peptides as a control strategy against skinborne staphylococcal biofilms 57
Design of a pharmacological rat model of myotonia congenita for antimyotonic drug screening 57
null 56
Lentil Waste Extracts for Inflammatory Bowel Disease (IBD) Symptoms Control: Anti-Inflammatory and Spasmolytic Effects 55
Efficient Routes to Lubeluzole, Its Enantiomer, and Racemate 55
Microwave-assisted extraction and medicinal mushrooms: an innovative and promising technique with significant applicative implications 55
Drug Repositioning for Ovarian Cancer Treatment: An Update 54
Label-free, Reagentless, Straightforward Capillary Electrophoretic Method to Individuate Potent Calmodulin Ligands 53
Riconoscimento degli alogenuri mediante cromatografia su carta: disegno sperimentale (DoE) applicato alla individuazione della miscela ottimale 52
Dual-Acting Drugs: Antioxidant Activity of Voltage-Gated Sodium Channel Blocking Agents Coupled to a Pyrroline Moiety 52
Small molecules as MT1 and MT2 ligands: antioxidant properties and in vitro inhibition of Ca2+/CaM-dependent kinase II. 52
Erratum: Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+ Channels 52
Totale 9.585
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Categoria #
all - tutte 45.311
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.311
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021530 0 0 0 0 0 39 77 64 84 125 84 57
2021/2022727 41 113 29 27 5 48 29 29 51 43 112 200
2022/20231.168 166 128 64 94 120 154 17 156 180 17 47 25
2023/2024551 31 77 27 58 32 121 9 31 19 29 50 67
2024/20252.143 92 39 163 65 59 184 248 245 106 109 298 535
2025/20262.730 661 223 490 526 632 198 0 0 0 0 0 0
Totale 10.437