SPORTELLI, LEONARDO
SPORTELLI, LEONARDO
A miR-137-related biological pathway of risk for Schizophrenia is associated with human brain emotion processing
2024-01-01 Pergola, Giulio; Rampino, Antonio; Sportelli, Leonardo; Borcuk, Christopher James; Passiatore, Roberta; Di Carlo, Pasquale; Marakhovskaia, Aleksandra; Fazio, Leonardo; Amoroso, Nicola; Castro, Mariana Nair; Domenici, Enrico; Gennarelli, Massimo; Khlghatyan, Jivan; Kikidis, Gianluca Christos; Lella, Annalisa; Magri, Chiara; Monaco, Alfonso; Papalino, Marco; Parihar, Madhur; Popolizio, Teresa; Quarto, Tiziana; Romano, Raffaella; Torretta, Silvia; Valsecchi, Paolo; Zunuer, Hediche; Blasi, Giuseppe; Dukart, Juergen; Beaulieu, Jean Martin; Bertolino, Alessandro
A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function
2022-01-01 D'Ambrosio, Enrico; Pergola, Giulio; Pardiñas, Antonio F; Dahoun, Tarik; Veronese, Mattia; Sportelli, Leonardo; Taurisano, Paolo; Griffiths, Kira; Jauhar, Sameer; Rogdaki, Maria; Bloomfield, Michael A P; Froudist-Walsh, Sean; Bonoldi, Ilaria; Walters, James T R; Blasi, Giuseppe; Bertolino, Alessandro; Howes, Oliver D
Changes in patterns of age-related network connectivity are associated with risk for schizophrenia
2023-01-01 Passiatore, Roberta; Antonucci, Linda A; Deramus, Thomas P; Fazio, Leonardo; Stolfa, Giuseppe; Sportelli, Leonardo; Kikidis, Gianluca C; Blasi, Giuseppe; Chen, Qiang; Dukart, Juergen; Goldman, Aaron L; Mattay, Venkata S; Popolizio, Teresa; Rampino, Antonio; Sambataro, Fabio; Selvaggi, Pierluigi; Ulrich, William; Weinberger, Daniel R; Bertolino, Alessandro; Calhoun, Vince D; Pergola, Giulio
Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions
2023-01-01 Pergola, Giulio; Parihar, Madhur; Sportelli, Leonardo; Bharadwaj, Rahul; Borcuk, Christopher James; Radulescu, Eugenia; Bellantuono, Loredana; Blasi, Giuseppe; Chen, Qiang; Kleinman, Joel E.; Wang, Yanhong; Rao Sripathy, Srinidhi; Maher, Brady J.; Monaco, Alfonso; Rossi, Fabiana; Heon Shin, Joo; Hyde, Thomas M.; Bertolino, Alessandro; Weinberger, Daniel R.
Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function
2023-01-01 Sportelli, Leonardo; Eisenberg, Daniel P; Passiatore, Roberta; D'Ambrosio, Enrico; Antonucci, Linda A; Chen, Qiang; Czarapata, Jasmine; Goldman, Aaron L; Gregory, Michael; Griffiths, Kira; Hyde, Thomas M; Kleinman, Joel E; Pardiñas, Antonio F; Parihar, Madhur; Popolizio, Teresa; Rampino, Antonio; Shin, Joo Heon; Veronese, Mattia; Ulrich, William S; Zink, Caroline F; Bertolino, Alessandro; Howes, Oliver D; Berman, Karen F; Weinberger, Daniel R; Pergola, Giulio
Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo
2024-01-01 Sportelli, Leonardo; Eisenberg, Daniel P.; Passiatore, Roberta; D’Ambrosio, Enrico; Antonucci, Linda A.; Bettina, Jasmine S.; Chen, Qiang; Goldman, Aaron L.; Gregory, Michael D.; Griffiths, Kira; Hyde, Thomas M.; Kleinman, Joel E.; Pardiñas, Antonio F.; Parihar, Madhur; Popolizio, Teresa; Rampino, Antonio; Shin, Joo Heon; Veronese, Mattia; Ulrich, William S.; Zink, Caroline F.; Bertolino, Alessandro; Howes, Oliver D.; Berman, Karen F.; Weinberger, Daniel R.; Pergola, Giulio
Dorsolateral Prefrontal Cortex Single Nuclei Tensor Decomposition Identifies Shared Genetic Risk for Major Depressive Disorder and Schizophrenia in Suicidal Subjects
2021-01-01 Sportelli, Leonardo; Nagy, Corina; Theroux, Jean-Francois; Weinberger, Daniel; Turecki, Gustavo; Pergola, Giulio
ENHANCING GENE EXPRESSION PREDICTION IN MAJOR PSYCHIATRIC DISORDERS VIA CO-EXPRESSION MODELS
2023-01-01 Rossi, Fabiana; Kikidis, Gianluca C.; Parihar, Madhur; Blasi, Giuseppe; Rampino, Antonio; Bellantuono, Loredana; Sportelli, Leonardo; Kleinman, Joel E.; Penzel, Nora; Shin, Joo Heon; Hyde, Thomas M.; Weinberger, Daniel; Pergola, Giulio
Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics
2021-01-01 Rampino, Antonio; Torretta, Silvia; Gelao, Barbara; Veneziani, Federica; Iacoviello, Matteo; Marakhovskaya B, Aleksandra; Masellis, Rita; Andriola, Ileana; Sportelli, Leonardo; Pergola, Giulio; Minelli, Alessandra; Magri, Chiara; Gennarelli, Massimo; Vita, Antonio; Beaulieu, Jean Martin; Bertolino, Alessandro; Blasi, Giuseppe
GENE CONNECTIVITY ANALYSIS OF CO-EXPRESSION NETWORKS PROVIDES INSIGHTS INTO THE OMNIGENIC MODEL AND IDENTIFIES NOVEL GENETIC HUBS OF SCHIZOPHRENIA RISK
2022-01-01 Borcuk, Christopher; Parihar, Madhur; Sportelli, Leonardo; Kleinman, Joel E.; Shin, Joo Heon; Hyde, Thomas M.; Bertolino, Alessandro; Weinberger, Daniel R.; Pergola, Giulio
Lessons Learned From Parsing Genetic Risk for Schizophrenia Into Biological Pathways
2022-01-01 Pergola, Giulio; Penzel, Nora; Sportelli, Leonardo; Bertolino, Alessandro
Prefrontal Co-Expression of miR-137 Target Genes is Related With Prefrontal Activity During Emotion Recognition
2019-01-01 Rampino, Antonio; Pergola, Giulio; Di Carlo, Pasquale; Marakhovskaya, Aleksandra; Fazio, Leonardo; Papalino, Marco; Popolizio, Teresa; Quarto, Tiziana; Romano, Raffaella; Sportelli, Leonardo; Torretta, Silvia; Masellis, Rita; Zunuer, Hailiqiguli; Beaulieu, Jean-Martin; Blasi, Giuseppe; Bertolino, Alessandro
Prefrontal interneuron genes underlie neurobiological processes shared between psychiatric disorders
2022-01-01 Pergola, Giulio; Sportelli, Leonardo; Nagy, Corina; Weinberger, Daniel; Turecki, Gustavo
Schizophrenia Risk Genes Converge into Shifting Co-Expression Networks Across Brain Development, Ageing and Brain Regions
2022-01-01 Pergola, Giulio; Parihar, Madhur; Sportelli, Leonardo; Bharadwaj, Rahul; Radulescu, Eugenia; Blasi, Giuseppe; Chen, Qiang; Kleinman, Joel; Wang, Yanhong; Sripathy, Srinidhi Rao; Maher, Brady; Monaco, Alfonso; Shin, Joo Heon; Straub, Richard; Hyde, Thomas; Bertolino, Alessandro; Weinberger, Daniel
Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT
2024-01-01 Geraci, Federica; Passiatore, Roberta; Penzel, Nora; Laudani, Samuele; Bertolino, Alessandro; Blasi, Giuseppe; Graziano, Adriana C. E.; Kikidis, Gianluca C.; Mazza, Ciro; Parihar, Madhur; Rampino, Antonio; Sportelli, Leonardo; Trevisan, Nicolò; Drago, Filippo; Papaleo, Francesco; Sambataro, Fabio; Pergola, Giulio; Marco Leggio, Gian
Tensor-Based Decomposition Associates Striatal Gene Co-Expression With Increased Dopamine Signaling in Individuals at Genetic Risk for Schizophrenia
2022-01-01 Sportelli, Leonardo; Eisenberg, Daniel; D'Ambrosio, Enrico; Passiatore, Roberta; Bertolino, Alessandro; Chen, Qiang; Czarapata, Jasmine; Gregory, Michael; Griffiths, Kira; Hyde, Thomas; Kleinman, Joel; Pardinas, Antonio F.; Shin, Joo Heon; Veronese, Mattia; Zink, Caroline; Howes, Oliver; Berman, Karen; Weinberger, Daniel; Pergola, Giulio
The interaction between early life complications and a polygenic risk score for schizophrenia is associated with brain activity during emotion processing in healthy participants
2024-01-01 Toro, Veronica Debora; Antonucci, Linda A.; Quarto, Tiziana; Passiatore, Roberta; Fazio, Leonardo; Ursini, Gianluca; Chen, Qiang; Masellis, Rita; Torretta, Silvia; Sportelli, Leonardo; Kikidis, Gianluca Christos; Massari, Francesco; D'Ambrosio, Enrico; Rampino, Antonio; Pergola, Giulio; Weinberger, Daniel R.; Bertolino, Alessandro; Blasi, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A miR-137-related biological pathway of risk for Schizophrenia is associated with human brain emotion processing | 1-gen-2024 | Pergola, Giulio; Rampino, Antonio; Sportelli, Leonardo; Borcuk, Christopher James; Passiatore, Roberta; Di Carlo, Pasquale; Marakhovskaia, Aleksandra; Fazio, Leonardo; Amoroso, Nicola; Castro, Mariana Nair; Domenici, Enrico; Gennarelli, Massimo; Khlghatyan, Jivan; Kikidis, Gianluca Christos; Lella, Annalisa; Magri, Chiara; Monaco, Alfonso; Papalino, Marco; Parihar, Madhur; Popolizio, Teresa; Quarto, Tiziana; Romano, Raffaella; Torretta, Silvia; Valsecchi, Paolo; Zunuer, Hediche; Blasi, Giuseppe; Dukart, Juergen; Beaulieu, Jean Martin; Bertolino, Alessandro | |
| A polygenic score indexing a DRD2-related co-expression network is associated with striatal dopamine function | 1-gen-2022 | D'Ambrosio, Enrico; Pergola, Giulio; Pardiñas, Antonio F; Dahoun, Tarik; Veronese, Mattia; Sportelli, Leonardo; Taurisano, Paolo; Griffiths, Kira; Jauhar, Sameer; Rogdaki, Maria; Bloomfield, Michael A P; Froudist-Walsh, Sean; Bonoldi, Ilaria; Walters, James T R; Blasi, Giuseppe; Bertolino, Alessandro; Howes, Oliver D | |
| Changes in patterns of age-related network connectivity are associated with risk for schizophrenia | 1-gen-2023 | Passiatore, Roberta; Antonucci, Linda A; Deramus, Thomas P; Fazio, Leonardo; Stolfa, Giuseppe; Sportelli, Leonardo; Kikidis, Gianluca C; Blasi, Giuseppe; Chen, Qiang; Dukart, Juergen; Goldman, Aaron L; Mattay, Venkata S; Popolizio, Teresa; Rampino, Antonio; Sambataro, Fabio; Selvaggi, Pierluigi; Ulrich, William; Weinberger, Daniel R; Bertolino, Alessandro; Calhoun, Vince D; Pergola, Giulio | |
| Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions | 1-gen-2023 | Pergola, Giulio; Parihar, Madhur; Sportelli, Leonardo; Bharadwaj, Rahul; Borcuk, Christopher James; Radulescu, Eugenia; Bellantuono, Loredana; Blasi, Giuseppe; Chen, Qiang; Kleinman, Joel E.; Wang, Yanhong; Rao Sripathy, Srinidhi; Maher, Brady J.; Monaco, Alfonso; Rossi, Fabiana; Heon Shin, Joo; Hyde, Thomas M.; Bertolino, Alessandro; Weinberger, Daniel R. | |
| Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function | 1-gen-2023 | Sportelli, Leonardo; Eisenberg, Daniel P; Passiatore, Roberta; D'Ambrosio, Enrico; Antonucci, Linda A; Chen, Qiang; Czarapata, Jasmine; Goldman, Aaron L; Gregory, Michael; Griffiths, Kira; Hyde, Thomas M; Kleinman, Joel E; Pardiñas, Antonio F; Parihar, Madhur; Popolizio, Teresa; Rampino, Antonio; Shin, Joo Heon; Veronese, Mattia; Ulrich, William S; Zink, Caroline F; Bertolino, Alessandro; Howes, Oliver D; Berman, Karen F; Weinberger, Daniel R; Pergola, Giulio | |
| Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo | 1-gen-2024 | Sportelli, Leonardo; Eisenberg, Daniel P.; Passiatore, Roberta; D’Ambrosio, Enrico; Antonucci, Linda A.; Bettina, Jasmine S.; Chen, Qiang; Goldman, Aaron L.; Gregory, Michael D.; Griffiths, Kira; Hyde, Thomas M.; Kleinman, Joel E.; Pardiñas, Antonio F.; Parihar, Madhur; Popolizio, Teresa; Rampino, Antonio; Shin, Joo Heon; Veronese, Mattia; Ulrich, William S.; Zink, Caroline F.; Bertolino, Alessandro; Howes, Oliver D.; Berman, Karen F.; Weinberger, Daniel R.; Pergola, Giulio | |
| Dorsolateral Prefrontal Cortex Single Nuclei Tensor Decomposition Identifies Shared Genetic Risk for Major Depressive Disorder and Schizophrenia in Suicidal Subjects | 1-gen-2021 | Sportelli, Leonardo; Nagy, Corina; Theroux, Jean-Francois; Weinberger, Daniel; Turecki, Gustavo; Pergola, Giulio | |
| ENHANCING GENE EXPRESSION PREDICTION IN MAJOR PSYCHIATRIC DISORDERS VIA CO-EXPRESSION MODELS | 1-gen-2023 | Rossi, Fabiana; Kikidis, Gianluca C.; Parihar, Madhur; Blasi, Giuseppe; Rampino, Antonio; Bellantuono, Loredana; Sportelli, Leonardo; Kleinman, Joel E.; Penzel, Nora; Shin, Joo Heon; Hyde, Thomas M.; Weinberger, Daniel; Pergola, Giulio | |
| Evidence of an interaction between FXR1 and GSK3β polymorphisms on levels of Negative Symptoms of Schizophrenia and their response to antipsychotics | 1-gen-2021 | Rampino, Antonio; Torretta, Silvia; Gelao, Barbara; Veneziani, Federica; Iacoviello, Matteo; Marakhovskaya B, Aleksandra; Masellis, Rita; Andriola, Ileana; Sportelli, Leonardo; Pergola, Giulio; Minelli, Alessandra; Magri, Chiara; Gennarelli, Massimo; Vita, Antonio; Beaulieu, Jean Martin; Bertolino, Alessandro; Blasi, Giuseppe | |
| GENE CONNECTIVITY ANALYSIS OF CO-EXPRESSION NETWORKS PROVIDES INSIGHTS INTO THE OMNIGENIC MODEL AND IDENTIFIES NOVEL GENETIC HUBS OF SCHIZOPHRENIA RISK | 1-gen-2022 | Borcuk, Christopher; Parihar, Madhur; Sportelli, Leonardo; Kleinman, Joel E.; Shin, Joo Heon; Hyde, Thomas M.; Bertolino, Alessandro; Weinberger, Daniel R.; Pergola, Giulio | |
| Lessons Learned From Parsing Genetic Risk for Schizophrenia Into Biological Pathways | 1-gen-2022 | Pergola, Giulio; Penzel, Nora; Sportelli, Leonardo; Bertolino, Alessandro | |
| Prefrontal Co-Expression of miR-137 Target Genes is Related With Prefrontal Activity During Emotion Recognition | 1-gen-2019 | Rampino, Antonio; Pergola, Giulio; Di Carlo, Pasquale; Marakhovskaya, Aleksandra; Fazio, Leonardo; Papalino, Marco; Popolizio, Teresa; Quarto, Tiziana; Romano, Raffaella; Sportelli, Leonardo; Torretta, Silvia; Masellis, Rita; Zunuer, Hailiqiguli; Beaulieu, Jean-Martin; Blasi, Giuseppe; Bertolino, Alessandro | |
| Prefrontal interneuron genes underlie neurobiological processes shared between psychiatric disorders | 1-gen-2022 | Pergola, Giulio; Sportelli, Leonardo; Nagy, Corina; Weinberger, Daniel; Turecki, Gustavo | |
| Schizophrenia Risk Genes Converge into Shifting Co-Expression Networks Across Brain Development, Ageing and Brain Regions | 1-gen-2022 | Pergola, Giulio; Parihar, Madhur; Sportelli, Leonardo; Bharadwaj, Rahul; Radulescu, Eugenia; Blasi, Giuseppe; Chen, Qiang; Kleinman, Joel; Wang, Yanhong; Sripathy, Srinidhi Rao; Maher, Brady; Monaco, Alfonso; Shin, Joo Heon; Straub, Richard; Hyde, Thomas; Bertolino, Alessandro; Weinberger, Daniel | |
| Sex dimorphism controls dysbindin-related cognitive dysfunctions in mice and humans with the contribution of COMT | 1-gen-2024 | Geraci, Federica; Passiatore, Roberta; Penzel, Nora; Laudani, Samuele; Bertolino, Alessandro; Blasi, Giuseppe; Graziano, Adriana C. E.; Kikidis, Gianluca C.; Mazza, Ciro; Parihar, Madhur; Rampino, Antonio; Sportelli, Leonardo; Trevisan, Nicolò; Drago, Filippo; Papaleo, Francesco; Sambataro, Fabio; Pergola, Giulio; Marco Leggio, Gian | |
| Tensor-Based Decomposition Associates Striatal Gene Co-Expression With Increased Dopamine Signaling in Individuals at Genetic Risk for Schizophrenia | 1-gen-2022 | Sportelli, Leonardo; Eisenberg, Daniel; D'Ambrosio, Enrico; Passiatore, Roberta; Bertolino, Alessandro; Chen, Qiang; Czarapata, Jasmine; Gregory, Michael; Griffiths, Kira; Hyde, Thomas; Kleinman, Joel; Pardinas, Antonio F.; Shin, Joo Heon; Veronese, Mattia; Zink, Caroline; Howes, Oliver; Berman, Karen; Weinberger, Daniel; Pergola, Giulio | |
| The interaction between early life complications and a polygenic risk score for schizophrenia is associated with brain activity during emotion processing in healthy participants | 1-gen-2024 | Toro, Veronica Debora; Antonucci, Linda A.; Quarto, Tiziana; Passiatore, Roberta; Fazio, Leonardo; Ursini, Gianluca; Chen, Qiang; Masellis, Rita; Torretta, Silvia; Sportelli, Leonardo; Kikidis, Gianluca Christos; Massari, Francesco; D'Ambrosio, Enrico; Rampino, Antonio; Pergola, Giulio; Weinberger, Daniel R.; Bertolino, Alessandro; Blasi, Giuseppe |