Schizophrenia is thought to be a neurodevelopmental brain disorder with genetic risk being associated with shifting clinical phenomena across the lifespan. We investigated the convergence of schizophrenia risk genes in brain co-expression networks in postmortem human prefrontal cortex (DLPFC), hippocampus, caudate nucleus and in dentate gyrus granule cells, parsed by specific age periods.
Schizophrenia Risk Genes Converge into Shifting Co-Expression Networks Across Brain Development, Ageing and Brain Regions
Pergola, Giulio;Sportelli, Leonardo;Blasi, Giuseppe;Monaco, Alfonso;Bertolino, Alessandro;
2022-01-01
Abstract
Schizophrenia is thought to be a neurodevelopmental brain disorder with genetic risk being associated with shifting clinical phenomena across the lifespan. We investigated the convergence of schizophrenia risk genes in brain co-expression networks in postmortem human prefrontal cortex (DLPFC), hippocampus, caudate nucleus and in dentate gyrus granule cells, parsed by specific age periods.File in questo prodotto:
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