IRIS
CATTO, Marco
 Distribuzione geografica
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Continente #
NA - Nord America 12.341
AS - Asia 4.785
EU - Europa 4.699
SA - Sud America 1.188
Continente sconosciuto - Info sul continente non disponibili 655
AF - Africa 203
OC - Oceania 7
AN - Antartide 2
Totale 23.880
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Nazione #
US - Stati Uniti d'America 11.930
SG - Singapore 1.819
IT - Italia 1.507
CN - Cina 1.219
BR - Brasile 953
DE - Germania 602
SE - Svezia 598
HK - Hong Kong 559
RU - Federazione Russa 554
VN - Vietnam 360
FR - Francia 294
GB - Regno Unito 276
FI - Finlandia 217
UA - Ucraina 192
IN - India 186
CA - Canada 185
LT - Lituania 178
BD - Bangladesh 102
ID - Indonesia 83
AR - Argentina 82
MX - Messico 68
TR - Turchia 55
JP - Giappone 49
PL - Polonia 47
IQ - Iraq 46
NL - Olanda 46
ZA - Sudafrica 43
BE - Belgio 39
CI - Costa d'Avorio 39
EC - Ecuador 38
PH - Filippine 38
CO - Colombia 35
MA - Marocco 35
IE - Irlanda 34
PK - Pakistan 33
IR - Iran 31
CR - Costa Rica 28
IL - Israele 28
AT - Austria 27
ES - Italia 27
VE - Venezuela 26
SA - Arabia Saudita 25
GT - Guatemala 20
EG - Egitto 18
JM - Giamaica 18
CW - ???statistics.table.value.countryCode.CW??? 16
CZ - Repubblica Ceca 16
MY - Malesia 16
NI - Nicaragua 16
TN - Tunisia 16
UZ - Uzbekistan 16
AE - Emirati Arabi Uniti 15
CL - Cile 15
PY - Paraguay 15
TT - Trinidad e Tobago 15
SV - El Salvador 14
HN - Honduras 13
KE - Kenya 13
PE - Perù 12
CH - Svizzera 11
NP - Nepal 10
OM - Oman 10
TH - Thailandia 10
AZ - Azerbaigian 9
DZ - Algeria 9
KR - Corea 9
GP - Guadalupe 8
JO - Giordania 8
KG - Kirghizistan 8
PR - Porto Rico 8
SC - Seychelles 8
ET - Etiopia 7
BO - Bolivia 6
RO - Romania 6
SY - Repubblica araba siriana 6
TW - Taiwan 6
KZ - Kazakistan 5
LB - Libano 5
AU - Australia 4
BY - Bielorussia 4
EU - Europa 4
NG - Nigeria 4
SK - Slovacchia (Repubblica Slovacca) 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
DO - Repubblica Dominicana 3
EE - Estonia 3
PA - Panama 3
RS - Serbia 3
UY - Uruguay 3
BB - Barbados 2
BH - Bahrain 2
BS - Bahamas 2
DK - Danimarca 2
GE - Georgia 2
KW - Kuwait 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
QA - Qatar 2
Totale 23.208
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Città #
Ashburn 1.447
Singapore 976
Fairfield 921
San Jose 909
Chandler 762
Hong Kong 544
Woodbridge 544
Milan 510
Nyköping 460
Jacksonville 413
Houston 404
Beijing 380
Seattle 374
Ann Arbor 347
Dallas 345
Cambridge 330
Wilmington 320
Council Bluffs 316
Bari 184
Vilnius 162
Lauterbourg 161
Boardman 158
New York 152
Roxbury 149
Los Angeles 148
Lawrence 145
Nanjing 132
Rome 128
Ho Chi Minh City 122
Santa Clara 118
Helsinki 108
São Paulo 107
Washington 99
Des Moines 93
Dearborn 92
Brooklyn 86
Munich 78
Princeton 72
Hanoi 69
North Bergen 67
Buffalo 63
Columbus 63
Falkenstein 63
Jakarta 59
Atlanta 53
Chicago 51
Figino 51
San Diego 50
Montreal 48
Moscow 45
Inglewood 44
Nanchang 43
Frankfurt am Main 41
Hebei 41
Tokyo 41
London 40
Abidjan 39
Brussels 39
Marseille 36
Phoenix 36
Shenyang 36
Jiaxing 35
Dublin 33
Naples 32
Turin 32
Warsaw 31
Orem 30
Guangzhou 29
Johannesburg 29
Nuremberg 29
Paris 29
Belo Horizonte 28
Rio de Janeiro 28
Denver 27
Kansas City 27
San Francisco 27
Chennai 26
Toronto 26
Mexico City 22
Baghdad 21
Poplar 21
Redwood City 21
San José 21
Shanghai 21
Tianjin 21
Florence 20
New Delhi 20
Boston 19
The Dalles 19
Amsterdam 18
Brasília 18
Guatemala City 17
Haiphong 17
Augusta 16
Bologna 16
Porto Alegre 16
Quito 16
Stockholm 16
Willemstad 16
Managua 15
Totale 14.819
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Nome #
A rational approach to elucidate human monoamine oxidase molecular selectivity 382
Applicability Domain for QSAR models: where theory meets reality 277
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 249
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 229
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease 229
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 222
Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones 220
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 217
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease 214
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 213
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 213
Discovery of Potent Dual Binding Site Acetylcholinesterase Inhibitors via Homo- and Heterodimerization of Coumarin-Based Moieties 212
Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors 208
Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity 206
Repositioning of dantrolene for Alzheimer’s disease: new and old biological activities towards AD-related targets. 206
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 203
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. 202
Mind the Gap ! A Journey towards Computational Toxicology 201
Alloxan Derivatives as Inhibitors of Matrix Metalloproteinase-2: Theoretical Calculations and Experimental Results 199
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl) hydrazone: a water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity 192
Multitarget Drug Design for Neurodegenerative Diseases 190
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 190
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 190
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 188
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 186
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 186
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 183
Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitors 183
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. 180
A Multi-Objective Optimization Algorithm for Molecular Design 180
Structure-property relationship study of the HPLC enantio-selective retention of neuroprotective 7-[(1-alkylpiperidin-3-yl)methoxy]coumarin derivatives on an amylose-based chiral stationary phase 179
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 177
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation 173
Novel chemotypes targeting tubulin at the Colchicine binding site and unbiasing P-glycoprotein 172
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 172
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 170
Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on β-amyloid(1-40) aggregation and toxicity 168
A multitarget approach in cancer research 163
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 161
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 157
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 156
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 156
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS 155
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 155
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 155
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors 151
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 151
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 151
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 151
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 149
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 148
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 147
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 144
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 143
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 139
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry 139
Estimation of the Binding Free Energy by Linear Interaction Energy Models 137
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 137
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 136
Synthesis and biological evaluation of arylhydrazone derivatives of indoles and indolin-2-ones as b-amyloid aggregation inhibitors 135
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones 133
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 133
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease 133
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 132
Advances in synthesis of novel annulated azecines and their unique pharmacological properties 132
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 130
Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties 130
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 129
Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease 129
Understanding of the MAO-A and B Reversible Inhibitory Activity and Selectivity by Using 3D Descriptors of Lipophilicity 127
Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies 127
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors 126
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 126
Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents 126
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics 125
Tandem cleavage of hydrogenated beta- and gamma-carbolines. New practical synthesis of tetrahydroazocino[4,5-b]indoles and tetrahydroazocino[5,4-b]indoles showing acetylcholinesterase inhibitory activity 124
Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterases 123
Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates 123
Solid Phase and Microwave Assisted Synthesis of Focused Libraries of Imatinib Analogues 122
Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activity, QSARs, and 3-D QSARs 121
Design, Synthesis and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium-like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors 121
Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as beta-amyloid aggregation inhibitors 121
Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening 120
Isatin 3-arylhydrazones: from inhibitors of amyloidogenesis to multitarget agents with potential in Alzheimer’s disease. 120
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells 119
Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: effects of lipophilicity and structure-activity relationships 119
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules 118
Impact of species-dependent differences on screening, design, and development of MAO B inhibitors 118
A second life for MAO inhibitors? From CNS diseases to anticancer therapy 116
Biophysical characterization of inhibition of Aβ fibril formation by isatin-3-arylhydrazones 116
Derivatives of annulated tetrahydroazocines and tetrahydroazonines as cholinesterase inhibitors 115
Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors 114
Screening of new ligands selective for telomeric and oncogenic G-quadruplex sequences 114
Inhibition of Monoamine Oxidases by Functionalized Coumarin Derivatives: Biological Activities, Quantitative Structure-Activity Relationships (QSARs) and 3D-QSAR 114
Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity 113
Synthesis and biological evaluation of arylhydrazone derivatives of indoles and indolin-2-ones as β-amyloid aggregation inhibitors 112
Natural scaffolds with potential metal chelating activity for the multi-target therapy of Alzheimer's Disease: a preliminary study 112
Novel Phenothiazine/Donepezil-Like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease 111
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases 111
Synthesis and Biological Evaluation of Dantrolene-Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases 109
Totale 15.841
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Categoria #
all - tutte 92.547
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.547
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022883 0 0 0 0 48 50 61 48 68 142 177 289
2022/20232.136 302 237 146 173 301 226 19 240 338 52 62 40
2023/2024875 58 122 44 129 59 161 39 25 35 33 18 152
2024/20253.353 131 90 237 144 129 256 378 295 171 142 486 894
2025/20268.001 979 394 652 838 865 432 899 279 795 663 325 880
2026/20272.736 236 358 696 1.242 204 0 0 0 0 0 0 0
Totale 23.880