IRIS
CATTO, Marco
 Distribuzione geografica
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Continente #
NA - Nord America 8.641
AS - Asia 3.877
EU - Europa 3.083
SA - Sud America 914
AF - Africa 127
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 4
AN - Antartide 2
Totale 16.653
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Nazione #
US - Stati Uniti d'America 8.498
SG - Singapore 1.580
CN - Cina 1.067
BR - Brasile 797
SE - Svezia 595
DE - Germania 549
RU - Federazione Russa 526
HK - Hong Kong 516
IT - Italia 488
VN - Vietnam 295
GB - Regno Unito 234
UA - Ucraina 183
FI - Finlandia 155
IN - India 111
FR - Francia 110
CA - Canada 67
ID - Indonesia 65
AR - Argentina 49
MX - Messico 48
BD - Bangladesh 42
PL - Polonia 41
CI - Costa d'Avorio 39
BE - Belgio 37
NL - Olanda 35
IE - Irlanda 30
IR - Iran 28
ZA - Sudafrica 28
AT - Austria 27
IQ - Iraq 26
TR - Turchia 26
JP - Giappone 25
ES - Italia 23
EC - Ecuador 20
MA - Marocco 15
CZ - Repubblica Ceca 14
LT - Lituania 14
CO - Colombia 13
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
EG - Egitto 10
PE - Perù 10
PK - Pakistan 10
TN - Tunisia 9
KR - Corea 8
SA - Arabia Saudita 8
UZ - Uzbekistan 8
CR - Costa Rica 7
JM - Giamaica 7
KE - Kenya 7
PH - Filippine 7
PY - Paraguay 7
CH - Svizzera 5
CL - Cile 5
DZ - Algeria 5
NP - Nepal 5
OM - Oman 5
EU - Europa 4
JO - Giordania 4
NG - Nigeria 4
AO - Angola 3
BY - Bielorussia 3
ET - Etiopia 3
IL - Israele 3
KG - Kirghizistan 3
LB - Libano 3
MY - Malesia 3
RO - Romania 3
SY - Repubblica araba siriana 3
AU - Australia 2
AZ - Azerbaigian 2
BB - Barbados 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GT - Guatemala 2
KZ - Kazakistan 2
NZ - Nuova Zelanda 2
PA - Panama 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TW - Taiwan 2
AL - Albania 1
AM - Armenia 1
AQ - Antartide 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
CV - Capo Verde 1
CY - Cipro 1
DK - Danimarca 1
GD - Grenada 1
GI - Gibilterra 1
GS - Georgia del Sud e Isole Sandwich Australi 1
HN - Honduras 1
IS - Islanda 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
MK - Macedonia 1
MW - Malawi 1
NI - Nicaragua 1
NO - Norvegia 1
Totale 16.643
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Città #
Fairfield 921
Ashburn 886
Singapore 804
Chandler 761
Woodbridge 544
Hong Kong 510
Nyköping 460
Jacksonville 412
Houston 400
Seattle 369
Beijing 353
Ann Arbor 347
Cambridge 329
Dallas 319
Wilmington 319
Bari 178
Roxbury 149
Lawrence 145
Nanjing 132
Los Angeles 117
New York 115
Boardman 110
Ho Chi Minh City 103
Dearborn 92
Des Moines 92
Brooklyn 79
Munich 78
Princeton 71
São Paulo 67
Hanoi 57
Jakarta 57
Milan 57
North Bergen 52
Santa Clara 52
Buffalo 48
San Diego 47
Helsinki 46
Inglewood 44
Moscow 44
Nanchang 42
Hebei 41
Abidjan 39
Brussels 37
Chicago 37
Falkenstein 37
Council Bluffs 36
Shenyang 36
Jiaxing 34
London 34
Marseille 34
Atlanta 29
Dublin 29
Guangzhou 28
Nuremberg 28
Montreal 26
Warsaw 26
Belo Horizonte 24
Chennai 24
Frankfurt am Main 24
Rio de Janeiro 24
Kansas City 23
Johannesburg 22
Paris 21
Redwood City 21
Tianjin 21
Tokyo 21
Denver 20
San Francisco 20
Poplar 19
Mexico City 17
Shanghai 17
Orem 16
Stockholm 16
Toronto 16
Brasília 15
Augusta 14
Bitonto 14
Boston 14
Dong Ket 14
Haiphong 14
Leawood 14
San Jose 14
Washington 14
Changsha 13
Ningbo 13
Porto Alegre 13
Amsterdam 12
Boydton 12
Campinas 12
Da Nang 12
Jinan 12
New Delhi 12
Phoenix 12
Rome 12
Wuhan 12
Wuxi 12
Columbus 11
Ninh Bình 11
Norwalk 11
The Dalles 11
Totale 11.035
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Nome #
Applicability Domain for QSAR models: where theory meets reality 218
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 204
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 197
A rational approach to elucidate human monoamine oxidase molecular selectivity 187
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 185
Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones 181
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease 181
Mind the Gap ! A Journey towards Computational Toxicology 176
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 171
Alloxan Derivatives as Inhibitors of Matrix Metalloproteinase-2: Theoretical Calculations and Experimental Results 170
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 170
Multitarget Drug Design for Neurodegenerative Diseases 169
Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors 168
Discovery of Potent Dual Binding Site Acetylcholinesterase Inhibitors via Homo- and Heterodimerization of Coumarin-Based Moieties 166
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 166
Repositioning of dantrolene for Alzheimer’s disease: new and old biological activities towards AD-related targets. 166
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease 165
Insights into Structure-Activity Relationships of 3-Arylhydrazonoindolin-2-One Derivatives for Their Multitarget Activity on β-Amyloid Aggregation and Neurotoxicity 164
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl) hydrazone: a water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity 156
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 155
Novel chemotypes targeting tubulin at the Colchicine binding site and unbiasing P-glycoprotein 147
Structure-property relationship study of the HPLC enantio-selective retention of neuroprotective 7-[(1-alkylpiperidin-3-yl)methoxy]coumarin derivatives on an amylose-based chiral stationary phase 147
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 146
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 146
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. 144
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 144
Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 144
Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on β-amyloid(1-40) aggregation and toxicity 143
Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitors 142
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 138
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 136
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 135
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 133
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 130
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. 130
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 129
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 128
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 125
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 122
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors 122
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 122
A multitarget approach in cancer research 121
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 121
A Multi-Objective Optimization Algorithm for Molecular Design 121
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 121
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 120
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 120
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 119
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 118
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 116
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 115
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 113
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation 112
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS 111
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 111
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 110
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 108
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones 108
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 108
Synthesis and biological evaluation of arylhydrazone derivatives of indoles and indolin-2-ones as b-amyloid aggregation inhibitors 107
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 107
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 107
Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties 105
Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening 103
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells 103
Estimation of the Binding Free Energy by Linear Interaction Energy Models 103
Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents 103
Understanding of the MAO-A and B Reversible Inhibitory Activity and Selectivity by Using 3D Descriptors of Lipophilicity 102
Solid Phase and Microwave Assisted Synthesis of Focused Libraries of Imatinib Analogues 101
Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activity, QSARs, and 3-D QSARs 100
Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterases 98
Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as beta-amyloid aggregation inhibitors 97
Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease 97
Impact of species-dependent differences on screening, design, and development of MAO B inhibitors 96
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease 96
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 96
Design, Synthesis and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium-like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors 95
Isatin 3-arylhydrazones: from inhibitors of amyloidogenesis to multitarget agents with potential in Alzheimer’s disease. 94
Tandem cleavage of hydrogenated beta- and gamma-carbolines. New practical synthesis of tetrahydroazocino[4,5-b]indoles and tetrahydroazocino[5,4-b]indoles showing acetylcholinesterase inhibitory activity 93
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry 93
Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: effects of lipophilicity and structure-activity relationships 93
Inhibition of Monoamine Oxidases by Functionalized Coumarin Derivatives: Biological Activities, Quantitative Structure-Activity Relationships (QSARs) and 3D-QSAR 91
Biophysical characterization of inhibition of Aβ fibril formation by isatin-3-arylhydrazones 91
Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies 90
Derivatives of annulated tetrahydroazocines and tetrahydroazonines as cholinesterase inhibitors 88
Alloxan derivatives as inhibitors of matrix metalloproteinases-2: theoretical calculations and experimental results 87
New Strategies in the Chemotherapy of Leukemia: Eradicating Cancer Stem Cells in Chronic Myeloid Leukemia 86
Thermodynamic Parameters, X-ray Structure, and QSAR Studies of Condensed Diazines as MAO Inhibitors 84
Discovery of a potent and selective hetero-bivalent AChE inhibitor via bioisosteric replacement 84
Screening of new ligands selective for telomeric and oncogenic G-quadruplex sequences 83
Anthracenedione and azaanthracenedione derivatives as agents able to inhibit aggregation of beta-amyloid peptides 83
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase 83
Lipophilicity Plays a Major Role in Modulating the Inhibition of Monoamine Oxidase B by 7-Substituted Coumarins 82
Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity 82
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors 82
Synthesis and Biological Evaluation of Dantrolene-Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases 82
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics 81
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease 81
Synthesis and Inhibitory Activity Towards β-Amyloid Fibril Formation of Indane and Indole Derivatives 80
Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors 79
Totale 12.229
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Categoria #
all - tutte 72.359
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.359
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021882 0 0 0 0 0 81 151 89 127 208 155 71
2021/20221.191 53 194 35 26 48 50 61 48 68 142 177 289
2022/20232.136 302 237 146 173 301 226 19 240 338 52 62 40
2023/2024875 58 122 44 129 59 161 39 25 35 33 18 152
2024/20253.353 131 90 237 144 129 256 378 295 171 142 486 894
2025/20264.100 979 394 652 839 879 357 0 0 0 0 0 0
Totale 17.243