IRIS
CAROTTI, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 11.693
EU - Europa 3.560
AS - Asia 1.682
AF - Africa 14
SA - Sud America 7
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 4
Totale 16.964
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Nazione #
US - Stati Uniti d'America 11.678
DE - Germania 1.291
CN - Cina 1.104
SE - Svezia 695
UA - Ucraina 412
SG - Singapore 362
GB - Regno Unito 288
IT - Italia 263
FI - Finlandia 259
RU - Federazione Russa 138
FR - Francia 74
VN - Vietnam 64
IE - Irlanda 54
IN - India 40
BE - Belgio 33
IR - Iran 26
JP - Giappone 22
TW - Taiwan 21
NL - Olanda 14
CA - Canada 12
CZ - Repubblica Ceca 9
TR - Turchia 9
KR - Corea 7
DK - Danimarca 6
MA - Marocco 6
NG - Nigeria 6
CH - Svizzera 5
HU - Ungheria 5
EU - Europa 4
GE - Georgia 4
RO - Romania 4
TH - Thailandia 4
BR - Brasile 3
ES - Italia 3
HK - Hong Kong 3
NZ - Nuova Zelanda 3
AM - Armenia 2
DZ - Algeria 2
EC - Ecuador 2
ID - Indonesia 2
IQ - Iraq 2
JO - Giordania 2
KW - Kuwait 2
MX - Messico 2
MY - Malesia 2
PK - Pakistan 2
PL - Polonia 2
AD - Andorra 1
AN - Antille olandesi 1
AR - Argentina 1
AT - Austria 1
AU - Australia 1
BY - Bielorussia 1
CO - Colombia 1
IM - Isola di Man 1
KZ - Kazakistan 1
LU - Lussemburgo 1
PH - Filippine 1
Totale 16.964
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Città #
Fairfield 1.753
Woodbridge 1.151
Chandler 1.050
Jacksonville 954
Houston 780
Ashburn 734
Seattle 676
Wilmington 605
Cambridge 585
Nyköping 486
Ann Arbor 453
Singapore 287
Nanjing 275
Roxbury 245
Lawrence 240
Boardman 163
Des Moines 158
Beijing 156
Princeton 150
Bari 113
Dearborn 99
New York 95
Brooklyn 80
Shenyang 78
Hebei 73
Nanchang 73
San Diego 70
Inglewood 65
Dong Ket 59
Jiaxing 59
Dublin 54
Tianjin 41
Santa Clara 38
Marseille 35
Guangzhou 32
Los Angeles 31
Brussels 30
Jinan 29
Redwood City 29
Munich 27
Changsha 26
Kansas City 23
Zhengzhou 23
Milan 21
Shanghai 21
Helsinki 20
London 19
Ningbo 19
San Mateo 19
Augusta 17
Paris 17
Leawood 16
Taipei 16
Ardabil 14
Monmouth Junction 13
Norwalk 13
Pune 13
Washington 13
Auburn Hills 12
Hefei 11
Rome 11
Kunming 10
Hangzhou 9
Wuhan 9
Bitonto 8
Romola 8
West Jordan 8
Amsterdam 7
Brno 7
Islington 7
Taizhou 7
Wako 7
Boydton 6
Prescot 6
Toronto 6
Grafing 5
Gravina In Puglia 5
Hanoi 5
Jinhua 5
Lagos 5
Lyngby 5
Mumbai 5
Sheffield 5
Wuxi 5
Yiwu 5
Hounslow 4
Istanbul 4
Kilburn 4
Nantou City 4
Salice Salentino 4
San Francisco 4
St Albans 4
Acton 3
Asahi 3
Budapest 3
Chengdu 3
Falls Church 3
Indiana 3
Jaipur 3
Lanzhou 3
Totale 12.675
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Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 218
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 217
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 150
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 143
Applicability Domain for QSAR models: where theory meets reality 138
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 132
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 129
Mind the Gap ! A Journey towards Computational Toxicology 127
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 122
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 120
Integration of QSAR models for bioconcentration suitable for REACH 119
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 119
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 116
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 114
Partitioning behaviour of piracetam-type cognition enhancers 113
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 112
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 112
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 111
A convenient synthesis of nitriles from primary amides under mild conditions 110
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 110
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 110
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 104
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 103
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 103
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 102
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 102
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 101
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 101
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 101
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 100
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 99
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 99
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 98
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 98
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 97
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 97
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 96
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 96
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 95
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 95
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 94
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 94
The practice of medicinal chemistry 94
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 94
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 94
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 94
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 93
Le applicazioni della chimica farmaceutica 93
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 93
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 93
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 93
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 92
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 92
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 91
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 91
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 91
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 91
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 90
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 90
An easy, high-yield conversion of aldoximes to nitriles 89
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 89
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 89
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 88
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 88
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 88
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 88
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 88
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 87
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 87
CHEMICAL AND CATALYTIC REDUCTIVE ISOMERIZATION OF [1,3]-OXAZINO-[2,3-A]-ISOQUINOLINES TO 1,3-OXAZINO-[3,2-B]-ISOQUINOLINES 85
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 85
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 85
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 84
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 84
Tetraoxoderivatives of Perhydropyrrolo[3,4-c]pyridine 84
A Round Trip from Medicinal Chemistry to Predictive Toxicology 84
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 84
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 83
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 83
Screening of benzamidine-based thrombin inhibitors via a linear interaction energy in continuum electrostatics model 82
Enantiomeric Resolution of Sulfoxides on a DACH-DNB Chiral Stationary Phase: a Quantitative Structure-Enantioselective Retention Relationship (QSERR) Study 82
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 81
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 81
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 80
Advanced methodologies in medicinal chemistry research 80
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 80
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents. 78
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 78
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 78
Papain catalyzed hydrolysis of aryl esters: a comparison of the Hansch, Docking and CoMFA methods 77
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 77
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells 76
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 76
Studio dell’Idrolisi Chimica e Plasmatica di Aril-nipecotati ad Attività Gaba-mimetica Attraverso Analisi Regressionale 76
REACH and in silico methods: an attractive opportunity for medicinal chemists 76
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 76
High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones. 75
Neuronal Nicotinic Agonists: a Multi-approach Development of the Pharmacophore 75
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. 75
Novel, potent and selective 17b-hydroxysteroid dehydrogenase type 2-inhibitors as potential therapeutics for osteoporosis with dual human and mouse activities 74
Totale 9.741
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Categoria #
all - tutte 64.466
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.466
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.687 0 0 0 0 428 298 462 354 497 216 335 97
2020/20212.341 253 169 169 163 255 110 188 144 194 325 198 173
2021/20221.665 69 242 13 98 77 80 94 84 96 166 296 350
2022/20232.861 472 196 147 284 428 362 16 317 520 15 49 55
2023/2024910 80 172 32 142 60 151 30 31 26 27 25 134
2024/2025691 99 73 351 131 37 0 0 0 0 0 0 0
Totale 17.230