IRIS
CAROTTI, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 14.868
AS - Asia 4.807
EU - Europa 4.290
SA - Sud America 1.152
AF - Africa 115
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 4
Totale 25.243
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Nazione #
US - Stati Uniti d'America 14.727
SG - Singapore 1.944
CN - Cina 1.432
DE - Germania 1.354
BR - Brasile 1.002
SE - Svezia 708
HK - Hong Kong 616
RU - Federazione Russa 544
UA - Ucraina 421
VN - Vietnam 367
GB - Regno Unito 360
IT - Italia 294
FI - Finlandia 281
IN - India 98
FR - Francia 95
CA - Canada 71
AR - Argentina 61
IE - Irlanda 56
MX - Messico 43
JP - Giappone 41
BE - Belgio 37
ID - Indonesia 36
BD - Bangladesh 35
IQ - Iraq 35
TR - Turchia 35
EC - Ecuador 31
TW - Taiwan 31
IR - Iran 30
NL - Olanda 30
PL - Polonia 29
CI - Costa d'Avorio 28
ZA - Sudafrica 27
PK - Pakistan 20
ES - Italia 16
MA - Marocco 16
VE - Venezuela 16
CO - Colombia 14
CZ - Repubblica Ceca 11
PY - Paraguay 10
SA - Arabia Saudita 10
UZ - Uzbekistan 9
AT - Austria 8
CR - Costa Rica 8
KR - Corea 8
LT - Lituania 8
NP - Nepal 8
TN - Tunisia 8
DZ - Algeria 7
NG - Nigeria 7
PE - Perù 7
DK - Danimarca 6
EG - Egitto 6
KE - Kenya 6
KZ - Kazakistan 6
RO - Romania 6
CH - Svizzera 5
HU - Ungheria 5
OM - Oman 5
AE - Emirati Arabi Uniti 4
AZ - Azerbaigian 4
CL - Cile 4
EU - Europa 4
GE - Georgia 4
JO - Giordania 4
NZ - Nuova Zelanda 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
GT - Guatemala 3
MY - Malesia 3
PS - Palestinian Territory 3
UY - Uruguay 3
AM - Armenia 2
AO - Angola 2
AU - Australia 2
BO - Bolivia 2
BY - Bielorussia 2
HR - Croazia 2
JM - Giamaica 2
KG - Kirghizistan 2
KW - Kuwait 2
LB - Libano 2
PA - Panama 2
PH - Filippine 2
AD - Andorra 1
AN - Antille olandesi 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BS - Bahamas 1
CD - Congo 1
CG - Congo 1
GD - Grenada 1
GF - Guiana Francese 1
GI - Gibilterra 1
GY - Guiana 1
HN - Honduras 1
IL - Israele 1
Totale 25.230
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Città #
Dallas 2.075
Fairfield 1.753
Woodbridge 1.151
Chandler 1.050
Ashburn 1.013
Jacksonville 956
Singapore 951
Houston 784
Seattle 679
Hong Kong 613
Wilmington 605
Cambridge 585
Nyköping 486
Ann Arbor 453
Beijing 354
Nanjing 275
Roxbury 245
Lawrence 240
Boardman 164
Des Moines 159
Princeton 150
New York 122
Ho Chi Minh City 118
Bari 113
Brooklyn 102
Dearborn 99
Los Angeles 99
Shenyang 79
Hebei 73
Nanchang 73
San Diego 70
São Paulo 70
Hanoi 67
Inglewood 65
Dong Ket 59
Jiaxing 59
Munich 59
Dublin 56
Buffalo 52
Santa Clara 52
Tianjin 42
Helsinki 37
Moscow 37
Rio de Janeiro 37
North Bergen 36
Marseille 35
Brussels 34
Guangzhou 34
Jinan 29
Redwood City 29
Abidjan 28
Changsha 28
London 27
Chicago 26
Milan 26
San Francisco 25
Zhengzhou 25
Kansas City 24
Belo Horizonte 22
Warsaw 22
Atlanta 21
Johannesburg 21
Shanghai 21
Tokyo 21
Brasília 20
Montreal 20
Toronto 20
Augusta 19
Ningbo 19
San Mateo 19
Paris 17
Rome 17
Jakarta 16
Leawood 16
Salvador 16
Taipei 16
Denver 15
Nuremberg 15
Ardabil 14
Chennai 14
Curitiba 14
Stockholm 14
Washington 14
Monmouth Junction 13
Norwalk 13
Pune 13
Ribeirão Preto 13
Amsterdam 12
Auburn Hills 12
Campinas 12
Haiphong 12
Orem 12
Quito 12
San Jose 12
Ankara 11
Baghdad 11
Boston 11
Fortaleza 11
Guarulhos 11
Hefei 11
Totale 17.432
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Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.054
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.038
Applicability Domain for QSAR models: where theory meets reality 218
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 204
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 197
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 185
Mind the Gap ! A Journey towards Computational Toxicology 176
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 171
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 166
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 155
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 155
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 154
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 150
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 150
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 147
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 146
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 146
Partitioning behaviour of piracetam-type cognition enhancers 145
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 144
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 144
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 144
Integration of QSAR models for bioconcentration suitable for REACH 143
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 143
A convenient synthesis of nitriles from primary amides under mild conditions 142
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 142
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 141
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 141
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 140
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 138
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 138
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 136
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 135
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 134
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 134
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 134
A Round Trip from Medicinal Chemistry to Predictive Toxicology 133
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 133
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 131
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 130
Le applicazioni della chimica farmaceutica 129
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 129
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 129
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 129
The practice of medicinal chemistry 128
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 128
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 127
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 126
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 126
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 126
Advanced methodologies in medicinal chemistry research 125
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 125
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 125
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 125
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 124
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 124
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 123
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 122
Benzodiazepine receptor affinities, behavioural and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice 122
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 122
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 122
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 121
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 121
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 120
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 120
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 120
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 120
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 119
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 119
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 118
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 117
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 117
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 117
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 117
An easy, high-yield conversion of aldoximes to nitriles 116
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 116
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 115
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 113
A chemocentric approach to the identification of cancer targets 113
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 112
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 112
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 111
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 111
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 111
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 111
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. 111
Benzenesulfonamide inhibitors of carbonic anhydrase: study of their hydrophobicity by RPLC. 111
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 110
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 110
Tetraoxoderivatives of Perhydropyrrolo[3,4-c]pyridine 110
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 110
REACH and in silico methods: an attractive opportunity for medicinal chemists 109
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 108
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 108
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 108
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 108
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 107
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 107
Enantiomeric Resolution of Sulfoxides on a DACH-DNB Chiral Stationary Phase: a Quantitative Structure-Enantioselective Retention Relationship (QSERR) Study 106
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 105
QSAR of Teicoplanin Antibiotics: Influence of Lipophilicity and Ionic Properties on their in vivo Antimicrobial Activity 105
Totale 14.813
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Categoria #
all - tutte 94.511
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 94.511
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.332 0 0 0 0 0 110 188 144 194 325 198 173
2021/20221.665 69 242 13 98 77 80 94 84 96 166 296 350
2022/20232.861 472 196 147 284 428 362 16 317 520 15 49 55
2023/2024910 80 172 32 142 60 151 30 31 26 27 25 134
2024/20253.397 99 73 351 131 60 236 180 280 186 163 491 1.147
2025/20265.576 1.026 683 2.016 846 679 326 0 0 0 0 0 0
Totale 25.512