IRIS
CAROTTI, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 15.908
AS - Asia 5.464
EU - Europa 4.665
SA - Sud America 1.384
AF - Africa 177
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 4
Totale 27.610
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Nazione #
US - Stati Uniti d'America 15.739
SG - Singapore 2.124
CN - Cina 1.529
DE - Germania 1.386
BR - Brasile 1.118
SE - Svezia 709
HK - Hong Kong 633
RU - Federazione Russa 553
UA - Ucraina 427
VN - Vietnam 399
GB - Regno Unito 368
FI - Finlandia 330
FR - Francia 316
IT - Italia 316
IN - India 169
AR - Argentina 99
CA - Canada 82
BD - Bangladesh 81
IQ - Iraq 67
TR - Turchia 60
IE - Irlanda 57
JP - Giappone 54
ID - Indonesia 53
MX - Messico 49
ZA - Sudafrica 47
EC - Ecuador 45
PK - Pakistan 41
BE - Belgio 37
VE - Venezuela 35
NL - Olanda 34
CO - Colombia 33
PL - Polonia 32
TW - Taiwan 31
IR - Iran 30
CI - Costa d'Avorio 29
MA - Marocco 27
PH - Filippine 25
SA - Arabia Saudita 25
ES - Italia 22
UZ - Uzbekistan 22
PY - Paraguay 19
EG - Egitto 15
MY - Malesia 15
TN - Tunisia 14
CZ - Repubblica Ceca 12
CR - Costa Rica 11
NP - Nepal 11
AT - Austria 10
AZ - Azerbaigian 10
BO - Bolivia 10
CL - Cile 10
KE - Kenya 10
KR - Corea 9
PE - Perù 9
DK - Danimarca 8
DZ - Algeria 8
JO - Giordania 8
LT - Lituania 8
NG - Nigeria 8
OM - Oman 8
AE - Emirati Arabi Uniti 7
HU - Ungheria 7
KZ - Kazakistan 7
PS - Palestinian Territory 7
RO - Romania 7
TH - Thailandia 7
CH - Svizzera 6
ET - Etiopia 6
DO - Repubblica Dominicana 5
KG - Kirghizistan 5
EU - Europa 4
GE - Georgia 4
IL - Israele 4
LB - Libano 4
NI - Nicaragua 4
NZ - Nuova Zelanda 4
PA - Panama 4
SY - Repubblica araba siriana 4
TT - Trinidad e Tobago 4
AO - Angola 3
AU - Australia 3
EE - Estonia 3
GT - Guatemala 3
HR - Croazia 3
KW - Kuwait 3
UY - Uruguay 3
AM - Armenia 2
BY - Bielorussia 2
JM - Giamaica 2
MN - Mongolia 2
RS - Serbia 2
SN - Senegal 2
AD - Andorra 1
AN - Antille olandesi 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BS - Bahamas 1
CD - Congo 1
Totale 27.587
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Città #
Dallas 2.076
Fairfield 1.753
Woodbridge 1.151
Ashburn 1.131
Singapore 1.076
Chandler 1.050
Jacksonville 956
Houston 784
Seattle 681
Hong Kong 628
San Jose 619
Wilmington 605
Cambridge 585
Nyköping 486
Ann Arbor 453
Beijing 360
Nanjing 275
Roxbury 245
Lawrence 240
Lauterbourg 211
Boardman 164
Des Moines 160
Princeton 150
Ho Chi Minh City 127
New York 127
Bari 113
Brooklyn 104
Los Angeles 103
Dearborn 99
Helsinki 86
São Paulo 84
Shenyang 79
Hanoi 77
Hebei 73
Nanchang 73
San Diego 71
Inglewood 65
Jiaxing 61
Dong Ket 59
Munich 59
Dublin 57
Santa Clara 56
Buffalo 54
Tianjin 42
Rio de Janeiro 41
Moscow 38
Council Bluffs 37
North Bergen 36
Guangzhou 35
Marseille 35
Brussels 34
Tokyo 32
Abidjan 29
Chicago 29
Jinan 29
Redwood City 29
Changsha 28
Baghdad 27
Johannesburg 27
London 27
San Francisco 27
Atlanta 26
Milan 26
Belo Horizonte 25
Shanghai 25
Warsaw 25
Zhengzhou 25
Frankfurt am Main 24
Kansas City 24
Orem 24
Jakarta 23
Toronto 23
Brasília 21
Falkenstein 21
Montreal 21
Rome 21
Tashkent 21
Augusta 19
Denver 19
Ningbo 19
San Mateo 19
Salvador 18
Chennai 17
Paris 17
Campinas 16
Caracas 16
Lahore 16
Leawood 16
Nuremberg 16
Taipei 16
Curitiba 15
Istanbul 15
Pune 15
Stockholm 15
Amsterdam 14
Ardabil 14
Fortaleza 14
New Delhi 14
Porto Alegre 14
Quito 14
Totale 18.791
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Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.073
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.058
Applicability Domain for QSAR models: where theory meets reality 240
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 220
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 212
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 201
Mind the Gap ! A Journey towards Computational Toxicology 190
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 187
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 182
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 178
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 177
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 169
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 167
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 163
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 163
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 162
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 161
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 161
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 161
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 161
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 157
A convenient synthesis of nitriles from primary amides under mild conditions 156
Partitioning behaviour of piracetam-type cognition enhancers 156
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 154
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 154
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 153
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 152
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 152
Integration of QSAR models for bioconcentration suitable for REACH 151
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 151
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 150
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 148
A Round Trip from Medicinal Chemistry to Predictive Toxicology 147
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 146
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 146
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 146
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 146
Le applicazioni della chimica farmaceutica 145
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 144
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 143
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 143
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 140
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 139
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 138
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 137
The practice of medicinal chemistry 137
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 137
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 137
Advanced methodologies in medicinal chemistry research 136
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 136
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 136
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 136
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 135
Benzodiazepine receptor affinities, behavioural and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice 134
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 134
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 133
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 133
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 133
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 133
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 132
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 132
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 131
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 131
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 131
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 131
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 131
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 130
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 130
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 128
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 127
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 126
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 126
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 125
An easy, high-yield conversion of aldoximes to nitriles 125
A chemocentric approach to the identification of cancer targets 124
Benzenesulfonamide inhibitors of carbonic anhydrase: study of their hydrophobicity by RPLC. 124
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 123
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 123
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 123
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 122
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 121
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 121
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 121
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 120
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 120
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 119
QSAR of Teicoplanin Antibiotics: Influence of Lipophilicity and Ionic Properties on their in vivo Antimicrobial Activity 119
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 119
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 118
Enantiomeric Resolution of Sulfoxides on a DACH-DNB Chiral Stationary Phase: a Quantitative Structure-Enantioselective Retention Relationship (QSERR) Study 118
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 117
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 117
REACH and in silico methods: an attractive opportunity for medicinal chemists 117
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 116
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 116
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 116
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. 116
CHEMICAL AND CATALYTIC REDUCTIVE ISOMERIZATION OF [1,3]-OXAZINO-[2,3-A]-ISOQUINOLINES TO 1,3-OXAZINO-[3,2-B]-ISOQUINOLINES 115
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 115
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 115
Totale 16.001
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Categoria #
all - tutte 98.967
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 98.967
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021696 0 0 0 0 0 0 0 0 0 325 198 173
2021/20221.665 69 242 13 98 77 80 94 84 96 166 296 350
2022/20232.861 472 196 147 284 428 362 16 317 520 15 49 55
2023/2024910 80 172 32 142 60 151 30 31 26 27 25 134
2024/20253.397 99 73 351 131 60 236 180 280 186 163 491 1.147
2025/20267.943 1.026 683 2.016 846 679 393 863 261 609 567 0 0
Totale 27.879