IRIS
CAROTTI, Angelo
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 16.203
AS - Asia 5.514
EU - Europa 4.685
SA - Sud America 1.385
AF - Africa 177
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 4
Totale 27.976
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 16.018
SG - Singapore 2.138
CN - Cina 1.543
DE - Germania 1.386
BR - Brasile 1.119
SE - Svezia 709
HK - Hong Kong 640
RU - Federazione Russa 553
UA - Ucraina 427
VN - Vietnam 399
GB - Regno Unito 368
IT - Italia 331
FI - Finlandia 330
FR - Francia 316
IN - India 179
AR - Argentina 99
CA - Canada 93
BD - Bangladesh 82
IQ - Iraq 67
TR - Turchia 60
IE - Irlanda 57
JP - Giappone 54
ID - Indonesia 53
MX - Messico 52
ZA - Sudafrica 47
EC - Ecuador 45
PK - Pakistan 41
BE - Belgio 37
NL - Olanda 36
VE - Venezuela 35
CO - Colombia 33
IR - Iran 33
PL - Polonia 32
TW - Taiwan 31
CI - Costa d'Avorio 29
MA - Marocco 27
PH - Filippine 25
SA - Arabia Saudita 25
ES - Italia 22
UZ - Uzbekistan 22
PY - Paraguay 19
EG - Egitto 15
MY - Malesia 15
TN - Tunisia 14
CZ - Repubblica Ceca 12
CR - Costa Rica 11
NP - Nepal 11
AT - Austria 10
AZ - Azerbaigian 10
BO - Bolivia 10
CL - Cile 10
KE - Kenya 10
KR - Corea 9
PE - Perù 9
CH - Svizzera 8
DK - Danimarca 8
DZ - Algeria 8
JO - Giordania 8
LT - Lituania 8
NG - Nigeria 8
OM - Oman 8
AE - Emirati Arabi Uniti 7
HU - Ungheria 7
KZ - Kazakistan 7
PS - Palestinian Territory 7
RO - Romania 7
TH - Thailandia 7
ET - Etiopia 6
DO - Repubblica Dominicana 5
KG - Kirghizistan 5
EU - Europa 4
GE - Georgia 4
IL - Israele 4
LB - Libano 4
NI - Nicaragua 4
NZ - Nuova Zelanda 4
PA - Panama 4
SY - Repubblica araba siriana 4
TT - Trinidad e Tobago 4
AO - Angola 3
AU - Australia 3
EE - Estonia 3
GT - Guatemala 3
HR - Croazia 3
JM - Giamaica 3
KW - Kuwait 3
UY - Uruguay 3
AM - Armenia 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
MN - Mongolia 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
AD - Andorra 1
AN - Antille olandesi 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
Totale 27.952
Salva come PNG Salva come JPEG
Città #
Dallas 2.082
Fairfield 1.754
Woodbridge 1.151
Ashburn 1.148
Singapore 1.083
Chandler 1.050
Jacksonville 956
Houston 787
San Jose 707
Seattle 681
Hong Kong 635
Wilmington 605
Cambridge 585
Nyköping 486
Ann Arbor 453
Beijing 364
Nanjing 275
Roxbury 245
Lawrence 240
Lauterbourg 211
Boardman 172
Des Moines 160
Princeton 150
New York 135
Ho Chi Minh City 127
Bari 113
Brooklyn 107
Los Angeles 103
Dearborn 99
Helsinki 86
São Paulo 84
Shenyang 79
Hanoi 77
Hebei 73
Nanchang 73
San Diego 72
Santa Clara 66
Inglewood 65
Jiaxing 61
Dong Ket 59
Munich 59
Dublin 57
Buffalo 54
Rio de Janeiro 42
Tianjin 42
Council Bluffs 39
Moscow 38
North Bergen 37
Guangzhou 35
Marseille 35
Brussels 34
Tokyo 32
Chicago 30
Abidjan 29
Atlanta 29
Jinan 29
Redwood City 29
Changsha 28
Baghdad 27
Johannesburg 27
London 27
Milan 27
Montreal 27
San Francisco 27
Belo Horizonte 25
Kansas City 25
Shanghai 25
Warsaw 25
Zhengzhou 25
Frankfurt am Main 24
Orem 24
Toronto 24
Jakarta 23
Brasília 21
Falkenstein 21
Rome 21
Tashkent 21
Augusta 19
Denver 19
Ningbo 19
San Mateo 19
Salvador 18
Chennai 17
Paris 17
Campinas 16
Caracas 16
Lahore 16
Leawood 16
Mexico City 16
Nuremberg 16
Taipei 16
Curitiba 15
Istanbul 15
Phoenix 15
Pune 15
Stockholm 15
Washington 15
Amsterdam 14
Ardabil 14
Fortaleza 14
Totale 18.975
Salva come PNG Salva come JPEG
Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.078
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.062
Applicability Domain for QSAR models: where theory meets reality 246
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 232
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 214
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 202
Mind the Gap ! A Journey towards Computational Toxicology 193
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 192
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 188
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 183
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 178
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 171
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 169
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 167
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 165
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 165
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 164
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 164
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 162
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 162
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 161
A convenient synthesis of nitriles from primary amides under mild conditions 157
Partitioning behaviour of piracetam-type cognition enhancers 156
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 155
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 155
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 155
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 154
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 154
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 154
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 153
Integration of QSAR models for bioconcentration suitable for REACH 153
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 151
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 149
A Round Trip from Medicinal Chemistry to Predictive Toxicology 148
Le applicazioni della chimica farmaceutica 147
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 147
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 147
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 146
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 146
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 145
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 143
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 143
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 142
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 142
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 141
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 139
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 139
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 138
The practice of medicinal chemistry 138
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 138
Advanced methodologies in medicinal chemistry research 137
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 137
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 137
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 136
Benzodiazepine receptor affinities, behavioural and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice 135
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 135
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 135
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 135
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 134
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 134
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 133
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 133
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 133
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 133
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 132
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 132
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 131
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 131
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 129
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 128
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 127
An easy, high-yield conversion of aldoximes to nitriles 127
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 127
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 126
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 126
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 125
A chemocentric approach to the identification of cancer targets 125
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 124
Benzenesulfonamide inhibitors of carbonic anhydrase: study of their hydrophobicity by RPLC. 124
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 123
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 122
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 122
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 122
QSAR of Teicoplanin Antibiotics: Influence of Lipophilicity and Ionic Properties on their in vivo Antimicrobial Activity 121
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 121
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 121
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 120
Enantiomeric Resolution of Sulfoxides on a DACH-DNB Chiral Stationary Phase: a Quantitative Structure-Enantioselective Retention Relationship (QSERR) Study 120
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 119
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 119
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. 119
Studio dell’Idrolisi Chimica e Plasmatica di Aril-nipecotati ad Attività Gaba-mimetica Attraverso Analisi Regressionale 118
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 118
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 117
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 117
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 117
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 117
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 117
REACH and in silico methods: an attractive opportunity for medicinal chemists 117
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 116
Totale 16.197
Salva come PNG Salva come JPEG
Categoria #
all - tutte 104.016
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 104.016
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021173 0 0 0 0 0 0 0 0 0 0 0 173
2021/20221.665 69 242 13 98 77 80 94 84 96 166 296 350
2022/20232.861 472 196 147 284 428 362 16 317 520 15 49 55
2023/2024910 80 172 32 142 60 151 30 31 26 27 25 134
2024/20253.397 99 73 351 131 60 236 180 280 186 163 491 1.147
2025/20268.311 1.026 683 2.016 846 679 393 863 261 609 633 235 67
Totale 28.247