IRIS
CAROTTI, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 11.499
EU - Europa 3.469
AS - Asia 1.144
AF - Africa 7
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 4
Totale 16.133
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Nazione #
US - Stati Uniti d'America 11.484
DE - Germania 1.269
CN - Cina 935
SE - Svezia 699
UA - Ucraina 412
GB - Regno Unito 285
FI - Finlandia 253
IT - Italia 217
RU - Federazione Russa 135
FR - Francia 71
VN - Vietnam 64
IE - Irlanda 54
IN - India 38
BE - Belgio 33
IR - Iran 26
JP - Giappone 22
TW - Taiwan 16
CA - Canada 12
TR - Turchia 9
KR - Corea 7
NL - Olanda 7
CH - Svizzera 5
CZ - Repubblica Ceca 5
DK - Danimarca 5
HU - Ungheria 5
EU - Europa 4
GE - Georgia 4
MA - Marocco 4
RO - Romania 4
TH - Thailandia 4
BR - Brasile 3
ES - Italia 3
HK - Hong Kong 3
NZ - Nuova Zelanda 3
AM - Armenia 2
DZ - Algeria 2
EC - Ecuador 2
ID - Indonesia 2
IQ - Iraq 2
KW - Kuwait 2
MX - Messico 2
MY - Malesia 2
PL - Polonia 2
SG - Singapore 2
AD - Andorra 1
AN - Antille olandesi 1
AR - Argentina 1
AT - Austria 1
AU - Australia 1
BY - Bielorussia 1
IM - Isola di Man 1
JO - Giordania 1
KZ - Kazakistan 1
LU - Lussemburgo 1
NG - Nigeria 1
PH - Filippine 1
PK - Pakistan 1
Totale 16.133
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Città #
Fairfield 1.753
Woodbridge 1.151
Chandler 1.054
Jacksonville 954
Houston 780
Ashburn 724
Seattle 676
Wilmington 605
Cambridge 585
Nyköping 490
Ann Arbor 453
Nanjing 275
Roxbury 245
Lawrence 241
Des Moines 158
Princeton 150
Beijing 146
Boardman 132
Bari 106
Dearborn 99
New York 95
Brooklyn 80
Shenyang 78
Hebei 73
Nanchang 72
San Diego 70
Inglewood 65
Dong Ket 59
Jiaxing 57
Dublin 54
Tianjin 41
Marseille 35
Brussels 30
Redwood City 29
Jinan 28
Changsha 26
Kansas City 23
Zhengzhou 23
Guangzhou 22
Los Angeles 20
Ningbo 19
San Mateo 19
Milan 18
Augusta 17
Leawood 16
London 16
Paris 16
Taipei 16
Helsinki 15
Ardabil 14
Monmouth Junction 13
Norwalk 13
Pune 13
Washington 13
Auburn Hills 12
Hefei 11
Kunming 10
Rome 10
Hangzhou 8
Munich 8
West Jordan 8
Islington 7
Prescot 7
Wako 7
Boydton 6
Taizhou 6
Toronto 6
Grafing 5
Gravina In Puglia 5
Hanoi 5
Lyngby 5
Mumbai 5
Sheffield 5
Hounslow 4
Istanbul 4
Kilburn 4
Salice Salentino 4
San Francisco 4
St Albans 4
Acton 3
Asahi 3
Brno 3
Budapest 3
Chengdu 3
Falls Church 3
Indiana 3
Jaipur 3
Lanzhou 3
Strasbourg 3
Tokyo 3
Xian 3
Bergamo 2
Cedar Knolls 2
Chaoyang 2
Chiswick 2
Cosenza 2
Düsseldorf 2
Fuzhou 2
Isfahan 2
Kuwait 2
Totale 12.189
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Nome #
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 194
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 191
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 145
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 136
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 124
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 123
Mind the Gap ! A Journey towards Computational Toxicology 123
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 118
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 118
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 117
Integration of QSAR models for bioconcentration suitable for REACH 115
Applicability Domain for QSAR models: where theory meets reality 115
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 112
Partitioning behaviour of piracetam-type cognition enhancers 111
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 109
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 109
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 109
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 108
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 107
A convenient synthesis of nitriles from primary amides under mild conditions 105
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 103
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 101
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 100
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 99
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 99
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 99
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 98
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 97
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 97
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 96
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 96
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 95
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 95
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 94
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 94
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 94
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 92
The practice of medicinal chemistry 92
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 92
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 91
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 91
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 91
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 91
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 91
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 91
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 90
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 89
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 89
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 89
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 89
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 88
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 88
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 88
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 88
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 88
Le applicazioni della chimica farmaceutica 87
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 87
An easy, high-yield conversion of aldoximes to nitriles 87
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 85
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 85
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 85
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 84
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 84
CHEMICAL AND CATALYTIC REDUCTIVE ISOMERIZATION OF [1,3]-OXAZINO-[2,3-A]-ISOQUINOLINES TO 1,3-OXAZINO-[3,2-B]-ISOQUINOLINES 83
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 83
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 83
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 82
Tetraoxoderivatives of Perhydropyrrolo[3,4-c]pyridine 82
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 82
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 82
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 81
null 81
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 81
Enantiomeric Resolution of Sulfoxides on a DACH-DNB Chiral Stationary Phase: a Quantitative Structure-Enantioselective Retention Relationship (QSERR) Study 81
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 80
Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs 80
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 80
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 80
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 78
Screening of benzamidine-based thrombin inhibitors via a linear interaction energy in continuum electrostatics model 78
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 78
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 78
Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]-benzothiazol-, -thiazol- or -oxazol-1-ones in rodents. 76
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 76
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 76
A Round Trip from Medicinal Chemistry to Predictive Toxicology 76
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 76
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells 75
High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones. 74
Papain catalyzed hydrolysis of aryl esters: a comparison of the Hansch, Docking and CoMFA methods 74
Advanced methodologies in medicinal chemistry research 74
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 74
Neuronal Nicotinic Agonists: a Multi-approach Development of the Pharmacophore 74
Studio dell’Idrolisi Chimica e Plasmatica di Aril-nipecotati ad Attività Gaba-mimetica Attraverso Analisi Regressionale 74
REACH and in silico methods: an attractive opportunity for medicinal chemists 74
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. 73
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. 73
Addressing cytotoxicity of 1,4-biphenyl amide derivatives: discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors 73
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 73
Novel, potent and selective 17b-hydroxysteroid dehydrogenase type 2-inhibitors as potential therapeutics for osteoporosis with dual human and mouse activities 72
Totale 9.308
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Categoria #
all - tutte 53.704
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.704
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.609 0 0 0 0 0 0 0 0 0 257 632 720
2019/20204.292 747 275 133 450 428 298 462 354 497 216 335 97
2020/20212.341 253 169 169 163 255 110 188 144 194 325 198 173
2021/20221.665 69 242 13 98 77 80 94 84 96 166 296 350
2022/20232.875 474 198 148 285 432 362 16 318 523 15 49 55
2023/2024755 80 174 32 143 61 151 30 31 26 27 0 0
Totale 16.398