IRIS
CAROTTI, Angelo
 Distribuzione geografica
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Continente #
NA - Nord America 16.985
EU - Europa 5.631
AS - Asia 5.551
SA - Sud America 1.416
Continente sconosciuto - Info sul continente non disponibili 275
AF - Africa 180
OC - Oceania 8
Totale 30.046
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Nazione #
US - Stati Uniti d'America 16.771
SG - Singapore 2.153
CN - Cina 1.548
DE - Germania 1.386
IT - Italia 1.265
BR - Brasile 1.133
SE - Svezia 709
HK - Hong Kong 641
RU - Federazione Russa 553
UA - Ucraina 428
VN - Vietnam 400
GB - Regno Unito 370
FI - Finlandia 330
FR - Francia 318
IN - India 179
CA - Canada 107
AR - Argentina 103
BD - Bangladesh 89
IQ - Iraq 67
TR - Turchia 60
IE - Irlanda 57
MX - Messico 55
ID - Indonesia 54
JP - Giappone 54
EC - Ecuador 49
ZA - Sudafrica 48
PK - Pakistan 41
VE - Venezuela 39
BE - Belgio 38
CO - Colombia 38
NL - Olanda 36
IR - Iran 33
PL - Polonia 32
TW - Taiwan 31
CI - Costa d'Avorio 29
PH - Filippine 28
MA - Marocco 27
SA - Arabia Saudita 27
ES - Italia 25
UZ - Uzbekistan 22
PY - Paraguay 19
EG - Egitto 16
MY - Malesia 16
CR - Costa Rica 14
TN - Tunisia 14
CZ - Repubblica Ceca 12
NP - Nepal 11
AT - Austria 10
AZ - Azerbaigian 10
BO - Bolivia 10
CL - Cile 10
KE - Kenya 10
KR - Corea 9
PE - Perù 9
CH - Svizzera 8
DK - Danimarca 8
DZ - Algeria 8
JO - Giordania 8
LT - Lituania 8
NG - Nigeria 8
OM - Oman 8
AE - Emirati Arabi Uniti 7
HU - Ungheria 7
KZ - Kazakistan 7
PS - Palestinian Territory 7
RO - Romania 7
TH - Thailandia 7
DO - Repubblica Dominicana 6
ET - Etiopia 6
JM - Giamaica 6
KG - Kirghizistan 5
PA - Panama 5
TT - Trinidad e Tobago 5
EU - Europa 4
GE - Georgia 4
IL - Israele 4
LB - Libano 4
NI - Nicaragua 4
NZ - Nuova Zelanda 4
RS - Serbia 4
SY - Repubblica araba siriana 4
AM - Armenia 3
AO - Angola 3
AU - Australia 3
EE - Estonia 3
GT - Guatemala 3
HR - Croazia 3
KW - Kuwait 3
UY - Uruguay 3
BN - Brunei Darussalam 2
BS - Bahamas 2
BY - Bielorussia 2
CG - Congo 2
MN - Mongolia 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
SV - El Salvador 2
AD - Andorra 1
AL - Albania 1
AN - Antille olandesi 1
Totale 29.749
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Città #
Dallas 2.100
Fairfield 1.755
Ashburn 1.177
Woodbridge 1.151
Singapore 1.089
Chandler 1.050
Jacksonville 957
San Jose 831
Houston 788
Seattle 682
Hong Kong 636
Wilmington 608
Cambridge 585
Milan 577
Nyköping 486
Ann Arbor 453
Beijing 367
Council Bluffs 294
Nanjing 275
Roxbury 245
Lawrence 241
Lauterbourg 211
Boardman 172
Rome 168
Des Moines 160
Princeton 150
New York 148
Ho Chi Minh City 127
Bari 115
Los Angeles 112
Brooklyn 108
Dearborn 99
Helsinki 86
São Paulo 84
Santa Clara 83
Shenyang 79
Hanoi 77
Hebei 73
Nanchang 73
San Diego 73
Inglewood 66
Jiaxing 61
Dong Ket 59
Munich 59
Dublin 57
Buffalo 55
Figino 52
Columbus 48
Chicago 44
Rio de Janeiro 44
Tianjin 42
Moscow 38
North Bergen 38
Guangzhou 35
Marseille 35
Atlanta 34
Brussels 34
San Francisco 32
Tokyo 32
Turin 30
Abidjan 29
Jinan 29
London 29
Redwood City 29
Changsha 28
Kansas City 28
Montreal 28
Baghdad 27
Johannesburg 27
Toronto 27
Shanghai 26
Belo Horizonte 25
Phoenix 25
Warsaw 25
Zhengzhou 25
Frankfurt am Main 24
Orem 24
Jakarta 23
Brasília 22
Denver 21
Falkenstein 21
Tashkent 21
Augusta 19
Ningbo 19
San Mateo 19
Salvador 18
Caracas 17
Chennai 17
Mexico City 17
Paris 17
Campinas 16
Curitiba 16
Lahore 16
Leawood 16
Nuremberg 16
Taipei 16
Bogotá 15
Fortaleza 15
Istanbul 15
Pune 15
Totale 20.302
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Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.090
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.074
Applicability Domain for QSAR models: where theory meets reality 256
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors 241
Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data 217
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 214
Exploring Basic Tail Modifications of Coumarin-based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-soluble, Brain-permeant Neuroprotective Multitarget Agents 208
Mind the Gap ! A Journey towards Computational Toxicology 196
Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases 195
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 193
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 182
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties 180
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: Proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity 180
Inhibition of α-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 178
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 178
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 173
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 173
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat 172
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 172
A simple and Mild Procedure for the Preparation of Bile Acid Methyl Esters 169
A convenient synthesis of nitriles from primary amides under mild conditions 169
Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino4,3-bindole-4-carboxylic acids 169
Linear Solvation Energy Relationships in Reversed-Phase Liquid Chromatography. Examination of Deltabond C8 as Stationary Phase for Measuring Lipophilicity Parameters 167
X-Ray Crystal Structure, Partitioning Behavior and Molecular Modeling Study of Piracetam-type Nootropics: Insights into the Pharmacophore 167
LFER and CoMFA studies on optical resolution of a-alkyl-a-aryloxyacetic acid methyl esters on DACH-DNB chiral stationary phase 164
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 164
Partitioning behaviour of piracetam-type cognition enhancers 163
Searching for Multitargeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE−MAO B Inhibitors through the Decoration of 2H-Chromen-2-one Structural Motif 162
Integration of QSAR models for bioconcentration suitable for REACH 161
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 161
Reduction of Aldol Adducts from 1,2,3-Indantrione and Cyclic CH-acid Compounds; Keto-enol Tautomeric Study of Reduction Products 160
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 159
2-(2-Phenylcyclopropyl)-Imidazolines: Reversed Enantioselective Interaction At I1 and I2 Imidazoline Receptors 159
Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2 157
D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness. 156
A Round Trip from Medicinal Chemistry to Predictive Toxicology 156
Le applicazioni della chimica farmaceutica 155
Heterocyclic Steroids II. Synthesis of Some Spiro-Derivatives of 7,8-Diaza-11-Oxasteroids 154
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 151
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 150
Computer Aided Structure Based Design of Multitarget Leads for Alzheimer’s Disease 150
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 150
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 149
Synthesis.and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors 149
Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs 149
An integrated approach to ligand- and structure-based drug design: development and application to a series of serine protease inhibitors 148
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents 148
The practice of medicinal chemistry 146
Advanced methodologies in medicinal chemistry research 146
Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration 145
Determination of Lipophilicity and Hydrogen-bond Donor Acidity of Bioactive Sulphonyl-containing Compounds by Reversed-phase HPLC and Centrifugal Partition Chromatography and their Application to Structure-activity Relations 145
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 145
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 145
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 144
Benzodiazepine receptor affinities, behavioural and anticonvulsant activity of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones in mice 144
QSAR Analysis of the Subtilisin Hydrolysis of X-Phenyl-Hippurates II. A Study of Subtilisin BPN' 143
Lipophilicity Measurements of Benzenesulfonamide Inhibitors of Carbonic Anhydrase by Reversed-phase HPLC 143
Carbamate Prodrug Concept for Hydroxamate HDAC Inhibitors 142
On the Catalytic Reduction of Some 12-spiro-derivatives of 8-aza-11-oxasteroids 141
Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D Quantitative Structure-Activity Relationship (QSAR) models 140
9,10-Anthraquinone hinders beta-aggregation: how does a small molecule interfere with Abeta-peptide amyloid fibrillation? 140
Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase 140
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting both the Human Enzyme and its Murine Ortholog 140
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 140
In Silico Design of Novel 2H-Chromen-2-one Derivatives as Potent and Selective MAO-B Inhibitors 139
Building up QSAR model for toxicity of Psychotropic Drugs by the Monte Carlo method 136
Pyrrolo(3,2-c)pyridine derivatives as inhibitors of platelet aggregation 136
Lipophilicity of teicoplanin antibiotics as assessed by reversed phase high-performance liquid chromatography: quantitative structure-property and structure-activity relationships 136
An easy, high-yield conversion of aldoximes to nitriles 135
An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes 135
QSAR of Teicoplanin Antibiotics: Influence of Lipophilicity and Ionic Properties on their in vivo Antimicrobial Activity 134
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis 134
Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on Mitsunobu reaction 134
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 134
Sintesi di sistemi eterociclici a potenziale attivita farmacologica contenenti un nucleo 1,3-ossazinico 132
Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 132
A chemocentric approach to the identification of cancer targets 132
Benzenesulfonamide inhibitors of carbonic anhydrase: study of their hydrophobicity by RPLC. 131
Inhibition of MAO by functionalized coumarin derivatives: Biological activities, QSARs and 3D QSARs 130
Neuronal nicotinic acetylcholine receptor agonists: Pharmacophores, evolutionary QSAR and 3D-QSAR models 130
Studio dell’Idrolisi Chimica e Plasmatica di Aril-nipecotati ad Attività Gaba-mimetica Attraverso Analisi Regressionale 129
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 129
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 129
Synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids 128
Actinidin hydrolysis of substituted-phenyl hippurates: a quantitative structure-activity relationship and graphics comparison with hydrolysis by papain 128
SYNTHESIS OF NEW HETEROCYCLIC RING SYSTEMS: INDENO[2,1-B]-BENZO[G]INDOLIZINE AND INDENO[1',2':5,4]PYRROLO[2,1-A]PHTHALAZINE 128
Estimation of the Binding Free Energy by Linear Interaction Energy Models 128
Assessment of Hydrogen-bond Donor Acidity of Bioactive Sulfonyl-containing Compounds by CCC 127
Investigation on platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids 127
Estimation of partitioning parameters of nonionic surfactants using calculated descriptors of molecular size, polarity, and hydrogen bonding. 126
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 125
Synthesis and structure-affinity relationships at the central benzodiazepine receptor of pyridazino4,3-bindoles and indeno1,2-cpyridazines 125
Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors 125
Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. 125
REACH and in silico methods: an attractive opportunity for medicinal chemists 125
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 124
Theoretical Quantitative Structure-Activity Analysis of Quinuclidine-Based Muscarinic Cholinergic Receptor Ligands 123
Tetraoxoderivatives of Perhydropyrrolo[3,4-c]pyridine 123
3,4-Dihydroquinazoline derivatives as T-type Ca2+ channel blockers inhibit the activities of cholinesterase enzymes 123
Folding In Lipid Membranes (FILM): a novel method for the prediction of small membrane protein 3D structures 122
Totale 16.976
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Categoria #
all - tutte 109.576
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 109.576
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.354 0 0 13 98 77 80 94 84 96 166 296 350
2022/20232.861 472 196 147 284 428 362 16 317 520 15 49 55
2023/2024910 80 172 32 142 60 151 30 31 26 27 25 134
2024/20253.397 99 73 351 131 60 236 180 280 186 163 491 1.147
2025/20269.238 1.026 683 2.016 846 679 393 863 261 609 633 235 994
2026/2027872 190 374 308 0 0 0 0 0 0 0 0 0
Totale 30.046