IRIS
FRACCHIOLLA, GIUSEPPE
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 11.118
AS - Asia 4.347
EU - Europa 4.100
SA - Sud America 1.174
Continente sconosciuto - Info sul continente non disponibili 416
AF - Africa 187
OC - Oceania 17
Totale 21.359
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 10.784
SG - Singapore 1.732
IT - Italia 1.531
CN - Cina 1.037
BR - Brasile 924
HK - Hong Kong 512
SE - Svezia 422
RU - Federazione Russa 360
FR - Francia 353
DE - Germania 346
UA - Ucraina 323
VN - Vietnam 262
FI - Finlandia 247
GB - Regno Unito 222
IN - India 190
CA - Canada 142
BD - Bangladesh 109
AR - Argentina 74
TR - Turchia 63
JP - Giappone 54
IQ - Iraq 52
CI - Costa d'Avorio 50
ID - Indonesia 49
MX - Messico 48
CO - Colombia 42
EC - Ecuador 39
BE - Belgio 38
IE - Irlanda 38
NL - Olanda 37
VE - Venezuela 35
ES - Italia 34
SA - Arabia Saudita 34
PL - Polonia 33
ZA - Sudafrica 33
IR - Iran 31
PH - Filippine 30
PK - Pakistan 26
CR - Costa Rica 24
JO - Giordania 21
TT - Trinidad e Tobago 20
UZ - Uzbekistan 20
AT - Austria 19
CL - Cile 19
NI - Nicaragua 19
GT - Guatemala 17
KR - Corea 17
TN - Tunisia 17
JM - Giamaica 16
KE - Kenya 16
IL - Israele 15
AU - Australia 14
MY - Malesia 14
CH - Svizzera 13
EG - Egitto 13
PE - Perù 13
SV - El Salvador 13
CZ - Repubblica Ceca 12
MA - Marocco 12
LT - Lituania 11
PR - Porto Rico 11
PY - Paraguay 10
BO - Bolivia 9
DZ - Algeria 9
NP - Nepal 9
SC - Seychelles 9
HN - Honduras 8
LB - Libano 8
RO - Romania 8
CW - ???statistics.table.value.countryCode.CW??? 7
KG - Kirghizistan 7
KZ - Kazakistan 6
OM - Oman 6
SN - Senegal 6
UY - Uruguay 6
BG - Bulgaria 5
GE - Georgia 5
GP - Guadalupe 5
MD - Moldavia 5
PT - Portogallo 5
RS - Serbia 5
AZ - Azerbaigian 4
BH - Bahrain 4
EE - Estonia 4
ET - Etiopia 4
GR - Grecia 4
AE - Emirati Arabi Uniti 3
AM - Armenia 3
AO - Angola 3
BA - Bosnia-Erzegovina 3
EU - Europa 3
KW - Kuwait 3
NO - Norvegia 3
PS - Palestinian Territory 3
SI - Slovenia 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
TW - Taiwan 3
XK - ???statistics.table.value.countryCode.XK??? 3
A1 - Anonimo 2
AL - Albania 2
Totale 20.903
Salva come PNG Salva come JPEG
Città #
Ashburn 1.281
Singapore 883
San Jose 823
Jacksonville 721
Chandler 692
Fairfield 635
Woodbridge 572
Hong Kong 505
Milan 475
Houston 400
Cambridge 343
Council Bluffs 304
Nyköping 298
Dallas 294
Ann Arbor 281
Seattle 274
Beijing 243
Wilmington 237
Bari 232
Rome 177
Lawrence 174
Roxbury 171
Lauterbourg 163
New York 158
Nanjing 156
Los Angeles 145
Boardman 141
Princeton 137
Des Moines 108
Santa Clara 103
Ho Chi Minh City 101
Washington 98
São Paulo 94
Inglewood 81
Helsinki 75
Buffalo 61
Chicago 56
Hanoi 55
Brooklyn 51
Abidjan 50
Figino 50
Nanchang 49
Munich 47
Frankfurt am Main 44
Toronto 44
Tokyo 42
Hebei 41
Brussels 38
Dublin 37
Jiaxing 37
Dearborn 33
London 33
Orem 33
San Diego 33
Phoenix 32
Rio de Janeiro 32
Tianjin 32
Changsha 31
Columbus 30
Turin 30
Shenyang 29
Atlanta 28
Marseille 28
San Francisco 28
Mumbai 27
Chennai 26
Paris 26
Belo Horizonte 25
Guangzhou 24
Moscow 24
Warsaw 24
Istanbul 23
Montreal 23
Baghdad 22
Denver 22
Naples 22
Jakarta 21
Stockholm 21
Bologna 20
Leawood 20
North Bergen 20
Tashkent 20
Amman 19
Wuhan 19
Augusta 18
Falkenstein 18
Managua 18
San José 18
Nuremberg 17
Manchester 16
Quito 16
Taranto 16
Amsterdam 15
Brasília 15
Caracas 15
Johannesburg 15
Campinas 14
Curitiba 14
Dhaka 14
Guayaquil 14
Totale 13.410
Salva come PNG Salva come JPEG
Nome #
Antibiotics - Mentha piperita essential oil synergism inhinibts mature bacterial biofilm 295
Probiotic and Tea Tree Oil Treatments Improve Therapy of Vaginal Candidiasis: A Preliminary Clinical Study 268
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 230
Virucidal activity of ginger essential oil against caprine alphaherpesvirus-1 226
An efficient synthesis of the optically active isomers of 2H-1,4-benzoxazine derivatives, novel KATP channel modulators 220
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of CLC-Kb channels 201
Slightly viscous dispersions of mucoadhesive polymers as vehicles for nasal administration of dopamine and grape seed extract-loaded solid lipid nanoparticles 196
Activation and inhibition of kidney CLC-K chloride channels by fenamates 195
Synthesis, in vitro evaluation, and molecular modeling investigation of benzenesulfonimide peroxisome proliferator-activated receptors α antagonists 192
Nose-to-Brain delivery of dopamine via nanocarriers or polymer conjugates: a comparative study 187
Kidney CLC-K Chloride Channels Show Differential Pharmacological Profiles Depending on the Heterologous Expression System 178
Anti-biofilm inhibitory synergistic effects of combinations of essential oils and antibiotics 174
ChemInform Abstract: Convenient Synthesis of Some 3-Phenyl-1-benzofuran-2-carboxylic Acid Derivatives as New Potential Inhibitors of CLC-Kb Channels. 173
The effect of nitrogen atoms in the enantioselective oxidation of aryl or heteroaryl benzyl sulfides 167
Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity 166
A Study of Factors Affecting Enantioselectivity in the Oxidation of Aryl Benzyl Sulfides in the Presence of Chiral Titanium Catalysts 165
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 164
Antimicrobial Activity of Essential Oils Evaluated In Vitro against Escherichia coli and Staphylococcus aureus 159
ANTIDIABETIC AND ANTIOBESITY ACTIVITY OF A NOVEL DUAL PEROXYSOME PROLIFERATOR ACTIVATED RECEPTORS ALPHA/GAMMA LIGAND: A NEW SCAFFOLD MOLECULE DEVOID OF SOME SIDE-EFFECTS OF PPAR LIGANDS? 158
A novel approach to the synthesis of dialkyl or aryl alkyl sulfoxides in high enantiomeric purity 158
Chemical composition and antibacterial activity of seven uncommon essential oils 155
Repositioning of Endonuclear Receptors Binders as Potential Antibacterial and Antifungal Agents. Eptyloxìm: A Potential and Novel Gyrase B and Cytochrome Cyp51 Inhibitor 154
Procedimento e apparecchiatura per la misurazione del potere anti-infiammatorio di matrici alimentari complesse 151
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 149
Antifungal Biofilm Inhibitory Effects of Combinations of Diclofenac and Essential Oils 149
A novel carbon leaving group in the reaction of organometallic compounds with phosphine oxides 145
Combined Dopamine and Grape Seed Extract-Loaded Solid Lipid Nanoparticles: Nasal Mucosa Permeation, and Uptake by Olfactory Ensheathing Cells and Neuronal SH-SY5Y Cells 145
AGONISTI DEI RECETTORI NUCLEARI PPARs COME POTENZIALI NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DELLA SINDROME METABOLICA. 144
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection 143
Analoghi degli acidi clofibrici e loro uso come ligandi dei recettori nucleari peroxisome proliferator activated receptor (PPAR) alfa e gamma 142
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression 139
Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: A new region of the hydrophobic pocket could be exploited for drug design 139
AFFINITY OF NEW CHIRAL ARYLOXYALKYLPIPERIDINES TOWARDS σ RECEPTOR SUBTYPES. 138
Elucidation of the synergistic action of Mentha Piperita essential oil with common antimicrobials 138
A novel strategy for the synthesis of chiral nonracemic sulfoxides based upon the displacement of carbanionic leaving groups by organometallic reagents. 136
Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels 136
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor alpha/gamma ligand LT175 136
Agonisti dei Recettori Nucleari PPARs come Potenziali Nuovi Agenti Terapeutici per il Trattamento della Sindrome Metabolica 134
Enantioselective hydrolysis of some 2-aryloxyalkanoic acid methyl esters and isosteric analogues using a penicillin G acylase-based HPLC monolithic silica column 133
(contributo in convegno) MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY; CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 132
Diclofenac sodico in associazione con alcuni oli essenziali: evidenza sperimentale in vitro dell'azione sinergica antibiofilm verso diverse specie fungine appartenenti al genere Candida. VI° Congresso Nazionale della Società Italiana per la Ricerca sugli Oli Essenziali. 18-19 ottobre 2019. Dipartimento di Scienze Agro Alimentari dell'Università degli Studi di Bologna. 131
Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus 131
Non-Antibiotic Drug Repositioning as an Alternative Antimicrobial Approach 130
ChemInform Abstract: Enantioselective Catalytic Oxidation of (Arylthio)- or (Alkylthio)methylphosphonates as a Route to Enantiomeric Pure Aryl Alkyl or Dialkyl Sulfoxides. 130
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity. 130
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction. 129
Dopamine - and Grape-Seed-Extract-Loaded Solid Lipid Nanoparticles: Interaction Studies between Particles and Differentiated SH-SY5Y Neuronal Cell Model of Parkinson’s Disease 128
Synthesis, Biological Evaluation, and Molecular Modeling Investigation of Chiral Phenoxyacetic Acid Analogues with PPARalpha and PPARgamma Agonist Activity 128
Kidney CLC-K chloride channels inhibitors: structure-based studies and efficacy in hypertension and associated CLC-K polymorphisms. 128
In-vivo administration of CLC-K kidney chloride channels inhibitors increases water diuresis in rats: A new drug target for hypertension? 128
Allyphenyline Analogues Potentially Useful in the Management of Chronic Pain and Opioid Addiction 127
Carboxymethyl chitosan dopamine conjugates: Synthesis and evaluation for intranasal anti Parkinson therapy 124
Dopamine and Antioxidant Grape Seed Extract loaded chitosan nanoparticles: A preliminary in vitro characterization 124
ChemInform Abstract: Enantio- or Diastereoselective Oxidation of (Methylthio)methylphosphonates as a Route to Precursors of Chiral Sulfoxides. 124
MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY: CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 124
Molecular determinants of 2(p-chlorophenoxy)propionic acid for modulation of the native chloride channel conductance of rat skeletal muscle 124
Calcium activated K+ channel as a target of prompt-to-use drugs in neuromuscular disorders 124
Enantioselective catalytic oxidation of (arylthio)- or (alkylthio)methylphosphonates as a route to enantiomeric pure aryl alkyl or dialkyl sulfoxides 124
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation 124
Analisi conduttimetrica 122
Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases 120
CLC-K kidney chloride channels as drug target for hypertension: effects of acute in vivo administration to rats of newly synthesized inhibitors 120
Block of renal CLC-K channels by phenoxy-alkyl derivatives of clofibric acid 117
Antioxidant based Solid Lipid Nanoparticles: in vitro studies on the administration of citicoline for supporting anti-Parkinson therapy 116
Studio delle proprietà enentioselettive di una fase stazionaria chirale a base di PGA 115
Enantiomeric separation of 2-aryloxyalkyl- and 2-arylalkyl-2-aryloxyacetic acids on a Penicillin G Acylase-based chiral stationary phase: influence of the chemical structure on retention and enantioselectivity 115
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers 112
Elucidation of the enantioselective recognition mechanism of a penicillin G acylase-based chiral stationary phase towards a series of 2-aryloxy-2-arylacetic acids 112
Changing the binding mode to peroxisome proliferator activated receptor (PPAR) alpha/gamma: a new ligand with improved antidiabetic and antiobesity properties 112
Solid Lipid Nanoparticles Containing Dopamine and Grape Seed Extract: Freeze-Drying with Cryoprotection as a Formulation Strategy to Achieve Nasal Powders 111
Improved lipid metabolism and reduced fat deposition in a mouse model of diet-induced obesity (DIO) with a new dual PPARα/γ ligand 111
BIOLOGICAL ACTIVITY OF NEW POTENT 2H-1,4-BENZOXAZINE DERIVATIVES ON THE NATIVE SKELETAL MUSCLE KATP CHANNEL 111
Attività biologica sui canali KATP del muscolo scheletrico nativo di nuovi e potenti derivati delle 2H-1,4-Benzossazine 111
Might the observed a2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? 111
VARIOUS MEMBERS OF CLC FAMILY ARE DIFFERENTLY AFFECTED BY NEWLY SYNTHESIZED CLOFIBRIC ACID DERIVATIVES. 110
Exploring the Antibiofilm Effect of Sertraline in Synergy with Cinnamomum verum Essential Oil to Counteract Candida Species 109
KIDNEY CLC-K CHLORIDE CHANNELS SHOW DIFFERENTIAL PHARMACOLOGICAL PROFILES DEPENDING ON THE HETEROLOGOUS EXPRESSION SYSTEM 109
Exploring the molecular basis of the enantioselective binding of penicillin G acylase towards a series of 2 aryloxyalkanoic acids: A docking and molecular dynamics study 109
Attività di nuovi analoghi chirali dell'acido clofibrico sui canali al cloro ClC-1 108
Structural nucleotide analogs are potent activators/inhibitors of pancreatic beta-cell KATP channels: an emerging mechanism supporting their use as anti-diabetic drugs. 108
Valutazione dell’attività biologica di acidi arilossiacetici a-sostituiti e relativi isosteri 107
Molecular determinants of 2(p-chlorophenoxy)propionic acid for modulation of the native chloride channel conductance of rat skeletal muscle 106
Virucidal Activity of Lemon Essential Oil against Feline Calicivirus Used as Surrogate for Norovirus 103
Niflumic acid derivatives modulate macroscopic chloride conductance of native rat skeletal muscle by inhibiting the CLC-1 channel and by increasing the intracellular calcium level 103
Affinity of new chiral aryloxyalkylpiperidines towards sigma receptors 103
Antibiofilm Effects of Plant Extracts Against Staphylococcus aureus 102
Sintesi e valutazione biologica di nuovi solfonil fosfonati come inibitori di metalloproteinasi di matrice 102
Evaluation of a penicillin G acylase-based chiral stationary phase towards a series of 2-aryloxyalkanoic acids, isosteric analogs and 2-arylpropionic acids 102
Combining Inorganic Antibacterial Nanophases and Essential Oils: Recent Findings and Prospects 101
Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors alpha/gamma agonists 101
Benzothiazole-Containing Analogues of Triclocarban with Potent Antibacterial Activity 101
Gruppi uscenti di natura carbanionica nelle reazioni di solfossidi e fosfinossidi con reattivi di Grignard. 100
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists 98
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid 98
Sintesi di una nuova serie di acidi 2-benzofuran-carbossilici a potenziale attività bloccante dei canali al cloro voltaggio-dipendenti CLC-K 97
Characterization of two synthetic ligands of peroxisome proliferator-activated receptor (PPAR) by cofactor recruitment, site-directed mutagenesis and structure analysis 96
Synergistic Action of Cinnamomum verum Essential Oil with Sertraline 96
INNOVATIVE METHODOLOGIES IN NANOTECHNOLOGY FOR THE PREVENTION OF BACTERIAL DISEASES 95
H-1-NMR determination of the enantiomeric excess of the antiarrhythmic drug Mexiletine by using mandelic acid analogues as chiral solvating agents 94
Solid Lipid Nanoparticles for delivery of Dopamine and Grape Seed Extracts in differentiated SH-SY5Y neuronal cell model of Parkinson disease. 93
Totale 13.489
Salva come PNG Salva come JPEG
Categoria #
all - tutte 86.639
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 86.639
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022937 0 0 0 0 49 48 54 51 54 55 223 403
2022/20231.992 347 126 107 178 286 262 20 197 376 12 42 39
2023/2024968 67 141 62 59 94 201 40 64 40 53 37 110
2024/20252.940 111 61 255 164 74 218 186 280 151 146 398 896
2025/20266.674 860 375 493 736 613 376 801 226 604 585 178 827
2026/20272.314 170 365 786 932 61 0 0 0 0 0 0 0
Totale 21.359