IRIS
LENTINI, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 16.458
AS - Asia 7.314
EU - Europa 6.518
SA - Sud America 1.728
AF - Africa 364
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 6
Totale 32.411
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Nazione #
US - Stati Uniti d'America 16.150
SG - Singapore 3.046
IT - Italia 2.200
CN - Cina 1.652
BR - Brasile 1.329
HK - Hong Kong 959
SE - Svezia 822
RU - Federazione Russa 649
UA - Ucraina 595
DE - Germania 583
FI - Finlandia 514
FR - Francia 450
VN - Vietnam 389
GB - Regno Unito 304
IN - India 244
BD - Bangladesh 205
CA - Canada 149
AR - Argentina 129
TR - Turchia 119
CI - Costa d'Avorio 113
ID - Indonesia 104
IQ - Iraq 86
MX - Messico 86
ZA - Sudafrica 81
JP - Giappone 72
CO - Colombia 64
PK - Pakistan 61
ES - Italia 55
SA - Arabia Saudita 49
EC - Ecuador 48
NL - Olanda 47
PH - Filippine 45
BE - Belgio 44
IE - Irlanda 44
PL - Polonia 43
VE - Venezuela 43
UZ - Uzbekistan 40
MA - Marocco 39
MY - Malesia 39
AT - Austria 32
UY - Uruguay 28
CL - Cile 27
LT - Lituania 25
KE - Kenya 23
PY - Paraguay 23
IR - Iran 21
TN - Tunisia 21
EG - Egitto 19
ET - Etiopia 19
PE - Perù 18
TH - Thailandia 18
AU - Australia 17
BO - Bolivia 17
AZ - Azerbaigian 15
JO - Giordania 14
AE - Emirati Arabi Uniti 13
JM - Giamaica 13
KR - Corea 13
RO - Romania 13
CR - Costa Rica 11
NP - Nepal 11
PS - Palestinian Territory 11
TT - Trinidad e Tobago 11
CZ - Repubblica Ceca 10
KG - Kirghizistan 10
OM - Oman 10
PA - Panama 10
PT - Portogallo 10
RS - Serbia 10
DZ - Algeria 9
GE - Georgia 8
IL - Israele 8
NI - Nicaragua 8
TW - Taiwan 8
BY - Bielorussia 7
LB - Libano 7
AL - Albania 6
AO - Angola 6
DO - Repubblica Dominicana 6
KW - Kuwait 6
KZ - Kazakistan 6
LV - Lettonia 6
NZ - Nuova Zelanda 6
SN - Senegal 6
BH - Bahrain 5
GR - Grecia 5
LY - Libia 5
NG - Nigeria 5
QA - Qatar 5
SI - Slovenia 5
BG - Bulgaria 4
EE - Estonia 4
EU - Europa 4
HN - Honduras 4
HU - Ungheria 4
KH - Cambogia 4
MD - Moldavia 4
NO - Norvegia 4
AM - Armenia 3
BB - Barbados 3
Totale 32.355
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Città #
Singapore 1.600
Ashburn 1.493
Fairfield 1.325
Jacksonville 1.319
Chandler 1.213
San Jose 1.010
Woodbridge 965
Hong Kong 949
Milan 776
Houston 712
Dallas 597
Nyköping 587
Cambridge 529
Seattle 518
Wilmington 457
Ann Arbor 406
Beijing 386
Roxbury 298
New York 296
Lauterbourg 293
Lawrence 292
Nanjing 292
Rome 248
Los Angeles 236
Bari 229
Helsinki 216
Boardman 206
Des Moines 193
Princeton 164
Santa Clara 150
Ho Chi Minh City 120
Brooklyn 117
Abidjan 113
São Paulo 109
Council Bluffs 90
Buffalo 88
Munich 82
San Diego 78
Hanoi 74
Columbus 73
Hebei 73
Shenyang 71
Nanchang 69
Inglewood 66
Tokyo 66
London 65
Jiaxing 59
Figino 58
Chicago 57
Moscow 57
Jakarta 54
Rio de Janeiro 50
Atlanta 48
Frankfurt am Main 47
Orem 47
Turin 47
Dearborn 44
Falkenstein 42
Guangzhou 42
Dublin 41
San Francisco 41
Brussels 39
Warsaw 39
Johannesburg 38
Pune 38
Changsha 36
Baghdad 35
Montreal 35
North Bergen 32
Tashkent 32
Tianjin 32
Chennai 31
Denver 31
Toronto 31
Dhaka 29
Istanbul 29
Paris 29
Phoenix 29
Turku 29
Mexico City 28
Naples 27
Stockholm 27
Dong Ket 24
Jinan 24
Redwood City 24
Amsterdam 23
Belo Horizonte 23
Da Nang 23
Medellín 23
Porto Alegre 23
Montevideo 22
Riyadh 22
Bologna 21
Manchester 21
Marseille 21
Shanghai 21
Brasília 20
Poplar 20
Salvador 20
Haiphong 19
Totale 21.113
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Nome #
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 256
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 245
Acidi carbossilici derivati dell'antracene e suoi isosteri: effetti sulla conduttanza al cloro 225
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 215
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 215
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 208
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 201
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 190
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 190
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 183
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 183
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 178
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 177
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin 175
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 175
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 174
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 174
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine 173
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 172
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 168
The therapeutic potential of rutin for diabetes: An update 165
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 164
The chemistry and pharmacology of citrus limonoids 163
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 163
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 162
Old drug scaffold, new activity: Thalidomide-correlated compounds exert different effects on breast cancer cell growth and progression 161
Hypoglycemic properties of Leccinum scabrum - An in vitro study on α-glucosidase and α-amylase inhibition activity 160
2-(9-Antryl)alcanoic acids as chloride channel modulators 159
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 159
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 158
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 158
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 157
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 155
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 153
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 153
A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli 152
Le applicazioni della chimica farmaceutica 152
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 152
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 151
Enzymatic Resolution of α-Methyleneparaconic Acids and Evaluation of their Biological Activity 151
Positional isomers of mannose-quinoline conjugates and their copper complexes: Exploring the biological activity 148
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 147
Facile entry to (-)-R- and (+)-(S)-mexiletine 144
Recent trends in the discovery of small molecule blockers of sodium channels 144
The practice of medicinal chemistry 143
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 143
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 141
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 139
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 138
New doxorubicin nanocarriers based on cyclodextrins 137
Pharmacological differences between R(-) and S(+) Tocainide 135
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 135
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 134
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 134
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 133
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 132
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 130
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 130
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 129
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 128
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 128
Alpha-glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 128
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 128
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 128
Analoghi chirali della mexiletina: blocco stereoselettivo dei canali per gli ioni sodio e ipotesi sull’interazione recettoriale 127
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 127
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 127
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 127
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypothesis on mechanism of action. 125
Targeting the pregnane X receptor using microbial metabolite mimicry 125
a-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 124
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 124
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 124
The effects of tocainide and its chiral analogs on sodium channels of human muscle 123
Pharmacological differences between R(-) and S(+) Tocainide 123
An Introduction to Medicinal Chemistry 122
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 121
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 121
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 120
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 120
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 119
Analisi Farmaceutica 119
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 119
2,6-Xilididi e beta-2,6-xililosietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 118
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 118
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 117
Trivial, common, and systematic chemical names 117
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 117
Comment on "in Situ Derivatization of (RS)-Mexiletine and Enantioseparation Using Micellar Liquid Chromatography: A Green Approach" 117
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 116
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 115
Structure-Based Identification and Design of Angiotensin Converting Enzyme-Inhibitory Peptides from Whey Proteins 115
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 114
Proprietà antiossidanti dell'uva di troia canosina ad acino piccolo: confronto tra diversi metodi estrattivi 114
Analoghi chirali della Tocainide: attività analgesica centrale 114
Lubeluzole: from anti-ischemic to chemosensitizing agent 114
Stereospecific synthesis and absolute configuration of Mexiletine 113
Phytochemical, Antioxidant and Anti-a-glucosidase Activity Evaluations of Bergenia cordifolia 113
Pharmacological differences between R(-) and S(+) tocainide 112
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 112
Totale 14.574
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Categoria #
all - tutte 132.853
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 132.853
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.987 89 333 36 96 48 100 71 98 115 118 308 575
2022/20233.285 541 282 170 303 429 438 31 392 521 24 84 70
2023/20241.316 94 230 52 98 67 282 35 74 35 45 149 155
2024/20255.018 167 105 449 162 129 382 389 493 260 260 694 1.528
2025/202611.953 1.458 441 1.101 1.198 1.132 709 1.460 317 1.026 1.042 428 1.641
2026/2027327 327 0 0 0 0 0 0 0 0 0 0 0
Totale 33.042