IRIS
LENTINI, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 15.934
AS - Asia 7.255
EU - Europa 5.184
SA - Sud America 1.704
AF - Africa 364
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 6
Totale 30.470
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Nazione #
US - Stati Uniti d'America 15.655
SG - Singapore 3.043
CN - Cina 1.644
BR - Brasile 1.317
HK - Hong Kong 957
IT - Italia 892
SE - Svezia 822
RU - Federazione Russa 649
UA - Ucraina 593
DE - Germania 582
FI - Finlandia 514
FR - Francia 443
VN - Vietnam 389
GB - Regno Unito 300
IN - India 242
BD - Bangladesh 162
CA - Canada 132
AR - Argentina 124
TR - Turchia 119
CI - Costa d'Avorio 113
ID - Indonesia 103
IQ - Iraq 86
MX - Messico 84
ZA - Sudafrica 81
JP - Giappone 72
PK - Pakistan 61
CO - Colombia 60
ES - Italia 52
SA - Arabia Saudita 49
EC - Ecuador 48
NL - Olanda 47
PH - Filippine 45
IE - Irlanda 44
PL - Polonia 43
BE - Belgio 41
VE - Venezuela 41
UZ - Uzbekistan 40
MA - Marocco 39
MY - Malesia 39
AT - Austria 32
UY - Uruguay 28
CL - Cile 26
LT - Lituania 25
KE - Kenya 23
PY - Paraguay 23
IR - Iran 21
TN - Tunisia 21
EG - Egitto 19
ET - Etiopia 19
PE - Perù 18
TH - Thailandia 18
AU - Australia 17
BO - Bolivia 17
AZ - Azerbaigian 15
JO - Giordania 14
AE - Emirati Arabi Uniti 13
KR - Corea 13
RO - Romania 12
CR - Costa Rica 11
JM - Giamaica 11
NP - Nepal 11
PS - Palestinian Territory 11
KG - Kirghizistan 10
OM - Oman 10
PA - Panama 10
PT - Portogallo 10
TT - Trinidad e Tobago 10
CZ - Repubblica Ceca 9
DZ - Algeria 9
RS - Serbia 9
GE - Georgia 8
IL - Israele 8
TW - Taiwan 8
BY - Bielorussia 7
LB - Libano 7
AL - Albania 6
AO - Angola 6
DO - Repubblica Dominicana 6
KW - Kuwait 6
KZ - Kazakistan 6
LV - Lettonia 6
NI - Nicaragua 6
NZ - Nuova Zelanda 6
SN - Senegal 6
BH - Bahrain 5
LY - Libia 5
NG - Nigeria 5
QA - Qatar 5
SI - Slovenia 5
EE - Estonia 4
EU - Europa 4
GR - Grecia 4
HU - Ungheria 4
KH - Cambogia 4
MD - Moldavia 4
NO - Norvegia 4
AM - Armenia 3
BB - Barbados 3
BG - Bulgaria 3
CH - Svizzera 3
Totale 30.419
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Città #
Singapore 1.599
Ashburn 1.460
Fairfield 1.326
Jacksonville 1.316
Chandler 1.213
San Jose 990
Woodbridge 965
Hong Kong 947
Houston 711
Dallas 593
Nyköping 587
Cambridge 529
Seattle 518
Wilmington 457
Ann Arbor 406
Beijing 383
Roxbury 298
Lauterbourg 293
Lawrence 292
Nanjing 292
New York 286
Los Angeles 230
Bari 221
Helsinki 216
Des Moines 193
Boardman 167
Princeton 164
Santa Clara 131
Ho Chi Minh City 120
Brooklyn 116
Abidjan 113
São Paulo 107
Council Bluffs 90
Munich 82
Buffalo 81
San Diego 78
Hanoi 74
Hebei 73
Shenyang 71
Nanchang 69
Inglewood 66
Tokyo 66
London 64
Jiaxing 59
Moscow 57
Chicago 54
Jakarta 54
Rio de Janeiro 48
Frankfurt am Main 46
Orem 46
Dearborn 44
Atlanta 42
Falkenstein 42
Guangzhou 42
Dublin 41
Rome 40
Brussels 39
San Francisco 39
Warsaw 39
Johannesburg 38
Pune 38
Changsha 36
Baghdad 35
Tashkent 32
Tianjin 32
Chennai 31
Denver 31
Montreal 31
North Bergen 30
Toronto 30
Dhaka 29
Istanbul 29
Turku 29
Paris 28
Mexico City 27
Milan 27
Phoenix 27
Stockholm 27
Dong Ket 24
Jinan 24
Redwood City 24
Amsterdam 23
Belo Horizonte 23
Da Nang 23
Porto Alegre 23
Montevideo 22
Riyadh 22
Manchester 21
Marseille 21
Medellín 21
Shanghai 21
Brasília 20
Columbus 20
Poplar 20
Salvador 20
Haiphong 19
Kuala Lumpur 19
Lahore 19
San Mateo 19
The Dalles 19
Totale 19.839
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Nome #
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 229
Acidi carbossilici derivati dell'antracene e suoi isosteri: effetti sulla conduttanza al cloro 218
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 210
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 206
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 200
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 181
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 181
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 180
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 176
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 174
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin 173
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 171
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 168
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 167
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 164
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 164
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 163
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 161
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine 161
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 160
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 156
The therapeutic potential of rutin for diabetes: An update 156
The chemistry and pharmacology of citrus limonoids 156
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 156
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 155
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 155
Hypoglycemic properties of Leccinum scabrum - An in vitro study on α-glucosidase and α-amylase inhibition activity 154
Old drug scaffold, new activity: Thalidomide-correlated compounds exert different effects on breast cancer cell growth and progression 154
2-(9-Antryl)alcanoic acids as chloride channel modulators 151
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 151
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 148
Enzymatic Resolution of α-Methyleneparaconic Acids and Evaluation of their Biological Activity 147
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 146
Le applicazioni della chimica farmaceutica 146
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 146
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 146
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 144
Positional isomers of mannose-quinoline conjugates and their copper complexes: Exploring the biological activity 144
Facile entry to (-)-R- and (+)-(S)-mexiletine 143
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 143
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 142
Recent trends in the discovery of small molecule blockers of sodium channels 142
The practice of medicinal chemistry 138
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 138
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 138
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 136
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 136
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 130
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 129
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 129
Pharmacological differences between R(-) and S(+) Tocainide 127
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 127
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 127
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 127
New doxorubicin nanocarriers based on cyclodextrins 127
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 127
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 127
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 126
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 124
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 124
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 123
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 123
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 123
Pharmacological differences between R(-) and S(+) Tocainide 122
Alpha-glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 122
Analoghi chirali della mexiletina: blocco stereoselettivo dei canali per gli ioni sodio e ipotesi sull’interazione recettoriale 120
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 120
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 120
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypothesis on mechanism of action. 119
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 119
Targeting the pregnane X receptor using microbial metabolite mimicry 118
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 117
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 117
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 116
An Introduction to Medicinal Chemistry 116
The effects of tocainide and its chiral analogs on sodium channels of human muscle 115
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 115
Comment on "in Situ Derivatization of (RS)-Mexiletine and Enantioseparation Using Micellar Liquid Chromatography: A Green Approach" 115
Structure-Based Identification and Design of Angiotensin Converting Enzyme-Inhibitory Peptides from Whey Proteins 115
a-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 114
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 114
Lubeluzole: from anti-ischemic to chemosensitizing agent 114
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 113
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 112
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 112
Analoghi chirali della Tocainide: attività analgesica centrale 112
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 112
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 111
Analisi Farmaceutica 111
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 111
2,6-Xilididi e beta-2,6-xililosietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 110
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 110
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation 110
Trivial, common, and systematic chemical names 109
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 108
Stereospecific synthesis and absolute configuration of Mexiletine 108
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs 108
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 107
Newly synthesized mexiletine and tocainide analogues are potent use-dependent blockers of skeletal muscle sodium channels: potential implication for antimyotonic activity 107
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: Hypothesis on mechanism of action 107
Totale 13.800
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Categoria #
all - tutte 126.745
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 126.745
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021151 0 0 0 0 0 0 0 0 0 0 0 151
2021/20221.987 89 333 36 96 48 100 71 98 115 118 308 575
2022/20233.285 541 282 170 303 429 438 31 392 521 24 84 70
2023/20241.316 94 230 52 98 67 282 35 74 35 45 149 155
2024/20255.018 167 105 449 162 129 382 389 493 260 260 694 1.528
2025/202610.331 1.458 441 1.101 1.198 1.132 709 1.460 317 1.028 1.044 431 12
Totale 31.093