IRIS
LENTINI, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 19.349
AS - Asia 7.386
EU - Europa 6.633
SA - Sud America 1.805
Continente sconosciuto - Info sul continente non disponibili 641
AF - Africa 368
OC - Oceania 23
Totale 36.205
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Nazione #
US - Stati Uniti d'America 18.942
SG - Singapore 3.050
IT - Italia 2.263
CN - Cina 1.662
BR - Brasile 1.374
HK - Hong Kong 962
SE - Svezia 823
RU - Federazione Russa 650
UA - Ucraina 597
DE - Germania 594
FI - Finlandia 514
FR - Francia 453
VN - Vietnam 393
GB - Regno Unito 322
IN - India 248
BD - Bangladesh 221
CA - Canada 199
AR - Argentina 135
TR - Turchia 122
CI - Costa d'Avorio 114
ID - Indonesia 114
MX - Messico 92
IQ - Iraq 86
ZA - Sudafrica 81
JP - Giappone 75
CO - Colombia 72
PK - Pakistan 63
EC - Ecuador 58
ES - Italia 57
SA - Arabia Saudita 51
PH - Filippine 49
VE - Venezuela 49
NL - Olanda 48
BE - Belgio 45
PL - Polonia 45
IE - Irlanda 44
MY - Malesia 40
UZ - Uzbekistan 40
MA - Marocco 39
AT - Austria 32
UY - Uruguay 29
CL - Cile 27
LT - Lituania 27
KE - Kenya 24
PY - Paraguay 24
JM - Giamaica 23
IR - Iran 21
TN - Tunisia 21
TH - Thailandia 20
CR - Costa Rica 19
EG - Egitto 19
ET - Etiopia 19
PE - Perù 18
AU - Australia 17
BO - Bolivia 17
AZ - Azerbaigian 15
RO - Romania 15
TT - Trinidad e Tobago 15
JO - Giordania 14
AE - Emirati Arabi Uniti 13
KR - Corea 13
NP - Nepal 12
PA - Panama 12
HN - Honduras 11
NI - Nicaragua 11
PS - Palestinian Territory 11
CZ - Repubblica Ceca 10
KG - Kirghizistan 10
OM - Oman 10
PT - Portogallo 10
RS - Serbia 10
DZ - Algeria 9
IL - Israele 9
TW - Taiwan 9
GE - Georgia 8
BY - Bielorussia 7
EE - Estonia 7
KZ - Kazakistan 7
LB - Libano 7
AL - Albania 6
AO - Angola 6
DO - Repubblica Dominicana 6
KW - Kuwait 6
LV - Lettonia 6
NZ - Nuova Zelanda 6
SN - Senegal 6
BG - Bulgaria 5
BH - Bahrain 5
GR - Grecia 5
LY - Libia 5
NG - Nigeria 5
QA - Qatar 5
SI - Slovenia 5
DK - Danimarca 4
EU - Europa 4
HR - Croazia 4
HU - Ungheria 4
KH - Cambogia 4
MD - Moldavia 4
NO - Norvegia 4
Totale 35.503
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Città #
Ashburn 2.169
Singapore 1.602
San Jose 1.428
Fairfield 1.325
Jacksonville 1.319
Chandler 1.213
Woodbridge 966
Hong Kong 952
Milan 780
Houston 713
Dallas 628
Nyköping 587
Cambridge 530
Seattle 526
Wilmington 459
Council Bluffs 453
Ann Arbor 407
Beijing 392
New York 329
Roxbury 298
Lauterbourg 293
Lawrence 292
Nanjing 292
Los Angeles 271
Rome 255
Bari 232
Helsinki 216
Boardman 208
Santa Clara 202
Des Moines 194
Princeton 164
São Paulo 143
Columbus 125
Ho Chi Minh City 123
Washington 123
Brooklyn 119
Abidjan 114
Buffalo 93
Chicago 84
Munich 82
San Diego 78
Hanoi 74
Hebei 73
Shenyang 71
Nanchang 69
Tokyo 68
London 67
Inglewood 66
Atlanta 63
Jiaxing 59
Figino 58
Phoenix 58
Moscow 57
Jakarta 54
Frankfurt am Main 52
Rio de Janeiro 51
San Francisco 50
Toronto 50
Orem 48
Turin 48
Dearborn 44
Falkenstein 42
Guangzhou 42
Montreal 42
Dublin 41
Brussels 39
Warsaw 39
Denver 38
Johannesburg 38
Pune 38
Changsha 36
Baghdad 35
North Bergen 35
The Dalles 35
Tashkent 32
Tianjin 32
Chennai 31
Istanbul 30
Mexico City 30
Dhaka 29
Paris 29
Turku 29
Stockholm 28
Naples 27
Belo Horizonte 24
Bologna 24
Dong Ket 24
Jinan 24
Medellín 24
Redwood City 24
Amsterdam 23
Da Nang 23
Miami 23
Porto Alegre 23
Montevideo 22
Riyadh 22
Brasília 21
Manchester 21
Marseille 21
Shanghai 21
Totale 23.120
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Nome #
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 322
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 275
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 275
Acidi carbossilici derivati dell'antracene e suoi isosteri: effetti sulla conduttanza al cloro 250
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 227
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 215
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 209
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 207
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 207
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 198
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 194
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 192
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 187
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 186
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 184
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 183
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 182
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 182
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine 180
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin 180
The therapeutic potential of rutin for diabetes: An update 179
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 176
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 173
The chemistry and pharmacology of citrus limonoids 171
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 171
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 170
Hypoglycemic properties of Leccinum scabrum - An in vitro study on α-glucosidase and α-amylase inhibition activity 169
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 169
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 168
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 167
Old drug scaffold, new activity: Thalidomide-correlated compounds exert different effects on breast cancer cell growth and progression 167
A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli 166
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 166
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 166
2-(9-Antryl)alcanoic acids as chloride channel modulators 165
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 164
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 164
Facile entry to (-)-R- and (+)-(S)-mexiletine 163
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction 159
Enzymatic Resolution of α-Methyleneparaconic Acids and Evaluation of their Biological Activity 158
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 157
Le applicazioni della chimica farmaceutica 156
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 153
Positional isomers of mannose-quinoline conjugates and their copper complexes: Exploring the biological activity 153
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemiareperfusion injury, searching for new pharmacological targets 150
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 150
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 150
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 148
The practice of medicinal chemistry 148
Alpha-glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 147
Recent trends in the discovery of small molecule blockers of sodium channels 147
New doxorubicin nanocarriers based on cyclodextrins 146
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 143
Analoghi chirali della mexiletina: blocco stereoselettivo dei canali per gli ioni sodio e ipotesi sull’interazione recettoriale 143
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 142
Molecular simplification of natural products: Synthesis, antibacterial activity, and molecular docking studies of berberine open models 142
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 141
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 141
Lubeluzole: from anti-ischemic to chemosensitizing agent 141
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 141
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 141
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 141
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 139
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 139
Pharmacological differences between R(-) and S(+) Tocainide 138
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 138
Analoghi chirali della Tocainide: attività analgesica centrale 138
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 137
Biostimulant Formulations and Moringa oleifera Extracts to Improve Yield, Quality, and Storability of Hydroponic Lettuce 136
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 135
a-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 133
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypothesis on mechanism of action. 133
Pharmacological differences between R(-) and S(+) Tocainide 133
Synthesis of 7a-[2(2,6-dimethylphenoxy)ethyl]hexahydro-1H-pyrrolizine, bioisostere of pilsicainide 133
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 133
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 133
Targeting the pregnane X receptor using microbial metabolite mimicry 133
Structure-Based Identification and Design of Angiotensin Converting Enzyme-Inhibitory Peptides from Whey Proteins 132
Camel (Camelus spp.) Urine Bioactivity and Metabolome: A Systematic Review of Knowledge Gaps, Advances, and Directions for Future Research 132
The effects of tocainide and its chiral analogs on sodium channels of human muscle 130
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 130
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 130
Microwave-Assisted Extraction of Bioactive Compounds from Lentil Wastes: Antioxidant Activity Evaluation and Metabolomic Characterization 129
hERG stereoselective modulation by mexiletine‐derived ureas: Molecular docking study, synthesis, and biological evaluation 129
An Introduction to Medicinal Chemistry 128
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 127
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 126
Stereospecific Synthesis of p-Hydroxymexiletine and Hydroxymethylmexiletine: the two Main Metabolites of Mexiletine 126
Antiviral Properties of Moringa oleifera Leaf Extracts against Respiratory Viruses 126
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 125
2,6-Xilididi e beta-2,6-xililosietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 125
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 125
Mexiletine analogues as potent skeletal muscle sodium channel blockers: hypotheses on the interactions at the main binding sites 125
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 124
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 124
Activity of natural hydroxytyrosol versus a synthestic sample and its chiral analogues: hypothesis of mechanism of action 124
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 123
Comment on "in Situ Derivatization of (RS)-Mexiletine and Enantioseparation Using Micellar Liquid Chromatography: A Green Approach" 123
Antioxidant activity of Uva di Troia ad acino piccolo: comparison of different extraction methods 122
Analisi Farmaceutica 122
Totale 15.745
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Categoria #
all - tutte 143.509
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 143.509
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.529 0 0 0 96 48 100 71 98 115 118 308 575
2022/20233.285 541 282 170 303 429 438 31 392 521 24 84 70
2023/20241.316 94 230 52 98 67 282 35 74 35 45 149 155
2024/20255.018 167 105 449 162 129 382 389 493 260 260 694 1.528
2025/202611.953 1.458 441 1.101 1.198 1.132 709 1.460 317 1.026 1.042 428 1.641
2026/20273.490 457 599 1.261 1.173 0 0 0 0 0 0 0 0
Totale 36.205