IRIS
LENTINI, Giovanni
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 13.959
AS - Asia 5.799
EU - Europa 4.328
SA - Sud America 1.384
AF - Africa 225
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 4
Totale 25.718
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 13.761
SG - Singapore 2.494
CN - Cina 1.518
BR - Brasile 1.166
HK - Hong Kong 892
SE - Svezia 818
IT - Italia 716
RU - Federazione Russa 624
UA - Ucraina 581
DE - Germania 518
FI - Finlandia 352
VN - Vietnam 280
GB - Regno Unito 273
FR - Francia 131
IN - India 125
CI - Costa d'Avorio 112
CA - Canada 106
AR - Argentina 83
ID - Indonesia 76
TR - Turchia 70
BD - Bangladesh 59
MX - Messico 57
JP - Giappone 50
ZA - Sudafrica 45
BE - Belgio 40
IQ - Iraq 40
PL - Polonia 40
ES - Italia 38
IE - Irlanda 37
NL - Olanda 36
CO - Colombia 31
AT - Austria 29
EC - Ecuador 24
MA - Marocco 22
UY - Uruguay 22
IR - Iran 21
LT - Lituania 21
PK - Pakistan 21
SA - Arabia Saudita 20
VE - Venezuela 18
UZ - Uzbekistan 17
AU - Australia 14
PH - Filippine 14
PY - Paraguay 13
PE - Perù 12
RO - Romania 12
KR - Corea 11
EG - Egitto 10
AE - Emirati Arabi Uniti 9
CL - Cile 9
TH - Thailandia 9
CZ - Repubblica Ceca 8
KE - Kenya 8
MY - Malesia 8
TT - Trinidad e Tobago 8
OM - Oman 7
TW - Taiwan 7
IL - Israele 6
LV - Lettonia 6
PT - Portogallo 6
AZ - Azerbaigian 5
BO - Bolivia 5
BY - Bielorussia 5
CR - Costa Rica 5
DZ - Algeria 5
KG - Kirghizistan 5
NI - Nicaragua 5
NP - Nepal 5
NZ - Nuova Zelanda 5
RS - Serbia 5
SI - Slovenia 5
TN - Tunisia 5
EE - Estonia 4
EU - Europa 4
GE - Georgia 4
HU - Ungheria 4
JM - Giamaica 4
JO - Giordania 4
LB - Libano 4
PS - Palestinian Territory 4
AO - Angola 3
BB - Barbados 3
CH - Svizzera 3
DO - Repubblica Dominicana 3
KH - Cambogia 3
KW - Kuwait 3
NG - Nigeria 3
NO - Norvegia 3
SN - Senegal 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
DK - Danimarca 2
ET - Etiopia 2
HN - Honduras 2
HR - Croazia 2
MK - Macedonia 2
PA - Panama 2
AM - Armenia 1
BG - Bulgaria 1
Totale 25.700
Salva come PNG Salva come JPEG
Città #
Fairfield 1.325
Jacksonville 1.313
Ashburn 1.254
Singapore 1.235
Chandler 1.213
Woodbridge 965
Hong Kong 885
Houston 707
Nyköping 587
Dallas 577
Cambridge 529
Seattle 516
Wilmington 456
Ann Arbor 406
Beijing 362
Roxbury 298
Lawrence 292
Nanjing 292
New York 244
Los Angeles 209
Bari 205
Des Moines 192
Boardman 165
Princeton 164
Abidjan 112
Brooklyn 112
Santa Clara 100
São Paulo 94
Ho Chi Minh City 91
Munich 82
Buffalo 76
Hebei 73
San Diego 73
Shenyang 71
Nanchang 69
Inglewood 66
London 60
Jiaxing 59
Moscow 56
Helsinki 54
Hanoi 53
Jakarta 51
Chicago 47
Tokyo 45
Dearborn 44
Rio de Janeiro 44
Guangzhou 42
Brussels 39
Pune 37
Warsaw 36
Dublin 34
Changsha 33
Rome 32
San Francisco 32
Tianjin 32
Toronto 29
Turku 29
North Bergen 28
Atlanta 27
Montreal 27
Council Bluffs 26
Frankfurt am Main 25
Paris 25
Dong Ket 24
Jinan 24
Johannesburg 24
Redwood City 24
Stockholm 24
Denver 21
Dhaka 21
Brasília 20
Phoenix 20
Porto Alegre 20
Belo Horizonte 19
Chennai 19
Istanbul 19
Marseille 19
Milan 19
San Mateo 19
The Dalles 19
Columbus 18
Montevideo 18
Salvador 18
Shanghai 18
Boston 17
Wuhan 17
Falls Church 16
Leawood 16
Manchester 16
Tashkent 16
Zhengzhou 16
Amsterdam 15
Da Nang 15
Poplar 15
Ardabil 14
Curitiba 14
Haiphong 14
Hefei 14
Washington 14
Baghdad 13
Totale 17.125
Salva come PNG Salva come JPEG
Nome #
(S)-ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate 192
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods 189
A Mini-Review on Thalidomide: Chemistry, Mechanisms of Action, Therapeutic Potential and Anti-Angiogenic Properties in Multiple Myeloma 188
Acidi carbossilici derivati dell'antracene e suoi isosteri: effetti sulla conduttanza al cloro 187
Fitocomplesso polifenolico standardizzato per la prevenzione delle patologie correlate all’esposizione da sostanze reattive dell’ossigeno e relativo metodo di produzione 163
A convenient synthesis of lubeluzole and its enantiomer: Evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells 161
A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues 155
Plant-derived anticancer agents: Lessons from the pharmacology of geniposide and its aglycone, genipin 152
Preparation of (–)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs 152
2,6-xilididi e b-2,6,-xililossietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 151
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents 151
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods 150
Capillary zone electrophoresis for separation and quantitative determination of mexiletine and its main phase i metabolites 149
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca2+/calmodulin-dependent Kinase II 146
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletine 146
2-Arylazetidines as ligands for nicotinic acetylcholine receptors 141
N-(Phenoxyalkyl)amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II 140
Enzymatic Resolution of α-Methyleneparaconic Acids and Evaluation of their Biological Activity 138
Chiral aryloxyalkylamines: selective 5-HT1B/1D activation and analgesic activity 137
Positional isomers of mannose-quinoline conjugates and their copper complexes: Exploring the biological activity 137
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 137
The chemistry and pharmacology of citrus limonoids 136
Searching for new antiarrhythmic agents: evaluation of meta-hydroxymexiletine enantiomers 135
An improved synthesis of m-hydroxymexiletine, a potent mexiletine metabolite 135
Optimization of microwave-assisted extraction of antioxidants from bamboo shoots of Phyllostachys pubescens 135
Evaluating Dietary Red Lentil Screenings on Performance, Antioxidant Status, Caecal Environment, and Intestinal Morphometric Features in Rabbits 132
CONSERVATION, TAXONOMY, ECOLOGICAL DISTRIBUTION, AND POTENTIAL APPLICATION OF THE CULINARYMEDICINAL MUSHROOM LECCINUM SCABRUM 132
Hydroxylated analogs of mexiletine as tools for structural-requirements investigation of the sodium channel blocking activity 132
Recent trends in the discovery of small molecule blockers of sodium channels 130
Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use-Dependent Inhibitors of Voltage-Gated Sodium Channels 130
Le applicazioni della chimica farmaceutica 128
Old drug scaffold, new activity: Thalidomide-correlated compounds exert different effects on breast cancer cell growth and progression 128
The practice of medicinal chemistry 126
Facile entry to (-)-R- and (+)-(S)-mexiletine 126
2-(9-Antryl)alcanoic acids as chloride channel modulators 124
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 124
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues 124
The therapeutic potential of rutin for diabetes: An update 123
Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules 123
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 121
Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres 121
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition 119
Microwave-assisted synthesis of KN-93, a potent and selective inhibitor of Ca2+/calmoduline-dependent protein kinase II 118
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 118
Pharmacological differences between R(-) and S(+) Tocainide 117
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell'acido O-fenilmandelico, utile agente di solvatazione chirale 114
New doxorubicin nanocarriers based on cyclodextrins 114
Facile routes for the preparation of 3,4-disubstituted 1,3-oxazolidines and 1,2,5-trisubstituted imidazolidin-4-ones 113
Pharmacological differences between R(-) and S(+) Tocainide 112
Analisi di Horeau modificata: applicazione ad acidi alfa-arilossialcanoici ed isosteri omochirali 111
Facile Entry to Ethyl Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate: a Versatile Pharmaceutical Intermediate 111
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 111
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 110
Microwave-Assisted Extraction of Pleurotus mushrooms cultivated on wine grape pomace and antioxidant activity evaluation 109
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypotesis on mechanism of action 109
Molecular determinants of state dependent block of voltage-gated sodium channels by pilsicainide 108
The effects of tocainide and its chiral analogs on sodium channels of human muscle 107
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 107
alpha-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 107
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: hypothesis on mechanism of action. 106
Chiral mexiletine analogues as skeletal muscle voltage-gated sodium channel blocking agents 106
Applicazione di un disegno sperimentale alla sintesi enantiospecifica one-step dell’acido O-fenilmandelico, utile agente di solvatazione chirale 105
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 105
Facile, alternative route to Lubeluzole, its enantiomer, and the racemate 104
Alpha-glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 104
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
Microwave assisted synthesis of (±)-mandelic acid-d5, optical resolution, and absolute configuration determination 104
Trivial, common, and systematic chemical names 103
a-Glucosidase inhibitors: SAR studies on N-(aryloxyalkyl)phthalimides and their isosters 103
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation 103
Comment on "in Situ Derivatization of (RS)-Mexiletine and Enantioseparation Using Micellar Liquid Chromatography: A Green Approach" 103
Stereospecific synthesis and absolute configuration of Mexiletine 102
Analisi di Horeau modificata: applicazione ad acidi alpha-arilossialcanoici ed isosteri omochirali 102
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities 102
Analoghi chirali della mexiletina: blocco stereoselettivo dei canali per gli ioni sodio e ipotesi sull’interazione recettoriale 101
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 100
6) Stereochemical aspects in structure-activity relationship of heterocyclic compounds active on muscle fiber sodium channels 99
ANTIARRHYTHMIC AGENTS ENDOWED WITH ANTIOXIDANT PROPERTIES 98
Molecular Determinants of Human Voltage-Gated Sodium Channels Blockade by Lubeluzole 98
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 98
Did ebola survivors use plant medicines, and if so, which ones? 98
Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective 98
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 98
Analisi Farmaceutica 97
2,6-Xilididi e beta-2,6-xililosietilammine come ligandi anfipatici per i recettori benzodiazepinici di tipo mitocondriale 97
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents 97
Pharmacological differences between R(-) and S(+) tocainide 96
Analoghi chirali della Tocainide: attività analgesica centrale 96
Discovery of a new mexiletine-derived agonist of the hERG K+channel 96
Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs 96
Arilossialchilammine come ligandi per i recettori 5-HT1B/1D: Bioisosteria, chiralità e selettività 95
Antimyotonic effects of enantiomers of mexiletine-like drugs 95
Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs 94
Lubeluzole: from anti-ischemic to chemosensitizing agent 94
Ebola therapy: Developing new drugs or repurposing old ones? 93
Activity of natural hydroxytyrosol versus a synthetic sample and its chiral analogues: Hypothesis on mechanism of action 93
Phytochemical, Antioxidant and Anti-a-glucosidase Activity Evaluations of Bergenia cordifolia 93
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na+ channels with increased potency and improved use-dependent activity 92
Analoghi rigidi della Tocainide: 2',6'-Prolinoxilidide e suoi derivati 92
The trivial names of citrus limonoids 92
Totale 11.894
Salva come PNG Salva come JPEG
Categoria #
all - tutte 113.288
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 113.288
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.491 0 0 0 0 0 111 231 131 285 374 208 151
2021/20221.987 89 333 36 96 48 100 71 98 115 118 308 575
2022/20233.285 541 282 170 303 429 438 31 392 521 24 84 70
2023/20241.316 94 230 52 98 67 282 35 74 35 45 149 155
2024/20255.018 167 105 449 162 129 382 389 493 260 260 694 1.528
2025/20265.563 1.458 441 1.101 1.198 1.132 233 0 0 0 0 0 0
Totale 26.325