IRIS
DE LUCA, Annamaria
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 15.623
AS - Asia 5.617
EU - Europa 3.839
SA - Sud America 1.532
AF - Africa 152
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 6
AN - Antartide 1
Totale 26.784
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 15.407
SG - Singapore 2.483
CN - Cina 1.418
BR - Brasile 1.345
HK - Hong Kong 821
SE - Svezia 694
IT - Italia 566
RU - Federazione Russa 541
UA - Ucraina 509
DE - Germania 473
FI - Finlandia 314
VN - Vietnam 303
GB - Regno Unito 291
FR - Francia 142
IN - India 135
CA - Canada 123
ID - Indonesia 78
AR - Argentina 73
BD - Bangladesh 63
MX - Messico 62
CI - Costa d'Avorio 50
IQ - Iraq 50
BE - Belgio 47
NL - Olanda 47
JP - Giappone 43
IE - Irlanda 40
PL - Polonia 40
ES - Italia 37
TR - Turchia 37
ZA - Sudafrica 29
IR - Iran 28
EC - Ecuador 27
AT - Austria 23
CZ - Repubblica Ceca 20
UZ - Uzbekistan 20
MA - Marocco 19
VE - Venezuela 18
CL - Cile 17
CO - Colombia 17
PK - Pakistan 17
AE - Emirati Arabi Uniti 14
LT - Lituania 14
SA - Arabia Saudita 14
KE - Kenya 13
KR - Corea 12
AU - Australia 11
EG - Egitto 10
PY - Paraguay 10
UY - Uruguay 10
IL - Israele 9
PE - Perù 9
AZ - Azerbaigian 7
DZ - Algeria 7
JO - Giordania 7
KG - Kirghizistan 7
KZ - Kazakistan 6
RS - Serbia 6
TN - Tunisia 6
BO - Bolivia 5
EU - Europa 5
MY - Malesia 5
NP - Nepal 5
OM - Oman 5
PA - Panama 5
TT - Trinidad e Tobago 5
TW - Taiwan 5
AL - Albania 4
CR - Costa Rica 4
DK - Danimarca 4
HN - Honduras 4
NG - Nigeria 4
PH - Filippine 4
SN - Senegal 4
CH - Svizzera 3
EE - Estonia 3
JM - Giamaica 3
KH - Cambogia 3
NI - Nicaragua 3
NO - Norvegia 3
NZ - Nuova Zelanda 3
RO - Romania 3
AO - Angola 2
BH - Bahrain 2
BY - Bielorussia 2
DM - Dominica 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GE - Georgia 2
GR - Grecia 2
LB - Libano 2
LV - Lettonia 2
PS - Palestinian Territory 2
PT - Portogallo 2
QA - Qatar 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
AF - Afghanistan, Repubblica islamica di 1
AQ - Antartide 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
Totale 26.765
Salva come PNG Salva come JPEG
Città #
Ashburn 1.659
Fairfield 1.626
Woodbridge 1.335
Singapore 1.276
Chandler 1.245
Jacksonville 1.127
Houston 935
Hong Kong 818
Cambridge 682
Seattle 643
Dallas 624
Wilmington 569
Ann Arbor 550
Nyköping 512
Beijing 371
Lawrence 274
Roxbury 272
Nanjing 254
Los Angeles 195
New York 194
Des Moines 177
Princeton 171
Boardman 168
Bari 161
Inglewood 119
São Paulo 106
Ho Chi Minh City 105
San Diego 97
Nanchang 78
Santa Clara 78
Hebei 70
Hanoi 67
Buffalo 64
Jiaxing 62
Munich 62
Chicago 58
Jakarta 58
London 55
Brooklyn 54
Shenyang 49
Abidjan 48
Brussels 45
Tianjin 41
Helsinki 40
Bitetto 38
Dublin 37
Council Bluffs 36
Rio de Janeiro 36
Changsha 35
Pune 35
Milan 34
Dearborn 33
Dong Ket 33
Warsaw 33
Brasília 32
Belo Horizonte 30
Nuremberg 30
Bitonto 29
Toronto 29
San Francisco 28
Shanghai 28
Tokyo 27
Victoria 27
San Mateo 26
The Dalles 26
Turku 26
Chennai 25
Frankfurt am Main 25
Guangzhou 25
Stockholm 25
Columbus 24
Montreal 24
Moscow 24
Baghdad 23
Mexico City 23
Falls Church 22
Denver 21
Leawood 21
Zhengzhou 21
Phoenix 20
Ardabil 19
Augusta 19
Curitiba 19
Orem 19
Paris 19
Redwood City 19
Taranto 19
Tashkent 19
Brno 18
Campinas 18
Wuhan 18
Atlanta 17
Boston 17
Falkenstein 16
Monmouth Junction 16
Ottawa 16
Grottaglie 15
Hefei 15
Jinan 15
Poplar 15
Totale 18.553
Salva come PNG Salva come JPEG
Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 440
Proof-of-concept validation of the mechanism of action of Src tyrosine kinase inhibitors in dystrophic mdx mouse muscle: in vivo and in vitro studies 259
Myasthenia Gravis Treatment: From Old Drugs to Innovative Therapies with a Glimpse into the Future 217
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 209
Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of Duchenne muscular dystrophy: a comparison with the gold standard, α-methyl prednisolone. 200
Contractile efficiency of dystrophic mdx mouse muscle: In vivo and ex vivo assessment of adaptation to exercise of functional end points 191
Isolation and characterization of neural stem cells from dystrophic mdx mouse 191
Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy 189
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options 183
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice 179
Dasatinib/HP-β-CD inclusion complex based aqueous formulation as a promising tool for the treatment of paediatric neuromuscular disorders 173
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 170
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 163
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 163
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy. 162
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 159
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 155
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 153
Risk of myopathy in patients in therapy with statins: Identification of biological markers in a pilot study 146
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 142
Aging and chloride channel regulation in rat fast-twitch muscle fibres 141
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 140
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 139
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 138
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 137
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 137
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 135
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 134
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 133
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 131
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 128
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 126
Ergogenic effect of bcaas and l-alanine supplementation: Proof-of-concept study in a murine model of physiological exercise 126
Changes of chloride channel regulation in rat skeletal muscle during aging 125
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 125
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 125
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 124
Aberrant mechanical-metabolic coupling in muscular dystrophy: gene expression and functional studies in mdx mouse muscle in relation to age and exercise 124
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 124
Proteome analysis in dystrophic mdx mouse muscle reveals a drastic alteration of key metabolic and contractile proteins after chronic exercise and the potential modulation by anti-oxidant compounds 123
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 122
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 122
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 121
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 120
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 119
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 115
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 115
Mechanisms of block of sodium channels in human myoballs by local anaesthetics with different use dependence 114
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 114
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 114
GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy 114
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 113
First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant 113
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 113
Taurine and skeletal muscle ion channels 112
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 112
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 111
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 111
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading 111
Erratum: Corrigendum to “Isolation and characterization of neural stem cells from dystrophic mdx mouse” (Experimental Cell Research (2016) 343(1) (190–207) (S0014482716300593) (10.1016/j.yexcr.2016.03.019)) 110
227thENMC International Workshop:. Finalizing a plan to guarantee quality in translational research for neuromuscular diseases Heemskerk, Netherlands, 10-11 February 2017 110
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 109
Age-dependent modification of phosphorylation state of skeletal muscle chloride channel controls its biophysical and pharmacological properties 109
The different use dependences of tocainide and benzocaine are correlated with different effects on sodium channel inactivation 109
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 109
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 109
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 109
Stakeholder cooperation to overcome challenges in orphan medicine development: The example of Duchenne muscular dystrophy 109
Muscle loading modulates aquaporin-4 expression in skeletal muscle 108
The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo 108
Update on Standard Operating Procedures in Preclinical Research for DMD and SMA Report of TREAT-NMD Alliance Workshop, Schiphol Airport, 26 April 2015, the Netherlands 108
Prednisone in dystrophin-deficient Caernorabditis elegans 107
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle 107
Cisplatin-Induced Skeletal Muscle Dysfunction: Mechanisms and Counteracting Therapeutic Strategies 106
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 105
Ultrasonography validation for early alteration of diaphragm echodensity and function in the mdx mouse model of Duchenne muscular dystrophy 105
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 104
Stereospecific Synthesis of ‘‘para-Hydroxymexiletine’’ and Sodium Channel Blocking Activity Evaluation 104
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 104
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 104
Effects of prednisolone on the dystrophin-associated proteins in the blood-brain barrier and skeletal muscle of dystrophic mdx mice. 103
Measuring clinical effectiveness of medicinal products for the treatment of Duchenne muscular dystrophy. 102
Evaluation of potential synergistic action of a combined treatment with alpha-methyl-prednisolone and taurine on the mdx mouse model of Duchenne muscular dystrophy. 102
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 102
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 102
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1.4 channels 101
Developmental changes of membrane electrical properties of rat skeletal muscle fibers produced by prenatal exposure to carbon monoxide 101
Antitumorali 101
Safety issues and harmful pharmacological interactions of nutritional supplements in Duchenne muscular dystrophy: considerations for Standard of Care and emerging virus outbreaks 101
"The Social Network" and Muscular Dystrophies: The Lesson Learnt about the Niche Environment as a Target for Therapeutic Strategies 101
A decade of optimizing drug development for rare neuromuscular disorders through TACT 99
β‐Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation 99
Drug screening for muscular dystrophy: From target to function toward patients, is anything lost? 98
A new original compound, which inhibits calpain 1-2 and reactive oxygen species, reduces the dystrophic progression of mdx mice 98
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide 98
Taurine and skeletal muscle disorders 98
Pharmacology of CLC chloride channels and transporters 98
Skeletal Muscle Chloride Channel, a Biophysical Sensor of Dystrophic Progression in Mdx Mouse, is a Potential Target of Pro-inflammatory Mediators 97
Nerve growth factor and its receptors TrkA and p75 are upregulated in the brain of mdx dystrophic mouse 97
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 97
Totale 12.893
Salva come PNG Salva come JPEG
Categoria #
all - tutte 120.225
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 120.225
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.603 0 0 0 0 0 104 203 153 271 422 287 163
2021/20221.994 70 285 22 114 85 116 105 113 120 137 310 517
2022/20233.187 494 268 199 307 393 441 21 343 533 30 87 71
2023/20241.430 89 231 49 83 98 224 158 295 16 55 22 110
2024/20254.954 144 70 388 154 130 460 468 492 225 259 729 1.435
2025/20265.535 1.485 462 1.035 1.022 1.102 429 0 0 0 0 0 0
Totale 27.408