IRIS
DE LUCA, Annamaria
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 20.464
AS - Asia 7.168
EU - Europa 6.032
SA - Sud America 1.961
Continente sconosciuto - Info sul continente non disponibili 668
AF - Africa 275
OC - Oceania 20
AN - Antartide 1
Totale 36.589
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 20.045
SG - Singapore 3.079
IT - Italia 2.138
CN - Cina 1.594
BR - Brasile 1.568
HK - Hong Kong 902
SE - Svezia 698
RU - Federazione Russa 557
DE - Germania 534
UA - Ucraina 518
FR - Francia 431
FI - Finlandia 412
VN - Vietnam 391
GB - Regno Unito 336
IN - India 235
BD - Bangladesh 227
CA - Canada 226
AR - Argentina 128
ID - Indonesia 110
IQ - Iraq 97
MX - Messico 80
TR - Turchia 76
CO - Colombia 66
NL - Olanda 64
ZA - Sudafrica 62
JP - Giappone 61
EC - Ecuador 57
CI - Costa d'Avorio 53
ES - Italia 51
BE - Belgio 49
IE - Irlanda 49
PK - Pakistan 49
PL - Polonia 44
VE - Venezuela 41
CL - Cile 40
SA - Arabia Saudita 40
MA - Marocco 36
UZ - Uzbekistan 34
IR - Iran 29
AT - Austria 27
MY - Malesia 26
EG - Egitto 24
PH - Filippine 23
AE - Emirati Arabi Uniti 22
HN - Honduras 22
KE - Kenya 21
CR - Costa Rica 20
CZ - Repubblica Ceca 20
JO - Giordania 19
UY - Uruguay 19
IL - Israele 18
TN - Tunisia 18
AU - Australia 17
DZ - Algeria 16
NP - Nepal 16
PE - Perù 16
LT - Lituania 15
PY - Paraguay 15
TT - Trinidad e Tobago 15
KR - Corea 13
JM - Giamaica 12
KZ - Kazakistan 12
AZ - Azerbaigian 10
BO - Bolivia 10
ET - Etiopia 10
NI - Nicaragua 10
TH - Thailandia 10
KG - Kirghizistan 9
RS - Serbia 9
SV - El Salvador 9
TW - Taiwan 9
AL - Albania 8
OM - Oman 8
PS - Palestinian Territory 8
RO - Romania 8
DK - Danimarca 7
EE - Estonia 7
GE - Georgia 7
HU - Ungheria 7
LB - Libano 7
PA - Panama 7
AO - Angola 6
CH - Svizzera 6
GR - Grecia 6
GT - Guatemala 6
PT - Portogallo 6
SC - Seychelles 6
EU - Europa 5
KH - Cambogia 4
NG - Nigeria 4
NO - Norvegia 4
SN - Senegal 4
BY - Bielorussia 3
GP - Guadalupe 3
HR - Croazia 3
KW - Kuwait 3
LV - Lettonia 3
LY - Libia 3
ME - Montenegro 3
NZ - Nuova Zelanda 3
Totale 35.874
Salva come PNG Salva come JPEG
Città #
Ashburn 2.460
Singapore 1.676
Fairfield 1.626
San Jose 1.387
Woodbridge 1.335
Chandler 1.245
Jacksonville 1.133
Houston 942
Hong Kong 893
Milan 745
Cambridge 684
Dallas 654
Seattle 647
Wilmington 573
Ann Arbor 553
Nyköping 512
Council Bluffs 470
Beijing 415
Lawrence 275
New York 273
Bari 272
Roxbury 272
Lauterbourg 266
Nanjing 255
Los Angeles 248
Rome 239
Boardman 184
Des Moines 179
Santa Clara 174
Princeton 173
São Paulo 162
Helsinki 138
Ho Chi Minh City 128
Inglewood 119
San Diego 101
Columbus 96
Hanoi 91
Buffalo 79
Nanchang 79
Chicago 76
Hebei 70
Toronto 64
Jiaxing 62
Munich 62
Jakarta 61
Brooklyn 59
London 59
Abidjan 51
Shenyang 49
Brussels 46
Baghdad 45
Frankfurt am Main 45
Turin 45
Figino 44
Dublin 42
San Francisco 42
Rio de Janeiro 41
Tianjin 41
Tokyo 40
Bitetto 38
Brasília 38
Montreal 38
Washington 38
Phoenix 37
Falkenstein 36
Pune 36
Changsha 35
Dearborn 35
Nuremberg 34
Warsaw 34
Chennai 33
Dong Ket 33
Belo Horizonte 32
The Dalles 32
Orem 31
Shanghai 31
Tashkent 31
Bitonto 30
Mexico City 30
Taranto 30
Atlanta 29
Denver 29
Victoria 29
San Mateo 27
Stockholm 27
Turku 26
Guangzhou 25
Moscow 25
Naples 25
North Bergen 25
Johannesburg 23
Medellín 23
Paris 23
Boston 22
Curitiba 22
Falls Church 22
Leawood 21
Zhengzhou 21
Augusta 20
Bologna 20
Totale 23.993
Salva come PNG Salva come JPEG
Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 473
Myasthenia Gravis Treatment: From Old Drugs to Innovative Therapies with a Glimpse into the Future 381
Proof-of-concept validation of the mechanism of action of Src tyrosine kinase inhibitors in dystrophic mdx mouse muscle: in vivo and in vitro studies 301
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice 262
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 256
Contractile efficiency of dystrophic mdx mouse muscle: In vivo and ex vivo assessment of adaptation to exercise of functional end points 252
Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of Duchenne muscular dystrophy: a comparison with the gold standard, α-methyl prednisolone. 249
Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy 243
Isolation and characterization of neural stem cells from dystrophic mdx mouse 221
Dasatinib/HP-β-CD inclusion complex based aqueous formulation as a promising tool for the treatment of paediatric neuromuscular disorders 221
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 218
GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy 210
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 208
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 207
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options 207
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy. 203
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 191
A new benzylated proline-like tocainide derivative is a potent use dependent skeletal muscle Na+ channel blocker with a potential antimyotonic activity 184
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents 184
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 174
Risk of myopathy in patients in therapy with statins: Identification of biological markers in a pilot study 172
Blockade by cAMP of native sodium channels of adult rat skeletal muscle fibers 171
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading 170
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 169
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na+ channels enhancing the antimyotonic activity in vivo 169
Ergogenic effect of bcaas and l-alanine supplementation: Proof-of-concept study in a murine model of physiological exercise 168
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 167
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 167
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 166
Aging and chloride channel regulation in rat fast-twitch muscle fibres 165
A new benzylated proline-like tocainide derivative is a potent use-dependent skeletal muscle Na+ channel blocker with a potential anti-myotonic activity 164
Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid 164
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 161
Aberrant mechanical-metabolic coupling in muscular dystrophy: gene expression and functional studies in mdx mouse muscle in relation to age and exercise 160
Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers 159
Alteration of stim1/orai1-mediated soce in skeletal muscle: Impact in genetic muscle diseases and beyond 159
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 158
Stakeholder cooperation to overcome challenges in orphan medicine development: The example of Duchenne muscular dystrophy 157
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 153
Effect of rat hindlimb suspension on cable properties, ionic conductances and fiber type composition of slow-twitch muscle. 152
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 152
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 151
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle 150
227thENMC International Workshop:. Finalizing a plan to guarantee quality in translational research for neuromuscular diseases Heemskerk, Netherlands, 10-11 February 2017 150
Changes of chloride channel regulation in rat skeletal muscle during aging 149
Cisplatin-Induced Skeletal Muscle Dysfunction: Mechanisms and Counteracting Therapeutic Strategies 149
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 148
"The Social Network" and Muscular Dystrophies: The Lesson Learnt about the Niche Environment as a Target for Therapeutic Strategies 148
Ultrasonography validation for early alteration of diaphragm echodensity and function in the mdx mouse model of Duchenne muscular dystrophy 148
Effetti di una nuova 1-4 diidropiridina, il Bay K 8644, su organi a muscolatura liscia isolati di cavia 147
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 146
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 146
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 146
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 145
Proteome analysis in dystrophic mdx mouse muscle reveals a drastic alteration of key metabolic and contractile proteins after chronic exercise and the potential modulation by anti-oxidant compounds 145
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 144
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 143
First evaluation of the potential effectiveness in muscular dystrophy of a novel chimeric compound, BN 82270, acting as calpain-inhibitor and anti-oxidant 143
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 142
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 142
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 142
LKB1 signaling is altered in skeletal muscle of a Duchenne muscular dystrophy mouse model 141
Age-dependent modification of phosphorylation state of skeletal muscle chloride channel controls its biophysical and pharmacological properties 141
(2) Save to: more options Isosteric derivates of mexiletine: New potent use-dependent blockers of skeletal muscle sodium channels with potential antimyotonic activity 141
Searching for novel anti-myotonic agents: Pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide 137
A new original compound, which inhibits calpain 1-2 and reactive oxygen species, reduces the dystrophic progression of mdx mice 136
"Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic 136
Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy 135
Excitation-contraction coupling of extensor digitorum longus muscle of dystrophic MDX mouse 135
β‐Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation 135
The different use dependences of tocainide and benzocaine are correlated with different effects on sodium channel inactivation 134
Chloride conductance is oppositely affected in extensorum digitorum longus and diaphragm muscles from mdx mice 134
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 134
Update on Standard Operating Procedures in Preclinical Research for DMD and SMA Report of TREAT-NMD Alliance Workshop, Schiphol Airport, 26 April 2015, the Netherlands 134
A decade of optimizing drug development for rare neuromuscular disorders through TACT 134
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy 133
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 132
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 132
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 132
A novel kcna2 variant in a patient with non-progressive congenital ataxia and epilepsy: Functional characterization and sensitivity to 4-aminopyridine 132
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 131
Prednisone in dystrophin-deficient Caernorabditis elegans 130
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 129
Antitumorali 129
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids 128
Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy 127
Mechanisms of block of sodium channels in human myoballs by local anaesthetics with different use dependence 127
The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo 127
Erratum: Corrigendum to “Isolation and characterization of neural stem cells from dystrophic mdx mouse” (Experimental Cell Research (2016) 343(1) (190–207) (S0014482716300593) (10.1016/j.yexcr.2016.03.019)) 127
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 127
Effects of taurine analogues on chloride channel conductance of rat skeletal muscle fibers: a structure-activity relationship investigation 126
Muscle loading modulates aquaporin-4 expression in skeletal muscle 125
Gentamicin treatment in exercised mdx mice: Identification of dystrophin-sensitive pathways and evaluation of efficacy in work-loaded dystrophic muscle 125
Alterazioni delle proprietà biofisiche dei canali al K+ del muscolo scheletrico di ratto prodotte dall'esposizione prenatale a monossido di carbonio 124
Taurine and skeletal muscle disorders 124
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels 124
Circadian Genes as Exploratory Biomarkers in DMD: Results From Both the mdx Mouse Model and Patients 124
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 123
Molecular determinants of 2(p-chlorophenoxy)propionic acid for modulation of the native chloride channel conductance of rat skeletal muscle 123
Branched-Chain Amino Acids and Di-Alanine Supplementation in Aged Mice: A Translational Study on Sarcopenia 122
Totale 16.282
Salva come PNG Salva come JPEG
Categoria #
all - tutte 149.294
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 149.294
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.617 0 0 0 114 85 116 105 113 120 137 310 517
2022/20233.187 494 268 199 307 393 441 21 343 533 30 87 71
2023/20241.430 89 231 49 83 98 224 158 295 16 55 22 110
2024/20254.954 144 70 388 154 130 460 468 492 225 259 729 1.435
2025/202611.214 1.485 462 1.035 1.022 1.102 540 1.417 338 1.067 1.042 367 1.337
2026/20273.502 482 623 973 1.424 0 0 0 0 0 0 0 0
Totale 36.589