IRIS
PIERNO, Sabata
 Distribuzione geografica
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Continente #
NA - Nord America 9.354
AS - Asia 3.032
EU - Europa 2.542
SA - Sud America 762
Continente sconosciuto - Info sul continente non disponibili 341
AF - Africa 128
OC - Oceania 9
Totale 16.168
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Nazione #
US - Stati Uniti d'America 9.100
SG - Singapore 1.295
IT - Italia 835
CN - Cina 711
BR - Brasile 613
HK - Hong Kong 359
SE - Svezia 351
RU - Federazione Russa 265
DE - Germania 204
UA - Ucraina 199
FR - Francia 187
FI - Finlandia 164
VN - Vietnam 164
GB - Regno Unito 157
IN - India 107
BD - Bangladesh 99
CA - Canada 97
ID - Indonesia 52
AR - Argentina 47
MX - Messico 36
NL - Olanda 28
ZA - Sudafrica 28
BE - Belgio 25
TR - Turchia 25
EC - Ecuador 24
CO - Colombia 22
IL - Israele 22
IQ - Iraq 22
PL - Polonia 22
CI - Costa d'Avorio 21
JP - Giappone 21
CR - Costa Rica 20
ES - Italia 19
GT - Guatemala 19
PK - Pakistan 19
CL - Cile 18
VE - Venezuela 17
IE - Irlanda 16
LT - Lituania 16
NI - Nicaragua 15
UZ - Uzbekistan 15
KE - Kenya 14
MA - Marocco 14
SA - Arabia Saudita 14
SV - El Salvador 14
PH - Filippine 13
HN - Honduras 12
MY - Malesia 12
SC - Seychelles 11
TN - Tunisia 11
TT - Trinidad e Tobago 11
AT - Austria 10
CZ - Repubblica Ceca 10
GP - Guadalupe 10
IR - Iran 10
KR - Corea 10
PY - Paraguay 8
AU - Australia 7
KZ - Kazakistan 7
NP - Nepal 7
PR - Porto Rico 7
JO - Giordania 6
KG - Kirghizistan 6
PE - Perù 6
AL - Albania 5
EG - Egitto 5
PS - Palestinian Territory 5
UY - Uruguay 5
AE - Emirati Arabi Uniti 4
CW - ???statistics.table.value.countryCode.CW??? 4
ET - Etiopia 4
JM - Giamaica 4
OM - Oman 4
PA - Panama 4
AO - Angola 3
DK - Danimarca 3
DZ - Algeria 3
HR - Croazia 3
NG - Nigeria 3
NO - Norvegia 3
TH - Thailandia 3
TW - Taiwan 3
AM - Armenia 2
AZ - Azerbaigian 2
BN - Brunei Darussalam 2
BO - Bolivia 2
BY - Bielorussia 2
EU - Europa 2
GR - Grecia 2
HU - Ungheria 2
KH - Cambogia 2
LY - Libia 2
NZ - Nuova Zelanda 2
RO - Romania 2
RS - Serbia 2
SN - Senegal 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BH - Bahrain 1
Totale 15.806
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Città #
Ashburn 1.256
Fairfield 841
Singapore 715
Woodbridge 608
San Jose 549
Chandler 536
Jacksonville 437
Houston 401
Hong Kong 358
Seattle 334
Milan 322
Cambridge 310
Dallas 304
Nyköping 284
Ann Arbor 278
Wilmington 258
Beijing 195
Council Bluffs 177
Nanjing 116
Los Angeles 112
Lawrence 110
Roxbury 110
Lauterbourg 107
Bari 106
New York 99
Rome 99
Princeton 92
Santa Clara 78
Boardman 76
Inglewood 67
Des Moines 65
São Paulo 59
Helsinki 49
Ho Chi Minh City 49
Hanoi 42
San Diego 37
Chicago 35
Buffalo 34
Columbus 34
Jakarta 34
Brooklyn 30
Nanchang 30
Hebei 29
Jiaxing 29
London 29
Toronto 29
Munich 27
Dong Ket 26
The Dalles 25
Brussels 24
Pune 24
Figino 23
Shenyang 22
Turin 21
Phoenix 20
San Francisco 20
Abidjan 19
Atlanta 19
Frankfurt am Main 19
Denver 17
Mexico City 17
Rio de Janeiro 17
Brasília 16
Falls Church 16
Guangzhou 16
Tokyo 16
Warsaw 16
San José 15
Turku 15
Belo Horizonte 14
Changsha 14
Dublin 14
Falkenstein 14
Guatemala City 14
Managua 14
Montreal 14
Moscow 14
San Mateo 14
Shanghai 14
Chennai 13
Manchester 13
Orem 13
San Salvador 13
Zhengzhou 13
Charlotte 12
Monmouth Junction 12
Tashkent 12
Washington 12
Boston 11
Dearborn 11
Miami 11
North Bergen 11
Redwood City 11
Augusta 10
Baghdad 10
Brno 10
Johannesburg 10
Leawood 10
Nairobi 10
Stockholm 10
Totale 10.777
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 475
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice 268
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 258
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 222
Cardiovascular, neurological, and pulmonary events following vaccination with the BNT162b2, ChAdOx1 nCoV-19, and Ad26.COV2.S vaccines: An analysis of European data 219
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 216
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 212
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 211
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 211
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options 210
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy. 204
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 195
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 178
Risk of myopathy in patients in therapy with statins: Identification of biological markers in a pilot study 174
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading 173
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 172
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 171
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 170
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 169
Aging and chloride channel regulation in rat fast-twitch muscle fibres 169
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 167
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 165
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 160
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 160
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 155
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 154
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 153
Changes of chloride channel regulation in rat skeletal muscle during aging 151
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 149
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders 149
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 148
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 148
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 148
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 148
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 146
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 146
Statin‐induced myopathy: Translational studies from preclinical to clinical evidence 146
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 145
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 145
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 143
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 143
Redox homeostasis, oxidative stress and disuse muscle atrophy 141
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 139
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 135
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 135
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 134
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 134
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 133
The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo 131
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 130
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 128
Muscle loading modulates aquaporin-4 expression in skeletal muscle 127
Effects of taurine analogues on chloride channel conductance of rat skeletal muscle fibers: a structure-activity relationship investigation 127
Taurine and skeletal muscle disorders 125
Molecular determinants of 2(p-chlorophenoxy)propionic acid for modulation of the native chloride channel conductance of rat skeletal muscle 124
Effects of Pleiotrophin Overexpression on Mouse Skeletal Muscles in Normal Loading and in Actual and Simulated Microgravity 124
Taurine and skeletal muscle ion channels 123
An olive oil-derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function 120
Block of renal CLC-K channels by phenoxy-alkyl derivatives of clofibric acid 118
Developmental changes of membrane electrical properties of rat skeletal muscle fibers produced by prenatal exposure to carbon monoxide 118
Therapeutic Targets in Amyotrophic Lateral Sclerosis: Focus on Ion Channels and Skeletal Muscle 117
Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle 116
Experimental evaluation of the effects of pravastatin on electrophysiological parameters of rat skeletal muscle 115
Comparison of excitability parameters and sodium channel behavior of fast- and slow-twitch rat skeletal muscles for the study of the effects of hindlimb suspension, a model of hypogravity. 114
Protein Kinase C-Theta Controls the CLC-1 Chloride Channel Function and Skeletal Muscle Phenotype: A Biophysical and Gene Expression Study in Pkc-Theta Null Mice 114
EFFECTS OF TAURINE DEPLETION ON MEMBRANE ELECTIRCL PROPERTIES OF RAT SKELETAL MUSCLE. 114
Dual effects of taurine on membrane ionic conductances of rat skeletal muscle fibers 113
Growth hormone secretagogues exert differential effects on skeletal muscle calcium homeostasis in male rats depending on the peptidyl/non-peptidyl structure 113
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers 112
Potential targets for skeletal muscle impairment by hypogravity: basic characterization of resting ionic conductances and mechanical threshold of rat fast- and slow-twitch muscle fibers 112
Effects of chronic growth hormone treatment in aged rats on the biophysical and pharmacological properties of skeletal muscle chloride channels 110
VARIOUS MEMBERS OF CLC FAMILY ARE DIFFERENTLY AFFECTED BY NEWLY SYNTHESIZED CLOFIBRIC ACID DERIVATIVES. 110
An olive oil–derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function 110
Molecular determinants in mexiletine and tocainide structure to improve therapy of myotonia 109
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance 109
Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat 107
Therapeutic approaches to ion channel diseases 107
Therapeutic approaches to ion channel diseases 106
Taurine and skeletal muscle ion channels 106
Hypertriglyceridemia Therapy: Past, Present and Future Perspectives 105
Different ability of clenbuterol and salbutamol to block sodium channels predicts their therapeutic use in muscle excitability disorders 105
Effects of chronic taurine treatment on the electrical and contractile properties of skeletal muscle fibers of aged rats 104
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 104
Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse 103
Potential risk of myopathy by HMG-CoA reductase inhibitors: a comparison of pravastatin and simvastatin effects on membrane electrical properties of rat skeletal muscle fibers 101
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Modification of resting chloride conductance during and after recovery from hindlimb unloading 99
Skeletal muscle disuse fiber type-dependent enhancement of Na+ channel expression 99
Molecular mechanisms responsible for fluvastatin and fenofibrateinduced reduction of resting membrane chloride conductance in rat skeletal muscle 99
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid 98
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels 97
Preclinical study of the antimyotonic efficacy of safinamide in the myotonic mouse model 97
Cyclic amidine analogs of taurine and homotaurine: synthesis and effects on rat skeletal muscle 95
Partial recovery of skeletal muscle sodium channel properties in aged rats chronically treated with growth hormone or the GH-secretagogue hexarelin 94
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Metabolic Pathways and Ion Channels Involved in Skeletal Muscle Atrophy: A Starting Point for Potential Therapeutic Strategies 91
Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle 91
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 91
Higher content of insulin-like growth factor-1 in dystrophic mdx mouse: potential role in the spontaneous regeneration through an electrophysiological investigation of muscle function 90
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Totale 14.052
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Categoria #
all - tutte 65.822
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 65.822
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022661 0 0 0 0 49 48 53 36 83 54 142 196
2022/20231.392 218 138 106 121 167 201 5 151 201 6 44 34
2023/2024805 35 94 19 41 41 86 147 275 3 11 6 47
2024/20252.072 78 35 147 71 64 189 193 199 90 106 288 612
2025/20264.633 610 224 445 381 445 225 575 152 456 410 133 577
2026/20271.558 142 191 286 846 93 0 0 0 0 0 0 0
Totale 16.168