IRIS
PIERNO, Sabata
 Distribuzione geografica
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Continente #
NA - Nord America 6.093
EU - Europa 1.133
AS - Asia 632
OC - Oceania 5
SA - Sud America 4
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 2
Totale 7.871
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Nazione #
US - Stati Uniti d'America 6.082
CN - Cina 436
SE - Svezia 341
IT - Italia 197
UA - Ucraina 189
DE - Germania 124
FI - Finlandia 112
SG - Singapore 109
GB - Regno Unito 90
IN - India 34
FR - Francia 31
VN - Vietnam 27
BE - Belgio 17
IE - Irlanda 13
CA - Canada 11
CZ - Repubblica Ceca 10
IR - Iran 9
JP - Giappone 4
AU - Australia 3
CL - Cile 3
HK - Hong Kong 3
RU - Federazione Russa 3
TR - Turchia 3
EU - Europa 2
KR - Corea 2
MA - Marocco 2
NL - Olanda 2
NZ - Nuova Zelanda 2
AT - Austria 1
DK - Danimarca 1
EE - Estonia 1
ID - Indonesia 1
LA - Repubblica Popolare Democratica del Laos 1
NO - Norvegia 1
PH - Filippine 1
QA - Qatar 1
TH - Thailandia 1
VE - Venezuela 1
Totale 7.871
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Città #
Fairfield 841
Ashburn 753
Woodbridge 607
Chandler 536
Jacksonville 434
Houston 394
Seattle 330
Cambridge 310
Nyköping 284
Ann Arbor 278
Wilmington 255
Nanjing 114
Lawrence 110
Roxbury 110
Princeton 91
Bari 90
Singapore 86
Beijing 71
Inglewood 67
Boardman 63
Des Moines 63
New York 40
San Diego 37
Los Angeles 32
Nanchang 30
Hebei 29
Jiaxing 29
Dong Ket 26
Shenyang 22
Pune 21
Brussels 17
London 16
Falls Church 15
San Mateo 14
Dublin 13
Zhengzhou 13
Changsha 12
Guangzhou 12
Helsinki 12
Monmouth Junction 12
Santa Clara 12
Shanghai 12
Dearborn 11
Redwood City 11
Brno 10
Leawood 10
Tianjin 10
Ardabil 9
Augusta 9
Brooklyn 9
Wuhan 9
Genova 8
Ningbo 8
Hefei 7
Toronto 7
Jinan 6
Norwalk 6
Indiana 5
Kilburn 5
Paris 5
Campobello Di Mazara 4
Islington 4
Jinhua 4
Montignoso 4
Munich 4
Ottawa 4
Sennori 4
Taranto 4
Trani 4
Chicago 3
Chiswick 3
Fuzhou 3
Kunming 3
New Bedfont 3
Phoenix 3
Prescot 3
San Francisco 3
Santa Marinella 3
Washington 3
Wuxi 3
Altamura 2
Bollate 2
East Stroudsburg 2
Grafing 2
Haikou 2
Hong Kong 2
Hounslow 2
Ksar el Kbir 2
Lanzhou 2
Marseille 2
Mcallen 2
Melbourne 2
Milan 2
Naples 2
Padova 2
San Marzano Di San Giuseppe 2
Santiago 2
Simi Valley 2
Tappahannock 2
Tokyo 2
Totale 6.567
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Nome #
EFFECTS OF TAURINE DEPLETION ON EXCITATION-CONTRACTION COUPLING AND CL- CONDUCTANCES OF RAT SKELETAL MUSCLE. 413
Effects of Nandrolone in the counteraction of skeletal muscle atrophy in a mouse model of muscle disuse: molecular biology and functional evaluation 138
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin 124
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles 119
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options 114
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 113
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy. 112
The biophysical and pharmacological characteristics of skeletal muscle ATP-Sensitive K+ channels are modified in K+-depleted rat, an animal model of hypokalemic periodic paralysis 108
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia 108
Risk of myopathy in patients in therapy with statins: Identification of biological markers in a pilot study 106
Electrical properties of diaphragm and EDL muscles during the life of dystrophic mice 104
Effect of taurine on excitation-contraction coupling of extensor digitorum longus muscle of dystrophic mdx mouse 103
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity 103
Redox homeostasis, oxidative stress and disuse muscle atrophy 102
Effects of clofibric acid analogs on chloride channel conductance of rat skeletal muscle 100
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice 100
Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1 99
null 99
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb unloaded mice 98
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile 96
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives 94
Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy 94
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness 93
Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats 92
null 92
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse 91
null 90
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone 90
Alteration of excitation-contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine 90
Taurine and skeletal muscle ion channels 88
The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo 88
null 86
Changes of chloride channel regulation in rat skeletal muscle during aging 85
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels 84
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice 83
Taurine: the appeal of a safe amino acid for skeletal muscle disorders. 82
Muscle loading modulates aquaporin-4 expression in skeletal muscle 80
Aging and chloride channel regulation in rat fast-twitch muscle fibres 80
Developmental changes of membrane electrical properties of rat skeletal muscle fibers produced by prenatal exposure to carbon monoxide 79
Aging-associated down-regulation of CLC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance 78
A multidisciplinary evaluation of the effectiveness of cyclosporine A in dystrophic mdx mice 78
Therapeutic approaches to genetic ion channelopathies and perspectives in drug discovery 76
Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle 76
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse 75
Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1 74
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids 72
Taurine and skeletal muscle disorders 72
Effects of chronic growth hormone treatment in aged rats on the biophysical and pharmacological properties of skeletal muscle chloride channels 70
Effects of taurine analogues on chloride channel conductance of rat skeletal muscle fibers: a structure-activity relationship investigation 70
Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice 70
Effects of chronic taurine treatment on the electrical and contractile properties of skeletal muscle fibers of aged rats 69
Dual effects of taurine on membrane ionic conductances of rat skeletal muscle fibers 69
null 69
null 68
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 68
Dual action of mexiletine and its pyrroline derivatives as skeletal muscle sodium channel blockers and anti-oxidant compounds: Toward novel therapeutic potential 68
Experimental evaluation of the effects of pravastatin on electrophysiological parameters of rat skeletal muscle 67
Effect of HMG-CoA reductase inhibitors on excitation-contraction coupling of rat skeletal muscle 66
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers 65
Protein Kinase C-Theta Controls the CLC-1 Chloride Channel Function and Skeletal Muscle Phenotype: A Biophysical and Gene Expression Study in Pkc-Theta Null Mice 64
Potential targets for skeletal muscle impairment by hypogravity: basic characterization of resting ionic conductances and mechanical threshold of rat fast- and slow-twitch muscle fibers 64
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by different impairing ClC-1 channel regulation and expression 64
Therapeutic approaches to ion channel diseases 64
Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation 64
Different ability of clenbuterol and salbutamol to block sodium channels predicts their therapeutic use in muscle excitability disorders 62
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo 62
Therapeutic approaches to ion channel diseases 61
Chronic administration of taurine to aged rats improves the electrical and contractile properties of skeletal muscle fibers 61
Growth hormone secretagogues exert differential effects on skeletal muscle calcium homeostasis in male rats depending on the peptidyl/non-peptidyl structure 61
Comparison of excitability parameters and sodium channel behavior of fast- and slow-twitch rat skeletal muscles for the study of the effects of hindlimb suspension, a model of hypogravity. 59
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance 59
Molecular determinants of 2(p-chlorophenoxy)propionic acid for modulation of the native chloride channel conductance of rat skeletal muscle 57
null 57
Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle 56
Taurine and skeletal muscle ion channels 56
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats cytofluorimetric and gene expression analysis 55
Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat 54
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid 54
Molecular determinants in mexiletine and tocainide structure to improve therapy of myotonia 53
Higher content of insulin-like growth factor-1 in dystrophic mdx mouse: potential role in the spontaneous regeneration through an electrophysiological investigation of muscle function 52
EFFECTS OF TAURINE DEPLETION ON MEMBRANE ELECTIRCL PROPERTIES OF RAT SKELETAL MUSCLE. 52
Block of renal CLC-K channels by phenoxy-alkyl derivatives of clofibric acid 52
Skeletal muscle disuse fiber type-dependent enhancement of Na+ channel expression 50
null 49
Pharmacological interventions for the changes of chloride channel conductance of aging rat skeletal muscle 46
Modification of resting chloride conductance during and after recovery from hindlimb unloading 45
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ 44
Farmaci per il trattamento delle malattie muscolari 43
Excitation-contraction coupling is altered in skeletal muscle of dystrophic mdx mouse 42
Cyclic amidine analogs of taurine and homotaurine: synthesis and effects on rat skeletal muscle 41
Molecular mechanisms responsible for fluvastatin and fenofibrateinduced reduction of resting membrane chloride conductance in rat skeletal muscle 41
On ground preflight studies on skeletal muscle from mice kept in the Mouse Drawer System (MDS) 40
Role of tumour necrosis factor alpha, but not of cyclo-oxygenase-2-derived eicosanoids, on functional and morphological indices of dystrophic progression in mdx mice: a pharmacological approach 40
Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse 39
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 38
Stereoselective effects of a new analogs of clofibric acid on chloride channel conductance of rat skeletal muscle fibers 37
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading 36
Protein kinase C-dependent modulation of skeletal muscle resting chloride conductance is fiber type-specific and changes during rat hindlimb-unloading 35
An olive oil-derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function 35
Potential risk of myopathy by HMG-CoA reductase inhibitors: a comparison of pravastatin and simvastatin effects on membrane electrical properties of rat skeletal muscle fibers 34
Totale 7.618
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Categoria #
all - tutte 34.237
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.237
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.495 0 0 58 185 203 116 211 171 242 103 150 56
2020/20211.279 145 75 84 116 107 46 69 77 107 203 160 90
2021/2022894 33 159 9 32 49 48 53 36 83 54 142 196
2022/20231.392 218 138 106 121 167 201 5 151 201 6 44 34
2023/2024805 35 94 19 41 41 86 147 275 3 11 6 47
2024/2025254 78 35 141 0 0 0 0 0 0 0 0 0
Totale 8.159