A series of amidinosulfonic acids IIIa-f, analogs of taurine and homotaurine, was synthesized by reacting 2-aminoethane or 3-aminopropane sulfonic acid with lactim ethers Ia-c and then cyclized to sultams IVa-c and Vd-f. The effects of some selected amidinosulfonic acids III on membrane ionic conductances of rat skeletal muscle are described.

Cyclic amidine analogs of taurine and homotaurine: synthesis and effects on rat skeletal muscle

CAROTTI, Angelo;PIERNO, Sabata;TRICARICO, Domenico;DE LUCA, Annamaria;CONTE, Diana
1994-01-01

Abstract

A series of amidinosulfonic acids IIIa-f, analogs of taurine and homotaurine, was synthesized by reacting 2-aminoethane or 3-aminopropane sulfonic acid with lactim ethers Ia-c and then cyclized to sultams IVa-c and Vd-f. The effects of some selected amidinosulfonic acids III on membrane ionic conductances of rat skeletal muscle are described.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/133076
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