IRIS
PERRINI, SEBASTIO
 Distribuzione geografica
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Continente #
NA - Nord America 8.241
AS - Asia 3.764
EU - Europa 2.778
SA - Sud America 954
AF - Africa 141
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.891
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Nazione #
US - Stati Uniti d'America 8.116
SG - Singapore 1.658
CN - Cina 1.013
BR - Brasile 822
IT - Italia 580
SE - Svezia 546
HK - Hong Kong 506
RU - Federazione Russa 421
DE - Germania 316
UA - Ucraina 248
VN - Vietnam 227
FI - Finlandia 184
GB - Regno Unito 160
FR - Francia 94
IN - India 92
CA - Canada 61
CI - Costa d'Avorio 60
AR - Argentina 51
BE - Belgio 42
ID - Indonesia 42
MX - Messico 42
BD - Bangladesh 41
NL - Olanda 36
ES - Italia 31
AT - Austria 30
PL - Polonia 30
JP - Giappone 28
IQ - Iraq 27
TR - Turchia 22
IE - Irlanda 21
EC - Ecuador 20
PK - Pakistan 19
EG - Egitto 18
MA - Marocco 17
ZA - Sudafrica 17
UZ - Uzbekistan 14
VE - Venezuela 14
UY - Uruguay 12
AE - Emirati Arabi Uniti 11
LT - Lituania 9
CL - Cile 8
CO - Colombia 8
PE - Perù 8
PY - Paraguay 8
AZ - Azerbaigian 7
JM - Giamaica 7
AU - Australia 6
IL - Israele 6
KE - Kenya 6
TN - Tunisia 6
JO - Giordania 5
KZ - Kazakistan 5
SA - Arabia Saudita 5
CZ - Repubblica Ceca 4
DZ - Algeria 4
IR - Iran 4
LB - Libano 4
MY - Malesia 4
PH - Filippine 4
BO - Bolivia 3
BY - Bielorussia 3
CH - Svizzera 3
DO - Repubblica Dominicana 3
HU - Ungheria 3
KG - Kirghizistan 3
KR - Corea 3
NP - Nepal 3
PA - Panama 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AL - Albania 2
AM - Armenia 2
BB - Barbados 2
BG - Bulgaria 2
EU - Europa 2
HN - Honduras 2
HR - Croazia 2
KW - Kuwait 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
RS - Serbia 2
TW - Taiwan 2
AG - Antigua e Barbuda 1
AO - Angola 1
BH - Bahrain 1
BW - Botswana 1
BZ - Belize 1
CD - Congo 1
CR - Costa Rica 1
ET - Etiopia 1
GA - Gabon 1
GH - Ghana 1
GR - Grecia 1
GT - Guatemala 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
LY - Libia 1
MC - Monaco 1
MD - Moldavia 1
MG - Madagascar 1
Totale 15.881
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Città #
Ashburn 915
Singapore 888
Chandler 756
Fairfield 673
Woodbridge 612
Jacksonville 599
Hong Kong 496
Nyköping 440
Houston 375
Ann Arbor 325
Cambridge 310
Beijing 283
Seattle 250
Dearborn 230
Wilmington 218
Roxbury 174
Bari 166
Lawrence 163
Nanjing 161
New York 161
Los Angeles 132
Dallas 112
Boardman 108
Des Moines 98
Ho Chi Minh City 83
Inglewood 75
Brooklyn 67
Princeton 66
São Paulo 66
Abidjan 60
Munich 59
Buffalo 55
Hebei 47
Santa Clara 46
Helsinki 44
San Diego 43
Brussels 42
London 42
Nanchang 41
Jiaxing 39
Hanoi 38
Rio de Janeiro 35
Moscow 34
Shenyang 34
Jakarta 31
Falkenstein 29
Hefei 29
Frankfurt am Main 27
Rome 27
Guangzhou 25
Redwood City 25
Kunming 24
Paris 24
Belo Horizonte 23
Tianjin 23
Phoenix 22
Montreal 20
Jinan 19
Pune 19
Tokyo 19
Dublin 18
Nuremberg 18
Warsaw 18
Changsha 17
Chicago 17
San Francisco 17
Chennai 16
Atlanta 15
Poplar 14
Porto Alegre 14
Shanghai 14
Toronto 14
Vienna 14
Zhengzhou 14
Amsterdam 13
Denver 13
Giza 13
Turku 13
Washington 13
Boston 12
Campinas 12
Manchester 12
Trinitapoli 12
Council Bluffs 11
Mexico City 11
Milan 11
Montevideo 11
Stockholm 11
Tashkent 11
Wuhan 11
Baghdad 10
Brasília 10
Curitiba 10
Falls Church 10
Haiphong 10
Orem 10
Hải Dương 9
Johannesburg 9
Naples 9
Norwalk 9
Totale 10.553
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Nome #
Long-term exposure of pancreatic β-cells to palmitate results in SREBP-1C-dependent decreases in GLP-1 receptor signaling via CREB and AKT and insulin secretory response 197
Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity 196
Correction of intermittent hypoxia reduces inflammation in obese subjects with obstructive sleep apnea 190
Abnormalities of insulin-like growth factor-l Signaling and Impaired Cell Proliferation in Osteoblasts from Subjects with Osteoporosis 187
Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases 186
Diabetes and cancer: pathophysiological fundamentals of a 'dangerous affair' 171
Insulin and Insulin Receptors in Adipose Tissue Development 159
Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis 156
Irisin Increases the Expression of Anorexigenic and Neurotrophic Genes in Mouse Brain 155
GLP-1 Receptor Activation Inhibits Palmitate-Induced Apoptosis via Ceramide in Human Cardiac Progenitor Cells 154
The p66Shc Protein Controls Redox Signaling and Oxidation-Dependent DNA Damage in Human Liver Cells 149
The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells 148
Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway. 145
Dehydroepiandrosterone stimulates glucose uptake in human and murine adipocytes by inducing GLUT1 and GLUT4 translocation to the plasma membrane 131
NANOG plays a hierarchical role in the transcription network regulating the pluripotency and plasticity of adipose tissue-derived stem cells 130
Distribution of cardiovascular disease and retinopathy in patients with type 2 diabetes according to different classification systems for chronic kidney disease: A cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study 128
Glucagon-Like Peptide-1 Counteracts Oxidative Stress-Dependent Apoptosis of Human Cardiac Progenitor Cells by Inhibiting the Activation of the c-Jun N-terminal Protein Kinase Signaling Pathway 126
Differences in gene expression and cytokine release profiles highlight the heterogeneity of distinct subsets of adipose tissue-derived stem cells in the subcutaneous and visceral adipose tissue in humans. 125
Effects of Extra Virgin Olive Oil Polyphenols on Pancreatic Beta-Cell Function and Survival 125
Efficacy and safety of flash glucose monitoring in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis 125
Gender differences in cardiovascular disease risk factors, treatments and complications in patients with type 2 diabetes: the RIACE Italian multicentre study. 124
Decreased IRS phosphorylation and altered Erk activation in osteoblasts from osteoporotic subjects. 122
The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis 121
Ubc9 regulation of glucose transport in 3T3-L1 adipocytes is differentiation-dependent. 120
Biological specificity of visceral adipose tissue and therapeutic intervention 120
Adipose tissue precursor cells 116
Correction of Intermittent Hypoxia with CPAP Improves Cardiometabolic Abnormalities, and Systemic and Adipose Tissue Inflammation in Obese Subjects with Obstructive Sleep Apnea. 115
TNFα Signals via p66(Shc) to Induce E-Selectin, Promote Leukocyte Transmigration and Enhance Permeability in Human Endothelial Cells 115
The myokine irisin is released in response to saturated fatty acids and promotes pancreatic β-cell survival and insulin secretion 115
Involvement of the p66Shc protein in glucose transport regulation in skeletal muscle myoblasts 114
Effects of CPAP on testosterone levels in patients with obstructive sleep apnea: a meta-analysis study 113
Apoptotic and survival signals triggered by high glucose in human mesangial cells. 112
The SUMO-conjugating enzyme Ubc9 is essential for insulin-responsive glucose transport in adipocytes. 112
Associated hormonal declines in aging: DHEAS 112
Chronic palmitate excess results in reduced exendin-4 action and signalling via CREB and Akt in pancreatic beta cells 111
Dysmetabolic adipose tissue in obesity: morphological and functional characteristics of adipose stem cells and mature adipocytes in healthy and unhealthy obese subjects 110
Role of p66Shc in Cytokine-Mediated Leukocyte Recruitment by Endothelial Cells 109
Irisin Enhances Pancreatic Beta-Cell Survival and Insulin Secretion and Can Mediate the Metabolic Cross Talk between the Skeletal Muscle and Endocrine Pancreas 109
Abnormalities in IGF-I signalling and impaired cell proliferation in osteoblasts from patients with osteoporosis. 108
Human adipose tissue stem cells: relevance in the pathophysiology of obesity and metabolic diseases and therapeutic applications. 108
Effects of irisin on leptin and ghrelin secretion and expression of the major appetite regulators in mouse brain 107
Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling 106
Insulin signaling in human visceral and subcutaneous adipose tissue in vivo 106
Comparison of Distinct GLP-1 Receptor Agonists in Palmitate-induced Incretin Resistance of Pancreatic Beta Cells 106
Cross-Talk between PPARgamma and Insulin Signaling and Modulation of Insulin Sensitivity 103
Efficacy and Safety of Different Hybrid Closed Loop Systems for Automated Insulin Delivery in People With Type 1 Diabetes: A Systematic Review and Network Meta-Analysis 102
Human adipose tissue precursor cells: a new factor linking regulation of fat mass to obesity and type 2 diabetes? 101
The myokine irisin is released in response to saturated fatty acids and enhances pancreatic beta cell survival and insulin secretion 100
Involvement of Actin Cytoskeleton in Free Fatty Acid-induced Beta-Cell Death. 99
Cardiovascular and Renal Effectiveness of GLP-1 Receptor Agonists vs. Other Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Real-World Studies 99
Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts 97
Role of p66Shc in cytokine-mediated leukocyte recruitment by endothelial cells. 96
Role of UBC9 in the regulation of the adipogenic program in 3T3-L1 adipocytes 96
p66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress 96
The p66Shc protein mediates saturated fatty acid-induced insulin resistance in pancreatic beta cells 96
58th EASD Annual Meeting of the European Association for the Study of Diabetes : Stockholm, Sweden, 19 - 23 September 2022 95
Key role of the p66Shc protein in the regulation of the glucose transport system in skeletal muscle cells. 95
Functional loss of pancreatic islets in type 2 diabetes: How can we halt it? 95
Characterization of the gut microbiota and metabolome in healthy and unhealthy obese patients 94
A telemedicine-based approach with real-time transmission of blood glucose data improves metabolic control in insulin-treated diabetes: the DIAMONDS randomized clinical trial 94
Involvement of actin cytoskeleton in free fatty acid-induced beta cell death 94
Reduction of hypoglycaemia, lifestyle modifications and psychological distress during lockdown following SARS-CoV-2 outbreak in type 1 diabetes 94
TNF alpha impairs insulin signaling in pancreatic beta-cells through JNK-dependent serine phosphorylation of IRS-2. 93
Insulin signalling in human adipose tissue 93
Irisin improves the secretory defects of pancreatic islets from type 2 diabetic subjects 92
The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells 90
null 89
The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions 88
Exercise-induced protein kinase C isoform-specific activation in human skeletal muscle 88
Role of the p66Shc isoform in IGF-I receptor signaling through MEK/ERK and regulation of actin cytoskeleton in rat myoblasts 88
GLP-1 receptor agonists modulate TNFα signaling and TNFα-induced apoptosis in INS-1 beta-cells. 88
Requirement of the SUMO-conjugating enzyme Ubc9 for insulin-responsive glucose transport in adipocytes. 87
Differences in the characteristic of gut microbiota and metabolome in adult subjects with healthy and unhealthy obesity 86
Role of p66Shc in the modulation of oxidative stress in human liver cells. 86
Role of Ubc9 in the development of insulin-responsive glucose transport during adipocyte differentiation. 86
Commentary: Glucose control: Not just a bystander in GLP-1RA-mediated cardiovascular protection 86
Diabetes in the Time of COVID-19: A Twitter-Based Sentiment Analysis 84
Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart 83
Impaired leptin signalling in obesity: Is leptin a new thermolipokine? 83
Role of the SUMO-conjugating enzyme Ubc9 in adipocyte differentiation 82
Enhanced Adipo/Lipogenic Potential of Human Adipose Tissue Stem Cells in Obesity 82
Body fat accumulation is possibly responsible for lower dehydroepiandrosterone circulating levels in premenopausal obese women 82
Il tessuto adiposo viscerale: fisiopatologia e modulazione farmacologica. 81
The p66Shc isoform mediates FFA-induced apoptosis in pancreatic beta-cells. 81
Mitogenic and metabolic responses to IGF-I are dysregulated in osteoblasts from osteoporotic patients. 80
Dehydroepiandrosterone exerts distinct regulatory effects on the glucose transport system in fat and muscle cells. 80
Mechanisms of glucose transport stimulation by dehydroepiandrosterone (DHEA) in cultured adipocytes. 79
Specific metabolic effects of insulin detemir in human visceral adipocytes differentiated in vitro from precursor stromal cells. 79
The Adipogenic Potential of Human Adipose Tissue Precursor Cells Is Regulated in a Fat Depot- and BMI-Dependent Manner 79
[Fetal growth restriction and insulin-like growth factors] 78
Opposite effects of dehydroepiandrosterone (DHEA) on the glucose transport system in fat and skeletal muscle cells. 77
Divergent regulation of GLUT4 and GLUT1 by mUbc9, a glucose transporter interactive ubiquitin-conjugating enzyme. 77
he SIAMS-ED Trial: A National, Independent, Multicentre Study on Cardiometabolic and Hormonal Impairment of Men with Erectile Dysfunction Treated with Vardenafil 77
Effects of extra virgin olive oil polyphenols on beta-cell function and survival 77
Enhanced adipo/lipogenic potential oh human adipose tissue stem cells in obesity. 76
Essential role of the SUMO-conjugating enzyme Ubc9 for insulin-stimulated glucose transport in adipocytes. 76
The adipogenic potential of human adipose tissue precursor cells is regulated in a fat depot- and BMI- dependent manner. 76
Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans 76
The p66Shc isoform controls the actin cytoskeleton and the glucose transport system in skeletal muscle cells. 76
The SUMO-conjugating enzyme Ubc9 is key for GLUT4 levels and insulin-stimulated glucose transport in 3T3-L1 adipocytes. 75
Totale 10.676
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Categoria #
all - tutte 72.849
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.849
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021684 0 0 0 0 0 56 107 97 140 168 59 57
2021/20221.217 39 158 8 95 47 56 31 75 79 73 223 333
2022/20232.083 259 227 117 173 273 340 29 218 365 18 36 28
2023/2024716 62 134 37 54 87 174 8 54 5 27 6 68
2024/20253.296 53 45 264 108 109 326 290 348 172 143 509 929
2025/20263.698 1.082 379 431 838 877 91 0 0 0 0 0 0
Totale 16.285