IRIS
MARGIOTTA, NICOLA
 Distribuzione geografica
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Continente #
NA - Nord America 6.864
EU - Europa 1.462
AS - Asia 725
OC - Oceania 25
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 2
AF - Africa 1
Totale 9.084
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Nazione #
US - Stati Uniti d'America 6.850
CN - Cina 662
SE - Svezia 397
UA - Ucraina 285
DE - Germania 213
IT - Italia 204
FI - Finlandia 163
GB - Regno Unito 89
FR - Francia 37
AU - Australia 21
IE - Irlanda 20
SG - Singapore 18
BE - Belgio 17
IN - India 15
CA - Canada 12
NL - Olanda 7
IR - Iran 6
CZ - Repubblica Ceca 5
VN - Vietnam 5
HK - Hong Kong 4
HU - Ungheria 4
KR - Corea 4
NZ - Nuova Zelanda 4
RU - Federazione Russa 4
BG - Bulgaria 3
ES - Italia 3
AT - Austria 2
CO - Colombia 2
EU - Europa 2
JP - Giappone 2
RS - Serbia 2
BD - Bangladesh 1
BO - Bolivia 1
BR - Brasile 1
CH - Svizzera 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
HR - Croazia 1
ID - Indonesia 1
IL - Israele 1
IQ - Iraq 1
JM - Giamaica 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
PL - Polonia 1
PR - Porto Rico 1
PT - Portogallo 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
UZ - Uzbekistan 1
Totale 9.084
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Città #
Fairfield 983
Chandler 723
Jacksonville 676
Woodbridge 580
Ashburn 458
Houston 444
Seattle 396
Cambridge 382
Wilmington 328
Nyköping 313
Ann Arbor 243
Nanjing 197
Lawrence 164
Roxbury 160
Boardman 110
Des Moines 105
New York 94
Beijing 85
Princeton 74
Bari 68
Nanchang 62
Brooklyn 41
San Diego 39
Shenyang 35
Inglewood 34
Hebei 30
Jiaxing 26
Dearborn 25
Helsinki 23
Rome 23
Tianjin 22
Changsha 21
Paris 21
Dublin 20
London 20
Brussels 17
Kunming 16
San Francisco 15
Shanghai 15
Guangzhou 13
Wuhan 13
Melbourne 12
Molfetta 12
Auburn Hills 11
Los Angeles 10
Washington 10
Zhengzhou 10
Jinan 9
Singapore 9
Toronto 9
Leawood 8
Arzano 7
Ningbo 6
Norwalk 6
San Mateo 6
Wuxi 6
Ardabil 5
Augusta 5
Bologna 5
Falls Church 5
Hefei 5
Pune 5
Taizhou 5
Amsterdam 4
Budapest 4
Marseille 4
Noci 4
Redmond 4
Sydney 4
Tappahannock 4
Yiwu 4
Brno 3
Canberra 3
Chicago 3
Edinburgh 3
Lanzhou 3
Monmouth Junction 3
Orange 3
Ansbach 2
Belgrade 2
Berlin 2
Bogotá 2
Brisbane 2
Cassino 2
Central 2
Changchun 2
Chongqing 2
Delhi 2
Dong Ket 2
Frankfurt am Main 2
Fuzhou 2
Hanoi 2
Hanover 2
Kilburn 2
Naples 2
Napoli 2
Simi Valley 2
Sofia 2
Tokyo 2
Vienna 2
Totale 7.377
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Nome #
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 124
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 122
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 115
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 111
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 111
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 109
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 108
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum-bisphosphonate complexes in the treatment of bone tumors: A mini-review 102
DNA fragment conformations in adducts with Kiteplatin 100
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 100
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 99
Method of treating colorectal cancer. 99
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 99
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 99
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 98
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 97
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 93
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 93
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 93
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 92
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 92
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 90
Novel Therapeutic Agents for Bone Resorption. Part 1. Synthesis and Protonation Thermodynamics of Poly(amido-amine)s Containing Bis-phosphonate Residues 90
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 89
Unusual DNA Binding Properties of Chelate Ring-opening Platinum Complexes 88
null 88
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 88
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 87
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 86
Computational evidence for structural consequences of kiteplatin damage on DNA 86
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds. 83
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 82
Mono- and bis-guanosine adducts of platinum complexes with carrier ligands having in-plane steric bulk: The case of 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline 81
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 81
Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)] 80
Strong, Rapid Binding of a Platinum Complex to Thymine and Uracil Under Physiological Conditions 80
Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug 79
null 79
Insights into the role of the lead/surfactant ratio in the formation and passivation of cesium lead bromide perovskite nanocrystals 79
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 78
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 78
null 78
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma 77
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 77
Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. 76
NMR investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives. 75
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 75
null 74
The influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand 74
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null 72
Structure and dynamics of a Platinum(II) aminophosphine complex and its nucleobase adducts 72
Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals 72
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer. 71
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Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 69
Platinum(II) Complexes with Bioactive Carrier Ligands Having High Affinity for the Translocator Protein 66
Dinuclear Pt(II)-bisphosphonates complexes: useful precursors of multinuclear or higher oxidation state platinum drugs. 65
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity 65
Platinum(II) Complexes with Antitumoral/Antiviral Aromatic Heterocycles: Effect of Glutathione upon in Vitro Cell Growth Inhibition 64
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug 64
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One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 63
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 61
null 60
Recent findings in the chemistry of five-coordinate platinum(II) alkyne complexes. 59
Platinum–bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis 58
9[(aminoalkyl)amino]nitroacridines: kinetic vs thermodynamic interactions towards platinum(II) and factors ruling their tautomeric equilibrium. 57
Activation of antitumoral platinum prodrugs for the local treatment of bone tumors by inclusion in bioactive inorganic matrices. 56
Antitumor trans iminoether platinum di- and oligonucleotide adducts studied by NMR. 56
PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study 56
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 54
Drug Targeting and Delivery of Platinum Chemotherapeutics ☆ 54
A novel Platinum(II) complex tethered to a ligand having high affinity for the Peripheral Benzodiazepine Receptor 53
Synthesis, characterization, and binding to the translocator protein (18 kDa, TSPO) of a new rhenium complex as a model of radiopharmaceutical agents. 53
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 53
Implementation of Sustainable Solvents in Green Polymerization Approaches 53
Back to the future with Kiteplatin: an efficacious drug against oxaliplatin-refractory colorectal cancer. 51
Dinuclear Pt(II)-bisphosphonate complexes:useful building blocks for the preparation of multinuclear or higher oxidation state platinum drugs. 48
New Pt and Re complexes targeting the Translocator Protein 18 kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents 48
Inclusion of Antitumoral platinum drugs in bioactive inorganic matrices to be used for the local treatment of bone tumors. 47
Assessing inter-nucleot(s)ide interactions by conformational studies of adducts between platinum complexes with carrier ligand unable to form H-bonds and guanine derivatives. 46
Calcium-modulated release of active platinum antitumor compounds from sol-gel silica xerogels. 46
Platinum-Based Antitumor Drugs Containing Enantiomerically Pure alpha-Trifluoromethyl Alanine as Ligand 45
Monofunctional platinum(II) complexes and moleules of biological relevance: evaluation of steric and electronic factors in the competition for binding sites. 45
H-Bond interactions between the NH of carrier ligand (Me3dien) and the O6 or the 5'-phosphate of guanine nucleotides in platinum complexes with a single guanine ligand. 44
Slowing down dynamic motions in cisplatinum analogues. 44
Antitumor drugs delivery by bone substitute biomimetic hydroxyapatite nanocrystals. 43
The dynamic of metal chelate ring-opening: Pt(II) aminophosphine complexes and nucleotide adducts. 42
Bioactive Inorganic Matrices for the Local Delivery of Platinum-based Prodrugs in the Treatment of Bone Tumors 42
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective metal-chelating ligand 42
In vitro targeting and imaging the Translocator Protein TSPO 18-kDa through new coordination complexes of transition metals. 42
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy 42
Controlled release of platinum complexes from biomimetic hydroxyapatite nanocrystals. 41
New platinum-containing bisphosphonates as targeted metallopharmaceuticals for malignant mesothelioma. 41
Penciclovir and Famcyclovir Pt(II) complexes. 41
TSPO-seeking Pt(II)- and Pt(IV)-complexes 40
New Pt and Re complexes targeting the Translocator Protein 18kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents. 40
Totale 7.220
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Categoria #
all - tutte 38.172
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.172
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.622 439 153 62 188 280 158 313 217 353 201 200 58
2020/20211.567 169 85 165 78 136 85 171 101 159 239 102 77
2021/20221.190 37 176 11 10 48 66 45 58 90 79 188 382
2022/20231.836 299 167 94 178 254 238 24 188 304 23 42 25
2023/2024586 58 111 26 55 78 146 15 5 15 12 4 61
2024/202589 89 0 0 0 0 0 0 0 0 0 0 0
Totale 9.344