IRIS
MARGIOTTA, NICOLA
 Distribuzione geografica
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Continente #
NA - Nord America 8.651
AS - Asia 3.750
EU - Europa 2.498
SA - Sud America 1.094
AF - Africa 138
OC - Oceania 29
Continente sconosciuto - Info sul continente non disponibili 3
Totale 16.163
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Nazione #
US - Stati Uniti d'America 8.526
SG - Singapore 1.514
CN - Cina 961
BR - Brasile 875
HK - Hong Kong 520
SE - Svezia 402
RU - Federazione Russa 339
IT - Italia 325
FI - Finlandia 300
UA - Ucraina 291
DE - Germania 283
VN - Vietnam 214
FR - Francia 203
GB - Regno Unito 150
IN - India 113
AR - Argentina 71
BD - Bangladesh 61
CA - Canada 60
ID - Indonesia 50
TR - Turchia 48
IQ - Iraq 44
MX - Messico 44
ZA - Sudafrica 44
EC - Ecuador 37
CO - Colombia 33
NL - Olanda 33
IE - Irlanda 32
VE - Venezuela 32
MA - Marocco 30
PK - Pakistan 30
SA - Arabia Saudita 27
ES - Italia 26
AU - Australia 24
PL - Polonia 23
JP - Giappone 20
BE - Belgio 19
CL - Cile 18
PH - Filippine 16
UZ - Uzbekistan 16
CI - Costa d'Avorio 14
KE - Kenya 14
MY - Malesia 14
AT - Austria 13
JO - Giordania 12
PY - Paraguay 11
LT - Lituania 10
IR - Iran 9
TN - Tunisia 9
BO - Bolivia 8
CZ - Repubblica Ceca 8
KR - Corea 8
AE - Emirati Arabi Uniti 7
AZ - Azerbaigian 7
BG - Bulgaria 7
BH - Bahrain 7
KZ - Kazakistan 7
OM - Oman 7
NP - Nepal 6
EG - Egitto 5
ET - Etiopia 5
HU - Ungheria 5
UY - Uruguay 5
CR - Costa Rica 4
DZ - Algeria 4
JM - Giamaica 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
RS - Serbia 4
AL - Albania 3
GE - Georgia 3
IL - Israele 3
LB - Libano 3
PS - Palestinian Territory 3
PT - Portogallo 3
QA - Qatar 3
SN - Senegal 3
SY - Repubblica araba siriana 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
BY - Bielorussia 2
CM - Camerun 2
EE - Estonia 2
EU - Europa 2
HN - Honduras 2
HR - Croazia 2
NI - Nicaragua 2
PA - Panama 2
RO - Romania 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
SR - Suriname 2
TW - Taiwan 2
AM - Armenia 1
BB - Barbados 1
BN - Brunei Darussalam 1
CH - Svizzera 1
CY - Cipro 1
DK - Danimarca 1
FJ - Figi 1
GA - Gabon 1
Totale 16.143
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Città #
Fairfield 983
Ashburn 782
Singapore 758
Chandler 721
Jacksonville 672
Woodbridge 580
Hong Kong 514
Houston 452
San Jose 452
Seattle 397
Cambridge 382
Wilmington 328
Nyköping 311
Ann Arbor 233
Beijing 206
Nanjing 195
Lawrence 164
Roxbury 160
Helsinki 149
Lauterbourg 145
New York 137
Boardman 122
Bari 106
Des Moines 106
Dallas 85
Los Angeles 80
São Paulo 79
Princeton 74
Ho Chi Minh City 69
Nanchang 62
Brooklyn 56
Hanoi 56
Santa Clara 56
Council Bluffs 42
San Diego 40
London 36
Rio de Janeiro 36
Buffalo 35
Shenyang 35
Inglewood 34
Dublin 30
Jakarta 30
Hebei 29
Jiaxing 26
Dearborn 25
Rome 25
San Francisco 25
Chicago 24
Munich 24
Baghdad 23
Changsha 23
Moscow 23
Paris 23
Tianjin 23
Warsaw 21
Guangzhou 20
Montreal 20
Brussels 19
Johannesburg 19
Quito 19
Amsterdam 18
Toronto 18
Kunming 17
Belo Horizonte 16
Mexico City 16
Nuremberg 16
Orem 16
Shanghai 16
Tokyo 16
Brasília 15
Frankfurt am Main 15
Abidjan 14
Boston 14
Denver 14
Molfetta 14
Phoenix 14
Zhengzhou 14
Chennai 13
Melbourne 13
Tashkent 13
Wuhan 13
Jinan 12
Porto Alegre 12
Turku 12
Amman 11
Ankara 11
Auburn Hills 11
Curitiba 11
Mumbai 11
Nairobi 11
Washington 11
Atlanta 10
Casablanca 10
Charlotte 10
Dhaka 10
Lahore 10
Santiago 10
Dammam 9
Falkenstein 9
Haiphong 9
Totale 10.916
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Nome #
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 207
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 194
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 182
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 179
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 177
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 175
Insights into the role of the lead/surfactant ratio in the formation and passivation of cesium lead bromide perovskite nanocrystals 170
Method of treating colorectal cancer. 164
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 160
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 158
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 154
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 150
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 149
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 148
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 145
DNA fragment conformations in adducts with Kiteplatin 143
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 138
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 137
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 136
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 134
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 133
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum-bisphosphonate complexes in the treatment of bone tumors: A mini-review 132
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 131
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 131
First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer 130
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 129
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 129
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 127
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 125
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 123
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 123
Novel Therapeutic Agents for Bone Resorption. Part 1. Synthesis and Protonation Thermodynamics of Poly(amido-amine)s Containing Bis-phosphonate Residues 123
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity 122
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 121
Unusual DNA Binding Properties of Chelate Ring-opening Platinum Complexes 120
Activation of antitumoral platinum prodrugs for the local treatment of bone tumors by inclusion in bioactive inorganic matrices. 120
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy 120
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 119
Dinuclear Pt(II)-bisphosphonates complexes: useful precursors of multinuclear or higher oxidation state platinum drugs. 118
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 118
PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study 117
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 117
Computational evidence for structural consequences of kiteplatin damage on DNA 116
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 116
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 115
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 114
Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug 114
Antitumor trans iminoether platinum di- and oligonucleotide adducts studied by NMR. 112
9[(aminoalkyl)amino]nitroacridines: kinetic vs thermodynamic interactions towards platinum(II) and factors ruling their tautomeric equilibrium. 111
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds. 111
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 111
Mono- and bis-guanosine adducts of platinum complexes with carrier ligands having in-plane steric bulk: The case of 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline 111
Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals 111
Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)] 110
A novel Platinum(II) complex tethered to a ligand having high affinity for the Peripheral Benzodiazepine Receptor 110
Back to the future with Kiteplatin: an efficacious drug against oxaliplatin-refractory colorectal cancer. 109
Strong, Rapid Binding of a Platinum Complex to Thymine and Uracil Under Physiological Conditions 107
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring 106
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases 104
Assessing inter-nucleot(s)ide interactions by conformational studies of adducts between platinum complexes with carrier ligand unable to form H-bonds and guanine derivatives. 102
Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model 101
NMR investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives. 99
Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. 97
Structure and dynamics of a Platinum(II) aminophosphine complex and its nucleobase adducts 95
Platinum(II) Complexes with Bioactive Carrier Ligands Having High Affinity for the Translocator Protein 94
The influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand 94
Dinuclear Pt(II)-bisphosphonate complexes:useful building blocks for the preparation of multinuclear or higher oxidation state platinum drugs. 92
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma 92
Platinum(II) Complexes with Antitumoral/Antiviral Aromatic Heterocycles: Effect of Glutathione upon in Vitro Cell Growth Inhibition 92
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer. 92
Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration 90
Antitumor drugs delivery by bone substitute biomimetic hydroxyapatite nanocrystals. 90
Bioactive Inorganic Matrices for the Local Delivery of Platinum-based Prodrugs in the Treatment of Bone Tumors 88
Recent findings in the chemistry of five-coordinate platinum(II) alkyne complexes. 88
Platinum–bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis 88
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug 88
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Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells 88
A new synthetic approach for size-tunable and stable CsPbBr3 nanocubes with near-unity photoluminescence quantum yield 85
Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin 84
Implementation of Sustainable Solvents in Green Polymerization Approaches 82
Synthesis, characterization, and binding to the translocator protein (18 kDa, TSPO) of a new rhenium complex as a model of radiopharmaceutical agents. 81
New Pt and Re complexes targeting the Translocator Protein 18 kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents 79
H-Bond interactions between the NH of carrier ligand (Me3dien) and the O6 or the 5'-phosphate of guanine nucleotides in platinum complexes with a single guanine ligand. 79
Inclusion of Antitumoral platinum drugs in bioactive inorganic matrices to be used for the local treatment of bone tumors. 79
Drug Targeting and Delivery of Platinum Chemotherapeutics ☆ 79
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Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin 78
Platinum-Based Antitumor Drugs Containing Enantiomerically Pure alpha-Trifluoromethyl Alanine as Ligand 78
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Bone tumor–targeted delivery of theranostic 195mPt-bisphosphonate complexes promotes killing of metastatic tumor cells 78
Calcium-modulated release of active platinum antitumor compounds from sol-gel silica xerogels. 77
Monofunctional platinum(II) complexes and moleules of biological relevance: evaluation of steric and electronic factors in the competition for binding sites. 77
Conformational study on the five member chelate ring of new platinum complexes containing diethyl (methylsulfinyl)methylphosphonate as carrier ligand for bone tumors. 76
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New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity 73
In vitro targeting and imaging the Translocator Protein TSPO 18-kDa through new coordination complexes of transition metals. 72
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Molecular insights into growth and time evolution of surface states of CsPbBr3 nanoparticles synthesized by scalable room temperature approach 71
Totale 11.278
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Categoria #
all - tutte 67.617
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.617
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021414 0 0 0 0 0 0 0 0 0 237 101 76
2021/20221.185 36 175 11 9 48 66 44 57 90 79 188 382
2022/20231.825 298 166 94 177 251 238 24 188 300 23 41 25
2023/2024579 58 110 26 54 77 142 15 5 15 12 4 61
2024/20252.635 98 39 221 83 106 174 240 208 104 173 371 818
2025/20264.658 711 263 333 649 531 332 640 167 610 422 0 0
Totale 16.501