IRIS
MARGIOTTA, NICOLA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 6.964
EU - Europa 1.631
AS - Asia 993
OC - Oceania 25
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 2
AF - Africa 1
Totale 9.621
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.946
CN - Cina 682
SE - Svezia 393
UA - Ucraina 283
SG - Singapore 264
DE - Germania 225
IT - Italia 214
FI - Finlandia 169
RU - Federazione Russa 134
GB - Regno Unito 96
FR - Francia 37
AU - Australia 21
IE - Irlanda 21
BE - Belgio 19
CA - Canada 15
IN - India 15
NL - Olanda 8
IR - Iran 6
CZ - Repubblica Ceca 5
HK - Hong Kong 5
VN - Vietnam 5
HU - Ungheria 4
KR - Corea 4
LT - Lituania 4
NZ - Nuova Zelanda 4
BG - Bulgaria 3
ES - Italia 3
AT - Austria 2
CO - Colombia 2
EU - Europa 2
JP - Giappone 2
RS - Serbia 2
AL - Albania 1
AM - Armenia 1
BD - Bangladesh 1
BO - Bolivia 1
BR - Brasile 1
CH - Svizzera 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
HR - Croazia 1
ID - Indonesia 1
IL - Israele 1
IQ - Iraq 1
JM - Giamaica 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
PA - Panama 1
PL - Polonia 1
PR - Porto Rico 1
PT - Portogallo 1
RO - Romania 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
UZ - Uzbekistan 1
Totale 9.621
Salva come PNG Salva come JPEG
Città #
Fairfield 983
Chandler 721
Jacksonville 671
Woodbridge 579
Ashburn 467
Houston 444
Seattle 395
Cambridge 382
Wilmington 327
Nyköping 311
Ann Arbor 233
Singapore 202
Nanjing 195
Lawrence 164
Roxbury 160
Boardman 122
Des Moines 105
New York 92
Beijing 85
Princeton 74
Bari 71
Nanchang 62
Brooklyn 41
San Diego 39
Shenyang 35
Inglewood 34
Santa Clara 32
Helsinki 30
Hebei 29
Jiaxing 26
Dearborn 25
London 24
Rome 23
Tianjin 22
Changsha 21
Dublin 21
Paris 21
Brussels 19
Los Angeles 18
Kunming 17
Guangzhou 15
San Francisco 15
Shanghai 15
Molfetta 14
Wuhan 13
Melbourne 12
Auburn Hills 11
Toronto 11
Zhengzhou 11
Jinan 10
Washington 10
Leawood 8
Munich 8
Arzano 7
Wuxi 7
Ningbo 6
Norwalk 6
San Mateo 6
Ardabil 5
Augusta 5
Bologna 5
Falls Church 5
Frankfurt am Main 5
Hefei 5
Pune 5
Taizhou 5
Amsterdam 4
Budapest 4
Marseille 4
Noci 4
Redmond 4
Sydney 4
Tappahannock 4
Yiwu 4
Brno 3
Canberra 3
Chicago 3
Edinburgh 3
Lanzhou 3
Leeds 3
Monmouth Junction 3
Orange 3
Ansbach 2
Belgrade 2
Berlin 2
Bogotá 2
Brisbane 2
Cassino 2
Central 2
Changchun 2
Chongqing 2
Clifton 2
Delhi 2
Dong Ket 2
Fuzhou 2
Hanoi 2
Hanover 2
Kilburn 2
Naples 2
Napoli 2
Totale 7.639
Salva come PNG Salva come JPEG
Nome #
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 133
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 128
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 119
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 118
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 115
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 115
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 109
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 106
DNA fragment conformations in adducts with Kiteplatin 106
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum-bisphosphonate complexes in the treatment of bone tumors: A mini-review 105
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 105
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 104
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 103
Method of treating colorectal cancer. 103
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 101
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 99
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 97
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 96
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 95
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 95
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 94
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 93
Novel Therapeutic Agents for Bone Resorption. Part 1. Synthesis and Protonation Thermodynamics of Poly(amido-amine)s Containing Bis-phosphonate Residues 93
Unusual DNA Binding Properties of Chelate Ring-opening Platinum Complexes 92
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 92
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 91
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 91
Insights into the role of the lead/surfactant ratio in the formation and passivation of cesium lead bromide perovskite nanocrystals 91
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 90
Computational evidence for structural consequences of kiteplatin damage on DNA 90
null 88
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds. 85
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 85
Mono- and bis-guanosine adducts of platinum complexes with carrier ligands having in-plane steric bulk: The case of 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline 85
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 85
Strong, Rapid Binding of a Platinum Complex to Thymine and Uracil Under Physiological Conditions 83
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 82
Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)] 82
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 82
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 81
Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug 81
NMR investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives. 79
null 79
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma 78
null 78
Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. 78
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 77
The influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand 75
Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals 75
null 74
Structure and dynamics of a Platinum(II) aminophosphine complex and its nucleobase adducts 74
null 73
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer. 73
null 72
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 72
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity 71
Dinuclear Pt(II)-bisphosphonates complexes: useful precursors of multinuclear or higher oxidation state platinum drugs. 70
null 70
null 69
Platinum(II) Complexes with Bioactive Carrier Ligands Having High Affinity for the Translocator Protein 68
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 68
Platinum(II) Complexes with Antitumoral/Antiviral Aromatic Heterocycles: Effect of Glutathione upon in Vitro Cell Growth Inhibition 66
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug 66
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 64
null 64
null 64
9[(aminoalkyl)amino]nitroacridines: kinetic vs thermodynamic interactions towards platinum(II) and factors ruling their tautomeric equilibrium. 63
Recent findings in the chemistry of five-coordinate platinum(II) alkyne complexes. 63
PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study 63
Activation of antitumoral platinum prodrugs for the local treatment of bone tumors by inclusion in bioactive inorganic matrices. 62
Antitumor trans iminoether platinum di- and oligonucleotide adducts studied by NMR. 62
Drug Targeting and Delivery of Platinum Chemotherapeutics ☆ 61
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 61
A novel Platinum(II) complex tethered to a ligand having high affinity for the Peripheral Benzodiazepine Receptor 60
null 60
Platinum–bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis 59
Back to the future with Kiteplatin: an efficacious drug against oxaliplatin-refractory colorectal cancer. 57
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 57
Implementation of Sustainable Solvents in Green Polymerization Approaches 56
Synthesis, characterization, and binding to the translocator protein (18 kDa, TSPO) of a new rhenium complex as a model of radiopharmaceutical agents. 54
Dinuclear Pt(II)-bisphosphonate complexes:useful building blocks for the preparation of multinuclear or higher oxidation state platinum drugs. 52
Inclusion of Antitumoral platinum drugs in bioactive inorganic matrices to be used for the local treatment of bone tumors. 52
Assessing inter-nucleot(s)ide interactions by conformational studies of adducts between platinum complexes with carrier ligand unable to form H-bonds and guanine derivatives. 50
New Pt and Re complexes targeting the Translocator Protein 18 kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents 50
Calcium-modulated release of active platinum antitumor compounds from sol-gel silica xerogels. 50
Platinum-Based Antitumor Drugs Containing Enantiomerically Pure alpha-Trifluoromethyl Alanine as Ligand 49
Monofunctional platinum(II) complexes and moleules of biological relevance: evaluation of steric and electronic factors in the competition for binding sites. 49
H-Bond interactions between the NH of carrier ligand (Me3dien) and the O6 or the 5'-phosphate of guanine nucleotides in platinum complexes with a single guanine ligand. 47
Slowing down dynamic motions in cisplatinum analogues. 47
Antitumor drugs delivery by bone substitute biomimetic hydroxyapatite nanocrystals. 47
The dynamic of metal chelate ring-opening: Pt(II) aminophosphine complexes and nucleotide adducts. 46
Bioactive Inorganic Matrices for the Local Delivery of Platinum-based Prodrugs in the Treatment of Bone Tumors 46
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy 46
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective metal-chelating ligand 45
In vitro targeting and imaging the Translocator Protein TSPO 18-kDa through new coordination complexes of transition metals. 45
Controlled release of platinum complexes from biomimetic hydroxyapatite nanocrystals. 44
New platinum-containing bisphosphonates as targeted metallopharmaceuticals for malignant mesothelioma. 44
Conformational study on the five member chelate ring of new platinum complexes containing diethyl (methylsulfinyl)methylphosphonate as carrier ligand for bone tumors. 44
Penciclovir and Famcyclovir Pt(II) complexes. 44
TSPO-seeking Pt(II)- and Pt(IV)-complexes 43
Totale 7.563
Salva come PNG Salva come JPEG
Categoria #
all - tutte 44.252
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.252
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.495 0 0 0 0 0 158 311 217 352 200 199 58
2020/20211.557 167 85 165 77 135 85 170 101 158 237 101 76
2021/20221.185 36 175 11 9 48 66 44 57 90 79 188 382
2022/20231.825 298 166 94 177 251 238 24 188 300 23 41 25
2023/2024579 58 110 26 54 77 142 15 5 15 12 4 61
2024/2025713 98 39 221 83 106 166 0 0 0 0 0 0
Totale 9.921