IRIS
MARGIOTTA, NICOLA
 Distribuzione geografica
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Continente #
NA - Nord America 10.643
AS - Asia 3.837
EU - Europa 3.474
SA - Sud America 1.112
Continente sconosciuto - Info sul continente non disponibili 363
AF - Africa 143
OC - Oceania 29
Totale 19.601
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Nazione #
US - Stati Uniti d'America 10.306
SG - Singapore 1.520
IT - Italia 1.229
CN - Cina 967
BR - Brasile 879
HK - Hong Kong 525
SE - Svezia 402
RU - Federazione Russa 348
FI - Finlandia 299
UA - Ucraina 292
DE - Germania 290
VN - Vietnam 213
FR - Francia 206
GB - Regno Unito 174
CA - Canada 145
IN - India 113
BD - Bangladesh 94
AR - Argentina 72
ID - Indonesia 52
TR - Turchia 49
MX - Messico 48
IQ - Iraq 44
ZA - Sudafrica 43
EC - Ecuador 40
CO - Colombia 37
NL - Olanda 36
VE - Venezuela 36
IE - Irlanda 32
ES - Italia 31
SA - Arabia Saudita 31
MA - Marocco 30
PK - Pakistan 30
PL - Polonia 25
AU - Australia 24
CR - Costa Rica 21
BE - Belgio 20
IL - Israele 20
JP - Giappone 20
LT - Lituania 19
PH - Filippine 19
CL - Cile 18
MY - Malesia 18
HN - Honduras 17
TT - Trinidad e Tobago 17
SV - El Salvador 16
UZ - Uzbekistan 16
PR - Porto Rico 15
CI - Costa d'Avorio 14
GT - Guatemala 14
KE - Kenya 14
AT - Austria 13
JM - Giamaica 13
CW - ???statistics.table.value.countryCode.CW??? 12
JO - Giordania 12
NI - Nicaragua 12
PY - Paraguay 12
KR - Corea 10
BO - Bolivia 9
IR - Iran 9
TN - Tunisia 9
CZ - Repubblica Ceca 8
GP - Guadalupe 8
KZ - Kazakistan 8
AE - Emirati Arabi Uniti 7
AZ - Azerbaigian 7
BG - Bulgaria 7
BH - Bahrain 7
OM - Oman 7
NP - Nepal 6
UY - Uruguay 6
EG - Egitto 5
ET - Etiopia 5
HU - Ungheria 5
SC - Seychelles 5
TH - Thailandia 5
CH - Svizzera 4
DZ - Algeria 4
EE - Estonia 4
LB - Libano 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
RS - Serbia 4
AL - Albania 3
GE - Georgia 3
HR - Croazia 3
PS - Palestinian Territory 3
PT - Portogallo 3
QA - Qatar 3
RO - Romania 3
SN - Senegal 3
SY - Repubblica araba siriana 3
AM - Armenia 2
BB - Barbados 2
BY - Bielorussia 2
CM - Camerun 2
DK - Danimarca 2
EU - Europa 2
KN - Saint Kitts e Nevis 2
LC - Santa Lucia 2
LY - Libia 2
Totale 19.220
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Città #
Ashburn 1.061
Fairfield 983
San Jose 765
Singapore 761
Chandler 714
Jacksonville 676
Woodbridge 581
Hong Kong 517
Houston 457
Milan 428
Seattle 400
Cambridge 382
Wilmington 329
Nyköping 310
Council Bluffs 290
Ann Arbor 233
Beijing 209
Nanjing 195
Lawrence 163
New York 163
Roxbury 160
Helsinki 149
Lauterbourg 145
Rome 143
Boardman 132
Bari 115
Des Moines 106
Dallas 104
Los Angeles 100
Santa Clara 93
São Paulo 85
Princeton 75
Ho Chi Minh City 70
Washington 65
Columbus 64
Nanchang 62
Figino 60
Brooklyn 58
Hanoi 55
San Diego 43
Buffalo 41
Turin 39
London 36
Rio de Janeiro 36
Chicago 35
Shenyang 35
Inglewood 34
San Francisco 34
Dublin 30
Jakarta 30
Hebei 29
Montreal 28
Phoenix 28
Toronto 28
Jiaxing 26
Naples 26
Dearborn 25
Munich 24
Baghdad 23
Changsha 23
Paris 23
Tianjin 23
Moscow 22
Warsaw 21
Atlanta 20
Guangzhou 20
Brussels 19
Orem 19
Amsterdam 18
Johannesburg 18
Quito 18
San José 18
Denver 17
Kunming 17
Mexico City 17
Molfetta 17
Nuremberg 17
Shanghai 17
Bologna 16
Palermo 16
Tokyo 16
Boston 15
Brasília 15
Charlotte 15
Frankfurt am Main 15
Abidjan 14
Belo Horizonte 14
Zhengzhou 14
Guatemala City 13
Melbourne 13
North Bergen 13
Tashkent 13
Wuhan 13
Chennai 12
Guayaquil 12
Managua 12
Porto Alegre 12
Vilnius 12
Willemstad 12
Amman 11
Totale 12.750
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Nome #
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 234
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 210
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 205
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 203
Insights into the role of the lead/surfactant ratio in the formation and passivation of cesium lead bromide perovskite nanocrystals 202
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 190
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 186
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 185
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 182
Method of treating colorectal cancer. 175
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 173
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 165
DNA fragment conformations in adducts with Kiteplatin 162
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 162
First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer 161
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 161
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 159
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 157
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 156
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 152
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 150
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 150
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 150
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 148
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 146
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum-bisphosphonate complexes in the treatment of bone tumors: A mini-review 144
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity 144
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy 144
Activation of antitumoral platinum prodrugs for the local treatment of bone tumors by inclusion in bioactive inorganic matrices. 143
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 143
Novel Therapeutic Agents for Bone Resorption. Part 1. Synthesis and Protonation Thermodynamics of Poly(amido-amine)s Containing Bis-phosphonate Residues 142
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 139
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 138
PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study 138
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 137
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 136
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 136
Unusual DNA Binding Properties of Chelate Ring-opening Platinum Complexes 135
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 135
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 133
Antitumor trans iminoether platinum di- and oligonucleotide adducts studied by NMR. 131
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 131
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 130
Back to the future with Kiteplatin: an efficacious drug against oxaliplatin-refractory colorectal cancer. 129
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 128
Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug 128
9[(aminoalkyl)amino]nitroacridines: kinetic vs thermodynamic interactions towards platinum(II) and factors ruling their tautomeric equilibrium. 126
Dinuclear Pt(II)-bisphosphonates complexes: useful precursors of multinuclear or higher oxidation state platinum drugs. 126
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 126
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring 126
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 125
Monofunctional platinum(II) complexes and moleules of biological relevance: evaluation of steric and electronic factors in the competition for binding sites. 124
Computational evidence for structural consequences of kiteplatin damage on DNA 124
Assessing inter-nucleot(s)ide interactions by conformational studies of adducts between platinum complexes with carrier ligand unable to form H-bonds and guanine derivatives. 123
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds. 123
A novel Platinum(II) complex tethered to a ligand having high affinity for the Peripheral Benzodiazepine Receptor 123
A new synthetic approach for size-tunable and stable CsPbBr3 nanocubes with near-unity photoluminescence quantum yield 122
Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model 121
Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)] 119
Strong, Rapid Binding of a Platinum Complex to Thymine and Uracil Under Physiological Conditions 119
Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals 119
The influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand 117
Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. 117
Mono- and bis-guanosine adducts of platinum complexes with carrier ligands having in-plane steric bulk: The case of 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline 116
Esercizi risolti (e non) di stechiometria 116
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases 112
Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration 111
NMR investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives. 111
Bioactive Inorganic Matrices for the Local Delivery of Platinum-based Prodrugs in the Treatment of Bone Tumors 109
Dinuclear Pt(II)-bisphosphonate complexes:useful building blocks for the preparation of multinuclear or higher oxidation state platinum drugs. 108
TSPO-seeking Pt(II)- and Pt(IV)-complexes 108
Structure and dynamics of a Platinum(II) aminophosphine complex and its nucleobase adducts 108
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma 107
Antitumor drugs delivery by bone substitute biomimetic hydroxyapatite nanocrystals. 107
Platinum(II) Complexes with Bioactive Carrier Ligands Having High Affinity for the Translocator Protein 106
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug 106
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer. 105
Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin 104
Platinum-Based Antitumor Drugs Containing Enantiomerically Pure alpha-Trifluoromethyl Alanine as Ligand 103
Platinum–bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis 103
H-Bond interactions between the NH of carrier ligand (Me3dien) and the O6 or the 5'-phosphate of guanine nucleotides in platinum complexes with a single guanine ligand. 102
Platinum(II) Complexes with Antitumoral/Antiviral Aromatic Heterocycles: Effect of Glutathione upon in Vitro Cell Growth Inhibition 101
Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells 101
Conformational study on the five member chelate ring of new platinum complexes containing diethyl (methylsulfinyl)methylphosphonate as carrier ligand for bone tumors. 100
Recent findings in the chemistry of five-coordinate platinum(II) alkyne complexes. 100
Drug Targeting and Delivering: Synthesis and NMR Characterization of Potential Antitumor Platinum(II) Complexes alfa-Trifluoromethyl Derivatives of Aminoacids. 99
Synthesis, characterization, and biological activity of novel platinum-based antitumor drugs containing enantiomerically pure alfa-trifluoroethyl alanine as ligand. 97
Molecular insights into growth and time evolution of surface states of CsPbBr3 nanoparticles synthesized by scalable room temperature approach 96
Calcium-modulated release of active platinum antitumor compounds from sol-gel silica xerogels. 94
New platinum-based antitumor drugs containing enantiomerically pure alfa-trifluoromethyl alanine as ligand. 92
New Pt and Re complexes targeting the Translocator Protein 18 kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents 92
Synthesis, characterization, and biological activity of platinum(II) complexes with bioactive carrier ligands having high affinity for the Translocator Protein (TSPO) 91
Synthesis, characterization, and binding to the translocator protein (18 kDa, TSPO) of a new rhenium complex as a model of radiopharmaceutical agents. 91
Conformational study on the five member chelate ring of new platinum complexes containing diethyl[{(methylsulfinyl)methyl}phosphonate carrier ligand for bone tumors. 90
Implementation of Sustainable Solvents in Green Polymerization Approaches 90
New oxaliplatin-zoledronate derivatives with potential antitumor activity towards bone tumors and metastases 90
Drug Targeting and Delivery of Platinum Chemotherapeutics ☆ 89
Bone tumor–targeted delivery of theranostic 195mPt-bisphosphonate complexes promotes killing of metastatic tumor cells 89
In Situ Formation of Zwitterionic Ligands: Changing the Passivation Paradigms of CsPbBr3 Nanocrystals 88
New Pt and Re complexes targeting the Translocator Protein 18kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents. 88
Totale 12.988
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Categoria #
all - tutte 79.654
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.654
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022954 0 0 0 0 48 66 44 57 90 79 188 382
2022/20231.812 297 163 94 176 249 236 23 188 297 23 41 25
2023/2024573 58 107 26 53 77 140 15 5 15 12 4 61
2024/20252.618 95 39 220 83 105 174 240 204 104 171 367 816
2025/20265.677 705 260 330 640 527 330 639 166 603 473 223 781
2026/20272.117 186 415 522 937 57 0 0 0 0 0 0 0
Totale 19.601