IRIS
MARGIOTTA, NICOLA
 Distribuzione geografica
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Continente #
NA - Nord America 8.998
AS - Asia 3.775
EU - Europa 3.269
SA - Sud America 1.090
AF - Africa 137
OC - Oceania 29
Continente sconosciuto - Info sul continente non disponibili 3
Totale 17.301
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Nazione #
US - Stati Uniti d'America 8.854
SG - Singapore 1.514
IT - Italia 1.090
CN - Cina 960
BR - Brasile 871
HK - Hong Kong 524
SE - Svezia 401
RU - Federazione Russa 335
FI - Finlandia 299
UA - Ucraina 291
DE - Germania 283
VN - Vietnam 210
FR - Francia 204
GB - Regno Unito 149
IN - India 111
BD - Bangladesh 88
AR - Argentina 72
CA - Canada 66
ID - Indonesia 50
TR - Turchia 47
IQ - Iraq 44
MX - Messico 44
ZA - Sudafrica 43
EC - Ecuador 37
NL - Olanda 35
CO - Colombia 33
IE - Irlanda 32
VE - Venezuela 31
ES - Italia 30
MA - Marocco 30
PK - Pakistan 30
SA - Arabia Saudita 27
AU - Australia 24
PL - Polonia 24
JP - Giappone 20
BE - Belgio 19
CL - Cile 18
PH - Filippine 16
UZ - Uzbekistan 16
CI - Costa d'Avorio 14
KE - Kenya 14
MY - Malesia 14
AT - Austria 13
JO - Giordania 12
PY - Paraguay 12
KR - Corea 10
LT - Lituania 10
IR - Iran 9
TN - Tunisia 9
BO - Bolivia 8
CZ - Repubblica Ceca 8
AE - Emirati Arabi Uniti 7
AZ - Azerbaigian 7
BG - Bulgaria 7
BH - Bahrain 7
KZ - Kazakistan 7
OM - Oman 7
CR - Costa Rica 6
JM - Giamaica 6
NP - Nepal 6
EG - Egitto 5
ET - Etiopia 5
HU - Ungheria 5
TT - Trinidad e Tobago 5
UY - Uruguay 5
CH - Svizzera 4
DZ - Algeria 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
RS - Serbia 4
AL - Albania 3
GE - Georgia 3
GT - Guatemala 3
HN - Honduras 3
IL - Israele 3
LB - Libano 3
PS - Palestinian Territory 3
PT - Portogallo 3
QA - Qatar 3
RO - Romania 3
SN - Senegal 3
SY - Repubblica araba siriana 3
TH - Thailandia 3
BY - Bielorussia 2
CM - Camerun 2
EE - Estonia 2
EU - Europa 2
HR - Croazia 2
MD - Moldavia 2
NI - Nicaragua 2
PA - Panama 2
PR - Porto Rico 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
BB - Barbados 1
BN - Brunei Darussalam 1
BZ - Belize 1
CY - Cipro 1
Totale 17.278
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Città #
Fairfield 983
Ashburn 812
Singapore 756
Chandler 714
Jacksonville 674
Woodbridge 581
Hong Kong 517
San Jose 515
Houston 455
Milan 424
Seattle 396
Cambridge 382
Wilmington 328
Nyköping 310
Ann Arbor 233
Beijing 205
Nanjing 195
Lawrence 163
Roxbury 160
Helsinki 149
New York 149
Lauterbourg 145
Rome 133
Boardman 131
Bari 109
Des Moines 106
Dallas 87
Los Angeles 82
São Paulo 79
Princeton 74
Ho Chi Minh City 69
Santa Clara 63
Nanchang 62
Columbus 60
Figino 60
Brooklyn 56
Hanoi 55
San Diego 43
Council Bluffs 42
Buffalo 37
Rio de Janeiro 36
London 35
Shenyang 35
Inglewood 34
Dublin 30
Jakarta 30
Hebei 29
Turin 29
Jiaxing 26
Chicago 25
Dearborn 25
San Francisco 25
Munich 24
Baghdad 23
Changsha 23
Paris 23
Tianjin 23
Moscow 22
Montreal 21
Warsaw 21
Guangzhou 20
Brussels 19
Amsterdam 18
Johannesburg 18
Orem 18
Quito 18
Toronto 18
Kunming 17
Mexico City 17
Denver 16
Shanghai 16
Tokyo 16
Brasília 15
Frankfurt am Main 15
Molfetta 15
Nuremberg 15
Phoenix 15
Abidjan 14
Belo Horizonte 14
Boston 14
Naples 14
Zhengzhou 14
Atlanta 13
Melbourne 13
Tashkent 13
Wuhan 13
Chennai 12
Porto Alegre 12
Amman 11
Ankara 11
Auburn Hills 11
Bologna 11
Curitiba 11
Jinan 11
Mumbai 11
Nairobi 11
Turku 11
Washington 11
Casablanca 10
Charlotte 10
Totale 11.695
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Nome #
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 216
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 197
Insights into the role of the lead/surfactant ratio in the formation and passivation of cesium lead bromide perovskite nanocrystals 192
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 188
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 188
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 183
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 179
Method of treating colorectal cancer. 168
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 168
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 166
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 163
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 156
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 154
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 154
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 151
DNA fragment conformations in adducts with Kiteplatin 150
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 144
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 143
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 140
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 140
First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer 137
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 137
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 137
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 137
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 136
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum-bisphosphonate complexes in the treatment of bone tumors: A mini-review 135
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 134
Activation of antitumoral platinum prodrugs for the local treatment of bone tumors by inclusion in bioactive inorganic matrices. 133
Novel Therapeutic Agents for Bone Resorption. Part 1. Synthesis and Protonation Thermodynamics of Poly(amido-amine)s Containing Bis-phosphonate Residues 132
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 131
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 130
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 130
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 129
Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity 129
Selenium-doped hydroxyapatite nanoparticles for potential application in bone tumor therapy 129
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 128
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 126
Unusual DNA Binding Properties of Chelate Ring-opening Platinum Complexes 125
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 124
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 123
Antitumor trans iminoether platinum di- and oligonucleotide adducts studied by NMR. 123
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 122
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 121
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 120
PEGylated solid lipid nanoparticles for brain delivery of lipophilic kiteplatin Pt(IV) prodrugs: An in vitro study 120
Dinuclear Pt(II)-bisphosphonates complexes: useful precursors of multinuclear or higher oxidation state platinum drugs. 119
Back to the future with Kiteplatin: an efficacious drug against oxaliplatin-refractory colorectal cancer. 118
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 118
9[(aminoalkyl)amino]nitroacridines: kinetic vs thermodynamic interactions towards platinum(II) and factors ruling their tautomeric equilibrium. 117
Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug 117
Computational evidence for structural consequences of kiteplatin damage on DNA 117
Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)] 116
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds. 115
A novel Platinum(II) complex tethered to a ligand having high affinity for the Peripheral Benzodiazepine Receptor 115
Strong, Rapid Binding of a Platinum Complex to Thymine and Uracil Under Physiological Conditions 114
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring 114
Assessing inter-nucleot(s)ide interactions by conformational studies of adducts between platinum complexes with carrier ligand unable to form H-bonds and guanine derivatives. 113
Mono- and bis-guanosine adducts of platinum complexes with carrier ligands having in-plane steric bulk: The case of 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline 112
Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals 112
Preclinical evaluation of platinum-loaded hydroxyapatite nanoparticles in an embryonic zebrafish xenograft model 112
A new synthetic approach for size-tunable and stable CsPbBr3 nanocubes with near-unity photoluminescence quantum yield 107
NMR investigation of the Spontaneous Thermal- and/or Photoinduced Reduction of trans Dihydroxido Pt(IV) Derivatives. 107
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases 106
Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. 103
Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration 102
Platinum(II) Complexes with Bioactive Carrier Ligands Having High Affinity for the Translocator Protein 102
The influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand 102
TSPO-seeking Pt(II)- and Pt(IV)-complexes 101
Structure and dynamics of a Platinum(II) aminophosphine complex and its nucleobase adducts 101
Metallo-drugs in the Treatment of Malignant Pleural Mesothelioma 99
Bioactive Inorganic Matrices for the Local Delivery of Platinum-based Prodrugs in the Treatment of Bone Tumors 98
Dinuclear Pt(II)-bisphosphonate complexes:useful building blocks for the preparation of multinuclear or higher oxidation state platinum drugs. 97
Platinum–bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis 97
Platinum(II) Complexes with Antitumoral/Antiviral Aromatic Heterocycles: Effect of Glutathione upon in Vitro Cell Growth Inhibition 96
Antitumor drugs delivery by bone substitute biomimetic hydroxyapatite nanocrystals. 96
Revisiting [PtCl2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer. 95
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug 93
Recent findings in the chemistry of five-coordinate platinum(II) alkyne complexes. 92
Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin 92
Platinum-Based Antitumor Drugs Containing Enantiomerically Pure alpha-Trifluoromethyl Alanine as Ligand 91
H-Bond interactions between the NH of carrier ligand (Me3dien) and the O6 or the 5'-phosphate of guanine nucleotides in platinum complexes with a single guanine ligand. 89
Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells 89
null 88
Monofunctional platinum(II) complexes and moleules of biological relevance: evaluation of steric and electronic factors in the competition for binding sites. 86
Drug Targeting and Delivery of Platinum Chemotherapeutics ☆ 85
Calcium-modulated release of active platinum antitumor compounds from sol-gel silica xerogels. 84
Conformational study on the five member chelate ring of new platinum complexes containing diethyl (methylsulfinyl)methylphosphonate as carrier ligand for bone tumors. 83
New Pt and Re complexes targeting the Translocator Protein 18 kDa (TSPO) as potential chemotherapics, radiopharmaceuticals, or theranostic agents 83
Synthesis, characterization, and binding to the translocator protein (18 kDa, TSPO) of a new rhenium complex as a model of radiopharmaceutical agents. 83
Implementation of Sustainable Solvents in Green Polymerization Approaches 83
Molecular insights into growth and time evolution of surface states of CsPbBr3 nanoparticles synthesized by scalable room temperature approach 81
Inclusion of Antitumoral platinum drugs in bioactive inorganic matrices to be used for the local treatment of bone tumors. 81
Bone tumor–targeted delivery of theranostic 195mPt-bisphosphonate complexes promotes killing of metastatic tumor cells 81
Synthesis, characterization, and biological activity of platinum(II) complexes with bioactive carrier ligands having high affinity for the Translocator Protein (TSPO) 80
In vitro targeting and imaging the Translocator Protein TSPO 18-kDa through new coordination complexes of transition metals. 80
Conformational study on the five member chelate ring of new platinum complexes containing diethyl[{(methylsulfinyl)methyl}phosphonate carrier ligand for bone tumors. 79
null 79
Targeting of Pt(II)- and Pt(IV)-complexes to TSPO. 78
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective metal-chelating ligand 78
null 78
Totale 11.922
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Categoria #
all - tutte 72.858
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.858
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.185 36 175 11 9 48 66 44 57 90 79 188 382
2022/20231.812 297 163 94 176 249 236 23 188 297 23 41 25
2023/2024573 58 107 26 53 77 140 15 5 15 12 4 61
2024/20252.618 95 39 220 83 105 174 240 204 104 171 367 816
2025/20265.677 705 260 330 640 527 330 639 166 603 473 223 781
2026/2027162 162 0 0 0 0 0 0 0 0 0 0 0
Totale 17.646