IRIS
INTINI, Francesco Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 4.542
EU - Europa 900
AS - Asia 634
SA - Sud America 3
OC - Oceania 2
AF - Africa 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.083
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Nazione #
US - Stati Uniti d'America 4.535
CN - Cina 455
SE - Svezia 328
UA - Ucraina 142
SG - Singapore 133
IT - Italia 117
FI - Finlandia 107
DE - Germania 98
GB - Regno Unito 46
IN - India 29
BE - Belgio 16
IE - Irlanda 12
IR - Iran 10
FR - Francia 9
CA - Canada 7
CZ - Repubblica Ceca 7
RU - Federazione Russa 7
NL - Olanda 3
AT - Austria 2
SA - Arabia Saudita 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AU - Australia 1
CL - Cile 1
EC - Ecuador 1
GR - Grecia 1
JP - Giappone 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PL - Polonia 1
PT - Portogallo 1
RO - Romania 1
ZA - Sudafrica 1
Totale 6.083
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Città #
Fairfield 696
Woodbridge 460
Chandler 440
Jacksonville 314
Ashburn 305
Houston 286
Seattle 280
Nyköping 276
Cambridge 236
Wilmington 210
Ann Arbor 156
Nanjing 128
Singapore 97
Lawrence 92
Roxbury 92
New York 88
Boardman 87
Princeton 70
Des Moines 62
Bari 53
Beijing 53
Nanchang 51
Inglewood 39
Brooklyn 30
San Diego 28
Helsinki 27
Jiaxing 26
Dearborn 25
Shenyang 24
Pune 20
Hebei 18
San Mateo 17
Santa Clara 17
Brussels 16
Tianjin 16
Changsha 14
Kunming 14
Jinan 12
Leawood 12
Molfetta 11
Dublin 10
Guangzhou 10
Ardabil 9
Los Angeles 9
Noicattaro 9
Monmouth Junction 8
Shanghai 7
Brno 6
Lanzhou 6
London 6
Augusta 5
Mumbai 5
Paris 5
Taizhou 5
Washington 5
Marseille 4
Norwalk 4
Toronto 4
Wuhan 4
Zhengzhou 4
Adelfia 3
Birmingham 3
Munich 3
San Francisco 3
Shaoxing 3
Changchun 2
Fuzhou 2
Hangzhou 2
Hefei 2
Jinhua 2
Ningbo 2
Ottawa 2
Quanzhou 2
Riyadh 2
Tangshan 2
Amsterdam 1
Auburn Hills 1
Auckland 1
Baotou 1
Bilgi 1
Callao 1
Casapesenna 1
Cerano 1
Chicago 1
Chiswick 1
Chizhou 1
Chongqing 1
Clearwater 1
Clifton 1
Cupertino 1
Dallas 1
Delhi 1
Dongyang 1
Edinburgh 1
Falls Church 1
Foshan 1
Gioia del Colle 1
Guiyang 1
Hounslow 1
Hunedoara 1
Totale 5.083
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Nome #
Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage 158
Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1‑Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses 138
Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects 122
Lantern-Shaped” Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt2{HN=C(But)O}4L2](NO3)2 113
Addition of Hydroxide, Alkoxide, and Carboxylate Anions to Platinum-bonded Ethylene 111
null 104
Isomerism of amides coordinated to platinum. X-ray crystal structure of dichloro-bisacetamide-platinum(II) 104
Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent 99
Single-Stranded Oligonucleotide Adducts Formed by Pt Complexes Favoring Left-Handed Base Canting: Steric Effect of Flanking Residues and Relevance to DNA Adducts Formed by Pt Anticancer Drugs 98
Cytotoxic trans-oriented platinum complexes only form adducts with single-stranded oligodeoxynucleotides 95
Atropisomerization of cis-Bis(5'GMP)-Platinum(II)-Diamine complexes with Non-C2-symmetrical asymmetric diamine ligands containing NH groups directed to one side of the coordination plane 94
The First Example of a Dinuclear Platinum(III) Complex with Three Bridging Ligands 93
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 93
Potentiation of cytotoxic action of cis-[PtCl2(NH3)(1M7AI)] by UVA irradiation. Mechanistic insights 93
Insights into the Molecular Mechanisms of Protein Platination from a Case Study: The Reaction of Anticancer Platinum(II) Iminoethers with Horse Heart Cytochrome c 92
Cytotoxic trans-oriented iminoether platinum complexes – Kinetics of binding to DNA oligonucleotides determined by 15N NMR spectroscopy 92
NMR and X-ray Structural Characterization of a Cisplatin Analogue Able To Slow Down the Pt−N7 Rotation of a Coordinated Guanine Base by a Billion-Fold Times: 2,2'-Bipiperidine(dimethylmalonato)platinum(II) Complex 91
NMR and X-ray characterization of a platinum(II) complex with (−)sparteine 91
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 91
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 91
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine 90
Platinum amides from platinum nitriles: X-ray crystal structure of trans-dichloro-bis(1-imino-1-hydroxy-2,2-dimethylpropane)platinum(II) 90
null 89
null 88
Unusual reactivity at a platinum center determined by the ligands and the solvent environment 82
Synthesis and structural characterization of isomeric "lantern-shaped" platinum(III) complexes of formula [Pt2(PPh3)X{N(H)C(R)O}4](NO3)2 (X=PPh3, H2O) 82
Solution Behavior of Amidine Complexes: An Unexpected cis/trans Isomerization and Formation of Di- and Trinuclear Platinum(III) and Platinum(II) Species 80
Solvolysis of Platinum Complexes with Substituted Ethylenediamines in Dimethylsulfoxide 80
null 80
A novel head-to-head conformer of d(GpG) cross-linked by Pt: New light on the conformation of such cross-links formed by Pt anticancer drugs 79
Synthesis and in vitro antitumor activity of platinum acetonimine complexes 75
Bis[iodo(N,N,N′,N'',N''-pentamethyldiethyl-enetriamine- kappa N-3)platinum(II)] di-μ-iodobis[diiodoplatinate(II)] 74
Factors Influencing the Configuration and Conformation of Diamine Chelate Rings in Platinum(II) Compounds: 2,4- Bis(methylamino)pentane Complexes 74
Effects of six-membered-ring conformation on the rotamer distribution and rate of atropisomerization in platinum(II)-guanine compounds: 2,4-bis(methylamino)pentane complexes 74
Processo di sintesi di complessi di platino con imminoeteri e loro utilizzazione come agenti antitumorali e agenti modificanti le basi nucleotidiche 74
ANTIBACTERIAL AND ANTICANCER ACTIVITY OF PLATINUM COMPLEXES WITH CHIRAL DIAMINES 72
Synthesis and X-ray crystal structure of a trans-dichloro(1-cyano-2,2-dimethylpropane)(1-imino-1-hydroxy-2,2-dimethylpropane)platinum(II) 72
Biological Activity of Platinum Complexes Containing Chiral Centers on the Nitrogen or Carbon atoms of a Chelate Diamine Ring. Inorg. Chim. Acta, 71
Chirality-Controlling Chelate (CCC) Ligands in Analogs of Platinum Anticancer Agents. Influence of N9 Substituents of Guanine Derivatives (G) on the Distribution of Chiral Conformers of (CCC)PtG2 with CCC = N,N'-Dimethyl-2,3-diaminobutane 71
New steric hindrance approach employing the hybrid ligand 2-aminomethylpiperidine for diminishing dynamic motion problems of platinum anticancer drug adducts containing guanine derivatives 70
Structural characterization of the “lantern-shaped” platinum(III) complex [Pt2Cl2{N(H)C(But)O}4] 69
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 68
null 67
null 66
Isolation, Characterization, and Kinetics of Formation of the cis and trans Isomers of Bis(acetonitrile)dichloroplatinum(II) 66
Platinum(II) complexes with the purine derivatives Penciclovir and Famciclovir; monoadducts with potential antitumor and antiviral activity 63
Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+ 63
Synthesis, characterization, and biological activity of platinum II, III, and IV pivaloamidine complexes 63
Synthesis and spectroscopic and structural characterization of different configurations of the tridentate amine ligand N,N’,N’’-trimethyldiethylenetriamine coordinated to platinum 62
DIFFERENT BINDING TO DNA OF ENANTIOMERIC PLATINUM COMPLEXES ASSESSED BY INHIBITION OF RESTRICTION ENZYME-ACTIVITY 61
IRREVERSIBLE ADDITION OF CARBON NUCLEOPHILES TO ETHYLENE IN CATIONIC PLATINUM(II) COMPLEXES 61
trans-Chloridobis[(Z)-1-imino-1-methoxyethane-N](triphenylphosphane-P)platinum(II) chloride monohydrate 61
Iminoethers as Carrier Ligands: A Novel trans-Platinum Complex Possessing in Vitro and in Vivo Antitumour Activity 60
null 58
Retro-Models of Pt Anticancer Drug DNA Adducts: Chirality-Controlling Chelate (CCC) Ligand Restriction of Guanine Dynamic Motion in (2,2'-Bipiperidine)PtG2 Complexes (G = Guanine Derivative) 57
Stereochemical Investigations of Cationic Olefin Complexes of Platinum(II) Containing Chiral Diamines: a Sequence of Four Asymmetric Centres (N, C, C and N) in the chelate ring 57
Synthesis and X-Ray Structural Characterization of the First Unbridged Diplatinum(III) Compound: Bis[bis(1-imino-1-hydroxy-2,2-dimethyl-propane)-trichloroplatinum(III)] 57
Diminishing Dynamic Motion Problems of Platinum Anticancer Drug Adducts of Guanine Derivatives with the Hybrid Ligand Approach: Evidence for Cis Interligand Interactions Especially between 3'-GMP's 57
X-ray Structural Characterization of the Bis-Guanine Derivative of a Cisplatin Analogue Having Just One Proton on Each Coordinated Nitrogen and a Head-to-Head Conformation: [Pt{(±)-N,N'-dimethylbutane-2,3-diamine}(9-ethyl-guanine)2]dinitrate 57
NUCLEOPHILIC-ATTACK OF METHANOL ON BIS(BENZONITRILE)DICHLOROPLATINUM - FORMATION OF MONO-IMIDO AND BIS-IMIDO ESTER DERIVATIVES 57
null 55
Sinthesis and stereochemical characterisation of platinum(II) complexes with the antiviral agents penciclovir and famciclovir 54
Retro-modeling in Pt anticancer drug chemistry 53
Platinum Amides from Platinum Nitriles: X-ray Crystal Structures of the Unbridged Dinuclear Compounds Bis[bis(1-imino-1-hydroxy-2,2-dimethylpropane)dichloro-platinum(II)] and Bis[bis(1-imino-1-hydroxy-2,2-dimethylpropane)(1-amino-1-oxo-2,2-dimethylpropane)dichloro-platinum(II)] 53
null 52
Synthesis and Crystal Structure of a Trans-Diaquabis(amidato) Complex of Platinum(II) 48
Sinthesis and characterisation of the amidine complexes trans-[PtCl(NH3)(HN=C(NH2)R)2]Cl (R= Me,Ph,CH2Ph) derived from addition of NH3 to the coordinated nitriles in trans-[PtCl2(NCR)2] 46
Comparison of cytotoxicity, cellular accumulation and cell cycle modifications of cisplatin and trans-[PtCl2E(iminoether)2] in human and ovarian carcinoma cell lines 45
DNA adducts of antitumor trans-[PtCl2(E-imimo ether)2] 42
Biochemical aspects of antitumor effects of a new platinum(IV) drug 42
Complessi antitumorali di platino a geometria trans 40
MECHANISTIC AND STEREOCHEMICAL INVESTIGATION OF IMINO ETHERS FORMED BY ALCOHOLYSIS OF COORDINATED NITRILES - X-RAY CRYSTAL-STRUCTURES OF CIS-BIS(1-IMINO-1-METHOXYETHANE)DICHLOROPLATINUM(II) AND TRANS-BIS(1-IMINO-1-METHOXYETHANE)DICHLOROPLATINUM(II) 36
Synthesis and Crystal Structure of the First Trinuclear Chloride-bridged Platinum(II) Complex with Mutually Perpendicular Co-ordination Planes: cyclo-Tri-mu-chloro-tris[chloro(1-hydroxy-1-imino-2,2-dimethylpropane)platinum(II)]-Dichloromethane (0.5/1) 35
Cytotoxicity and DNA binding mode of new platinum iminoether derivatives with different configuration at the iminoether ligands 34
null 33
Mechanistic studies on platinum(II) complexes with iminoethers: a trans platinum antitumor agent. 33
SYNTHESIS, MUTAGENICITY, BINDING TO PBR-322 DNA AND ANTITUMOR-ACTIVITY OF PLATINUM(II) COMPLEXES WITH ETHAMBUTOL 33
Nucleophilic Attack of Amine and Hydroxide to Platinum Dibenzonitrile Dichloride. Crystal structure of [Pt(NH=CPhN-t-BuCH2CH2NH-t-Bu)Cl(NHCOPh)] (2) and cis-[Pt(NH=CPhN-t-BuCH2CH2NH-t-Bu)Cl2(NCPh)](3) 33
In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum-iminoether complexes with different configuration at the iminoether ligands 33
X-ray Structure of the first Platinum Complexes with Z Configuration of the Iminoether Ligands: trans Dichlorobis(1-imino-1-methoxy- 2,2'-dimethylpropane)platinum(II) and trans-Tetrachlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(IV) 31
Isomerization of Platinum-Coordinated Iminoethers Induced by Spectator Ligands: Stabilization of the Z anti Configuration 30
Platinum (II) complexes containing iminoethers: a trans platinum antitumour agent 30
Cyclodextrin polymers as carriers for the platinum-based anticancer agent LA-12 30
Isomerism of amides coordinated to platinum - X-ray crystal structure of O-bonded acetamide in a platinum(II) complex 29
Two polymorphs of potassium trichloro[diethyl (methylsulfinylmethyl)phosphonate-kS]platinum(II) with Z' = 1 and 3 in the space group P212121 29
A new generation of platinum anticancer complexes with trans geometry 29
Synthesis and in vitro and in vivo antitumour activity of new platinum-iminoether derivatives with different configuration at the iminoether ligands 29
null 28
Synthesis and X-Ray Characterization of Two Unbridged Diplatinum(III) Compounds: cis and trans-Bis[bis(1-imino-1-methoxyethane)trichloroplatinum(III)]. Transient Species in the Oxidation of Platinum(II) to Platinum(IV) 27
Four- versus Five-coordination in Palladium(II) and Platinum(II) Complexes Containing 2,9-Dimethyl-1,10-phenanthroline (dmphen). Crystal Structures of [PtCl2(dmphen)] and [Pt(h2-C2H4)Cl2(dmphen)] 26
New concepts relevant to cisplatin anticancer activity from unique spectral features providing evidence that adjacent guanines in d(GpG), intrastrand-cross-linked at N7 by a cis-platinum(II) moiety, can adopt a head-to-tail arrangement 24
Kinetic study of the reaction between an antitumor 15N labeled trans- platinum iminoether complex and GMP by [1H,15N] HMQC NMR 22
New platinum antitumor complexes with chiral diamines 21
Viewing early stages of guanine nucleotide attach on Pt(II) complexes designed with in-plane bulk to trap initial adducts. Relevance to cis-Type Pt(II) anticancer drugs 21
A trans-platinum complex showing higher antitumor activity than the cis congeners 20
Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties 20
Cisplatin and zoledronic acid: two drugs combined in a Pt(II) complex with potential antitumor activity towards bone tumors and metastases 19
Stereochemically Controlled Ligands Influence Atropisomerization of Pt(II) Nucleotide Complexes. Evidence for Head-to-Head and Stable a Head-to-Tail Atropisomers 18
Dna interaction properties of new platinum-iminoether derivatives with different configuration at the iminoether ligands 17
Synthesis and characterization of new platinum(II) complexes with cyclic iminoether-type ligands having the azomethine group out of cycle 17
Totale 6.177
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Categoria #
all - tutte 25.665
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.665
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020907 0 0 0 0 0 107 173 145 204 98 142 38
2020/2021928 89 57 102 43 74 44 52 54 95 153 123 42
2021/2022675 13 95 5 31 34 39 28 42 58 61 135 134
2022/20231.209 197 101 79 112 170 166 6 148 179 14 19 18
2023/2024399 31 63 10 33 38 144 2 14 7 4 1 52
2024/2025271 48 31 125 32 20 15 0 0 0 0 0 0
Totale 6.239