IRIS
INTINI, Francesco Paolo
 Distribuzione geografica
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Continente #
NA - Nord America 4.467
EU - Europa 885
AS - Asia 502
OC - Oceania 2
SA - Sud America 2
AF - Africa 1
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.860
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Nazione #
US - Stati Uniti d'America 4.462
CN - Cina 443
SE - Svezia 328
UA - Ucraina 141
IT - Italia 117
FI - Finlandia 101
DE - Germania 97
GB - Regno Unito 45
IN - India 29
BE - Belgio 16
SG - Singapore 14
IE - Irlanda 12
IR - Iran 10
FR - Francia 9
CZ - Repubblica Ceca 7
CA - Canada 5
NL - Olanda 3
AT - Austria 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AU - Australia 1
CL - Cile 1
GR - Grecia 1
JP - Giappone 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PL - Polonia 1
PT - Portogallo 1
RO - Romania 1
RU - Federazione Russa 1
SA - Arabia Saudita 1
ZA - Sudafrica 1
Totale 5.860
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Città #
Fairfield 696
Woodbridge 460
Chandler 440
Jacksonville 314
Ashburn 302
Houston 286
Seattle 280
Nyköping 276
Cambridge 236
Wilmington 210
Ann Arbor 156
Nanjing 128
Lawrence 92
Roxbury 92
New York 88
Boardman 73
Princeton 70
Des Moines 62
Bari 53
Beijing 53
Nanchang 51
Inglewood 39
Brooklyn 30
San Diego 28
Jiaxing 26
Dearborn 25
Shenyang 24
Helsinki 21
Pune 20
Hebei 18
San Mateo 17
Brussels 16
Tianjin 16
Changsha 14
Kunming 14
Jinan 12
Leawood 12
Molfetta 11
Dublin 10
Ardabil 9
Guangzhou 9
Noicattaro 9
Monmouth Junction 8
Singapore 8
Shanghai 7
Brno 6
Lanzhou 6
London 6
Augusta 5
Mumbai 5
Paris 5
Taizhou 5
Washington 5
Los Angeles 4
Marseille 4
Norwalk 4
Toronto 4
Wuhan 4
Adelfia 3
Birmingham 3
San Francisco 3
Shaoxing 3
Zhengzhou 3
Changchun 2
Fuzhou 2
Hangzhou 2
Hefei 2
Jinhua 2
Munich 2
Ningbo 2
Quanzhou 2
Amsterdam 1
Auburn Hills 1
Auckland 1
Baotou 1
Bilgi 1
Callao 1
Casapesenna 1
Cerano 1
Chicago 1
Chiswick 1
Chizhou 1
Chongqing 1
Clearwater 1
Cupertino 1
Dallas 1
Delhi 1
Dongyang 1
Edinburgh 1
Falls Church 1
Gioia del Colle 1
Hounslow 1
Hunedoara 1
Huzhou 1
Lequile 1
Markham 1
Melbourne 1
Milan 1
Modugno 1
Muizenberg 1
Totale 4.944
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Nome #
Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage 154
Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1‑Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses 135
Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects 122
Lantern-Shaped” Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt2{HN=C(But)O}4L2](NO3)2 110
Addition of Hydroxide, Alkoxide, and Carboxylate Anions to Platinum-bonded Ethylene 108
null 104
Isomerism of amides coordinated to platinum. X-ray crystal structure of dichloro-bisacetamide-platinum(II) 99
Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent 98
Single-Stranded Oligonucleotide Adducts Formed by Pt Complexes Favoring Left-Handed Base Canting: Steric Effect of Flanking Residues and Relevance to DNA Adducts Formed by Pt Anticancer Drugs 96
Cytotoxic trans-oriented platinum complexes only form adducts with single-stranded oligodeoxynucleotides 94
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 92
Atropisomerization of cis-Bis(5'GMP)-Platinum(II)-Diamine complexes with Non-C2-symmetrical asymmetric diamine ligands containing NH groups directed to one side of the coordination plane 92
Insights into the Molecular Mechanisms of Protein Platination from a Case Study: The Reaction of Anticancer Platinum(II) Iminoethers with Horse Heart Cytochrome c 91
Cytotoxic trans-oriented iminoether platinum complexes – Kinetics of binding to DNA oligonucleotides determined by 15N NMR spectroscopy 91
Potentiation of cytotoxic action of cis-[PtCl2(NH3)(1M7AI)] by UVA irradiation. Mechanistic insights 90
null 89
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 89
NMR and X-ray Structural Characterization of a Cisplatin Analogue Able To Slow Down the Pt−N7 Rotation of a Coordinated Guanine Base by a Billion-Fold Times: 2,2'-Bipiperidine(dimethylmalonato)platinum(II) Complex 88
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine 88
Platinum amides from platinum nitriles: X-ray crystal structure of trans-dichloro-bis(1-imino-1-hydroxy-2,2-dimethylpropane)platinum(II) 88
null 88
Influence of carrier ligand NH hydrogen bonding to the O6 and phosphate group of Guanine nucleotides in Platinum complexes with a single guanine ligand 88
The First Example of a Dinuclear Platinum(III) Complex with Three Bridging Ligands 87
NMR and X-ray characterization of a platinum(II) complex with (−)sparteine 86
Unusual reactivity at a platinum center determined by the ligands and the solvent environment 80
Synthesis and structural characterization of isomeric "lantern-shaped" platinum(III) complexes of formula [Pt2(PPh3)X{N(H)C(R)O}4](NO3)2 (X=PPh3, H2O) 80
null 80
Solvolysis of Platinum Complexes with Substituted Ethylenediamines in Dimethylsulfoxide 78
Solution Behavior of Amidine Complexes: An Unexpected cis/trans Isomerization and Formation of Di- and Trinuclear Platinum(III) and Platinum(II) Species 77
A novel head-to-head conformer of d(GpG) cross-linked by Pt: New light on the conformation of such cross-links formed by Pt anticancer drugs 76
Synthesis and in vitro antitumor activity of platinum acetonimine complexes 74
Factors Influencing the Configuration and Conformation of Diamine Chelate Rings in Platinum(II) Compounds: 2,4- Bis(methylamino)pentane Complexes 72
Effects of six-membered-ring conformation on the rotamer distribution and rate of atropisomerization in platinum(II)-guanine compounds: 2,4-bis(methylamino)pentane complexes 72
Bis[iodo(N,N,N′,N'',N''-pentamethyldiethyl-enetriamine- kappa N-3)platinum(II)] di-μ-iodobis[diiodoplatinate(II)] 71
Processo di sintesi di complessi di platino con imminoeteri e loro utilizzazione come agenti antitumorali e agenti modificanti le basi nucleotidiche 71
Synthesis and X-ray crystal structure of a trans-dichloro(1-cyano-2,2-dimethylpropane)(1-imino-1-hydroxy-2,2-dimethylpropane)platinum(II) 70
Biological Activity of Platinum Complexes Containing Chiral Centers on the Nitrogen or Carbon atoms of a Chelate Diamine Ring. Inorg. Chim. Acta, 69
New steric hindrance approach employing the hybrid ligand 2-aminomethylpiperidine for diminishing dynamic motion problems of platinum anticancer drug adducts containing guanine derivatives 68
Chirality-Controlling Chelate (CCC) Ligands in Analogs of Platinum Anticancer Agents. Influence of N9 Substituents of Guanine Derivatives (G) on the Distribution of Chiral Conformers of (CCC)PtG2 with CCC = N,N'-Dimethyl-2,3-diaminobutane 68
ANTIBACTERIAL AND ANTICANCER ACTIVITY OF PLATINUM COMPLEXES WITH CHIRAL DIAMINES 67
Structural characterization of the “lantern-shaped” platinum(III) complex [Pt2Cl2{N(H)C(But)O}4] 67
null 67
null 66
Isolation, Characterization, and Kinetics of Formation of the cis and trans Isomers of Bis(acetonitrile)dichloroplatinum(II) 64
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 63
Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+ 61
Synthesis, characterization, and biological activity of platinum II, III, and IV pivaloamidine complexes 61
Platinum(II) complexes with the purine derivatives Penciclovir and Famciclovir; monoadducts with potential antitumor and antiviral activity 60
Synthesis and spectroscopic and structural characterization of different configurations of the tridentate amine ligand N,N’,N’’-trimethyldiethylenetriamine coordinated to platinum 59
IRREVERSIBLE ADDITION OF CARBON NUCLEOPHILES TO ETHYLENE IN CATIONIC PLATINUM(II) COMPLEXES 59
trans-Chloridobis[(Z)-1-imino-1-methoxyethane-N](triphenylphosphane-P)platinum(II) chloride monohydrate 59
Iminoethers as Carrier Ligands: A Novel trans-Platinum Complex Possessing in Vitro and in Vivo Antitumour Activity 59
DIFFERENT BINDING TO DNA OF ENANTIOMERIC PLATINUM COMPLEXES ASSESSED BY INHIBITION OF RESTRICTION ENZYME-ACTIVITY 58
null 58
Stereochemical Investigations of Cationic Olefin Complexes of Platinum(II) Containing Chiral Diamines: a Sequence of Four Asymmetric Centres (N, C, C and N) in the chelate ring 57
Retro-Models of Pt Anticancer Drug DNA Adducts: Chirality-Controlling Chelate (CCC) Ligand Restriction of Guanine Dynamic Motion in (2,2'-Bipiperidine)PtG2 Complexes (G = Guanine Derivative) 56
Synthesis and X-Ray Structural Characterization of the First Unbridged Diplatinum(III) Compound: Bis[bis(1-imino-1-hydroxy-2,2-dimethyl-propane)-trichloroplatinum(III)] 56
Diminishing Dynamic Motion Problems of Platinum Anticancer Drug Adducts of Guanine Derivatives with the Hybrid Ligand Approach: Evidence for Cis Interligand Interactions Especially between 3'-GMP's 56
null 55
NUCLEOPHILIC-ATTACK OF METHANOL ON BIS(BENZONITRILE)DICHLOROPLATINUM - FORMATION OF MONO-IMIDO AND BIS-IMIDO ESTER DERIVATIVES 55
X-ray Structural Characterization of the Bis-Guanine Derivative of a Cisplatin Analogue Having Just One Proton on Each Coordinated Nitrogen and a Head-to-Head Conformation: [Pt{(±)-N,N'-dimethylbutane-2,3-diamine}(9-ethyl-guanine)2]dinitrate 52
null 52
Sinthesis and stereochemical characterisation of platinum(II) complexes with the antiviral agents penciclovir and famciclovir 51
Platinum Amides from Platinum Nitriles: X-ray Crystal Structures of the Unbridged Dinuclear Compounds Bis[bis(1-imino-1-hydroxy-2,2-dimethylpropane)dichloro-platinum(II)] and Bis[bis(1-imino-1-hydroxy-2,2-dimethylpropane)(1-amino-1-oxo-2,2-dimethylpropane)dichloro-platinum(II)] 51
Retro-modeling in Pt anticancer drug chemistry 50
Synthesis and Crystal Structure of a Trans-Diaquabis(amidato) Complex of Platinum(II) 47
Sinthesis and characterisation of the amidine complexes trans-[PtCl(NH3)(HN=C(NH2)R)2]Cl (R= Me,Ph,CH2Ph) derived from addition of NH3 to the coordinated nitriles in trans-[PtCl2(NCR)2] 42
Comparison of cytotoxicity, cellular accumulation and cell cycle modifications of cisplatin and trans-[PtCl2E(iminoether)2] in human and ovarian carcinoma cell lines 41
DNA adducts of antitumor trans-[PtCl2(E-imimo ether)2] 40
Biochemical aspects of antitumor effects of a new platinum(IV) drug 40
Complessi antitumorali di platino a geometria trans 38
MECHANISTIC AND STEREOCHEMICAL INVESTIGATION OF IMINO ETHERS FORMED BY ALCOHOLYSIS OF COORDINATED NITRILES - X-RAY CRYSTAL-STRUCTURES OF CIS-BIS(1-IMINO-1-METHOXYETHANE)DICHLOROPLATINUM(II) AND TRANS-BIS(1-IMINO-1-METHOXYETHANE)DICHLOROPLATINUM(II) 34
null 33
Synthesis and Crystal Structure of the First Trinuclear Chloride-bridged Platinum(II) Complex with Mutually Perpendicular Co-ordination Planes: cyclo-Tri-mu-chloro-tris[chloro(1-hydroxy-1-imino-2,2-dimethylpropane)platinum(II)]-Dichloromethane (0.5/1) 33
Mechanistic studies on platinum(II) complexes with iminoethers: a trans platinum antitumor agent. 32
SYNTHESIS, MUTAGENICITY, BINDING TO PBR-322 DNA AND ANTITUMOR-ACTIVITY OF PLATINUM(II) COMPLEXES WITH ETHAMBUTOL 31
Nucleophilic Attack of Amine and Hydroxide to Platinum Dibenzonitrile Dichloride. Crystal structure of [Pt(NH=CPhN-t-BuCH2CH2NH-t-Bu)Cl(NHCOPh)] (2) and cis-[Pt(NH=CPhN-t-BuCH2CH2NH-t-Bu)Cl2(NCPh)](3) 31
Isomerization of Platinum-Coordinated Iminoethers Induced by Spectator Ligands: Stabilization of the Z anti Configuration 30
Two polymorphs of potassium trichloro[diethyl (methylsulfinylmethyl)phosphonate-kS]platinum(II) with Z' = 1 and 3 in the space group P212121 29
X-ray Structure of the first Platinum Complexes with Z Configuration of the Iminoether Ligands: trans Dichlorobis(1-imino-1-methoxy- 2,2'-dimethylpropane)platinum(II) and trans-Tetrachlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(IV) 29
In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum-iminoether complexes with different configuration at the iminoether ligands 29
Isomerism of amides coordinated to platinum - X-ray crystal structure of O-bonded acetamide in a platinum(II) complex 28
Synthesis and in vitro and in vivo antitumour activity of new platinum-iminoether derivatives with different configuration at the iminoether ligands 28
null 28
Cyclodextrin polymers as carriers for the platinum-based anticancer agent LA-12 28
A new generation of platinum anticancer complexes with trans geometry 26
Cytotoxicity and DNA binding mode of new platinum iminoether derivatives with different configuration at the iminoether ligands 26
Synthesis and X-Ray Characterization of Two Unbridged Diplatinum(III) Compounds: cis and trans-Bis[bis(1-imino-1-methoxyethane)trichloroplatinum(III)]. Transient Species in the Oxidation of Platinum(II) to Platinum(IV) 25
Four- versus Five-coordination in Palladium(II) and Platinum(II) Complexes Containing 2,9-Dimethyl-1,10-phenanthroline (dmphen). Crystal Structures of [PtCl2(dmphen)] and [Pt(h2-C2H4)Cl2(dmphen)] 24
New concepts relevant to cisplatin anticancer activity from unique spectral features providing evidence that adjacent guanines in d(GpG), intrastrand-cross-linked at N7 by a cis-platinum(II) moiety, can adopt a head-to-tail arrangement 23
Platinum (II) complexes containing iminoethers: a trans platinum antitumour agent 22
New platinum antitumor complexes with chiral diamines 20
Viewing early stages of guanine nucleotide attach on Pt(II) complexes designed with in-plane bulk to trap initial adducts. Relevance to cis-Type Pt(II) anticancer drugs 20
Kinetic study of the reaction between an antitumor 15N labeled trans- platinum iminoether complex and GMP by [1H,15N] HMQC NMR 18
Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties 18
Stereochemically Controlled Ligands Influence Atropisomerization of Pt(II) Nucleotide Complexes. Evidence for Head-to-Head and Stable a Head-to-Tail Atropisomers 17
Synthesis and characterization of new platinum(II) complexes with cyclic iminoether-type ligands having the azomethine group out of cycle 17
Dna interaction properties of new platinum-iminoether derivatives with different configuration at the iminoether ligands 16
A trans-platinum complex showing higher antitumor activity than the cis congeners 16
Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration 14
Totale 5.965
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Categoria #
all - tutte 22.429
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.429
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.664 285 84 49 141 198 107 173 145 204 98 142 38
2020/2021928 89 57 102 43 74 44 52 54 95 153 123 42
2021/2022675 13 95 5 31 34 39 28 42 58 61 135 134
2022/20231.209 197 101 79 112 170 166 6 148 179 14 19 18
2023/2024399 31 63 10 33 38 144 2 14 7 4 1 52
2024/202547 47 0 0 0 0 0 0 0 0 0 0 0
Totale 6.015