IRIS
PIEMONTESE, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 4.657
EU - Europa 1.148
AS - Asia 767
OC - Oceania 6
AF - Africa 4
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 6.589
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Nazione #
US - Stati Uniti d'America 4.647
CN - Cina 465
SE - Svezia 332
IT - Italia 291
SG - Singapore 209
FR - Francia 99
GB - Regno Unito 96
DE - Germania 88
UA - Ucraina 88
FI - Finlandia 72
IN - India 27
VN - Vietnam 24
IE - Irlanda 18
BE - Belgio 11
CH - Svizzera 11
PT - Portogallo 11
CA - Canada 10
IR - Iran 10
HK - Hong Kong 8
ES - Italia 7
AU - Australia 5
NL - Olanda 5
KR - Corea 4
PL - Polonia 4
TW - Taiwan 4
CZ - Repubblica Ceca 3
EU - Europa 3
MY - Malesia 3
TH - Thailandia 3
AT - Austria 2
BD - Bangladesh 2
CL - Cile 2
EG - Egitto 2
GR - Grecia 2
IL - Israele 2
JP - Giappone 2
RU - Federazione Russa 2
AR - Argentina 1
BG - Bulgaria 1
BR - Brasile 1
DK - Danimarca 1
EE - Estonia 1
HR - Croazia 1
ID - Indonesia 1
IQ - Iraq 1
KZ - Kazakistan 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
TR - Turchia 1
Totale 6.589
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Città #
Fairfield 609
Chandler 476
Woodbridge 437
Ashburn 386
Houston 320
Cambridge 287
Nyköping 269
Seattle 242
Jacksonville 208
Ann Arbor 202
Wilmington 191
Singapore 153
Roxbury 113
Lawrence 112
Nanjing 88
Beijing 83
Bari 82
Des Moines 68
New York 65
Princeton 62
Inglewood 56
Boardman 50
Jiaxing 32
Hebei 28
Marseille 28
Dong Ket 24
San Diego 23
Santa Clara 21
Shanghai 21
Boydton 20
Guangzhou 20
Brooklyn 19
Dublin 18
Nanchang 18
Munich 15
Redwood City 15
Changsha 14
Milan 14
Paris 14
London 13
Naples 12
Augusta 11
Brussels 11
Lisbon 11
Los Angeles 11
Shenyang 11
Washington 11
Falls Church 10
Salerno 9
Tianjin 9
Wuhan 9
Wuxi 9
Bitonto 8
Dearborn 8
Shenzhen 8
Helsinki 7
Jinhua 7
Kilburn 7
Lausanne 7
Leawood 7
Toronto 7
Hong Kong 6
Rome 6
San Francisco 6
Zhengzhou 6
Ardabil 5
Brindisi 5
Frankfurt am Main 5
Madrid 5
Patna 5
Pune 5
Barry 4
Foggia 4
Hounslow 4
Jinan 4
Kunming 4
San Mateo 4
Taranto 4
Turin 4
West Jordan 4
Alexandria 3
Amsterdam 3
Bhubaneswar 3
Brahmapur 3
Brno 3
Chiswick 3
Cleveland 3
Detroit 3
Edinburgh 3
Florence 3
Hangzhou 3
Nagold 3
Napoli 3
Serdang 3
Simi Valley 3
Ulju-gun 3
Warsaw 3
Alpignano 2
Bilbao 2
Bitetto 2
Totale 5.253
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Nome #
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity 159
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity 135
An efficient synthesis of the optically active isomers of 2H-1,4-benzoxazine derivatives, novel KATP channel modulators 133
Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity 128
Deep eutectic solvents as novel and effective extraction media for quantitative determination of Ochratoxin A in wheat and derived products 124
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of CLC-Kb channels 119
Comparative LC Enantioseparation of Novel PPAR Agonists on Cellulose- and Amylose-Based Chiral Stationary Phases 117
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 116
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 113
Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists 112
Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer′s disease therapy 110
New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge 105
Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks? 102
Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment 101
Reduction of aflatoxins in apricot kernels by electronic and manual color sorting 100
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression 98
Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update 98
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation 98
An innovative approach for the treatment of Alzheimer’s disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions 96
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection 94
An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands 94
ChemInform Abstract: Convenient Synthesis of Some 3-Phenyl-1-benzofuran-2-carboxylic Acid Derivatives as New Potential Inhibitors of CLC-Kb Channels. 91
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 88
Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates 85
Miscele eutettiche come solventi biocompatibili a basso impatto ambientale per l’estrazione e la determinazione di metaboliti secondari fungini in matrici alimentari 84
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction. 84
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 79
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity. 78
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 78
Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases 76
The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs 76
Synthesis, Biological Evaluation, and Molecular Modeling Investigation of Chiral Phenoxyacetic Acid Analogues with PPARalpha and PPARgamma Agonist Activity 75
Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease 75
Design, synthesis, and in vitro evaluation of hydroxybenzimidazole-donepezil analogues as multitarget-directed ligands for the treatment of Alzheimer's disease 74
Effect of gaseous ozone treatments on DON, microbial contaminants and technological parameters of wheat and semolina 73
Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents 68
Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors 68
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor alpha/gamma ligand LT175 67
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 65
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation 63
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 63
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 62
Natural compounds as FAAH inhibitors: preliminary screening and potential developments 60
Aspergillus carbonarius proteases and their possible activity in Ochratoxin A degradation 60
Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors alpha/gamma agonists 57
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Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions 55
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 54
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 54
Climate change effect on ochratoxin A production and gene expression in Aspergillus carbonarius 52
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 52
Exploiting hydroxyphenylbenzimidazol-based hybrids for metal-modulation in potential anti-Alzheimer´s drugs 49
Plant Food Supplements and food coloring agents derived from Vitis vinifera, a new source of human exposure to Ochratoxin A 48
Deep Eutectic Solvents as effective media for the extraction of small molecules from natural sources 48
Natural plant food supplements and food coloring agents derived from Vitis Vinifera: a new source of human exposure to ochratoxin A 47
(contributo in convegno) MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY; CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 47
SINTESI E VALUTAZIONE BIOLOGICA DI DERIVATI SEMI-RIGIDI DELL'ACIDO 2-(4-CLOROFENOSSI)-3-FENIL-PROPANOICO COME BLOCCANTI DEI CANALI AL CLORO VOLTAGGIO-DIPENDENTI CLC-K 47
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 47
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists 46
Processo e impianto per il trattamento di mosti e vini 46
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 46
Mixing Traditional and Innovative Approaches for the Prevention and Treatment of Neurodegenerative and Cardiovascular Diseases: An Overview 45
(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 44
Synthesis and biological activity evaluation of novel diphenylmethane-based ligands for PPARα and PPARγ 40
Ozone treatment as a possible strategy for reductiono of mycotoxins, pesticides and microbial contamination in durum wheat 39
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Synthesis of Chelating Agents Potentially Useful as Markers for Neurodegenerative Diseases Using Deep Eutectic Solvents 38
Synthesis of New Copper and Zinc Chelators with Potential Therapeutic Application in the Neurodegenerative Diseases 38
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 38
Novel small molecules for PPARs modulation and their potential use for treatment of metabolic disorders 38
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Deep Eutectic Solvents as effective media for the synthesis of Donepezil structure-based hybrids with metal-chelating properties 37
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease 37
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Natural scaffolds with potential metal chelating activity for the multi-target therapy of Alzheimer's Disease: a preliminary study 36
AGONISTI DEI RECETTORI NUCLEARI PPARs COME POTENZIALI NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DELLA SINDROME METABOLICA. 36
Food Coloring Agents and Plant Food Supplements Derived from Vitis vinifera: A New Source of Human Exposure to Ochratoxin A 36
Making traditional Italian almond sweets: effects on aflatoxins levels and distribution in final and waste products. 35
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EFFETTI DERIVANTI DALL'INTRODUZIONE DI SOSTITUENTI SUL NUCLEO DIFENILICO DEL COMPOSTO LT175, AGONISTA DUALE DEI RECETTORI NUCLEARI PPARalfa E PPARgamma 34
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 34
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Can foods influence the onset and progress of neurodegenerative diseases? 32
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Determinanti Molecolari della Selettività di Recettori Nucleari: Analisi Chemiometrica e Docking di Agonisti Selettivi di Recettori PPARs 29
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Metal chelators for the multi-target therapy of Alzheimer's Disease: isolation/synthesis and preliminary biological evaluation of new natural and synthetic compounds. 24
Novel dual PPARalpha/gamma Agonists, as hypoglycemic and antidiabetic agents 24
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Totale 6.189
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Categoria #
all - tutte 31.506
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.506
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.182 0 0 0 92 135 85 196 151 193 134 142 54
2020/20211.191 265 65 56 110 52 29 95 74 63 196 101 85
2021/2022802 61 59 18 20 34 52 27 41 40 44 130 276
2022/20231.340 214 122 90 97 146 172 15 161 236 18 42 27
2023/2024628 36 82 35 35 59 147 44 38 27 26 29 70
2024/2025559 180 78 219 82 0 0 0 0 0 0 0 0
Totale 7.182