IRIS
PIEMONTESE, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 6.608
AS - Asia 3.442
EU - Europa 2.358
SA - Sud America 1.052
AF - Africa 159
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 3
Totale 13.632
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Nazione #
US - Stati Uniti d'America 6.490
SG - Singapore 1.298
BR - Brasile 847
CN - Cina 823
IT - Italia 538
HK - Hong Kong 403
SE - Svezia 338
RU - Federazione Russa 326
VN - Vietnam 312
FR - Francia 257
DE - Germania 213
GB - Regno Unito 210
IN - India 160
FI - Finlandia 132
UA - Ucraina 105
BD - Bangladesh 80
ID - Indonesia 75
AR - Argentina 62
CA - Canada 55
IQ - Iraq 44
TR - Turchia 39
EC - Ecuador 38
CO - Colombia 35
AT - Austria 34
ZA - Sudafrica 32
JP - Giappone 29
PL - Polonia 29
CI - Costa d'Avorio 28
ES - Italia 26
MX - Messico 26
IE - Irlanda 23
NL - Olanda 22
MA - Marocco 21
VE - Venezuela 20
BE - Belgio 19
PT - Portogallo 19
EG - Egitto 16
PH - Filippine 16
KE - Kenya 14
MY - Malesia 14
SA - Arabia Saudita 14
CH - Svizzera 13
CL - Cile 13
PE - Perù 13
PY - Paraguay 13
AE - Emirati Arabi Uniti 11
LT - Lituania 11
PK - Pakistan 11
IR - Iran 10
UZ - Uzbekistan 10
AU - Australia 9
JM - Giamaica 9
KR - Corea 9
TN - Tunisia 9
IL - Israele 8
JO - Giordania 8
OM - Oman 8
AZ - Azerbaigian 7
CR - Costa Rica 7
TW - Taiwan 7
AL - Albania 6
DZ - Algeria 6
KZ - Kazakistan 6
NP - Nepal 6
UY - Uruguay 6
CZ - Repubblica Ceca 5
DO - Repubblica Dominicana 5
GA - Gabon 5
LB - Libano 5
SN - Senegal 5
BH - Bahrain 4
BO - Bolivia 4
EE - Estonia 4
ET - Etiopia 4
GR - Grecia 4
MD - Moldavia 4
PA - Panama 4
TH - Thailandia 4
TT - Trinidad e Tobago 4
CY - Cipro 3
DK - Danimarca 3
EU - Europa 3
KW - Kuwait 3
LY - Libia 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
AM - Armenia 2
BG - Bulgaria 2
BY - Bielorussia 2
GT - Guatemala 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
MG - Madagascar 2
PS - Palestinian Territory 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TJ - Tagikistan 2
Totale 13.608
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Città #
Ashburn 757
Singapore 617
Fairfield 609
Chandler 476
Woodbridge 438
Hong Kong 397
San Jose 369
Houston 331
Cambridge 287
Nyköping 269
Seattle 247
Beijing 208
Jacksonville 208
Ann Arbor 202
Wilmington 192
Ho Chi Minh City 124
Dallas 118
Lauterbourg 115
Roxbury 113
Lawrence 112
New York 108
Bari 106
Nanjing 91
Council Bluffs 87
Los Angeles 81
São Paulo 72
Des Moines 68
Helsinki 62
Princeton 62
Hanoi 61
Inglewood 56
Santa Clara 53
Boardman 50
Munich 50
Jakarta 49
Frankfurt am Main 41
Brooklyn 40
Chicago 34
Jiaxing 33
Naples 32
London 31
Moscow 31
Orem 31
Rio de Janeiro 31
Marseille 29
Abidjan 28
Hebei 28
Tokyo 28
Atlanta 27
North Bergen 27
Buffalo 25
Baghdad 24
Chennai 24
Dong Ket 24
Falkenstein 24
Shanghai 24
Belo Horizonte 23
Dublin 23
San Diego 23
San Francisco 23
Warsaw 23
Boydton 21
Fragagnano 21
Guangzhou 21
Poplar 21
Rome 21
Montreal 20
Brasília 19
Brussels 19
Johannesburg 19
Lisbon 19
Milan 19
Nanchang 18
Paris 17
Changsha 16
Denver 16
Basingstoke 15
Dhaka 15
Redwood City 15
Langenzersdorf 14
Manchester 14
Nuremberg 14
Redondo Beach 14
Toronto 14
Amsterdam 13
Boston 13
Haiphong 13
Medellín 13
Quito 13
Augusta 12
Cairo 12
Columbus 12
Washington 12
Campinas 11
Guayaquil 11
Nairobi 11
Shenyang 11
The Dalles 11
Curitiba 10
Da Nang 10
Totale 8.566
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Nome #
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity 224
An efficient synthesis of the optically active isomers of 2H-1,4-benzoxazine derivatives, novel KATP channel modulators 204
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity 203
Deep eutectic solvents as novel and effective extraction media for quantitative determination of Ochratoxin A in wheat and derived products 182
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 181
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 180
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of CLC-Kb channels 180
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 165
An innovative approach for the treatment of Alzheimer’s disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions 158
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 157
Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists 156
Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease 156
Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity 153
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 152
ChemInform Abstract: Convenient Synthesis of Some 3-Phenyl-1-benzofuran-2-carboxylic Acid Derivatives as New Potential Inhibitors of CLC-Kb Channels. 151
Comparative LC Enantioseparation of Novel PPAR Agonists on Cellulose- and Amylose-Based Chiral Stationary Phases 151
An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands 151
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 148
New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge 148
Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer′s disease therapy 148
Reduction of aflatoxins in apricot kernels by electronic and manual color sorting 147
Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors 147
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation 145
Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment 142
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 137
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 137
Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks? 136
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection 133
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 130
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression 128
Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update 128
Design, synthesis, and in vitro evaluation of hydroxybenzimidazole-donepezil analogues as multitarget-directed ligands for the treatment of Alzheimer's disease 127
Miscele eutettiche come solventi biocompatibili a basso impatto ambientale per l’estrazione e la determinazione di metaboliti secondari fungini in matrici alimentari 125
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity. 122
AGONISTI DEI RECETTORI NUCLEARI PPARs COME POTENZIALI NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DELLA SINDROME METABOLICA. 122
(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 122
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 122
(contributo in convegno) MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY; CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 120
Natural plant food supplements and food coloring agents derived from Vitis Vinifera: a new source of human exposure to ochratoxin A 119
Aspergillus carbonarius proteases and their possible activity in Ochratoxin A degradation 119
Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates 118
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 118
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 118
A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties 117
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction. 115
The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs 115
Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases 114
Processo e impianto per il trattamento di mosti e vini 113
Synthesis, Biological Evaluation, and Molecular Modeling Investigation of Chiral Phenoxyacetic Acid Analogues with PPARalpha and PPARgamma Agonist Activity 111
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation 110
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor alpha/gamma ligand LT175 106
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 105
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 105
Exploiting hydroxyphenylbenzimidazol-based hybrids for metal-modulation in potential anti-Alzheimer´s drugs 103
Effect of gaseous ozone treatments on DON, microbial contaminants and technological parameters of wheat and semolina 103
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 100
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 98
Plant Food Supplements and food coloring agents derived from Vitis vinifera, a new source of human exposure to Ochratoxin A 97
Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents 96
Climate change effect on ochratoxin A production and gene expression in Aspergillus carbonarius 96
Natural compounds as FAAH inhibitors: preliminary screening and potential developments 93
Can foods influence the onset and progress of neurodegenerative diseases? 93
Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions 91
Deep Eutectic Solvents as effective media for the extraction of small molecules from natural sources 91
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 90
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists 90
Ozone treatment as a possible strategy for reductiono of mycotoxins, pesticides and microbial contamination in durum wheat 89
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease 89
Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors alpha/gamma agonists 87
Novel Phenothiazine/Donepezil-Like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease 86
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 85
Synthesis of Chelating Agents Potentially Useful as Markers for Neurodegenerative Diseases Using Deep Eutectic Solvents 84
Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates 84
3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate 83
Mixing Traditional and Innovative Approaches for the Prevention and Treatment of Neurodegenerative and Cardiovascular Diseases: An Overview 83
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy 82
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 80
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ 79
Making traditional Italian almond sweets: effects on aflatoxins levels and distribution in final and waste products. 79
Synthesis of New Copper and Zinc Chelators with Potential Therapeutic Application in the Neurodegenerative Diseases 77
Natural scaffolds with potential metal chelating activity for the multi-target therapy of Alzheimer's Disease: a preliminary study 77
Deep Eutectic Solvents as effective media for the synthesis of Donepezil structure-based hybrids with metal-chelating properties 77
SINTESI E VALUTAZIONE BIOLOGICA DI DERIVATI SEMI-RIGIDI DELL'ACIDO 2-(4-CLOROFENOSSI)-3-FENIL-PROPANOICO COME BLOCCANTI DEI CANALI AL CLORO VOLTAGGIO-DIPENDENTI CLC-K 77
Novel small molecules for PPARs modulation and their potential use for treatment of metabolic disorders 76
Food Coloring Agents and Plant Food Supplements Derived from Vitis vinifera: A New Source of Human Exposure to Ochratoxin A 76
Synthesis and biological activity evaluation of novel diphenylmethane-based ligands for PPARα and PPARγ 74
Repurposing Rivastigmine Anti-AD Drug By Aryloxyacetic Hybridization: Biometal Chelation And Potential Increased Anti-Amyloidogenic Ability 72
Multi-Target Approach for the Design of New Compounds Potentially Useful for the Prevention and Treatment of Cardiovascular and/or Neurodegenerative Diseases 71
Multiple causes, multiple targets: FAAH as a centerpiece for therapy of multifactorial pathologies. 69
Discovery of a dual PPARα/γ partial agonist displaying antisteatotic and antidiabetic properties: in silico studies and X-ray structure determination 68
From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs 67
Lentil (Lens culinaria) and its by-products inclusion in livestock nutrition: present insights and emerging trends in rabbit and poultry system 65
Occurrence and characterization of penicillium species isolated from post-harvest apples in lebanon 64
Metal chelators for the multi-target therapy of Alzheimer's Disease: isolation/synthesis and preliminary biological evaluation of new natural and synthetic compounds. 62
Determinanti Molecolari della Selettività di Recettori Nucleari: Analisi Chemiometrica e Docking di Agonisti Selettivi di Recettori PPARs 62
EFFETTI DERIVANTI DALL'INTRODUZIONE DI SOSTITUENTI SUL NUCLEO DIFENILICO DEL COMPOSTO LT175, AGONISTA DUALE DEI RECETTORI NUCLEARI PPARalfa E PPARgamma 62
New rivastigmine-like compounds for the potential treatment of Alzheimer’s disease: a multi-target approach 61
null 56
Novel dual PPARalpha/gamma Agonists, as hypoglycemic and antidiabetic agents 56
NEW CHIRAL DERIVATIVES OF 2-(4-PHENYL-PHENOXY)-3-PHENYLPROPANOIC ACID WITH PPARalpha/gamma DUAL ACTIVITY. 55
Totale 11.176
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Categoria #
all - tutte 56.371
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.371
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021382 0 0 0 0 0 0 0 0 0 196 101 85
2021/2022802 61 59 18 20 34 52 27 41 40 44 130 276
2022/20231.340 214 122 90 97 146 172 15 161 236 18 42 27
2023/2024628 36 82 35 35 59 147 44 38 27 26 29 70
2024/20252.644 180 78 219 123 97 155 278 243 149 174 297 651
2025/20265.060 690 298 436 844 577 282 546 215 581 591 0 0
Totale 14.327