IRIS
PIEMONTESE, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 4.693
EU - Europa 1.293
AS - Asia 835
SA - Sud America 19
OC - Oceania 6
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 6.854
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Nazione #
US - Stati Uniti d'America 4.677
CN - Cina 481
SE - Svezia 332
IT - Italia 309
SG - Singapore 252
GB - Regno Unito 112
FR - Francia 100
DE - Germania 93
RU - Federazione Russa 91
UA - Ucraina 88
FI - Finlandia 76
IN - India 29
VN - Vietnam 24
IE - Irlanda 19
BE - Belgio 16
CA - Canada 16
BR - Brasile 14
CH - Svizzera 11
PT - Portogallo 11
IR - Iran 10
HK - Hong Kong 9
ES - Italia 7
NL - Olanda 6
AT - Austria 5
AU - Australia 5
ID - Indonesia 5
KR - Corea 5
TW - Taiwan 5
PL - Polonia 4
CZ - Repubblica Ceca 3
EU - Europa 3
MY - Malesia 3
TH - Thailandia 3
AR - Argentina 2
BD - Bangladesh 2
CL - Cile 2
EG - Egitto 2
GR - Grecia 2
IL - Israele 2
JP - Giappone 2
LT - Lituania 2
BG - Bulgaria 1
CO - Colombia 1
DK - Danimarca 1
EE - Estonia 1
HR - Croazia 1
IQ - Iraq 1
KZ - Kazakistan 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
ML - Mali 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
TR - Turchia 1
Totale 6.854
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Città #
Fairfield 609
Chandler 476
Woodbridge 437
Ashburn 401
Houston 320
Cambridge 287
Nyköping 269
Seattle 242
Jacksonville 208
Ann Arbor 202
Wilmington 191
Singapore 181
Roxbury 113
Lawrence 112
Nanjing 89
Bari 85
Beijing 83
Des Moines 68
New York 65
Princeton 62
Inglewood 56
Boardman 50
Jiaxing 32
Hebei 28
Marseille 28
Dong Ket 24
San Diego 23
Santa Clara 21
Shanghai 21
Boydton 20
Guangzhou 20
London 20
Brooklyn 19
Dublin 19
Munich 18
Nanchang 18
Brussels 16
Milan 15
Naples 15
Redwood City 15
Changsha 14
Paris 14
Los Angeles 12
Augusta 11
Helsinki 11
Lisbon 11
Shenyang 11
Toronto 11
Washington 11
Falls Church 10
Shenzhen 10
Salerno 9
Tianjin 9
Wuhan 9
Wuxi 9
Bitonto 8
Dearborn 8
Frankfurt am Main 7
Hong Kong 7
Jinhua 7
Kilburn 7
Lausanne 7
Leawood 7
Patna 7
Rome 6
San Francisco 6
Zhengzhou 6
Ardabil 5
Brindisi 5
Catania 5
Madrid 5
Pune 5
Bandung 4
Barry 4
Foggia 4
Hounslow 4
Jinan 4
Kunming 4
San Mateo 4
Taranto 4
Turin 4
West Jordan 4
Alexandria 3
Amsterdam 3
Bedford 3
Bhubaneswar 3
Brahmapur 3
Brno 3
Chiswick 3
Cleveland 3
Detroit 3
Edinburgh 3
Florence 3
Hangzhou 3
Nagold 3
Napoli 3
Ottawa 3
Serdang 3
Simi Valley 3
Taizhou 3
Totale 5.342
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Nome #
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity 160
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity 140
An efficient synthesis of the optically active isomers of 2H-1,4-benzoxazine derivatives, novel KATP channel modulators 135
Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity 129
Deep eutectic solvents as novel and effective extraction media for quantitative determination of Ochratoxin A in wheat and derived products 125
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 121
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of CLC-Kb channels 121
Comparative LC Enantioseparation of Novel PPAR Agonists on Cellulose- and Amylose-Based Chiral Stationary Phases 119
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 115
Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists 113
Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer′s disease therapy 111
New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge 106
Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease 104
Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks? 102
Reduction of aflatoxins in apricot kernels by electronic and manual color sorting 101
Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment 101
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation 101
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression 99
Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update 99
An innovative approach for the treatment of Alzheimer’s disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions 99
An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands 96
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection 95
ChemInform Abstract: Convenient Synthesis of Some 3-Phenyl-1-benzofuran-2-carboxylic Acid Derivatives as New Potential Inhibitors of CLC-Kb Channels. 93
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 89
Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates 86
Miscele eutettiche come solventi biocompatibili a basso impatto ambientale per l’estrazione e la determinazione di metaboliti secondari fungini in matrici alimentari 85
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction. 85
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 83
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 80
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity. 79
Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases 77
The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs 77
Synthesis, Biological Evaluation, and Molecular Modeling Investigation of Chiral Phenoxyacetic Acid Analogues with PPARalpha and PPARgamma Agonist Activity 76
Design, synthesis, and in vitro evaluation of hydroxybenzimidazole-donepezil analogues as multitarget-directed ligands for the treatment of Alzheimer's disease 76
Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors 74
Effect of gaseous ozone treatments on DON, microbial contaminants and technological parameters of wheat and semolina 73
Aspergillus carbonarius proteases and their possible activity in Ochratoxin A degradation 71
Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents 69
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor alpha/gamma ligand LT175 68
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 67
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation 65
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 65
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 63
Natural compounds as FAAH inhibitors: preliminary screening and potential developments 61
Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors alpha/gamma agonists 58
Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions 56
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 56
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1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 55
Climate change effect on ochratoxin A production and gene expression in Aspergillus carbonarius 55
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 55
Deep Eutectic Solvents as effective media for the extraction of small molecules from natural sources 51
Exploiting hydroxyphenylbenzimidazol-based hybrids for metal-modulation in potential anti-Alzheimer´s drugs 50
(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 50
Natural plant food supplements and food coloring agents derived from Vitis Vinifera: a new source of human exposure to ochratoxin A 49
Plant Food Supplements and food coloring agents derived from Vitis vinifera, a new source of human exposure to Ochratoxin A 49
(contributo in convegno) MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY; CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 49
SINTESI E VALUTAZIONE BIOLOGICA DI DERIVATI SEMI-RIGIDI DELL'ACIDO 2-(4-CLOROFENOSSI)-3-FENIL-PROPANOICO COME BLOCCANTI DEI CANALI AL CLORO VOLTAGGIO-DIPENDENTI CLC-K 48
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 48
Processo e impianto per il trattamento di mosti e vini 48
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists 47
Mixing Traditional and Innovative Approaches for the Prevention and Treatment of Neurodegenerative and Cardiovascular Diseases: An Overview 46
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 46
Synthesis and biological activity evaluation of novel diphenylmethane-based ligands for PPARα and PPARγ 41
Ozone treatment as a possible strategy for reductiono of mycotoxins, pesticides and microbial contamination in durum wheat 41
Synthesis of Chelating Agents Potentially Useful as Markers for Neurodegenerative Diseases Using Deep Eutectic Solvents 40
Deep Eutectic Solvents as effective media for the synthesis of Donepezil structure-based hybrids with metal-chelating properties 40
Novel small molecules for PPARs modulation and their potential use for treatment of metabolic disorders 40
Synthesis of New Copper and Zinc Chelators with Potential Therapeutic Application in the Neurodegenerative Diseases 39
Natural scaffolds with potential metal chelating activity for the multi-target therapy of Alzheimer's Disease: a preliminary study 39
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 39
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AGONISTI DEI RECETTORI NUCLEARI PPARs COME POTENZIALI NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DELLA SINDROME METABOLICA. 38
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Food Coloring Agents and Plant Food Supplements Derived from Vitis vinifera: A New Source of Human Exposure to Ochratoxin A 37
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease 37
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Making traditional Italian almond sweets: effects on aflatoxins levels and distribution in final and waste products. 35
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EFFETTI DERIVANTI DALL'INTRODUZIONE DI SOSTITUENTI SUL NUCLEO DIFENILICO DEL COMPOSTO LT175, AGONISTA DUALE DEI RECETTORI NUCLEARI PPARalfa E PPARgamma 35
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 35
Can foods influence the onset and progress of neurodegenerative diseases? 33
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Determinanti Molecolari della Selettività di Recettori Nucleari: Analisi Chemiometrica e Docking di Agonisti Selettivi di Recettori PPARs 31
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Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 26
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 25
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Metal chelators for the multi-target therapy of Alzheimer's Disease: isolation/synthesis and preliminary biological evaluation of new natural and synthetic compounds. 25
Totale 6.359
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Categoria #
all - tutte 34.079
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.079
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020955 0 0 0 0 0 85 196 151 193 134 142 54
2020/20211.191 265 65 56 110 52 29 95 74 63 196 101 85
2021/2022802 61 59 18 20 34 52 27 41 40 44 130 276
2022/20231.340 214 122 90 97 146 172 15 161 236 18 42 27
2023/2024628 36 82 35 35 59 147 44 38 27 26 29 70
2024/2025847 180 78 219 123 97 150 0 0 0 0 0 0
Totale 7.470