IRIS
PIEMONTESE, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 7.473
AS - Asia 3.578
EU - Europa 3.000
SA - Sud America 1.078
Continente sconosciuto - Info sul continente non disponibili 720
AF - Africa 164
OC - Oceania 10
Totale 16.023
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Nazione #
US - Stati Uniti d'America 7.315
SG - Singapore 1.326
IT - Italia 1.167
BR - Brasile 856
CN - Cina 841
HK - Hong Kong 414
SE - Svezia 338
RU - Federazione Russa 326
VN - Vietnam 316
FR - Francia 259
GB - Regno Unito 214
DE - Germania 213
IN - India 169
BD - Bangladesh 134
FI - Finlandia 132
UA - Ucraina 105
CA - Canada 77
ID - Indonesia 77
AR - Argentina 64
IQ - Iraq 44
CO - Colombia 42
EC - Ecuador 42
TR - Turchia 40
AT - Austria 34
ZA - Sudafrica 33
JP - Giappone 30
MX - Messico 29
PL - Polonia 29
CI - Costa d'Avorio 28
ES - Italia 27
IE - Irlanda 23
NL - Olanda 23
VE - Venezuela 22
MA - Marocco 21
PH - Filippine 20
BE - Belgio 19
PT - Portogallo 19
EG - Egitto 16
CH - Svizzera 15
KE - Kenya 14
MY - Malesia 14
SA - Arabia Saudita 14
CL - Cile 13
PE - Perù 13
PY - Paraguay 13
JM - Giamaica 12
AE - Emirati Arabi Uniti 11
LT - Lituania 11
PK - Pakistan 11
IR - Iran 10
KR - Corea 10
UZ - Uzbekistan 10
AU - Australia 9
CR - Costa Rica 9
TN - Tunisia 9
IL - Israele 8
JO - Giordania 8
OM - Oman 8
TT - Trinidad e Tobago 8
AL - Albania 7
AZ - Azerbaigian 7
NP - Nepal 7
TW - Taiwan 7
UY - Uruguay 7
DZ - Algeria 6
KZ - Kazakistan 6
BO - Bolivia 5
CZ - Repubblica Ceca 5
DO - Repubblica Dominicana 5
GA - Gabon 5
LB - Libano 5
SN - Senegal 5
TH - Thailandia 5
BH - Bahrain 4
EE - Estonia 4
ET - Etiopia 4
GR - Grecia 4
HN - Honduras 4
MD - Moldavia 4
PA - Panama 4
SC - Seychelles 4
SV - El Salvador 4
CY - Cipro 3
DK - Danimarca 3
EU - Europa 3
HR - Croazia 3
KW - Kuwait 3
LY - Libia 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
AM - Armenia 2
BF - Burkina Faso 2
BG - Bulgaria 2
BY - Bielorussia 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
LA - Repubblica Popolare Democratica del Laos 2
LV - Lettonia 2
MG - Madagascar 2
Totale 15.276
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Città #
Ashburn 814
Singapore 633
Fairfield 609
San Jose 538
Chandler 476
Woodbridge 438
Hong Kong 405
Houston 332
Milan 332
Cambridge 287
Nyköping 269
Seattle 249
Council Bluffs 234
Beijing 220
Jacksonville 210
Ann Arbor 202
Wilmington 193
Dallas 136
Ho Chi Minh City 126
New York 126
Bari 119
Lauterbourg 115
Roxbury 113
Lawrence 112
Rome 109
Los Angeles 92
Nanjing 91
Santa Clara 87
São Paulo 74
Des Moines 68
Boardman 62
Hanoi 62
Helsinki 62
Princeton 62
Inglewood 56
Munich 50
Jakarta 49
Figino 47
Chicago 46
Brooklyn 44
Naples 44
Frankfurt am Main 41
Buffalo 34
Orem 34
Jiaxing 33
Columbus 32
London 31
Moscow 31
Rio de Janeiro 31
Turin 30
Atlanta 29
Marseille 29
Tokyo 29
Abidjan 28
Hebei 28
North Bergen 27
San Diego 25
San Francisco 25
Baghdad 24
Belo Horizonte 24
Chennai 24
Dong Ket 24
Falkenstein 24
Shanghai 24
Warsaw 24
Boydton 23
Dublin 23
Montreal 23
Fragagnano 21
Guangzhou 21
Poplar 21
Brasília 19
Brussels 19
Johannesburg 19
Lisbon 19
Nanchang 18
Denver 17
Paris 17
Phoenix 17
Bologna 16
Changsha 16
Toronto 16
Basingstoke 15
Dhaka 15
Redwood City 15
Langenzersdorf 14
Manchester 14
Medellín 14
Nuremberg 14
Quito 14
Redondo Beach 14
Washington 14
Amsterdam 13
Boston 13
Haiphong 13
Augusta 12
Cairo 12
Florence 12
Guayaquil 12
Mexico City 12
Totale 9.645
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Nome #
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity 239
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity 211
An efficient synthesis of the optically active isomers of 2H-1,4-benzoxazine derivatives, novel KATP channel modulators 210
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease 199
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of CLC-Kb channels 194
On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles 191
Deep eutectic solvents as novel and effective extraction media for quantitative determination of Ochratoxin A in wheat and derived products 186
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 175
An update about the crucial role of stereochemistry on the effects of Peroxisome Proliferator-Activated Receptor ligands 169
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 169
Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease 168
ChemInform Abstract: Convenient Synthesis of Some 3-Phenyl-1-benzofuran-2-carboxylic Acid Derivatives as New Potential Inhibitors of CLC-Kb Channels. 166
An innovative approach for the treatment of Alzheimer’s disease: the role of peroxisome proliferator-activated receptors and their ligands in development of alternative therapeutic interventions 166
Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists 166
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 163
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 163
Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors 161
Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity 159
Reduction of aflatoxins in apricot kernels by electronic and manual color sorting 158
Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer′s disease therapy 158
Comparative LC Enantioseparation of Novel PPAR Agonists on Cellulose- and Amylose-Based Chiral Stationary Phases 155
Occurrence of patulin in conventional and organic fruit products in Italy and subsequent exposure assessment 154
New approaches for prevention and treatment of Alzheimer's disease: a fascinating challenge 154
Processo e impianto per il trattamento di mosti e vini 153
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation 149
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 149
Plant Food Supplements with Antioxidant Properties for the Treatment of Chronic and Neurodegenerative Diseases: Benefits or Risks? 144
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection 141
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 141
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 141
Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates 140
Miscele eutettiche come solventi biocompatibili a basso impatto ambientale per l’estrazione e la determinazione di metaboliti secondari fungini in matrici alimentari 139
Design, synthesis, and in vitro evaluation of hydroxybenzimidazole-donepezil analogues as multitarget-directed ligands for the treatment of Alzheimer's disease 139
A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties 136
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression 135
AGONISTI DEI RECETTORI NUCLEARI PPARs COME POTENZIALI NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DELLA SINDROME METABOLICA. 135
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 133
Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update 132
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 131
Aspergillus carbonarius proteases and their possible activity in Ochratoxin A degradation 131
Natural plant food supplements and food coloring agents derived from Vitis Vinifera: a new source of human exposure to ochratoxin A 129
(contributo in convegno) MOLECULAR DETERMINANTS FOR NUCLEAR RECEPTORS SELECTIVITY; CHEMOMETRIC ANALYSIS, DOCKINGS AND SITE-DIRECTED MUTAGENESIS OF DUAL PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS α/γ AGONISTS 128
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor alpha/gamma ligand LT175 125
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand–macromolecule interaction. 125
(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 125
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity. 124
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 124
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 122
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 120
Synthesis, Biological Evaluation, and Molecular Modeling Investigation of Chiral Phenoxyacetic Acid Analogues with PPARalpha and PPARgamma Agonist Activity 120
The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs 120
Comparative analysis of enantioselective separation of novel PPAR agonists by HPLC on cellulose- and amylose-based chiral stationary phases 118
Exploiting hydroxyphenylbenzimidazol-based hybrids for metal-modulation in potential anti-Alzheimer´s drugs 116
Effect of gaseous ozone treatments on DON, microbial contaminants and technological parameters of wheat and semolina 116
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation 115
Exploring the chelating capacity of 2-hydroxyphenyl-benzimidazole based hybrids with multi-target ability as anti-Alzheimer's agents 113
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 112
Deep Eutectic Solvents as effective media for the extraction of small molecules from natural sources 108
Climate change effect on ochratoxin A production and gene expression in Aspergillus carbonarius 107
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 106
Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates 105
Novel Phenothiazine/Donepezil-Like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease 104
Natural compounds as FAAH inhibitors: preliminary screening and potential developments 104
Plant Food Supplements and food coloring agents derived from Vitis vinifera, a new source of human exposure to Ochratoxin A 101
Can foods influence the onset and progress of neurodegenerative diseases? 101
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 100
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease 99
Effects of temperature and water activity change on ecophysiology of ochratoxigenic Aspergillus carbonarius in field-simulating conditions 98
Ozone treatment as a possible strategy for reductiono of mycotoxins, pesticides and microbial contamination in durum wheat 96
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 95
Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors alpha/gamma agonists 94
3-((2-(4-Chloro-5-ethoxy-2-nitrophenoxy)acetamido)methyl)phenyl-dimethylcarbamate 93
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy 92
Synthesis of Chelating Agents Potentially Useful as Markers for Neurodegenerative Diseases Using Deep Eutectic Solvents 92
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists 92
Mixing Traditional and Innovative Approaches for the Prevention and Treatment of Neurodegenerative and Cardiovascular Diseases: An Overview 91
Synthesis of New Copper and Zinc Chelators with Potential Therapeutic Application in the Neurodegenerative Diseases 90
Natural scaffolds with potential metal chelating activity for the multi-target therapy of Alzheimer's Disease: a preliminary study 88
Food Coloring Agents and Plant Food Supplements Derived from Vitis vinifera: A New Source of Human Exposure to Ochratoxin A 88
Novel small molecules for PPARs modulation and their potential use for treatment of metabolic disorders 87
Making traditional Italian almond sweets: effects on aflatoxins levels and distribution in final and waste products. 86
Deep Eutectic Solvents as effective media for the synthesis of Donepezil structure-based hybrids with metal-chelating properties 86
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function 86
Synthesis and biological activity evaluation of novel diphenylmethane-based ligands for PPARα and PPARγ 84
Multiple causes, multiple targets: FAAH as a centerpiece for therapy of multifactorial pathologies. 84
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ 83
SINTESI E VALUTAZIONE BIOLOGICA DI DERIVATI SEMI-RIGIDI DELL'ACIDO 2-(4-CLOROFENOSSI)-3-FENIL-PROPANOICO COME BLOCCANTI DEI CANALI AL CLORO VOLTAGGIO-DIPENDENTI CLC-K 83
Multi-Target Approach for the Design of New Compounds Potentially Useful for the Prevention and Treatment of Cardiovascular and/or Neurodegenerative Diseases 82
Role of copper chelating agents: between old applications and new perspectives in neuroscience 80
Repurposing Rivastigmine Anti-AD Drug By Aryloxyacetic Hybridization: Biometal Chelation And Potential Increased Anti-Amyloidogenic Ability 79
Occurrence and characterization of penicillium species isolated from post-harvest apples in lebanon 78
Lentil (Lens culinaria) and its by-products inclusion in livestock nutrition: present insights and emerging trends in rabbit and poultry system 77
Discovery of a dual PPARα/γ partial agonist displaying antisteatotic and antidiabetic properties: in silico studies and X-ray structure determination 74
From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs 74
Determinanti Molecolari della Selettività di Recettori Nucleari: Analisi Chemiometrica e Docking di Agonisti Selettivi di Recettori PPARs 74
EFFETTI DERIVANTI DALL'INTRODUZIONE DI SOSTITUENTI SUL NUCLEO DIFENILICO DEL COMPOSTO LT175, AGONISTA DUALE DEI RECETTORI NUCLEARI PPARalfa E PPARgamma 71
Metal chelators for the multi-target therapy of Alzheimer's Disease: isolation/synthesis and preliminary biological evaluation of new natural and synthetic compounds. 69
Novel dual PPARalpha/gamma Agonists, as hypoglycemic and antidiabetic agents 66
Hydroxyphenyl-benzimidazole based hybrids as metal chelating mimetics of the anti-Alzheimer's drug Donepezil 65
New rivastigmine-like compounds for the potential treatment of Alzheimer’s disease: a multi-target approach 64
Totale 12.231
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Categoria #
all - tutte 64.016
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.016
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022682 0 0 18 20 34 52 27 41 40 44 130 276
2022/20231.340 214 122 90 97 146 172 15 161 236 18 42 27
2023/2024628 36 82 35 35 59 147 44 38 27 26 29 70
2024/20252.644 180 78 219 123 97 155 278 243 149 174 297 651
2025/20265.940 690 298 436 844 577 282 546 215 581 634 238 599
2026/2027816 214 320 282 0 0 0 0 0 0 0 0 0
Totale 16.023