IRIS
STEFANACHI, ANGELA
 Distribuzione geografica
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Continente #
NA - Nord America 6.748
AS - Asia 2.411
EU - Europa 1.908
SA - Sud America 544
AF - Africa 91
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 4
Totale 11.710
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Nazione #
US - Stati Uniti d'America 6.670
SG - Singapore 908
CN - Cina 691
BR - Brasile 447
SE - Svezia 331
DE - Germania 322
IT - Italia 299
RU - Federazione Russa 258
HK - Hong Kong 256
VN - Vietnam 246
FR - Francia 148
GB - Regno Unito 147
FI - Finlandia 130
UA - Ucraina 114
IN - India 63
CA - Canada 40
CI - Costa d'Avorio 40
BD - Bangladesh 37
ID - Indonesia 34
AR - Argentina 33
TR - Turchia 29
BE - Belgio 27
IQ - Iraq 26
NL - Olanda 23
CO - Colombia 19
PK - Pakistan 19
MX - Messico 17
ZA - Sudafrica 17
CZ - Repubblica Ceca 15
IE - Irlanda 15
AT - Austria 14
JP - Giappone 14
ES - Italia 13
PL - Polonia 12
IR - Iran 11
PH - Filippine 11
PY - Paraguay 10
SA - Arabia Saudita 10
UZ - Uzbekistan 9
BO - Bolivia 8
EC - Ecuador 8
MA - Marocco 8
MY - Malesia 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
AL - Albania 6
LT - Lituania 6
AZ - Azerbaigian 5
CH - Svizzera 5
CL - Cile 4
EG - Egitto 4
EU - Europa 4
JM - Giamaica 4
KE - Kenya 4
KG - Kirghizistan 4
NP - Nepal 4
PE - Perù 4
PS - Palestinian Territory 4
RO - Romania 4
VE - Venezuela 4
CR - Costa Rica 3
DK - Danimarca 3
ET - Etiopia 3
GT - Guatemala 3
KZ - Kazakistan 3
NG - Nigeria 3
OM - Oman 3
SR - Suriname 3
UY - Uruguay 3
AO - Angola 2
AU - Australia 2
EE - Estonia 2
GR - Grecia 2
HU - Ungheria 2
IL - Israele 2
JO - Giordania 2
LB - Libano 2
NZ - Nuova Zelanda 2
PA - Panama 2
RS - Serbia 2
SY - Repubblica araba siriana 2
AD - Andorra 1
BB - Barbados 1
BH - Bahrain 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GD - Grenada 1
GE - Georgia 1
GI - Gibilterra 1
GP - Guadalupe 1
GY - Guiana 1
HN - Honduras 1
HT - Haiti 1
LV - Lettonia 1
ME - Montenegro 1
MK - Macedonia 1
MT - Malta 1
NI - Nicaragua 1
PR - Porto Rico 1
PT - Portogallo 1
Totale 11.705
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Città #
Dallas 1.709
Ashburn 507
Singapore 500
Fairfield 476
Chandler 446
Woodbridge 315
San Jose 313
Hong Kong 253
Beijing 248
Jacksonville 245
Nyköping 234
Seattle 228
Houston 220
Wilmington 197
Ann Arbor 183
Cambridge 182
Bari 126
Dong Ket 86
Munich 83
Nanjing 80
New York 78
Lauterbourg 76
Roxbury 73
Lawrence 71
Los Angeles 67
Helsinki 58
Boardman 57
Ho Chi Minh City 47
Brooklyn 43
Princeton 42
Abidjan 40
Des Moines 39
Falkenstein 39
Hanoi 39
São Paulo 35
Buffalo 34
Council Bluffs 31
Dearborn 30
Brussels 27
North Bergen 27
Inglewood 25
Santa Clara 25
Frankfurt am Main 24
London 23
Nanchang 23
Jakarta 22
Orem 22
Atlanta 21
Guangzhou 21
Kansas City 21
Marseille 21
Shenyang 21
Jiaxing 19
Hebei 18
Milan 18
Moscow 18
Amsterdam 16
Chicago 16
Nuremberg 16
Dublin 15
San Diego 15
Johannesburg 14
Rio de Janeiro 13
Toronto 13
Washington 13
Boydton 12
Paris 12
Tokyo 12
Turku 12
Campinas 11
Shanghai 11
Zhengzhou 11
Boston 10
Montreal 10
Poplar 10
Stockholm 10
Tianjin 10
Ardabil 9
Baghdad 9
Belo Horizonte 9
Changsha 9
Chennai 9
Denver 9
Dhaka 9
Florence 9
Triggiano 9
Warsaw 9
Brasília 8
Medellín 8
Ningbo 8
Pune 8
Rome 8
Tashkent 8
The Dalles 8
West Jordan 8
Ankara 7
Brno 7
Haiphong 7
Jinan 7
Phoenix 7
Totale 8.377
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Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.073
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.058
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R) 202
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 200
Mind the Gap ! A Journey towards Computational Toxicology 190
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 187
Bcr-abl tyrosine kinase inhibitors in the treatment of pediatric cml 182
Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma 178
Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl Nicotinamides 174
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor 168
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 167
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 163
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 161
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration 160
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 157
Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness 156
A novel strategy for the treatment of Hodgkin lymphoma 155
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 150
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 148
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 146
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 143
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 139
A multitarget approach in cancer research 138
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 137
A Multi-Objective Optimization Algorithm for Molecular Design 136
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 134
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation 133
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies 132
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 131
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 131
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS 127
Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine 126
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 126
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 125
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 125
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 121
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 119
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies 118
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 116
Design, synthesis and biological evaluation of 2-aminobenzanilide derivatives as potent and selective HDAC inhibitors 115
Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to 115
Hydroxy-propil-β-cyclodextrin inclusion complexes of two biphenylnicotinamide derivatives: Formulation and anti-proliferative activity evaluation in pancreatic cancer cell models 114
Strategies of multi-objective optimization in drug discovery and development 112
Enhancing the Sensitivity of Biotinylated Surfaces by Tailoring the Design of the Mixed Self-Assembled Monolayer Synthesis 111
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 109
Solid Phase and Microwave Assisted Synthesis of Focused Libraries of Imatinib Analogues 109
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry 108
Computational methods for the design of potent aromatase inhibitors 108
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. 106
Synthesis of 1-Substituted-6-methyluracils 105
Design, Synthesis and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium-like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors 104
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) 103
Solid Phase Synthesis of Safinamide and Analogues as Potent and Selective MAO-B Inhibitors 103
The Role of Cannabinoid Receptors Subtype 2 inCancer A Promising Therapeutical Target 102
Surface composition of mixed self-assembled monolayers on Au by infrared attenuated total reflection spectroscopy 102
DeLA-DrugSelf: Empowering multi-objective de novo design through SELFIES molecular representation 101
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 97
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase 96
Discovery of a potent and selective hetero-bivalent AChE inhibitor via bioisosteric replacement 95
New Strategies in the Chemotherapy of Leukemia: Eradicating Cancer Stem Cells in Chronic Myeloid Leukemia 94
Negatively charged ions to probe self-assembled monolayer reorganization driven by interchain interactions 94
Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques 93
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules 92
Design of multiple-target anticancer agents: a daunting challenge for the medicinal chemist 92
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines from combined ligand- and structure-based approaches 90
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors 90
Heterodimeric dual binding site cholinesterase inhibitors: surfing on the sub-nanomolar affinity 86
N‑Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R) 81
Solid-phase and Microwave Assisted Synthesis of Focused libraries of Imatinib analogues 79
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs 77
Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers 77
Ring closing metathesis mediated synthesis of d-, g- and e-N-HydroxylactaMS as potential coordinating molecular fragments of biologically relevant bivalent metals XX 77
Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Selective Aromatase Inhibitors 74
3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition 73
Fast and highly efficient one-pot synthesis of 9-deazaxanthines 73
Solid phase synthesis of potential PKs inhibitors 70
Cannabinoid receptor subtype 2 (CB2R): Features and targets for medical applications 67
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists 66
Heterodimeric dual binding site cholinesterase inhibitors: surfing on the sub-nanomolar affinity 66
DESIGN SYNTHESIS AND BIOLOGYCAL ACTIVITY OF NEW POTENT GALLOYL-BASED MRP1 INHIBITORS FOR REVERSING MDR 65
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines from combined ligand- and structure-based approaches 65
Playing Around the Coumarin Core in the Discovery of Multimodal Compounds Directed at Alzheimer’s-Related Targets: A Recent Literature Overview 63
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines (9dAX) from combined ligand- and structure-based approaches 63
null 63
In silico design and microwave-assisted solid phase synthesis of focused libraries of enzyme inhibitors with potential in cancer and neurological therapies 60
Synthesis, and Biological Evaluation of 2-Aminobenzanilide Derivatives as Potent and Selective HDAC Inhibitors. 58
CC48 a new CB2R agonist/FAAH inhibitor dual drug blocks gastric cancer progression and overcomes paclitaxel resistance 53
Conformational Restriction of Designer Drugs Reveals Subtype-Selective and Biased CB2Agonists with Neuroprotective Effects 51
Editorial: Coumarins: New synthetic approaches and new pharmacological applications 50
One-pot assembling pyrroloquinoline quinone glucose dehydrogenase with polydopamine to overcome the reproducibility issues of layer-by-layer electrode development 18
Totale 11.967
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Categoria #
all - tutte 39.482
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.482
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021312 0 0 0 0 0 0 0 0 0 119 57 136
2021/2022651 63 80 5 16 24 37 33 26 41 66 95 165
2022/20231.143 169 113 80 96 155 140 13 146 173 11 21 26
2023/2024483 31 56 23 69 35 87 26 9 20 27 18 82
2024/20251.781 55 51 124 82 60 125 226 148 90 76 250 494
2025/20264.795 511 482 1.579 389 405 210 416 114 387 302 0 0
Totale 11.967