IRIS
STEFANACHI, ANGELA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 6.142
AS - Asia 1.993
EU - Europa 1.675
SA - Sud America 431
AF - Africa 69
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 10.317
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.080
SG - Singapore 763
CN - Cina 642
BR - Brasile 390
SE - Svezia 327
DE - Germania 298
RU - Federazione Russa 253
IT - Italia 252
HK - Hong Kong 246
VN - Vietnam 185
GB - Regno Unito 132
UA - Ucraina 108
FI - Finlandia 105
FR - Francia 71
CI - Costa d'Avorio 40
IN - India 38
CA - Canada 33
BE - Belgio 26
ID - Indonesia 25
NL - Olanda 18
TR - Turchia 17
BD - Bangladesh 15
MX - Messico 14
AT - Austria 13
CZ - Repubblica Ceca 13
IE - Irlanda 13
IQ - Iraq 13
AR - Argentina 12
IR - Iran 11
ZA - Sudafrica 11
ES - Italia 10
PL - Polonia 10
CO - Colombia 8
EC - Ecuador 7
PK - Pakistan 7
JP - Giappone 6
AE - Emirati Arabi Uniti 5
AL - Albania 4
CH - Svizzera 4
EU - Europa 4
KG - Kirghizistan 4
MA - Marocco 4
PY - Paraguay 4
GT - Guatemala 3
JM - Giamaica 3
LT - Lituania 3
NG - Nigeria 3
RO - Romania 3
UZ - Uzbekistan 3
AO - Angola 2
AU - Australia 2
BO - Bolivia 2
CL - Cile 2
EE - Estonia 2
GR - Grecia 2
KE - Kenya 2
NP - Nepal 2
OM - Oman 2
PE - Perù 2
SA - Arabia Saudita 2
TN - Tunisia 2
AD - Andorra 1
AZ - Azerbaigian 1
BB - Barbados 1
BH - Bahrain 1
CR - Costa Rica 1
DK - Danimarca 1
DZ - Algeria 1
EG - Egitto 1
ET - Etiopia 1
GD - Grenada 1
GE - Georgia 1
GI - Gibilterra 1
GP - Guadalupe 1
GY - Guiana 1
HN - Honduras 1
HT - Haiti 1
IL - Israele 1
LB - Libano 1
ME - Montenegro 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PH - Filippine 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
RE - Reunion 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SR - Suriname 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
VE - Venezuela 1
Totale 10.317
Salva come PNG Salva come JPEG
Città #
Dallas 1.707
Fairfield 476
Ashburn 451
Chandler 446
Singapore 376
Woodbridge 315
Beijing 245
Jacksonville 245
Hong Kong 243
Nyköping 234
Seattle 228
Houston 219
Wilmington 197
Ann Arbor 183
Cambridge 182
Bari 126
Dong Ket 86
Munich 83
Nanjing 80
Roxbury 73
Lawrence 71
New York 70
Boardman 57
Los Angeles 57
Princeton 42
Brooklyn 41
Abidjan 40
Des Moines 38
Ho Chi Minh City 36
Helsinki 33
Buffalo 32
Dearborn 30
North Bergen 27
Brussels 26
São Paulo 26
Inglewood 25
Hanoi 24
Falkenstein 23
Nanchang 23
London 22
Guangzhou 21
Kansas City 21
Jakarta 20
Marseille 20
Santa Clara 20
Shenyang 20
Hebei 18
Jiaxing 18
Milan 18
Moscow 18
Frankfurt am Main 17
Nuremberg 15
San Diego 15
Council Bluffs 14
Atlanta 13
Dublin 13
Rio de Janeiro 13
Washington 13
Amsterdam 12
Boydton 12
Chicago 12
Paris 12
Turku 12
Toronto 11
Zhengzhou 11
Campinas 10
Orem 10
Shanghai 10
Tianjin 10
Ardabil 9
Boston 9
Changsha 9
Florence 9
Johannesburg 9
Triggiano 9
Belo Horizonte 8
Brasília 8
Chennai 8
Ningbo 8
Poplar 8
Pune 8
Warsaw 8
West Jordan 8
Brno 7
Jinan 7
Montreal 7
Redwood City 7
Stockholm 7
Ankara 6
Denver 6
Lauterbourg 6
Mexico City 6
Norwalk 6
Phoenix 6
Porto Alegre 6
Strasbourg 6
The Dalles 6
Tokyo 6
Campo Grande 5
Contagem 5
Totale 7.590
Salva come PNG Salva come JPEG
Nome #
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1.053
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1.034
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R) 185
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 183
Mind the Gap ! A Journey towards Computational Toxicology 173
Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Aβ40 aggregation in vitro 170
Synthesis and biological evaluation of N-biphenyl-nicotinic based moiety compounds: A new class of antimitotic agents for the treatment of Hodgkin Lymphoma 159
Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl Nicotinamides 159
Bcr-abl tyrosine kinase inhibitors in the treatment of pediatric cml 158
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor 155
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 153
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 146
Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds 143
Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness 141
A novel strategy for the treatment of Hodgkin lymphoma 140
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration 138
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 137
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors 135
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor 131
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 129
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 126
Insights into the complex formed by Matrix Metalloproteinase-2 and alloxan inhibitors: molecular dynamics simulations and free energy calculations 123
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 121
Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases 121
A multitarget approach in cancer research 119
A Multi-Objective Optimization Algorithm for Molecular Design 118
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 118
Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine 117
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 115
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies 115
Human ether-à-go-go-related potassium channel: exploring SAR to improve drug design 111
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 110
Fine Molecular Tuning at Position 4 of 2H-Chromen-2-one Derivatives in the Search of Potent and Selective Monoamine Oxidase B Inhibitors 110
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation 108
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles and isoxazoles with biological potential 107
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS 107
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 107
Design, synthesis and biological evaluation of 2-aminobenzanilide derivatives as potent and selective HDAC inhibitors 106
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 106
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies 105
Computational methods for the design of potent aromatase inhibitors 103
Synthesis of 1-Substituted-6-methyluracils 101
Solid Phase and Microwave Assisted Synthesis of Focused Libraries of Imatinib Analogues 100
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. 96
Design, Synthesis and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium-like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors 95
Solid Phase Synthesis of Safinamide and Analogues as Potent and Selective MAO-B Inhibitors 94
Hydroxy-propil-β-cyclodextrin inclusion complexes of two biphenylnicotinamide derivatives: Formulation and anti-proliferative activity evaluation in pancreatic cancer cell models 92
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry 91
Enhancing the Sensitivity of Biotinylated Surfaces by Tailoring the Design of the Mixed Self-Assembled Monolayer Synthesis 89
Strategies of multi-objective optimization in drug discovery and development 87
Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to 87
New Strategies in the Chemotherapy of Leukemia: Eradicating Cancer Stem Cells in Chronic Myeloid Leukemia 85
Surface composition of mixed self-assembled monolayers on Au by infrared attenuated total reflection spectroscopy 85
Discovery of a potent and selective hetero-bivalent AChE inhibitor via bioisosteric replacement 84
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase 83
Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors 82
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 80
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines from combined ligand- and structure-based approaches 80
Negatively charged ions to probe self-assembled monolayer reorganization driven by interchain interactions 80
Heterodimeric dual binding site cholinesterase inhibitors: surfing on the sub-nanomolar affinity 79
The Role of Cannabinoid Receptors Subtype 2 inCancer A Promising Therapeutical Target 78
DeLA-DrugSelf: Empowering multi-objective de novo design through SELFIES molecular representation 77
Design of multiple-target anticancer agents: a daunting challenge for the medicinal chemist 77
Inhibiting Aβ1-40 in vitro aggregation by glycine-based molecular tongs: rational design and mechanistic implications 76
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules 75
Solid-phase and Microwave Assisted Synthesis of Focused libraries of Imatinib analogues 70
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) 68
Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques 68
Ring closing metathesis mediated synthesis of d-, g- and e-N-HydroxylactaMS as potential coordinating molecular fragments of biologically relevant bivalent metals XX 67
Fast and highly efficient one-pot synthesis of 9-deazaxanthines 66
Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Selective Aromatase Inhibitors 64
null 63
N‑Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R) 59
Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers 59
Solid phase synthesis of potential PKs inhibitors 59
3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition 55
DESIGN SYNTHESIS AND BIOLOGYCAL ACTIVITY OF NEW POTENT GALLOYL-BASED MRP1 INHIBITORS FOR REVERSING MDR 55
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines (9dAX) from combined ligand- and structure-based approaches 55
Heterodimeric dual binding site cholinesterase inhibitors: surfing on the sub-nanomolar affinity 55
Structural insights into hA2B affinity and selectivity of 9-deazaxanthines from combined ligand- and structure-based approaches 55
Synthesis, and Biological Evaluation of 2-Aminobenzanilide Derivatives as Potent and Selective HDAC Inhibitors. 54
In silico design and microwave-assisted solid phase synthesis of focused libraries of enzyme inhibitors with potential in cancer and neurological therapies 54
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs 52
Cannabinoid receptor subtype 2 (CB2R): Features and targets for medical applications 51
Playing Around the Coumarin Core in the Discovery of Multimodal Compounds Directed at Alzheimer’s-Related Targets: A Recent Literature Overview 48
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists 44
Editorial: Coumarins: New synthetic approaches and new pharmacological applications 37
Conformational Restriction of Designer Drugs Reveals Subtype-Selective and Biased CB2Agonists with Neuroprotective Effects 30
CC48 a new CB2R agonist/FAAH inhibitor dual drug blocks gastric cancer progression and overcomes paclitaxel resistance 28
One-pot assembling pyrroloquinoline quinone glucose dehydrogenase with polydopamine to overcome the reproducibility issues of layer-by-layer electrode development 10
Totale 10.574
Salva come PNG Salva come JPEG
Categoria #
all - tutte 36.915
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.915
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021483 0 0 0 0 0 34 31 51 55 119 57 136
2021/2022651 63 80 5 16 24 37 33 26 41 66 95 165
2022/20231.143 169 113 80 96 155 140 13 146 173 11 21 26
2023/2024483 31 56 23 69 35 87 26 9 20 27 18 82
2024/20251.781 55 51 124 82 60 125 226 148 90 76 250 494
2025/20263.402 511 482 1.579 389 405 36 0 0 0 0 0 0
Totale 10.574