STEFANACHI, ANGELA
STEFANACHI, ANGELA
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships
2008-01-01 Stefanachi, Angela; Nicolotti, Orazio; Leonetti, Francesco; Cellamare, Saverio; Campagna, Francesco; Loza, Mi; Brea, Jm; Mazza, F; Gavuzzo, E; Carotti, Angelo
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships
2009-01-01 Fernandez, F; Caamano, O; Nieto, Mi; Lopez, C; Garcia Mera, X; Stefanachi, Angela; Nicolotti, Orazio; Loza, Mi; Brea, J; Esteve, C; Segarra, V; Vidal, B; Carotti, Angelo
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor
2008-01-01 Stefanachi, A; BREA J., M; CADAVID M., I; CENTENO N., B; Esteve, C; LOZA M., I; Martinez, A; Nieto, R; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Vidal, B.; Carotti, A
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS
2013-01-01 Pisani, Leonardo; Catto, Marco; Stefanachi, Angela; Leonetti, F; Campagna, Francesco; Nicolotti, O; SOTO OTERO, R; Carotti, A.
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders
2013-01-01 Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A.
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B
2004-01-01 Carotti, Angelo; Stefanachi, Angela; Ravina, E; Sotelo, E; Loza, Mi; Cadavid, Mi; Centeno, Nb; Nicolotti, Orazio
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies
2004-01-01 Carotti, A; CADAVID M., I; CENTENO N., B; Esteve, C; Fontaine, F; GUTIÉRREZ DE TERÁN, H; LOZA M., I; Martinez, A; Nicolotti, Orazio; Nieto, R; Pastor, M; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Stefanachi, Angela
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies
2003-01-01 Stefanachi, Angela
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor.
2010-01-01 Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A.
A Multi-Objective Optimization Algorithm for Molecular Design
2009-01-01 Giangreco, I; Nicolotti, Orazio; Miscioscia T., F; Convertino, M; Mangiatordi G., F; Siragusa, L; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Carotti, A.
A multitarget approach in cancer research
2009-01-01 Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A.
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry
2009-01-01 Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A.
A novel strategy for the treatment of Hodgkin lymphoma
2014-01-01 Stolfa, D.; Porcelli, L.; Quatrale, A. E.; Stefanachi, Angela; Iacobazzi, R. M.; Sidella, L.; Cellamare, Saverio; Azzariti, A.
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation
2009-01-01 Stolfa, A; Cellamare, Saverio; Stefanachi, Angela; Catto, Marco; Leonetti, Francesco; Nicolotti, Orazio; Carotti, A.
Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to
2020-01-01 Carofiglio, F.; Trisciuzzi, D.; Gambacorta, N.; Leonetti, F.; Stefanachi, A.; Nicolotti, O.
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile
2011-01-01 Leonetti, Francesco; Stefanachi, Angela; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Cellamare, Saverio; Carotti, Angelo
Bcr-abl tyrosine kinase inhibitors in the treatment of pediatric cml
2020-01-01 Carofiglio, F.; Lopalco, A.; Lopedota, A.; Cutrignelli, A.; Nicolotti, O.; Denora, N.; Stefanachi, A.; Leonetti, F.
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration
2020-01-01 Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra
Computational methods for the design of potent aromatase inhibitors
2013-01-01 Favia, Angelo Danilo; Nicolotti, Orazio; Stefanachi, Angela; Leonetti, Francesco; Carotti, Angelo
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase
2011-01-01 Stefanachi, Angela; Favia, Ad; Nicolotti, Orazio; Leonetti, Francesco; Pisani, Leonardo; Catto, Marco; Zimmer, C; Hartmann, Rw; Cellamare, Saverio; Carotti, Angelo
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships | 1-gen-2008 | Stefanachi, Angela; Nicolotti, Orazio; Leonetti, Francesco; Cellamare, Saverio; Campagna, Francesco; Loza, Mi; Brea, Jm; Mazza, F; Gavuzzo, E; Carotti, Angelo | |
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships | 1-gen-2009 | Fernandez, F; Caamano, O; Nieto, Mi; Lopez, C; Garcia Mera, X; Stefanachi, Angela; Nicolotti, Orazio; Loza, Mi; Brea, J; Esteve, C; Segarra, V; Vidal, B; Carotti, Angelo | |
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor | 1-gen-2008 | Stefanachi, A; BREA J., M; CADAVID M., I; CENTENO N., B; Esteve, C; LOZA M., I; Martinez, A; Nieto, R; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Vidal, B.; Carotti, A | |
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS | 1-gen-2013 | Pisani, Leonardo; Catto, Marco; Stefanachi, Angela; Leonetti, F; Campagna, Francesco; Nicolotti, O; SOTO OTERO, R; Carotti, A. | |
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders | 1-gen-2013 | Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A. | |
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B | 1-gen-2004 | Carotti, Angelo; Stefanachi, Angela; Ravina, E; Sotelo, E; Loza, Mi; Cadavid, Mi; Centeno, Nb; Nicolotti, Orazio | |
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies | 1-gen-2004 | Carotti, A; CADAVID M., I; CENTENO N., B; Esteve, C; Fontaine, F; GUTIÉRREZ DE TERÁN, H; LOZA M., I; Martinez, A; Nicolotti, Orazio; Nieto, R; Pastor, M; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Stefanachi, Angela | |
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies | 1-gen-2003 | Stefanachi, Angela | |
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. | 1-gen-2010 | Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A. | |
A Multi-Objective Optimization Algorithm for Molecular Design | 1-gen-2009 | Giangreco, I; Nicolotti, Orazio; Miscioscia T., F; Convertino, M; Mangiatordi G., F; Siragusa, L; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Carotti, A. | |
A multitarget approach in cancer research | 1-gen-2009 | Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A. | |
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry | 1-gen-2009 | Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A. | |
A novel strategy for the treatment of Hodgkin lymphoma | 1-gen-2014 | Stolfa, D.; Porcelli, L.; Quatrale, A. E.; Stefanachi, Angela; Iacobazzi, R. M.; Sidella, L.; Cellamare, Saverio; Azzariti, A. | |
An improved method for the biological evaluation of polyphenol derivatives as potential inhibitors of aβ(1–40) aggregation | 1-gen-2009 | Stolfa, A; Cellamare, Saverio; Stefanachi, Angela; Catto, Marco; Leonetti, Francesco; Nicolotti, Orazio; Carotti, A. | |
Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to | 1-gen-2020 | Carofiglio, F.; Trisciuzzi, D.; Gambacorta, N.; Leonetti, F.; Stefanachi, A.; Nicolotti, O. | |
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile | 1-gen-2011 | Leonetti, Francesco; Stefanachi, Angela; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Cellamare, Saverio; Carotti, Angelo | |
Bcr-abl tyrosine kinase inhibitors in the treatment of pediatric cml | 1-gen-2020 | Carofiglio, F.; Lopalco, A.; Lopedota, A.; Cutrignelli, A.; Nicolotti, O.; Denora, N.; Stefanachi, A.; Leonetti, F. | |
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration | 1-gen-2020 | Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra | |
Computational methods for the design of potent aromatase inhibitors | 1-gen-2013 | Favia, Angelo Danilo; Nicolotti, Orazio; Stefanachi, Angela; Leonetti, Francesco; Carotti, Angelo | |
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase | 1-gen-2011 | Stefanachi, Angela; Favia, Ad; Nicolotti, Orazio; Leonetti, Francesco; Pisani, Leonardo; Catto, Marco; Zimmer, C; Hartmann, Rw; Cellamare, Saverio; Carotti, Angelo |