RUGGIERI, Maddalena
 Distribuzione geografica
Continente #
NA - Nord America 4.429
EU - Europa 1.077
AS - Asia 562
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 6.072
Nazione #
US - Stati Uniti d'America 4.416
CN - Cina 357
SE - Svezia 276
IT - Italia 221
UA - Ucraina 192
SG - Singapore 169
DE - Germania 131
FI - Finlandia 107
GB - Regno Unito 54
FR - Francia 40
BE - Belgio 16
IE - Irlanda 15
IN - India 14
CA - Canada 12
VN - Vietnam 10
ES - Italia 7
IR - Iran 5
CZ - Repubblica Ceca 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 2
LT - Lituania 2
NL - Olanda 2
PL - Polonia 2
RO - Romania 2
AU - Australia 1
BG - Bulgaria 1
CL - Cile 1
EU - Europa 1
GR - Grecia 1
JP - Giappone 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
NZ - Nuova Zelanda 1
PA - Panama 1
RS - Serbia 1
RU - Federazione Russa 1
TH - Thailandia 1
Totale 6.072
Città #
Chandler 522
Fairfield 500
Woodbridge 473
Jacksonville 452
Ashburn 269
Houston 258
Nyköping 220
Ann Arbor 214
Wilmington 196
Seattle 176
Cambridge 171
Singapore 111
Lawrence 106
Roxbury 103
Nanjing 102
Des Moines 69
Bari 65
Beijing 65
Boardman 62
New York 50
Inglewood 42
Princeton 40
Marseille 31
San Diego 27
Brooklyn 26
Nanchang 25
Jiaxing 23
Shenyang 23
Los Angeles 20
Tianjin 20
Hebei 18
Brussels 16
Santa Clara 16
Dublin 15
Helsinki 14
Dearborn 13
Mottola 12
Norwalk 11
Dong Ket 10
Pune 10
Guangzhou 9
Imbersago 9
Munich 9
Augusta 8
Changsha 8
Rome 8
Auburn Hills 7
Monmouth Junction 7
Bisceglie 6
Edmonton 6
Milan 6
Paris 6
San Mateo 6
Wuhan 6
Padova 5
Shanghai 5
Toronto 5
Washington 5
Ardabil 4
Brno 4
Edinburgh 4
Hefei 4
Leawood 4
London 4
Palermo 4
Falls Church 3
Indiana 3
Kilburn 3
Mumbai 3
Ningbo 3
Redwood City 3
Turin 3
Zhengzhou 3
Amantea 2
Brescia 2
Carpi 2
Chieti 2
Fuzhou 2
Hanover 2
Jinan 2
Jinhua 2
Naples 2
Oria 2
Palosco 2
Redmond 2
Taizhou 2
Verona 2
Zurich 2
Acquaviva Delle Fonti 1
Athens 1
Atlanta 1
Auckland 1
Bitetto 1
Blackpool 1
Bor 1
Boston 1
Brindisi 1
Brugherio 1
Bucharest 1
Canberra 1
Totale 4.811
Nome #
Diagnostic and prognostic power of CSF Tau in amyotrophic lateral sclerosis 123
Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment 118
IMMUNOPATOLOGIA DELLA SCLEROSI MULTIPLA 116
Glatiramer Acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from Multiple Sclerosis patients 115
Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4 isoform-dependent sensitivity and specificity. 115
Adhesion molecules and matrix metalloproteinases in Multiple Sclerosis: effects induced by Interferon-beta 109
Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis 107
IFNβ enhances mesenchymal stromal (Stem) cells immunomodulatory function through STAT1-3 activation and mTOR-associated promotion of glucose metabolism 107
Age-related changes of serum N-acetyl-aspartate in healthy controls. 106
Cerebrospinal fluid neurofilament tracks fMRI correlates of attention at the first attack of multiple sclerosis. 98
Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles-New Insights for Structural and Functional Studies 95
Development of an aquaporin-4 orthogonal array of particle-based ELISA for neuromyelitis optica autoantibodies detection 94
Cerebrospinal fluid neurofilament light levels mark grey matter volume in clinically isolated syndrome suggestive of multiple sclerosis 94
The improvement of cognitive functions is associated with a decrease of plasma Osteopontin levels in Natalizumab treated relapsing multiple sclerosis. 89
Serum levels of N-acetylaspartate in Huntington's disease: Preliminary results. 87
BLOOD MMP-9 AND SICAM-1 AS MARKERS OF RIFN-B TREATMENT EFFICACY IN RELAPSING-REMITTING MS 83
CHANGES OF NAIVE AND EFFECTOR/MEMORY T-CELL SUBSETS AND SERUM SOLUBLE ICAM-1 INDUCED BY RIFNB-1B IN MS 83
Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes 83
Serum levels of N-acetyl-aspartate in migraine and tension-type headache. 81
Combination treatment of Glatiramer Acetate and Minocycline affects phenotype expression of blood monocyte-derived dendritic cells in Multiple Sclerosis patients 80
Cerebrospinal fluid neurofilament tracks fMRI correlates of attention at the first attack of Multiple Sclerosis 80
Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis. 80
Serum levels of N-acetyl-aspartate in migraine and tension-type headache. 80
Cerebrospinal fluid analysis and the determination of oligoclonal bands 78
Italian studies on early-onset multiple sclerosis: the present and the future 75
Neurofilament ELISA validation 75
Serum and CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis optica 74
ANTINFLAMMATORY EFFECTS OF RIFNB-1B IN MULTIPLE SCLEROSIS: LONGITUDINAL CHANGES OF THE SERUM SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 (SICAM-1), TNFA AND T-CELL SUBSETS 73
Diagnostics of the neuromyelitis optica spectrum disorders (NMOSD) 73
null 72
Analisi longitudinale dei livelli sierici di ICAM-1 solubile e dei subsets di linfociti T in pazienti con Sclerosi Multipla a decorso remittente in trattamento con IFNb-1b 71
null 71
Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding 70
PBMC of Multiple Sclerosis Patients Show Deregulation of OPA1 Processing Associated with Increased ROS and PHB2 Protein Levels 65
Beta Amyloid 1-40 peptide selectively downregulates MMP-9 production in differentiated SH-SY5Y neuronal cell line 64
Glatiramer acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients 63
Cerebrospinal Fluid and Serum Neurofilament Light Chain Levels in ALS Patients 63
MMP-9 and 2 activities and TIMPs in MS: differences between early and chronic disease 62
CHANGES OF SERUM ICAM-1 AND MMP-9 INDUCED BY RIFNB-1B TREATMENT IN RELAPSING-REMITTING MS 62
null 62
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke 62
Correlations between neutralizing antibodies production and clinical outcomes: analysis in a population-based surveillance italian study of interferon beta treatment in multiple sclerosis patients 61
Serum Soluble ICAM-1 and Gelatinase B Novel Markers of Clinical Efficacy of the RIFN-beta-1b in Relapsing-Remitting Multiple Sclerosis 59
Serum MMPs and TIMPs in Multiple Sclerosis: differences between early and chronic disease 57
Combination treatment of Glatiramer Acetate and Minocycline affects phenotype expression of blood monocyte-derived dendritic cells in Multiple Sclerosis 57
Glatiramer acetate in multiple sclerosis: a review 57
A population-based surveillance Italian study of Interferon beta treatment in Multiple Sclerosis patients: relationships between neutralizing antibodies production and clinical outcomes 56
Decreased levels of serum Gelatinase B in MS patients treated with rIFN-beta-1b 56
CHANGES OF SERUM SOLUBLE ICAM-1 AND MATRIX METALLOPROTEINASE-9 DURING INTERFERON BETA-1B TREATMENT IN RR MS 54
Interferone beta (IFNb) e barriera emato-encefalica nella Sclerosi Multipla: effetto su molecole di adesione e metalloproteasi 54
CHANGES OF SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 (SICAM-1) LEVELS INDUCED BY CORTICOSTEROIDS AND RIFN-BETA-1B IN MULTIPLE SCLEROSIS AND GUILLAIN-BARRÉ SYNDROME 53
Novel anti-inflammatory properties of rIFN-beta-1b in RR MS: recovery of T-suppression and increase of serum sICAM-1 53
Analisi fenotipica di linfociti T di pazienti con Sclerosi Multipla (SM) nel sangue periferico ed in coltura con e senza aggiunta di mitogeni 52
UN ANNO DI TRATTAMENTO CON INTERFERONE B-1B INCREMENTA I LIVELLI SIERICI DI SICAM-1 E RIPRISTINA LA FUNZIONE SOPPRESSORIA DEI T-LINFOCITI IN PAZIENTI CON SM RELAPSING-REMITTING 51
RIFNB DOWNREGULATES TNFA-INDUCED ICAM-1 EXPRESSION ON BRAIN MICROVASCULAR ENDOTHELIAL CELLS (BEMC) AND INCREASES SERUM SOLUBLE ICAM-1 (SICAM-1) IN RR MS 50
LFA-1 EXPRESSION ON CD4+CD45RO+ PBTLS DURING RIFN-BETA-1A TREATMENT IN RR MS: IN VIVO AND IN VITRO STUDY 49
Standard (SD) and triple dose (TD) gadolinium (Gd) enhancing lesions are associated with a similar degree of MMP-9 and TIMP-1 involvement at the blood-brain barrier (BBB) level in Multiple Sclerosis (MS) 49
Antinflammatory effects of rIFNb-1b in multiple sclerosis: longitudinal changes of the serum soluble Intercellular Adhesion Molecule-1 (sICAM-1), TNFa and T-cell subsets 49
A LONGITUDINAL ANALYSIS OF SERUM SOLUBLE ICAM-1 (SICAM-1), TNFA AND T-CELL SUBSETS IN MULTIPLE SCLEROSIS (MS) PATIENTS DURING RIFNB-1B TREATMENT 47
Neutralizing antibodies during treatment of relapsing Multiple Sclerosis patients with three interferon beta: correlation with clinical outcomes 47
STUDIO IN VITRO DI POPOLAZIONI LINFOMONOCITARIE CD45R+ E CD29+ 46
Modificazioni dei livelli sierici di ICAM-1 solubile (sICAM.1), e Gelatinasi A e B e sottopopolazioni T-linfocitarie di sangue periferico indotte dal trattamento con interferone-beta-1b (IFN-BETA-1B) in pazienti con Sclerosi Multipla (SM) Relapsing-Remitting (RR): Relazione con la produzione di anticorpi neutralizzanti anti-interferone (NABs) 46
B and T Immunoregulation: A New Insight of B Regulatory Lymphocytes in Autism Spectrum Disorder 46
N-Acetyl-Aspartate (NAA) and Neurofilament Light-Chain (NF-L) in Biological Fluids as Markers of Neurodegeneration in ALS 45
ADHESION MOLECULES AND MATRIX METALLOPROTEINASES IN MS: EFFECTS INDUCED BY INTERFERON BETA 45
Soluble Intercellular Adhesion Molecule-1 in serum and cerebrospinal fluid of demyelinating disease of the central and peripheral nervous system 44
IFNB-1B TREATMENT EFFECTS ON SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 SERUM LEVELS AND T-CELL SUBSETS IN RELAPSING-REMITTING MULTIPLE SCLEROSIS PATIENTS. 12TH CONGRESS OF THE EUROPEAN COMMITTE FOR TREATMENT AND RESEARCH IN MULTIPLE SCLEROSIS (ECTRIMS) 44
Interferon-b treatment in relapsing remitting multiple sclerosis: results of an observational study in southern Italy 43
ANALISI DEL POLIMORFISMO GENICO E DELLA PRODUZIONE LIMFOMONOCITARIA DI TNF-ALPHA IN PAZIENTI CON SCLEROSI MULTIPLA (SM) 43
Phenotype analysis of fresh peripheral blood, unstimulated and stimulated-cultured lymphocytes in Multiple Sclerosis (MS) with different disease course 42
SOPLUBLE INTERCELLULAR ADHESION MOLECULE-1 (SICAM-1) NEL SIERO E LIQUOR DI PAZIENTI CON SCLEROSI MULTIPLA REMITTENTE CLINICAMENTE ATTIVA: CORRELAZIONI CON LESIONI RMI CHE ASSUMONO GADOLINIO E CON PARAMETRI LIQUORALI 41
LFA-1 EXPRESSION ON CD4+CD45RO+ PERIPHERAL BLOOD T-LYMPHOCYTES: IN VIVO AND IN VITRO CHANGES INDUCED BY RECOMBINANT INTERFERON-BETA-1A (RIFN-BETA-1A) IN RELAPSING-REMITTING (RR) MULTIPLE SCLEROSIS (MS) 41
RIFN BETA-1A AND SICAM-1 EFFECTS ON CD4+CD45RO+ PBTLS EXPRESSING LFA-1 IN RR MS: IN VIVO AND IN VITRO STUDY 41
NMO-IgG and AQP-4 antibodies in different demyelinating disease phenotypes: correlations with clinical and paraclinical parameters 40
LFA-1 expressing CD4+CD45RO+ peripheral blood T-lymphocytes in RR MS: effects induced by rIFNb-1a 38
MMPS AND TIMPS ARE DIFFERENTLY RELATED TO MS COURSES AND PHASES OF THE DISEASE 37
Cerebrospinal Fluid and Clinical Profiles in Adult Type 2–3 Spinal Muscular Atrophy Patients Treated with Nusinersen: An 18-Month Single-Centre Experience 37
Bcl-2, Bax, Cytocrome-c mitochondria mediated apoptosis proteins during Glatiramer Acetate treatment in Multiple Sclerosis patients 37
VALUTAZIONE POST-MARKETING DI SICUREZZA DELL' INTERFERONE-BETA (IFN-BETA) IN PAZIENTI CON SCLEROSI MULTIPLA (SM) RELAPSING-REMITTING (RR) NELL' ITALIA MERIDIONALE. RICERCA SCIENTIFICA DELLE 36
MMPs and TIMPs involvement at the blood-brain barrier level in MS: comparison between patients enhancing with different doses of gadolinium during rIFNb-1a treatment 36
Changes of serum sICAM-1 and MMP-9 induced by rIFN beta-1b treatment in relapsing-remitting MS 36
CHANGES OF SOLUBLE INTERCELLULAR ADHESION MOLECULE-1 (SICAM-1) LEVELS INDUCED BY CORTICOSTEROIDS AND RIFN-BETA-1B IN MULTIPLE SCLEROSIS AND GUILLAIN-BARRÉ SYNDROME 34
Interferon-b treatment in relapsing remitting multiple sclerosis: results of an observational study in southern Italy 34
IN VIVO AND IN VITRO CHANGES OF LFA-1 EXPRESSION ON CD4+CD45RO+ PERIPHERAL BLOOD T-LYMPHOCYTES INDUCED BY RIFN-BETA-1A IN RELAPSING-REMITTING MULTIPLE SCLEROSIS 34
Effect of cladribine on neuronal apoptosis: New insight of in vitro study in multiple sclerosis therapy 34
Longitudinal Evaluation of Serum MOG-IgG and AQP4-IgG Antibodies in NMOSD by a Semiquantitative Ratiometric Method 34
IMMUNOPATOGENESI ED EPIDEMIOLOGIA DI PATOOGIE INFIAMMATORIE DEL SISTEMA NERVOSO PERIFERICO 33
CHANGES OF SICAM-1, TNFA AND T-CELL SUBSETS IN THE BLOOD OF MULTIPLE SCLEROSIS PATIENTS DURING RIFNB-1B TREATMENT. GRUPPO ITALIANO PER LO STUDIO DELLA NEUROMORFOLOGIA 32
EFFETTI ANTINFIAMMATORI DELL’ INTERFERONE BETA-1B RICOMBINANTE NELLA SCLEROSI MULTIPLA: STUDIO LONGITUDINALE DEI LIVELLI SIERICI DELLA FORMA SOLUBILE DI INTERCELLULAR ADHESION MOLECULE-1 (SICAM-1) E DEI SUBSETS LINFOCITARI 32
Soluble intercellular adhesion molecule-I (sICAM-I) in serum and cerebrospinal fluid of demyelinating diseases of the central and peripheral nervous system 32
Decreased levels of serum gelatinase B in MS patients during the treatment with rIFN-beta-1b 32
RELATIONSHIPS BETWEEN ANTI-RIFN-BETA 1B NEUTRALIZING ANTIBODIES (NABS) AND CHANGES OF SOLUBLE ICAM-1 AND GELATINASES A AND B SERUM LEVELS IN RIFN-BETA-1B TREATED RELAPSING REMITTING (RR) MULTIPLE SCLEROSIS (MS) 31
SERUM AND CSF CHANGES OF MATRIX METALLOPROTEINASES (MMPS) AND THEIR TISSUE INHIBITORS (TIMPS) DURING DISEASE COURSE AND INTERFERON BETA TREATMENT IN MULTIPLE SCLEROSIS (MS) 31
lesions in Multiple Sclerosis (MS) 31
Matrix metalloproteinases and disease corse in Multiple Sclerosis 31
Changes of serum soluble ICAM-1 and matrix metalloproteinas-9 (MMP-9) induced by Interferon beta-1b treatment in relapsing-remitting multiple sclerosis 30
EPIDEMIOLOGIA DELLA SCLEROSI MULTIPLA 29
Is cerebrospinal fluid amyloid-β42 a promising biomarker of response to nusinersen in adult spinal muscular atrophy patients? 29
MODIFICAZIONI DELLE SOTTOPOPOLAZIONI DI LINFOCITI T NEL SANGUE PERIFERICO ED IN COLTURA CON E SENZA AGGIUNTA DI MITOGENI IN PAZIENTI CON SCLEROSI MULTIPLA (SM) 27
Serum N-acetyl-aspartate in Relapsing Remitting Multiple Sclerosis 25
Totale 5.928
Categoria #
all - tutte 27.271
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.271


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020865 0 0 0 0 149 64 152 93 163 48 168 28
2020/2021942 95 47 92 34 111 65 108 51 93 122 83 41
2021/2022673 23 111 19 19 25 35 28 42 40 21 135 175
2022/20231.298 172 121 83 133 157 176 11 145 234 1 30 35
2023/2024391 47 70 24 24 24 90 28 21 4 10 3 46
2024/2025339 62 36 146 55 40 0 0 0 0 0 0 0
Totale 6.194