Sfoglia per Autore
Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: Synthesis and binding affinities for 5-HT7 and 5-HT1A receptors
2007-01-01 Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola Antonio; Niso, Mauro; Berardi, Francesco; Perrone, Roberto
Potential positron emission tomography radioligand for brain dopamine D3 receptor visualization: design, synthesis, binding profile, and interaction with the efflux pump P-glycoprtein.
2007-01-01 Leopoldo, Marcello; Lacivita, Enza; De Giorgio, P; Contino, Marialessandra; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, R.
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2
2007-01-01 Leopoldo, Marcello; Lacivita, Enza; Contino, Marialessandra; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto
N-[omega-[4-(2-Methoxyphenyl)-1-piperazinyl]alkyl]-2-quinolinamines as High-Affinity Fluorescent 5-HT1A Receptor Ligands
2008-01-01 Lacivita, Enza; Leopoldo, Marcello
5 HT1A receptor, an old target for new therapeutic agents
2008-01-01 Lacivita, Enza; Leopoldo, Marcello; Berardi, Francesco; Perrone, R.
Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III
2008-01-01 Leopoldo, Marcello; Lacivita, Enza; DE GIORGIO, P; Fracasso, C; Guzzetti, S; Caccia, S; Contino, Ma; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto
Determination of 1-aryl-4propylpiperazine pKa values: the substituent on aryl modulates basicity
2009-01-01 Lacivita, Enza; Leopoldo, Marcello; DE GIORGIO, P; Berardi, Francesco; Perrone, Roberto
Developments in fluorescent probes for receptor research
2009-01-01 Leopoldo, Marcello; Lacivita, Enza; Berardi, Francesco; Perrone, Roberto
Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands with optimal lipophilicity for brain imaging of the dopamine D3 receptor. Part II
2009-01-01 Leopoldo, Marcello; Lacivita, Enza; DE GIORGIO, P; Contino, Marialessandra; Berardi, Francesco; Perrone, Roberto
Synthesis and characterization of enviroment-sensitive fluorescent ligands for human 5-HT1a receptor with 1.arylpiperazine structure
2009-01-01 Lacivita, Enza; Leopoldo, Marcello; Masotti, Ac; Inglese, C; Berardi, Francesco; Perrone, Roberto; Ganguly, S; Jafurulla, M; Chattopadhay,
Design, synthesis, radiolabeling and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential Positron Emission Tomography tracer for the dopamine D4 receptors
2010-01-01 Lacivita, Enza; DE GIORGIO, P; Lee, I. T.; Rodeheaver, S. I.; Weiss, B. A.; Fracasso, C; Caccia, S; Berardi, Francesco; Perrone, Roberto; Zhang, M. R.; Maeda, J; Higuchi, M; Suhara, T; Schetz, J. A.; Leopoldo, Marcello
Identification of a red-emitting fluorescent ligand suitable for in vitro 5-HT1A receptor visualization
2010-01-01 Lacivita, E; Masotti, A. C.; Jafurulla, Md; Saxena, R; Rangaraj, N; Chattopadhyay, A; Colabufo, Na; Berardi, F; Perrone, R; Leopoldo, M
5-HT7 receptor modulators: a medicinal chemistry survey of recent patent literature (2004 - 2009)
2010-01-01 Leopoldo, Marcello; Lacivita, Enza; Berardi, Francesco; Perrone, Roberto
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor
2010-01-01 Hedlund, Pb; Leopoldo, Marcello; Caccia, S; Sarkisyan, G; Fracasso, C; Martelli, G; Lacivita, Enza; Berardi, Francesco; Perrone, Roberto
The medicinal chemistry of 5-HT2C receptor ligands
2011-01-01 Leopoldo, Marcello; Lacivita, Enza; DE GIORGIO, P; Berardi, Francesco; Perrone, Roberto
Selective serotonergic 5-HT7 receptor agonists as a new therapeutic venue for treatment of cognitive disorders: focus on Fragile X syndrome.
2011-01-01 Lacivita, Enza; De Giorgio, P; Ciranna, L; Costa, L; Berardi, Francesco; Perrone, R; Leopoldo, Marcello
New 1-arylpiperazinic ligands of 5-HT7 receptor and use thereof
2011-01-01 Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola Antonio; De Giorgio, P; Berardi, Francesco; Perrone, Roberto
Development of a PET radioligand for the 5-HT7 receptor. Preliminary characterization using autoradiography
2011-01-01 Andersson, Jd; Leopoldo, Marcello; Lacivita, Enza; De Giorgio, P; Krasikova, R; Varnas, K; Halldin, C.
Serotonin 5-HT7 receptor agents: structure-activity relationships and potential therapeutic applications in central nervous system disorders
2011-01-01 Leopoldo, Marcello; Lacivita, Enza; Berardi, Francesco; Perrone, Roberto; Hedlund, Pb
Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto
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