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Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers 1-gen-2011 Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto
Increase of Capsaicin-Induced Trigeminal Fos-Like Immunoreactivity by 5-HT(7) Receptors. 1-gen-2011 Martínez García, E; Leopoldo, Marcello; Lacivita, Enza; Terrón, J. A.
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X Syndrome 1-gen-2012 Costa, L; Spatuzza, M; D'Antoni, S; Bonaccorso, Cm; Trovato, C; Musumeci, Sa; Leopoldo, Marcello; Lacivita, Enza; Catania, Mv; Ciranna, L.
Fluorescent probes: from bench to bedside 1-gen-2012 Lacivita, Enza; Leopoldo, Marcello
POLYCYCLIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF 1-gen-2012 Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola Antonio; De Giorgio, Paola; Berardi, Francesco; Perrone, Roberto
Investigations on the 1-(2-biphenyl)piperazine motif. Identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo. 1-gen-2012 Lacivita, Enza; Patarnello, D; Stroth, N; Caroli, A; Niso, Mauro; Contino, Marialessandra; De Giorgio, P; Di Pilato, P; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, R; Svenningsson, P; Hedlund, Pb; Leopoldo, Marcello
Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice 1-gen-2012 Adriani, W; Travaglini, D; Lacivita, Enza; Saso, L; Leopoldo, Marcello; Laviola, G.
The therapeutic potential of 5-HT1A receptors: a patent review. 1-gen-2012 Lacivita, Enza; Di Pilato, P; De Giorgio, P; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Leopoldo, Marcello
Activatable fluorescent probes: a new concept in optical molecular imaging 1-gen-2012 Lacivita, Enza; Leopoldo, Marcello; Berardi, Francesco; Colabufo, Nicola Antonio; Perrone, R.
PREVENTION AND TREATMENT OF RETT SYNDROME 1-gen-2013 Laviola, G; De Filippis, B; Adriani, W; Lacivita, Enza; Leopoldo, Marcello
Design, synthesis, radiolabeling and in vivo biological evaluation of potential 5-Ht7 receptor PET tracers: Structural modifications of the selective agonist Lp-211 1-gen-2013 Di Pilato, P; Herth, Mm; Hansen, Hd; Lehel, S; Lacivita, Enza; Andersen, Vl; Dyssegaard, A; Ettrup, A; Madsen, J; Perrone, R; Leopoldo, Marcello; Knudsen, Gm
The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling. 1-gen-2013 Atanes, P; Lacivita, Enza; Rodríguez, J; Brea, J; Burgueño, J; Vela, Jm; Cadavid, Mi; Loza, Mi; Leopoldo, Marcello; Castro, M.
Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters 1-gen-2013 Lacivita, Enza; De Giorgio, P; Patarnello, D; Niso, Mauro; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Satala, G; Duszynska, B; Bojarski, Aj; Leopoldo, Marcello
Novel highly potent serotonin 5-HT7 receptor ligands: structural modifications to improve pharmacokinetic properties 1-gen-2013 Lacivita, Enza; Di Pilato, P; Stama, Ml; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; De Filippis, B; Laviola, G; Adriani, W; Niso, Mauro; Leopoldo, Marcello
3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: Molecular modeling of chiral recognition by FPR2. 1-gen-2013 Schepetkin, Ia; Kirpotina, Ln; Khlebnikov, Ai; Leopoldo, Marcello; Lucente, E; Lacivita, Enza; De Giorgio, P; Quinn, M. T.
THE ARYLPIPERAZINE DERIVATIVES LP-211 AND MEL-9 ARE INACTIVATING ANTAGONISTS AT HUMAN SEROTONIN 5-HT7 RECEPTORS 1-gen-2013 Atanes, P; Lacivita, Enza; Rodriguez, J; Brea, J; Cadavid, Mi; Loza, Mi; Leopoldo, Marcello; Castro, M.
Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study. 1-gen-2014 Altabella, L; Sbriccoli, M; Zoratto, F; Poleggi, A; Vinci, R; Lacivita, Enza; Leopoldo, Marcello; Laviola, G; Cardone, F; Canese, R; Adriani, W.
Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome. 1-gen-2014 De Filippis, B; Nativio, P; Fabbri, A; Ricceri, L; Adriani, W; Lacivita, Enza; Leopoldo, Marcello; Passarelli, F; Fuso, A; Laviola, G.
Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview. 1-gen-2014 Di Pilato, P; Niso, Mauro; Adriani, W; Romano, E; Travaglini, D; Berardi, Francesco; Colabufo, Nicola Antonio; Perrone, Roberto; Laviola, G; Lacivita, Enza; Leopoldo, Marcello
Synthesis, radiolabeling and in vivo evaluation of [11C](R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7 receptor 1-gen-2014 Hansen, Hd; Lacivita, Enza; Di Pilato, P; Herth, Mm; Lehel, S; Ettrup, A; Andersen, Vl; Dyssegaard, A; De Giorgio, P; Perrone, Roberto; Berardi, F; Colabufo, Nicola Antonio; Mauro, N; Knudsen, Gm; Leopoldo, Marcello
Mostrati risultati da 41 a 60 di 126
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