Hospital, Bari, Italy, for respiratory distress after a 3 months history of chronic cough. The cat was born and lived in UK until it was moved to Italy 4 months before the clinical signs started. Alveolar-interstitial patterns with air bronchogram in the caudal edge of the right cranial and middle lung lobes were revealed by radiographic and ultrasonographic thoracic evaluations. Sub-pleural lung consolidations were also observed. A computed tomography scan confirmed the previous findings, revealing also the presence of multiple non-defined nodules in both hemithoraces. Bronchoscopy and bronchoalveolar lavage were performed and the cytologic exam showed a neutrophilic inflammation with many activated macrophages (dust cells). Ultrasound-guided fine needle aspirations from the left subpleural consolidations were subjected to analysis for aerobial/anaerobial bacteria, for mycoplasmas and fungal infections, using standard cultural methods. FNAs and blood samples were also screened for Chlamydia spp, Mycobacterium spp., FeCV, FeHV, FIV and FeLV by using molecular methods. Mycobacterium lepraemurium infection was diagnosed in FNA samples based on sequence of a 550 bp fragment encompassing the V2V3 hypervariable region of the 16S rRNA gene. Samples tested negative for other targets. The cat is currently being treated with doxycycline, pradofloxacin and clarithromycin, at 10 mg/Kg once daily, 4.5 mg/Kg once daily, and 9 mg/Kg twice daily, respectively. This report describes a pulmonary localization of Mycobacterium lepraemurium in a cat, in the absence of skin lesions.
Pneumonia Associated with Mycobacterium lepraemurium In A 4-Year-Old Cat: A Case Report
Decaro N.;Greco G.
2019-01-01
Abstract
Hospital, Bari, Italy, for respiratory distress after a 3 months history of chronic cough. The cat was born and lived in UK until it was moved to Italy 4 months before the clinical signs started. Alveolar-interstitial patterns with air bronchogram in the caudal edge of the right cranial and middle lung lobes were revealed by radiographic and ultrasonographic thoracic evaluations. Sub-pleural lung consolidations were also observed. A computed tomography scan confirmed the previous findings, revealing also the presence of multiple non-defined nodules in both hemithoraces. Bronchoscopy and bronchoalveolar lavage were performed and the cytologic exam showed a neutrophilic inflammation with many activated macrophages (dust cells). Ultrasound-guided fine needle aspirations from the left subpleural consolidations were subjected to analysis for aerobial/anaerobial bacteria, for mycoplasmas and fungal infections, using standard cultural methods. FNAs and blood samples were also screened for Chlamydia spp, Mycobacterium spp., FeCV, FeHV, FIV and FeLV by using molecular methods. Mycobacterium lepraemurium infection was diagnosed in FNA samples based on sequence of a 550 bp fragment encompassing the V2V3 hypervariable region of the 16S rRNA gene. Samples tested negative for other targets. The cat is currently being treated with doxycycline, pradofloxacin and clarithromycin, at 10 mg/Kg once daily, 4.5 mg/Kg once daily, and 9 mg/Kg twice daily, respectively. This report describes a pulmonary localization of Mycobacterium lepraemurium in a cat, in the absence of skin lesions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
