Aim of this project is the synthesis and characterization of nanostructured drug delivery systems (DDS) to be used in the therapy of urinary tract affections. The main idea is based on the synthesis of a bioconjugate between inulin and vitamin E (INVITE) able to produce amphiphilic systems self-assembling in nanostructured DDS even at low concentrations. A so ideated system should solubilize, incorporate and protect lipophilic drugs while targeting them in the urinary tract [1,2].
NEW NANOSTRUCTURED SELF-ASSEMBLING INULIN-α-TOCOPHEROL BIOCONJUGATES FOR BIOMEDICAL APPLICATION
MANDRACCHIA, DELIA;CUTRIGNELLI, ANNALISA;LAQUINTANA, VALENTINO;DENORA, NUNZIO;LOPEDOTA, Angela Assunta;FRANCO, Massimo;
2012-01-01
Abstract
Aim of this project is the synthesis and characterization of nanostructured drug delivery systems (DDS) to be used in the therapy of urinary tract affections. The main idea is based on the synthesis of a bioconjugate between inulin and vitamin E (INVITE) able to produce amphiphilic systems self-assembling in nanostructured DDS even at low concentrations. A so ideated system should solubilize, incorporate and protect lipophilic drugs while targeting them in the urinary tract [1,2].File in questo prodotto:
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