IRIS
BRUNETTI, LEONARDO
 Distribuzione geografica
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Continente #
NA - Nord America 2.096
AS - Asia 1.344
EU - Europa 1.129
SA - Sud America 307
Continente sconosciuto - Info sul continente non disponibili 196
AF - Africa 66
OC - Oceania 3
Totale 5.141
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Nazione #
US - Stati Uniti d'America 2.015
SG - Singapore 538
IT - Italia 426
BR - Brasile 254
CN - Cina 254
RU - Federazione Russa 161
HK - Hong Kong 157
DE - Germania 104
SE - Svezia 102
VN - Vietnam 98
FR - Francia 89
IN - India 84
GB - Regno Unito 71
BD - Bangladesh 43
CA - Canada 41
AT - Austria 38
FI - Finlandia 28
JP - Giappone 28
ID - Indonesia 27
PL - Polonia 21
AR - Argentina 19
TR - Turchia 19
TW - Taiwan 18
MX - Messico 17
NL - Olanda 16
ZA - Sudafrica 15
CI - Costa d'Avorio 14
BE - Belgio 12
IQ - Iraq 11
CO - Colombia 10
EC - Ecuador 10
LT - Lituania 10
ES - Italia 9
MA - Marocco 9
AL - Albania 8
KE - Kenya 8
KR - Corea 8
CH - Svizzera 6
PH - Filippine 6
AE - Emirati Arabi Uniti 5
CL - Cile 5
MY - Malesia 5
UA - Ucraina 5
CR - Costa Rica 4
CZ - Repubblica Ceca 4
EE - Estonia 4
EG - Egitto 4
OM - Oman 4
SA - Arabia Saudita 4
AU - Australia 3
AZ - Azerbaigian 3
BH - Bahrain 3
DK - Danimarca 3
IL - Israele 3
JM - Giamaica 3
LB - Libano 3
PA - Panama 3
PK - Pakistan 3
PY - Paraguay 3
TT - Trinidad e Tobago 3
UZ - Uzbekistan 3
VE - Venezuela 3
BY - Bielorussia 2
HN - Honduras 2
IE - Irlanda 2
KG - Kirghizistan 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NG - Nigeria 2
NP - Nepal 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
ZW - Zimbabwe 2
AO - Angola 1
BB - Barbados 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BO - Bolivia 1
CG - Congo 1
CV - Capo Verde 1
DM - Dominica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
GI - Gibilterra 1
GP - Guadalupe 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LV - Lettonia 1
MR - Mauritania 1
NI - Nicaragua 1
NO - Norvegia 1
PE - Perù 1
Totale 4.937
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Città #
Singapore 298
Ashburn 277
San Jose 212
Chandler 174
Hong Kong 141
Milan 98
Nyköping 96
Beijing 93
Council Bluffs 87
Fairfield 81
Dallas 61
Los Angeles 52
Cambridge 51
New York 47
Bari 40
Houston 40
Santa Clara 39
Seattle 39
Naples 37
Ho Chi Minh City 34
Munich 34
Rome 34
Woodbridge 31
Lauterbourg 28
Wilmington 28
Jakarta 25
Helsinki 24
Tokyo 24
Hanoi 23
Frankfurt am Main 22
Moscow 22
Chicago 21
Langenzersdorf 21
Lawrence 21
Falkenstein 20
Fragagnano 20
North Bergen 20
São Paulo 20
Roxbury 19
London 17
Marseille 17
Brooklyn 16
Inglewood 16
Atlanta 15
Columbus 15
Warsaw 15
Abidjan 14
Boardman 13
Montreal 13
San Francisco 13
Ann Arbor 12
Buffalo 12
Denver 12
Poplar 12
Brussels 11
Chennai 11
Johannesburg 11
Nuremberg 11
Phoenix 11
Boydton 10
Kolkata 10
Orem 10
Bologna 9
Des Moines 9
Paris 9
Redondo Beach 9
Rio de Janeiro 9
Toronto 9
Düsseldorf 7
Figino 7
Guangzhou 7
Nairobi 7
Patna 7
Salt Lake City 7
Shanghai 7
Vienna 7
Amsterdam 6
Boston 6
Mexico City 6
Tirana 6
Wuxi 6
Baghdad 5
Bitonto 5
Brasília 5
Brindisi 5
Dong Ket 5
Draper 5
Elk Grove Village 5
Florence 5
Las Vegas 5
Molfetta 5
New Delhi 5
Portsmouth 5
Shenzhen 5
Taichung 5
Taipei 5
Washington 5
Ankara 4
Belo Horizonte 4
Buenos Aires 4
Totale 2.983
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Nome #
DEVELOPMENT OF PHENOXYALKYLPIPERIDINES AS HIGH-AFFINITY SIGMA-1 (s1) RECEPTOR LIGANDS WITH POTENT ANTI-AMNESIC ACTIVITY 195
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 175
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 169
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 163
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 163
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation 149
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 149
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 141
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 141
A Chemical Modification of a Peroxisome Proliferator-Activated Receptor Pan Agonist Produced a Shift to a New Dual Alpha/Gamma Partial Agonist Endowed with Mitochondrial Pyruvate Carrier Inhibition and Antidiabetic Properties 137
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 133
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 131
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 129
(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 126
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases 124
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 122
Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases 120
Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey 119
Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect 118
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 112
FPR2 and brimstone: a novel approach for the treatment of neuroinflammation 112
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 106
Rivastigmine structure-based hybrids as potential multi-target anti-Alzheimer’s drug candidates 105
Novel Phenothiazine/Donepezil-Like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer’s Disease 104
Natural compounds as FAAH inhibitors: preliminary screening and potential developments 104
Can foods influence the onset and progress of neurodegenerative diseases? 101
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 100
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease 99
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 95
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy 92
Novel small molecules for PPARs modulation and their potential use for treatment of metabolic disorders 87
Multiple causes, multiple targets: FAAH as a centerpiece for therapy of multifactorial pathologies. 84
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ 83
Multi-Target Approach for the Design of New Compounds Potentially Useful for the Prevention and Treatment of Cardiovascular and/or Neurodegenerative Diseases 82
Role of copper chelating agents: between old applications and new perspectives in neuroscience 80
Peroxisome Proliferator Activated Receptor (PPAR) agonists as Fatty Acid Amide Hydrolase (FAAH) inhibitors: screening and preliminary structure-activity relationships 80
Discovery of a dual PPARα/γ partial agonist displaying antisteatotic and antidiabetic properties: in silico studies and X-ray structure determination 74
From classical MTDLs to a semi-synthetic innovative green approach: nature-inspired design as a new intriguing opportunity for new anti-Alzheimer’s drugs 74
New rivastigmine-like compounds for the potential treatment of Alzheimer’s disease: a multi-target approach 64
Design, Synthesis, and Biological Evaluation of Novel Heteroaryl, Squaramide, and Indolcarboxamide Derivatives as Formyl Peptide Receptor 2 Agonists to Target Neuroinflammation 61
Rivastigmine-based hybrids: a multi-target approach to anti-Alzheimer’s drug design 58
The pivotal role of pyrrolidine ring as multitarget scaffold in neurodegenerative diseases 55
Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer’s Disease 54
New phenothiazine-donepezil like hybrids as potential Alzheimer’s disease multitarget drugs with antioxidant properties 54
Tackling neuroinflammation with H2S releasing FPR2 agonists 51
Rivastigmine-Benzimidazole Hybrids as Promising Multitarget Metal-Modulating Compounds for Potential Treatment of Neurodegenerative Diseases 45
A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse model 42
Novel Rivastigmine-Based Multitarget Hybrids For Potential Treatment of Alzheimer’s Disease: Cu(II) And Fe(III) Chelation Studies 36
Multitarget 5-HT6R/FAAH/ChE ligands: the future of Alzheimer’s Disease treatment? 36
Novel rivastigmine structure-based hybrids for the potential treatment of Alzheimer’s disease 34
The first-in-class 1,3,5-triazine-derived dual 5-HT6R/FAAH modulators in search for potential drug against neurodegenerative diseases with cognitive impairment 24
Hydrogen Sulfide (H2S)-Donating Formyl Peptide Receptor 2 (FPR2) Agonists: Design, Synthesis, and Biological Evaluation in Primary Mouse Microglia Culture 21
Beyond Radical Scavengers: Focus on NADPH Oxidases (NOX) Inhibitors as New Agents for Antioxidant Therapy in Alzheimer’s Disease 15
A Holistic Approach to Identifying a Positron Emission Tomography (PET) Tracer Candidate for In Vivo Imaging of Purinergic P2X7 Receptor in Neuroinflammation 10
New chalcogen-optimized 1,3,5-triazines as dual 5-HT6R/FAAH modulators: A versatile approach to neurodegenerative disorders 3
Totale 5.141
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Categoria #
all - tutte 20.976
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.976
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022136 0 0 2 1 0 13 3 5 13 14 26 59
2022/2023418 33 61 36 33 32 52 7 57 68 9 19 11
2023/2024241 14 22 15 12 21 56 12 2 17 23 17 30
2024/20251.176 79 42 70 63 53 63 173 120 69 80 124 240
2025/20262.559 331 155 173 295 272 128 262 130 270 251 126 166
2026/2027236 75 94 67 0 0 0 0 0 0 0 0 0
Totale 5.141