BRUNETTI, LEONARDO

BRUNETTI, LEONARDO  

DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO  

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(2-Aminobenzothiazole)-Methyl-1,1-bisphosphonic acids: Targeting matrix metalloproteinase 13 inhibition to the bone 1-gen-2021 Laghezza, A.; Piemontese, L.; Brunetti, L.; Caradonna, A.; Agamennone, M.; Loiodice, F.; Tortorella, P.
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease 1-gen-2022 Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga
A Chemoinformatics Search for Peroxisome Proliferator-Activated Receptors Ligands Revealed a New Pan-Agonist Able to Reduce Lipid Accumulation and Improve Insulin Sensitivity 1-gen-2022 Sblano, S.; Cerchia, C.; Laghezza, A.; Piemontese, L.; Brunetti, L.; Leuci, R.; Gilardi, F.; Thomas, A.; Genovese, M.; Santi, A.; Tortorella, P.; Paoli, P.; Lavecchia, A.; Loiodice, F.
A NEW ANTIDIABETIC AGENT SHOWING PPARα/γ DUAL AGONISM AND MITOCHONDRIAL PYRUVATE CARRIER INHIBITION 1-gen-2023 Cerchia, C.; Laghezza, A.; Genovese, M.; Leuci, R.; Pranzini, E.; Santi, A.; Brunetti, L.; Piemontese, L.; Tortorella, P.; Biswas, A.; Singh, R. P.; Tambe, S.; Ca, S.; Pattnaik, A. K.; Jayaprakash, V.; Paoli, P.; Loiodice, F.; Lavecchia, A.
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 1-gen-2023 Laghezza, Antonio; Cerchia, Carmen; Genovese, Massimo; Leuci, Rosalba; Pranzini, Erica; Santi, Alice; Brunetti, Leonardo; Piemontese, Luca; Tortorella, Paolo; Biswas, Abanish; Pratap Singh, Ravi; Tambe, Suhas; Ca, Sudeep; Kumar Pattnaik, Ashok; Jayaprakash, Venkatesan; Paoli, Paolo; Lavecchia, Antonio; Loiodice, Fulvio
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 1-gen-2022 Leuci, R.; Brunetti, L.; Laghezza, A.; Piemontese, L.; Carrieri, A.; Pisani, L.; Tortorella, P.; Catto, M.; Loiodice, F.
A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders 1-gen-2020 Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Tortorella, Paolo; Loiodice, Fulvio; Piemontese, Luca
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors 1-gen-2020 Brunetti, Leonardo; Carrieri, Antonio; Piemontese, Luca; Tortorella, Paolo; Loiodice, Fulvio; Laghezza, Antonio
Bone-seeking matrix metalloproteinase inhibitors for the treatment of skeletal malignancy 1-gen-2020 Laghezza, A.; Piemontese, L.; Brunetti, L.; Caradonna, A.; Agamennone, M.; Di Pizio, A.; Pochetti, G.; Montanari, R.; Capelli, D.; Tauro, M.; Loiodice, F.; Tortorella, P.
Can foods influence the onset and progress of neurodegenerative diseases? 1-gen-2022 Piemontese, Luca; Brunetti, Leonardo; Leuci, Rosalba
Combining fatty acid amide hydrolase (FAAH) inhibition with peroxisome proliferator-activated receptor (PPAR) activation: a new potential multi-target therapeutic strategy for the treatment of Alzheimer’s disease 1-gen-2020 Brunetti, Leonardo; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Piemontese, Luca
Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2‐Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil‐Like Compounds 1-gen-2020 Piemontese, L.; Sergio, R.; Rinaldo, F.; Brunetti, L.; Perna, F. M.; Amelia Santos, M.; Capriati, V.
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents 1-gen-2021 Poliseno, Viviana; Chaves, Sílvia; Brunetti, Leonardo; Loiodice, Fulvio; Carrieri, Antonio; Laghezza, Antonio; Tortorella, Paolo; Magalhães, João D.; Cardoso, Sandra M.; Santos, M. Amélia; Piemontese, Luca
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 1-gen-2023 Intranuovo, Francesca; Brunetti, Leonardo; Delre, Pietro; Mangiatordi, Giuseppe Felice; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Isabel Loza, Maria; Sotelo, Eddy; Saviano, Michele; Colabufo, Nicola Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra
Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect 1-gen-2022 Abatematteo, F. S.; Mosier, P. D.; Niso, M.; Brunetti, L.; Berardi, F.; Loiodice, F.; Contino, M.; Delprat, B.; Maurice, T.; Laghezza, A.; Abate, C.
DEVELOPMENT OF PHENOXYALKYLPIPERIDINES AS HIGH-AFFINITY SIGMA-1 (s1) RECEPTOR LIGANDS WITH POTENT ANTI-AMNESIC ACTIVITY 1-gen-2021 Laghezza, Antonio; Abatematteo, Francesca S.; Mosier, Philip D.; Niso, Mauro; Brunetti, Leonardo; Berardi, Francesco; Loiodice, Fulvio; Contino, Marialessandra; Delprat, Benjamin; Maurice, Tangui; Abate, Carmen
Food Industry Byproducts as Starting Material for Innovative, Green Feed Formulation: A Sustainable Alternative for Poultry Feeding 1-gen-2022 Brunetti, Leonardo; Leuci, Rosalba; Colonna, Maria Antonietta; Carrieri, Rossana; Celentano, Francesco Emanuele; Bozzo, Giancarlo; Loiodice, Fulvio; Selvaggi, Maria; Tufarelli, Vincenzo; Piemontese, Luca
IDENTIFICATION OF A NOVEL PPARRα/γ DUAL AGONIST SHOWING ANTIDIABETIC EFFECTS AND ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF ABLE TO BIND TO CANONICAL AND ALLOSTERIC SITES OF PPARγ 1-gen-2023 Laghezza, A.; Brunetti, L.; Leuci, R.; Tortorella, P.; Piemontese, L.; Paoli, P.; Jayaprakash, V.; Cerchia, C.; Lavecchia, A.; Loiodice, F.
Identification of Natural Scaffolds as New Multi-Functional Agents for the Treatment of Alzheimer’s Disease 1-gen-2019 Laghezza, Antonio; Brunetti, Leonardo; Capriati, Vito; Catto, Marco; Loiodice, Fulvio; Tortorella, Paolo; Piemontese, Luca; Solfrizzo, Michele
Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents 1-gen-2020 Leuci, Rosalba; Brunetti, Leonardo; Laghezza, Antonio; Loiodice, Fulvio; Tortorella, Paolo; Piemontese, Luca