DE CANDIA, MODESTO
DE CANDIA, MODESTO
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease
2022-01-01 Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga
2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity
2012-01-01 Soto Otero, R; Mendez Alvarez, E; Sanchez Iglesias, S; Labandeira Garcıa, Jl; Rodrıguez Pallares, J; Zubkov, Fi; Zaytsev, Vp; Voskressensky, Lg; Varlamov, Av; DE CANDIA, Modesto; Fiorella, F; Altomare, Cosimo Damiano
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance
2019-01-01 Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease.
2021-01-01 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics
2024-01-01 Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano
A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles
2017-01-01 Parisi, Giovanna; Degennaro, Leonardo; Carlucci, Claudia; DE CANDIA, Modesto; Mastrorilli, Pietro; Roller, A; Holzer, W; Altomare, Cosimo Damiano; Pace, V; Luisi, Renzo
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells
2018-01-01 Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease
2019-01-01 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
A second life for MAO inhibitors? From CNS diseases to anticancer therapy
2024-01-01 Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads.
2019-01-01 Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G.
Anticoagulant activity of new glycoconjugated inhibitors Of factor Xa and thrombin
2015-01-01 DE CANDIA, Modesto; Zaetta, Giorgia; Denora, Nunzio; Cellamare, Saverio; Altomare, Cosimo Damiano
Antiplatelet 2-Hydroxy Thienopyridine Ester Derivatives for the Reduction of Thrombotic Cardiovascular Events
2016-01-01 DE CANDIA, Modesto; Denora, Nunzio; Altomare, Cosimo Damiano
Antiplatelet activity of nipecotic acid derivatives
1999-01-01 Altomare, C.; Cellamare, Saverio; Summo, L.; DE CANDIA, Modesto; Campagna, F.; Ferappi, M.; Carotti, A.
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
2022-01-01 Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D.
Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents
2021-01-01 Titov, Alexander A; Kobzev, Maxim S; Catto, Marco; Candia, Modesto de; Gambacorta, Nicola; Denora, Nunzio; Pisani, Leonardo; Nicolotti, Orazio; Borisova, Tatiana N; Varlamov, Alexey V; Voskressensky, Leonid G; Altomare, Cosimo D
AZEPINO [4,3-b]INDOLE DERIVATIVES AS SELECTIVE INHIBITORS OF HUMAN BUTYRYLCHOLINESTERASE WITH PROTECTIVE EFFECTS AGAINST NMDA-INDUCED NEUROTOXICITY
2016-01-01 DE CANDIA, Modesto; Denora, Nunzio; Majellaro, Maria; Cellamare, Saverio; Altomare, Cosimo Damiano
Benzyloxyanilides of nipecotic acids with dual antithrombotic effects: inhibition of coagulative serine proteases and antiplatelet activity
2007-01-01 DE CANDIA, Modesto; Carotti, A; Liantonio, F; DE CRISTOFARO, R; Altomare, Cosimo Damiano
beta-D-glucosyl conjugates of highly potent inhibitors of blood coagulation factor Xa bearing 2-chlorothiophene as a P1 motif
2012-01-01 Lopopolo, G; DE CANDIA, Modesto; Panza, L; Romano, M. R.; Lograno, Marcello Diego; Campagna, F; Altomare, Cosimo Damiano
Biarylmethoxy isonipecotanilides as potent and selective inhibitors of blood coagulation factor Xa
2011-01-01 Lopopolo, G; Fiorella, F; DE CANDIA, Modesto; Nicolotti, Orazio; Martel, S; Carrupt, P. A.; Altomare, Cosimo Damiano
Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones
2019-01-01 Rullo, Mariagrazia; Catto, Marco; Carrieri, Antonio; de Candia, Modesto; Altomare, Cosimo damiano; Pisani, Leonardo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease | 1-gen-2022 | Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga | |
| 2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity | 1-gen-2012 | Soto Otero, R; Mendez Alvarez, E; Sanchez Iglesias, S; Labandeira Garcıa, Jl; Rodrıguez Pallares, J; Zubkov, Fi; Zaytsev, Vp; Voskressensky, Lg; Varlamov, Av; DE CANDIA, Modesto; Fiorella, F; Altomare, Cosimo Damiano | |
| 3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance | 1-gen-2019 | Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D. | |
| 3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. | 1-gen-2021 | Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D. | |
| A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics | 1-gen-2024 | Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano | |
| A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles | 1-gen-2017 | Parisi, Giovanna; Degennaro, Leonardo; Carlucci, Claudia; DE CANDIA, Modesto; Mastrorilli, Pietro; Roller, A; Holzer, W; Altomare, Cosimo Damiano; Pace, V; Luisi, Renzo | |
| A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells | 1-gen-2018 | Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G. | |
| A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease | 1-gen-2019 | Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M | |
| A second life for MAO inhibitors? From CNS diseases to anticancer therapy | 1-gen-2024 | Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D. | |
| Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. | 1-gen-2019 | Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G. | |
| Anticoagulant activity of new glycoconjugated inhibitors Of factor Xa and thrombin | 1-gen-2015 | DE CANDIA, Modesto; Zaetta, Giorgia; Denora, Nunzio; Cellamare, Saverio; Altomare, Cosimo Damiano | |
| Antiplatelet 2-Hydroxy Thienopyridine Ester Derivatives for the Reduction of Thrombotic Cardiovascular Events | 1-gen-2016 | DE CANDIA, Modesto; Denora, Nunzio; Altomare, Cosimo Damiano | |
| Antiplatelet activity of nipecotic acid derivatives | 1-gen-1999 | Altomare, C.; Cellamare, Saverio; Summo, L.; DE CANDIA, Modesto; Campagna, F.; Ferappi, M.; Carotti, A. | |
| Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases | 1-gen-2022 | Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D. | |
| Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents | 1-gen-2021 | Titov, Alexander A; Kobzev, Maxim S; Catto, Marco; Candia, Modesto de; Gambacorta, Nicola; Denora, Nunzio; Pisani, Leonardo; Nicolotti, Orazio; Borisova, Tatiana N; Varlamov, Alexey V; Voskressensky, Leonid G; Altomare, Cosimo D | |
| AZEPINO [4,3-b]INDOLE DERIVATIVES AS SELECTIVE INHIBITORS OF HUMAN BUTYRYLCHOLINESTERASE WITH PROTECTIVE EFFECTS AGAINST NMDA-INDUCED NEUROTOXICITY | 1-gen-2016 | DE CANDIA, Modesto; Denora, Nunzio; Majellaro, Maria; Cellamare, Saverio; Altomare, Cosimo Damiano | |
| Benzyloxyanilides of nipecotic acids with dual antithrombotic effects: inhibition of coagulative serine proteases and antiplatelet activity | 1-gen-2007 | DE CANDIA, Modesto; Carotti, A; Liantonio, F; DE CRISTOFARO, R; Altomare, Cosimo Damiano | |
| beta-D-glucosyl conjugates of highly potent inhibitors of blood coagulation factor Xa bearing 2-chlorothiophene as a P1 motif | 1-gen-2012 | Lopopolo, G; DE CANDIA, Modesto; Panza, L; Romano, M. R.; Lograno, Marcello Diego; Campagna, F; Altomare, Cosimo Damiano | |
| Biarylmethoxy isonipecotanilides as potent and selective inhibitors of blood coagulation factor Xa | 1-gen-2011 | Lopopolo, G; Fiorella, F; DE CANDIA, Modesto; Nicolotti, Orazio; Martel, S; Carrupt, P. A.; Altomare, Cosimo Damiano | |
| Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones | 1-gen-2019 | Rullo, Mariagrazia; Catto, Marco; Carrieri, Antonio; de Candia, Modesto; Altomare, Cosimo damiano; Pisani, Leonardo |