IRIS
NATILE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 20.818
AS - Asia 6.370
EU - Europa 5.824
SA - Sud America 1.709
Continente sconosciuto - Info sul continente non disponibili 459
AF - Africa 233
OC - Oceania 19
Totale 35.432
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Nazione #
US - Stati Uniti d'America 20.367
SG - Singapore 2.494
CN - Cina 1.781
IT - Italia 1.574
BR - Brasile 1.344
RU - Federazione Russa 1.253
SE - Svezia 819
HK - Hong Kong 770
UA - Ucraina 455
DE - Germania 398
FI - Finlandia 394
VN - Vietnam 357
FR - Francia 321
GB - Regno Unito 273
IN - India 190
CA - Canada 174
BD - Bangladesh 154
AR - Argentina 108
IQ - Iraq 86
CO - Colombia 73
ID - Indonesia 67
TR - Turchia 65
MX - Messico 62
EC - Ecuador 58
ZA - Sudafrica 55
SA - Arabia Saudita 53
VE - Venezuela 49
BE - Belgio 47
PK - Pakistan 46
JP - Giappone 45
ES - Italia 44
IE - Irlanda 44
CI - Costa d'Avorio 41
CR - Costa Rica 41
PL - Polonia 40
NL - Olanda 31
MA - Marocco 30
UZ - Uzbekistan 29
MY - Malesia 26
PH - Filippine 26
CL - Cile 25
AT - Austria 24
GT - Guatemala 24
IL - Israele 24
TN - Tunisia 22
HN - Honduras 21
KZ - Kazakistan 21
NI - Nicaragua 21
SV - El Salvador 21
CZ - Repubblica Ceca 19
GP - Guadalupe 19
LT - Lituania 19
JM - Giamaica 18
KE - Kenya 18
IR - Iran 17
TT - Trinidad e Tobago 17
AU - Australia 16
CW - ???statistics.table.value.countryCode.CW??? 16
JO - Giordania 16
PY - Paraguay 16
SC - Seychelles 16
AE - Emirati Arabi Uniti 14
BO - Bolivia 14
PR - Porto Rico 12
AZ - Azerbaigian 11
OM - Oman 11
DZ - Algeria 10
EG - Egitto 10
PE - Perù 10
ET - Etiopia 9
UY - Uruguay 9
NG - Nigeria 8
PT - Portogallo 8
HR - Croazia 7
HU - Ungheria 7
NP - Nepal 7
TH - Thailandia 7
AL - Albania 6
EE - Estonia 6
PA - Panama 6
PS - Palestinian Territory 6
SY - Repubblica araba siriana 6
BG - Bulgaria 5
BH - Bahrain 5
DO - Repubblica Dominicana 5
LB - Libano 5
LK - Sri Lanka 5
RS - Serbia 5
SK - Slovacchia (Repubblica Slovacca) 5
GE - Georgia 4
GR - Grecia 4
KG - Kirghizistan 4
DM - Dominica 3
EU - Europa 3
KR - Corea 3
RO - Romania 3
SN - Senegal 3
AM - Armenia 2
CG - Congo 2
CH - Svizzera 2
Totale 34.946
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Città #
Fairfield 2.572
Ashburn 2.019
Woodbridge 1.716
Chandler 1.283
Singapore 1.246
Houston 1.175
San Jose 1.118
Seattle 1.054
Jacksonville 980
Cambridge 883
Wilmington 783
Hong Kong 761
Nyköping 655
Milan 618
Ann Arbor 610
Council Bluffs 384
Beijing 364
Nanjing 355
Lawrence 287
Roxbury 283
New York 282
Lauterbourg 256
Rome 214
Boardman 211
Princeton 186
Los Angeles 179
Des Moines 175
Bari 171
Dallas 169
Helsinki 140
Ho Chi Minh City 133
Santa Clara 126
Brooklyn 125
São Paulo 125
San Diego 107
Washington 105
Nanchang 103
Dearborn 101
Inglewood 98
Buffalo 84
Shenyang 84
Jiaxing 75
Columbus 74
Hanoi 72
Hebei 72
Chicago 57
Rio de Janeiro 54
Tianjin 50
Brussels 47
London 47
Figino 46
Tokyo 42
Turin 42
Abidjan 41
Atlanta 41
San Francisco 41
Baghdad 39
Moscow 39
Naples 39
Dublin 38
Kunming 38
Munich 38
Changsha 36
Jinan 32
Toronto 31
Warsaw 30
Shanghai 29
Jakarta 28
Montreal 28
Pune 27
Guangzhou 26
Johannesburg 26
Paris 26
Phoenix 26
Tashkent 25
The Dalles 25
Curitiba 24
Medellín 24
Stockholm 24
Quito 23
Mexico City 22
San Mateo 22
Wuhan 22
Zhengzhou 22
Brasília 21
Managua 21
Orem 21
Belo Horizonte 20
Frankfurt am Main 20
Norwalk 20
San José 20
Bogotá 19
Bologna 19
Boston 19
Denver 19
Brno 18
Guatemala City 17
Mumbai 17
Riyadh 17
San Salvador 17
Totale 24.235
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Nome #
The First Example of a Dinuclear Platinum(III) Complex with Three Bridging Ligands 800
Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage 244
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 239
Mechanistic and structural basis for inhibition of copper trafficking by platinum anticancer drugs 237
Amyloid Transition of Ubiquitin on Silver Nanoparticles Produced by Pulsed Laser Ablation in Liquid as a Function of Stabilizer and Single-Point Mutations 220
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 210
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 206
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 203
Activation of platinum(IV) prodrugs by cytochrome c and characterization of the protein binding sites 195
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 190
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 187
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 186
Silver and gold nanoparticles produced by pulsed laser ablation in liquid to investigate their interaction with Ubiquitin 185
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 182
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 173
Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs 172
Effect of chirality in platinum drugs 170
Addition of Hydroxide, Alkoxide, and Carboxylate Anions to Platinum-bonded Ethylene 169
A General Procedure for the Selective Oxidation of Sulfides to Sulfoxides by Nitric Acid: Tetrabromoaurate(III) Catalyst in a Biphasic System 166
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 166
Isomerism of amides coordinated to platinum. X-ray crystal structure of dichloro-bisacetamide-platinum(II) 166
Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium 165
Processo di sintesi di complessi di platino con imminoeteri e loro utilizzazione come agenti antitumorali e agenti modificanti le basi nucleotidiche 163
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 163
Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity 163
Activation of Ketones by Electrophilic Metal Complexes. Synthesis of Some Ketonyl Platinum(II) Complexes and X-Ray Crystal Structure of [PtCl{CH2C(O)CH3}(1,10-phenanthroline)]·1/2Y (Y = H2O or CH2Cl2) 162
DNA fragment conformations in adducts with Kiteplatin 162
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 161
Insertion of terminal alkyne into Pt-N bond of the square planar [PtI2(Me2phen)] complex 161
Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione 161
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 159
A NMR, X-ray, and DFT combined study on the regio-chemistry of nucleophilic addition to platinum(II) coordinated terminal olefins 157
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 157
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 157
A Seven-Membered Platinum-Amino-Amidine Metallacycle. X-ray Structure of cis-[Pt(NH=CPhNButCH2CH2NHBut)Cl2].´Me2CO 156
Lantern-Shaped” Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt2{HN=C(But)O}4L2](NO3)2 156
Synthesis and X-ray Structural Characterization of Two Unbridged Diplatinum(III) Compounds: cis- and trans-Bis[bis(1-imino-1-methoxyethane)trichloroplatinum(III)]. Transient Species in the Oxidation of Platinum(II) to Platinum(IV) 155
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 152
Reaction of Histone H1 with trans-Platinum Complexes and the Effect on DNA Platination 152
Chiral discrimination in the formation reaction and at equilibrium for N,N,N ',N '-tetramethyl-1,2-diaminocyclohexane-PtG(2) complexes 151
C hiral Discrimination in Platinum Anticancer Drugs 151
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 150
Cisplatin reacts with histone H1 and the adduct forms a ternary complex with DNA 150
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 150
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 150
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 149
Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II) 148
Atropisomerization of cis-Bis(5'GMP)-Platinum(II)-Diamine complexes with Non-C2-symmetrical asymmetric diamine ligands containing NH groups directed to one side of the coordination plane 147
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 147
An updated view of translocator protein (TSPO) 146
C60@Lysozyme: Direct Observation by Nuclear Magnetic Resonance of a 1:1 Fullerene Protein Adduct 145
Computational metallomics of the anticancer drug cisplatin 145
Cytotoxic trans-oriented iminoether platinum complexes – Kinetics of binding to DNA oligonucleotides determined by 15N NMR spectroscopy 143
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 143
NMR and X-ray Structural Characterization of a Cisplatin Analogue Able To Slow Down the Pt−N7 Rotation of a Coordinated Guanine Base by a Billion-Fold Times: 2,2'-Bipiperidine(dimethylmalonato)platinum(II) Complex 142
An Updated View of Cisplatin Transport 141
A novel head-to-head conformer of d(GpG) cross-linked by Pt: New light on the conformation of such cross-links formed by Pt anticancer drugs 141
Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1 141
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 139
Cytotoxic trans-oriented platinum complexes only form adducts with single-stranded oligodeoxynucleotides 139
Structural biology of cisplatin complexes with cellular targets: the adduct with human copper chaperone Atox1 in aqueous solution 139
Aiding Factors in the Formation of Azaplatinacyclobutane Rings – X-ray and Crystal Structure of [Pt{CH(Ph)CH2NEt2-κC,κN}(N,N,N′,N′-tetramethylethylenediamine)]+ and of Its Open-Chain Precursor 139
Probing Zn(II), Cd(II), AND Hg(II) binding to human ubiquitin by x-ray crystallography 138
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 138
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 137
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 137
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 136
A new polymorph of dichlorido(1,10-phenanthroline)platinum(II) 136
Single-Stranded Oligonucleotide Adducts Formed by Pt Complexes Favoring Left-Handed Base Canting: Steric Effect of Flanking Residues and Relevance to DNA Adducts Formed by Pt Anticancer Drugs 136
Potentiation of cytotoxic action of cis-[PtCl2(NH3)(1M7AI)] by UVA irradiation. Mechanistic insights 136
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 135
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine 135
Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B 135
NMR and X-ray characterization of a platinum(II) complex with (−)sparteine 134
Platinum(II) complexes with the diethyl(aminomethyl)phosphonate ligand (amp): characterization, properties and unusual solution behavior 134
Copper Homeostasis in Humans and Bacteria 134
Insertion of alkynes into Pt-X bonds of square planar [PtX2(N-N)] (X = Cl, Br, I) complexes 133
Endocyclic versus exocyclic N-coordination to platinum(II) of some nitro-9-[(2-dialkylaminoethyl)amino]acridines 133
The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex 133
H/D exchange at sp(3) carbons in the coordination sphere of platinum(II) 132
Five-coordinate alkene complexes of palladium(II) and platinum(II) 132
Insights into the Molecular Mechanisms of Protein Platination from a Case Study: The Reaction of Anticancer Platinum(II) Iminoethers with Horse Heart Cytochrome c 132
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 131
Interference between copper transport systems and platinum drugs 131
Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG Box Proteins and Nucleotide Excision Repair of these adducts 130
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 130
The unexpected reactivity of Zeise's anion in strong basic medium discloses new substitution patterns at the platinum centre 129
19 F NMR Allows the Investigation of the Fate of Platinum(IV) Prodrugs in Physiological Conditions 129
Synthesis and characterisation of the amidine complexes trans-[PtCl(NH3){HN=C(NH2)R}2]Cl (R = Me, Ph, CH2Ph) derived from addition of NH3 to the coordinated nitriles in trans-[PtCl2(NCR)2] 128
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 128
Antitumor trans Platinum Complexes can Form Cross-Links with Adjacent Purine Groups 128
Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent 127
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 127
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring 127
X-ray structure and circular dichroism of pure rotamers of Bis[Guanosine-5'-monophosphate(-1)](N,N,N',N'-tetramethylcyclohexyl-1,2-diamine)platinum(II) complexes that have R,R and S,S configurations at the asymmetric diamine 126
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 126
Antitumor activity of trans platinum complexes 126
Trans-Platinum Compounds in Cancer Therapy: A largely Unexplored Strategy for Identifying Novel Antitumor Platinum Drugs 125
Platination of the copper transporter ATP7A involved in anticancer drug resistance 125
Chirality-Controlling Chelate (CCC) Ligands in Analogs of Platinum Anticancer Agents. Influence of N9 Substituents of Guanine Derivatives (G) on the Distribution of Chiral Conformers of (CCC)PtG2 with CCC = N,N'-Dimethyl-2,3-diaminobutane 124
Totale 15.857
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Categoria #
all - tutte 142.895
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 142.895
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.639 0 0 0 0 94 157 94 113 203 156 359 463
2022/20233.338 568 310 207 326 440 400 22 406 502 19 82 56
2023/20241.087 95 173 46 91 104 295 28 64 16 21 5 149
2024/20253.983 175 67 379 132 104 298 339 301 175 196 552 1.265
2025/20269.107 1.151 406 512 972 863 487 967 225 1.454 690 222 1.158
2026/20272.882 252 550 654 1.245 181 0 0 0 0 0 0 0
Totale 35.432