IRIS
NATILE, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 19.328
AS - Asia 6.343
EU - Europa 5.650
SA - Sud America 1.681
Continente sconosciuto - Info sul continente non disponibili 443
AF - Africa 219
OC - Oceania 19
Totale 33.683
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Nazione #
US - Stati Uniti d'America 19.112
SG - Singapore 2.493
CN - Cina 1.776
IT - Italia 1.488
BR - Brasile 1.321
RU - Federazione Russa 1.216
SE - Svezia 818
HK - Hong Kong 770
UA - Ucraina 453
FI - Finlandia 394
DE - Germania 393
VN - Vietnam 357
FR - Francia 317
GB - Regno Unito 263
IN - India 190
BD - Bangladesh 152
AR - Argentina 107
CA - Canada 89
IQ - Iraq 86
CO - Colombia 71
ID - Indonesia 67
TR - Turchia 64
MX - Messico 62
EC - Ecuador 57
ZA - Sudafrica 55
SA - Arabia Saudita 53
VE - Venezuela 48
BE - Belgio 47
JP - Giappone 45
PK - Pakistan 45
IE - Irlanda 44
ES - Italia 42
CI - Costa d'Avorio 41
PL - Polonia 36
MA - Marocco 30
UZ - Uzbekistan 29
MY - Malesia 26
PH - Filippine 26
CL - Cile 25
NL - Olanda 25
AT - Austria 24
TN - Tunisia 22
KZ - Kazakistan 21
CZ - Repubblica Ceca 19
KE - Kenya 18
IR - Iran 17
AU - Australia 16
JO - Giordania 16
PY - Paraguay 16
AE - Emirati Arabi Uniti 14
BO - Bolivia 14
CR - Costa Rica 13
JM - Giamaica 13
AZ - Azerbaigian 11
DZ - Algeria 10
EG - Egitto 10
OM - Oman 10
PE - Perù 10
ET - Etiopia 9
IL - Israele 9
LT - Lituania 9
UY - Uruguay 9
NG - Nigeria 8
PT - Portogallo 8
HR - Croazia 7
HU - Ungheria 7
NP - Nepal 7
TH - Thailandia 7
AL - Albania 6
PA - Panama 6
PS - Palestinian Territory 6
SY - Repubblica araba siriana 6
BG - Bulgaria 5
BH - Bahrain 5
DO - Repubblica Dominicana 5
GT - Guatemala 5
LB - Libano 5
LK - Sri Lanka 5
NI - Nicaragua 5
RS - Serbia 5
SK - Slovacchia (Repubblica Slovacca) 5
GE - Georgia 4
GR - Grecia 4
KG - Kirghizistan 4
DM - Dominica 3
EU - Europa 3
HN - Honduras 3
KR - Corea 3
RO - Romania 3
SN - Senegal 3
CG - Congo 2
CH - Svizzera 2
KH - Cambogia 2
LY - Libia 2
MK - Macedonia 2
MM - Myanmar 2
MN - Mongolia 2
MU - Mauritius 2
PR - Porto Rico 2
QA - Qatar 2
Totale 33.206
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Città #
Fairfield 2.572
Woodbridge 1.716
Ashburn 1.690
Chandler 1.283
Singapore 1.245
Houston 1.174
Seattle 1.053
Jacksonville 979
San Jose 930
Cambridge 883
Wilmington 783
Hong Kong 761
Nyköping 655
Milan 614
Ann Arbor 610
Beijing 363
Nanjing 355
Council Bluffs 353
Lawrence 287
Roxbury 283
New York 263
Lauterbourg 256
Boardman 210
Rome 206
Princeton 186
Des Moines 175
Bari 163
Dallas 163
Los Angeles 155
Helsinki 140
Ho Chi Minh City 133
Brooklyn 123
San Diego 107
Santa Clara 106
São Paulo 105
Nanchang 103
Dearborn 101
Inglewood 98
Shenyang 84
Buffalo 82
Jiaxing 75
Columbus 74
Hanoi 72
Hebei 72
Chicago 55
Rio de Janeiro 53
Tianjin 50
Brussels 47
Figino 46
London 46
Tokyo 42
Abidjan 41
Baghdad 39
Moscow 39
San Francisco 39
Dublin 38
Kunming 38
Munich 38
Turin 37
Changsha 36
Jinan 32
Atlanta 31
Shanghai 29
Warsaw 29
Jakarta 28
Naples 28
Pune 27
Guangzhou 26
Johannesburg 26
Paris 26
Washington 26
Tashkent 25
Curitiba 24
Medellín 24
Phoenix 24
Stockholm 24
The Dalles 24
Quito 23
Mexico City 22
San Mateo 22
Wuhan 22
Zhengzhou 22
Montreal 21
Belo Horizonte 20
Brasília 20
Frankfurt am Main 20
Orem 20
Boston 19
Denver 19
Bogotá 18
Brno 18
Norwalk 18
Toronto 18
Bologna 17
Mumbai 17
Riyadh 17
Charlotte 16
Chennai 16
Dhaka 16
Falkenstein 16
Totale 23.415
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Nome #
The First Example of a Dinuclear Platinum(III) Complex with Three Bridging Ligands 792
Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage 237
Mechanistic and structural basis for inhibition of copper trafficking by platinum anticancer drugs 226
Anticancer kiteplatin pyrophosphate derivatives show unexpected target selectivity for DNA 222
Amyloid Transition of Ubiquitin on Silver Nanoparticles Produced by Pulsed Laser Ablation in Liquid as a Function of Stabilizer and Single-Point Mutations 213
A Pt(IV) prodrug of kiteplatin with the bone-targeting pyrophosphate ligand 202
Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands 194
A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO) 190
Activation of platinum(IV) prodrugs by cytochrome c and characterization of the protein binding sites 189
Addition versus substitution in the reaction of diiodo(2,9-dimethyl-1,10-phenanthroline)platinum(II) with aromatic bases. X-ray crystal structures of the substitution products with 2-amino-pyridine and 1-methyl-cytosine 185
A new case of polymorphism in platinum(II) complexes: [PtBr2(2,9-dimethyl-1,10-phenanthroline)]? 181
Silver and gold nanoparticles produced by pulsed laser ablation in liquid to investigate their interaction with Ubiquitin 178
Dual-acting antitumor Pt(iv) prodrugs of kiteplatin with dichloroacetate axial ligands 173
Encapsulation of lipophilic kiteplatin Pt(IV) prodrugs in PLGA-PEG micelles 171
Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs 167
Addition of Hydroxide, Alkoxide, and Carboxylate Anions to Platinum-bonded Ethylene 166
Effect of chirality in platinum drugs 166
Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs. 165
Isomerism of amides coordinated to platinum. X-ray crystal structure of dichloro-bisacetamide-platinum(II) 162
Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium 161
Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds 159
Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity 158
Antitumor trans-platinum DNA adducts: NMR and HPLC study of the interaction between a trans-Pt(iminoether) complex and the deoxy decamer d(CCTCGCTCTC).d(GAGAGCGAGG) 157
Activation of Ketones by Electrophilic Metal Complexes. Synthesis of Some Ketonyl Platinum(II) Complexes and X-Ray Crystal Structure of [PtCl{CH2C(O)CH3}(1,10-phenanthroline)]·1/2Y (Y = H2O or CH2Cl2) 157
Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir 157
Insertion of terminal alkyne into Pt-N bond of the square planar [PtI2(Me2phen)] complex 156
DNA fragment conformations in adducts with Kiteplatin 155
A new dinuclear platinum complex with a nitrogen-containing geminal bisphosphonate as potential anticancer compound specifically targeted to bone tissues 155
Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione 155
A NMR, X-ray, and DFT combined study on the regio-chemistry of nucleophilic addition to platinum(II) coordinated terminal olefins 154
A General Procedure for the Selective Oxidation of Sulfides to Sulfoxides by Nitric Acid: Tetrabromoaurate(III) Catalyst in a Biphasic System 152
Lantern-Shaped” Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt2{HN=C(But)O}4L2](NO3)2 151
Chiral discrimination in the formation reaction and at equilibrium for N,N,N ',N '-tetramethyl-1,2-diaminocyclohexane-PtG(2) complexes 147
C hiral Discrimination in Platinum Anticancer Drugs 147
A Seven-Membered Platinum-Amino-Amidine Metallacycle. X-ray Structure of cis-[Pt(NH=CPhNButCH2CH2NHBut)Cl2].´Me2CO 146
Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)] 146
Synthesis and X-ray Structural Characterization of Two Unbridged Diplatinum(III) Compounds: cis- and trans-Bis[bis(1-imino-1-methoxyethane)trichloroplatinum(III)]. Transient Species in the Oxidation of Platinum(II) to Platinum(IV) 146
Cisplatin reacts with histone H1 and the adduct forms a ternary complex with DNA 145
Reaction of Histone H1 with trans-Platinum Complexes and the Effect on DNA Platination 145
Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions 145
Biomimetic hydroxyapatite/drug nanocrystals as potential bone substitutes with anti-tumour drug delivery properties 144
Platinum(IV) complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs affording an oxaliplatin analogue that overcomes cancer resistance 144
Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II) 143
Atropisomerization of cis-Bis(5'GMP)-Platinum(II)-Diamine complexes with Non-C2-symmetrical asymmetric diamine ligands containing NH groups directed to one side of the coordination plane 143
Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position 142
Hydroxyapatite nanocrystals as a smart, pH sensitive, delivery system for kiteplatin 142
One-Pot Synthesis of New Organometallic Compounds with Platinum-Carbon Bond 141
Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy 140
Computational metallomics of the anticancer drug cisplatin 140
Cytotoxic trans-oriented iminoether platinum complexes – Kinetics of binding to DNA oligonucleotides determined by 15N NMR spectroscopy 139
Conformer distribution in (cis-1,4-DACH)bis(guanosine5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin 138
An Updated View of Cisplatin Transport 137
Cytotoxic trans-oriented platinum complexes only form adducts with single-stranded oligodeoxynucleotides 136
Structural biology of cisplatin complexes with cellular targets: the adduct with human copper chaperone Atox1 in aqueous solution 136
An updated view of translocator protein (TSPO) 136
Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor 135
NMR and X-ray Structural Characterization of a Cisplatin Analogue Able To Slow Down the Pt−N7 Rotation of a Coordinated Guanine Base by a Billion-Fold Times: 2,2'-Bipiperidine(dimethylmalonato)platinum(II) Complex 134
Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours 134
Aiding Factors in the Formation of Azaplatinacyclobutane Rings – X-ray and Crystal Structure of [Pt{CH(Ph)CH2NEt2-κC,κN}(N,N,N′,N′-tetramethylethylenediamine)]+ and of Its Open-Chain Precursor 134
A novel head-to-head conformer of d(GpG) cross-linked by Pt: New light on the conformation of such cross-links formed by Pt anticancer drugs 134
A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data 133
Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1 133
Reactivity of kiteplatin with S-donor biomolecules and nucleotides 132
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine 132
A new polymorph of dichlorido(1,10-phenanthroline)platinum(II) 132
Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance 131
C60@Lysozyme: Direct Observation by Nuclear Magnetic Resonance of a 1:1 Fullerene Protein Adduct 131
Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B 130
NMR and X-ray characterization of a platinum(II) complex with (−)sparteine 130
Platinum(II) complexes with the diethyl(aminomethyl)phosphonate ligand (amp): characterization, properties and unusual solution behavior 130
Synthesis and Characterization of Platinum(II) Complexes of Diethyl [(Methylsulfinyl)methyl]phosphonate: Potential Drugs against Bone Tumors 130
H/D exchange at sp(3) carbons in the coordination sphere of platinum(II) 129
Single-Stranded Oligonucleotide Adducts Formed by Pt Complexes Favoring Left-Handed Base Canting: Steric Effect of Flanking Residues and Relevance to DNA Adducts Formed by Pt Anticancer Drugs 129
Potentiation of cytotoxic action of cis-[PtCl2(NH3)(1M7AI)] by UVA irradiation. Mechanistic insights 129
Insights into the Molecular Mechanisms of Protein Platination from a Case Study: The Reaction of Anticancer Platinum(II) Iminoethers with Horse Heart Cytochrome c 128
Endocyclic versus exocyclic N-coordination to platinum(II) of some nitro-9-[(2-dialkylaminoethyl)amino]acridines 128
The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex 128
Five-coordinate alkene complexes of palladium(II) and platinum(II) 127
Insertion of alkynes into Pt-X bonds of square planar [PtX2(N-N)] (X = Cl, Br, I) complexes 127
Platinum Complexes with the Novel Ligand Diethyl [(Methylsulfinyl)- methyl]phosphonate (SMP): Solid-State Characterization of Potassium Trichloro(SMP)platinum(II) which, in Solution, Gives Dichloro(SMP)- platinum(II) and Potassium Chloride 127
The unexpected reactivity of Zeise's anion in strong basic medium discloses new substitution patterns at the platinum centre 126
Processo di sintesi di complessi di platino con imminoeteri e loro utilizzazione come agenti antitumorali e agenti modificanti le basi nucleotidiche 126
Copper Homeostasis in Humans and Bacteria 125
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand 125
Interference between copper transport systems and platinum drugs 125
Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG Box Proteins and Nucleotide Excision Repair of these adducts 123
Trans-Platinum Compounds in Cancer Therapy: A largely Unexplored Strategy for Identifying Novel Antitumor Platinum Drugs 123
X-ray structure and circular dichroism of pure rotamers of Bis[Guanosine-5'-monophosphate(-1)](N,N,N',N'-tetramethylcyclohexyl-1,2-diamine)platinum(II) complexes that have R,R and S,S configurations at the asymmetric diamine 123
Synthesis, characterization, and in vitro evaluation of a new TSPO-selective bifunctional chelate ligand 123
Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent 123
Role of metal ions and hydrogen bond acceptors in the tautomeric equilibrium of nitro-9[(alkylamino)amino]-acridine drugs 122
Contribution of H-Bonding to the Preference of Platinum Anti-Tumour Drugs for Particular Bases and Particular Cross-Links 121
19 F NMR Allows the Investigation of the Fate of Platinum(IV) Prodrugs in Physiological Conditions 121
Platinum amides from platinum nitriles: X-ray crystal structure of trans-dichloro-bis(1-imino-1-hydroxy-2,2-dimethylpropane)platinum(II) 120
Antitumor trans Platinum Complexes can Form Cross-Links with Adjacent Purine Groups 120
Chirality-Controlling Chelate (CCC) Ligands in Analogs of Platinum Anticancer Agents. Influence of N9 Substituents of Guanine Derivatives (G) on the Distribution of Chiral Conformers of (CCC)PtG2 with CCC = N,N'-Dimethyl-2,3-diaminobutane 120
Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO) 119
Platination of the copper transporter ATP7A involved in anticancer drug resistance 119
Monitoring Interactions inside Cells by Advanced Spectroscopies: Overview of Copper Transporters and Cisplatin 119
A minimal structural variation can overcome tumour resistance of oxaliplatin: the case of 4,5-dehydrogenation of the cyclohexane ring 119
Totale 15.183
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Categoria #
all - tutte 135.355
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 135.355
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.732 0 0 21 72 94 157 94 113 203 156 359 463
2022/20233.338 568 310 207 326 440 400 22 406 502 19 82 56
2023/20241.087 95 173 46 91 104 295 28 64 16 21 5 149
2024/20253.983 175 67 379 132 104 298 339 301 175 196 552 1.265
2025/20269.107 1.151 406 512 972 863 487 967 225 1.454 690 222 1.158
2026/20271.133 252 550 331 0 0 0 0 0 0 0 0 0
Totale 33.683