IRIS
COTECCHIA, Susanna
 Distribuzione geografica
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Continente #
NA - Nord America 6.269
AS - Asia 2.228
EU - Europa 1.842
SA - Sud America 578
AF - Africa 60
Continente sconosciuto - Info sul continente non disponibili 58
OC - Oceania 6
Totale 11.041
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Nazione #
US - Stati Uniti d'America 6.190
SG - Singapore 989
IT - Italia 555
CN - Cina 528
BR - Brasile 459
HK - Hong Kong 311
UA - Ucraina 213
DE - Germania 210
RU - Federazione Russa 190
SE - Svezia 181
FI - Finlandia 168
FR - Francia 147
GB - Regno Unito 86
VN - Vietnam 85
IN - India 58
BD - Bangladesh 52
IQ - Iraq 43
AR - Argentina 42
CA - Canada 34
MX - Messico 19
TR - Turchia 19
CO - Colombia 18
PK - Pakistan 18
BE - Belgio 17
ID - Indonesia 17
VE - Venezuela 16
ZA - Sudafrica 16
ES - Italia 14
JP - Giappone 13
EC - Ecuador 11
PH - Filippine 11
IE - Irlanda 10
JO - Giordania 10
PL - Polonia 10
SA - Arabia Saudita 10
AZ - Azerbaigian 8
MA - Marocco 8
PY - Paraguay 8
BO - Bolivia 7
CL - Cile 7
ET - Etiopia 7
NL - Olanda 7
AT - Austria 6
DZ - Algeria 6
KE - Kenya 6
MY - Malesia 6
PE - Perù 6
UZ - Uzbekistan 6
AU - Australia 5
IL - Israele 5
LB - Libano 5
LT - Lituania 5
NI - Nicaragua 5
PS - Palestinian Territory 5
TH - Thailandia 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CH - Svizzera 4
HN - Honduras 4
KZ - Kazakistan 4
PA - Panama 4
AL - Albania 3
CR - Costa Rica 3
CZ - Repubblica Ceca 3
NP - Nepal 3
OM - Oman 3
AM - Armenia 2
CM - Camerun 2
DO - Repubblica Dominicana 2
EG - Egitto 2
HR - Croazia 2
JM - Giamaica 2
KG - Kirghizistan 2
KR - Corea 2
PT - Portogallo 2
RE - Reunion 2
RO - Romania 2
RS - Serbia 2
SN - Senegal 2
SR - Suriname 2
SV - El Salvador 2
UY - Uruguay 2
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
FJ - Figi 1
GA - Gabon 1
GP - Guadalupe 1
GT - Guatemala 1
HU - Ungheria 1
IR - Iran 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MD - Moldavia 1
PR - Porto Rico 1
QA - Qatar 1
SI - Slovenia 1
SY - Repubblica araba siriana 1
TG - Togo 1
TT - Trinidad e Tobago 1
Totale 10.983
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Città #
Woodbridge 721
Jacksonville 474
Chandler 468
Singapore 454
Fairfield 434
Houston 419
San Jose 375
Ashburn 348
Ann Arbor 341
Hong Kong 308
Milan 282
Seattle 157
Cambridge 154
Council Bluffs 148
Wilmington 147
Lawrence 123
Roxbury 120
Nyköping 108
Lauterbourg 105
Beijing 104
Nanjing 104
Boardman 86
Rome 67
Des Moines 66
Los Angeles 66
Columbus 63
Inglewood 59
Dallas 53
New York 51
Helsinki 47
Buffalo 44
Santa Clara 43
São Paulo 42
Shenyang 34
Hebei 33
Nanchang 31
Ho Chi Minh City 30
Somma Vesuviana 30
Grafing 29
Bari 28
Brooklyn 26
San Diego 25
Dearborn 24
Jiaxing 23
Marseille 22
Figino 21
Falkenstein 19
Hanoi 18
Baghdad 17
Changsha 17
Brussels 16
Chicago 15
Rio de Janeiro 15
Paris 14
Tianjin 14
Auburn Hills 13
London 13
Tokyo 13
Princeton 12
San Francisco 12
Turin 12
Dhaka 11
Romola 11
Amman 10
Guangzhou 10
Stockholm 10
Dublin 9
Hefei 9
Munich 9
Phoenix 9
Belo Horizonte 8
Brasília 8
Jinan 8
Kunming 8
Maceió 8
Warsaw 8
Atlanta 7
Baku 7
Guarulhos 7
Johannesburg 7
Lahore 7
Manchester 7
Norwalk 7
Nuremberg 7
Pune 7
Addis Ababa 6
Bogotá 6
Campinas 6
Charlotte 6
Curitiba 6
Denver 6
Miami 6
Palermo 6
The Bronx 6
Toronto 6
Biên Hòa 5
Buenos Aires 5
Chennai 5
Lima 5
Managua 5
Totale 7.441
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Nome #
The alpha1-adrenergic receptors in cardiac hypertrophy: Signaling mechanisms and functional implications 179
A behavioral study of the alpha1b-adrenergic receptor knock out mice : increased reaction to novelty and selectively reduced learning capacities 165
AKAP-Lbc mediates protection against doxorubicin-induced cardiomyocyte toxicity 165
The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation 155
Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors 151
Gain-of-function mutations of the V2 vasopressin receptor in nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a cell-based assay to assess constitutive water reabsorption 136
Enhanced vascular contractility in alpha1-adrenergic receptor-deficient mice 135
A mutation-induced activated state of the beta2-adrenergic receptor. Extending the ternary complex model 134
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex 132
Alpha1-adrenoceptors are required for normal male sexual function 130
Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization 128
B2 kinin receptor-mediated internalization of bradykinin in DDT1 MF-2 smooth muscle cells is paralleled by sequestration of the occupied receptors 125
Alpha1-adrenoceptor-dependent vascular hypertrophy and remodeling in murine hypoxic pulmonary hypertension 122
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)- RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states 120
Altered cathecolamine receptor affinity in rabbit aortic intimal hyperplasia 119
Agonist-dependent phosphorylation of the alpha2-adrenergic receptor by the beta-adrenergic receptor kinase 119
Constitutive activity and inverse agonism at the alpha1adrenoceptors 117
Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor 117
Protein-Protein Interactions at the Adrenergic Receptors. 114
Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice 114
Signal transduction mechanisms of the calcium sensing receptor in neonatal rat cardiac fibroblasts and myocytes: A re-evaluation with real-time imaging and electrophysiological approaches 114
Constitutively active mutants of the alpha2-adrenergic receptor 113
Theoretical study on the electrostatically driven step of receptor-G protein recognition 113
null 113
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice 111
d-amphetamine induced anorexia and motor behaviour after chronic treatment in rats : relationship with changes in the number of catecholamine receptor sites in the brain 109
D-Amphetamine fails to increase extracellular dopamine levels in mice lacking alpha1b-adrenergic receptors: relationship between functional and nonfunctional dopamine release 109
Ab initio modeling of the alpha1b-adrenergic receptor activation 109
Molecular cloning and expression of the cDNA for the hamster alpha1-adrenergic receptor 108
Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: further differences in docking catecholamines to receptor subtypes 107
Agonist-induced beta-adrenoceptor internalization on intact human mononuclear leukocytes : effect of temperature of mononuclear leukocyte separation 106
Alpha1A/C- and alpha1B adrenergic receptors are required for physiological cardiac hypertrophy in the double knockout mice 105
Phorbol esters promote alpha1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism 103
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins 103
Constitutively active G protein-coupled receptor mutants: implications on receptor function and drug action 100
Selective changes of receptor binding in brain regions of aged rats 100
Stress induced desensitization of lymphocyte beta-adrenoceptors in young and aged rats 99
A-Kinase-Anchoring Protein-Lbc Anchors IκB Kinase β To Support Interleukin-6-Mediated Cardiomyocyte Hypertrophy. 99
Does ethyl-beta-carboline-3-carboxylate interact with mouse brain benzodiazepine receptors in vivo ? 98
Inverse agonism and neutral antagonism at the alpha1a and alpha1b-adrenergic receptor subtypes 98
The alpha1-adrenergic receptors: diversity of signaling networks and regulation 97
Adrenergic, dopaminergic and muscarinic receptor stimulation leads to protein kinase A phosphorylation of the Na,K-ATPase 97
Constitutively active mutants of the alpha1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation 97
Chromosomal organization of adrenergic receptor genes 97
A constitutively active mutant of the alpha1B-adrenergic receptor can cause greater agonist-induced down-regulation of the G-proteins Gqalpha and G11alpha than the wild type 96
Benzodiazepines: relationship between pharmacological activity in the rat and in vivo receptor binding 96
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates 95
Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein 92
Phorbol esters effect on alpha1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells 92
Comparison of [3H]tamsulosin and [3H]prazosin binding to wild-type and constitutively active alpha1b-adrenoceptors 92
Molecular mechanisms underlying the activation and regulation of the alpha1B-adrenergic receptor 90
Livelli sierici di farmaci anticonvulsivanti in pazienti con epilessia non controllata: risultati preliminari 90
Co- and Post-translational modifications of the alpha1b-adrenergic receptor: effects on receptor expression and function 90
Effector coupling mechanisms of the cloned 5-HT1A receptor 88
Constitutively active alpha1b-adrenergic receptor mutants display different phosphorylation and internalization properties 88
A quantitative analysis of antagonism and inverse agonism at the wild-type and constitutively active hamster apha1B-adrenoceptors 88
Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes 88
Molecular cloning and expression of the cDNA for the alpha1A-adrenergic receptor 87
Norepinephrine decreases EGF binding in primary rat hepatocytes cultures 87
Neuroendocrine deregulation of food intake, adipose tissue and the gastrointestinal system in obesity and metabolic syndrome 87
G protein-coupled receptors as proto-oncogenes : Constitutively activating mutation of the alpha1B-adrenergic receptor enhances mitogenesis and tumorigenicity 86
Costimulation of adenylyl cyclase and phopsholipase C by a mutant alpha1B-adrenergic receptor transgene promotes malignant transformation of thyroid cells 85
Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies 85
Discrete amino acid sequences of the alpha1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis 84
Correlation between vasoconstrictor roles and mRNA expression of alpha(1)-adrenoceptor subtypes in blood vessels of genetically engineered mice 84
Constitutively active G protein-coupled receptors : potential mechanisms of receptor activation 83
Constitutive activation of an adrenergic receptor by all amino acid substitutions at a single site 83
Expression and secretion of the atrial natriuretic peptide in human adipose tissue and preadipocytes 83
Oligomerization of the alpha1a- and alpha1b-adrenergic receptor subytpes: potential implications in receptor internalization 80
Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta2-adrenergic receptor 78
Molecular biology of the adrenergic receptors 78
Role of brain alpha1B-adrenergic receptors in modafinil-induced behavioral activity 77
Drugs : Guide and caveats to explanatory and descriptive approaches 77
Direct interaction of ezrin with the alpha1b-adrenergic receptor regulates recycling of the internalized receptors 77
Constitutively activating mutations of the beta1-adrenergic receptor 77
Expression of the alpha1b-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest Virus expression system 77
Glucocorticoids increase the number of lymphocytes beta-adrenoceptors in vitro 76
Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor 76
The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of an highly conserved aspartate 75
Expression of the adrenergic receptor subtypes in adipose tissue of morbid obese humans. 75
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy 75
Constitutive activity and inverse agonism at the alpha1a and alpha1b-adrenergic receptor subtypes 74
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells 74
Molecular mechanisms involved in the activation and regulation of the alpha1-adrenergic receptor subtypes 74
null 74
Adrenergic receptors: recent insights into their mechanisms of activation and desensitization 74
Sulphinpirazone increases lymphocyte beta-adrenoceptors in man 73
Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction 73
Ezrin directly interacts with AQP2 and promotes its endocytosis 73
Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation 73
Coupling of the expressed alpha1B-adrenergic receptor to the phopholipase C pathway in Xenopus oocytes. The role of Go 72
Blockade of both alpha1A- and alpha1B-adrenergic receptor subtype signaling is required to inhibit neointimal formation in the mouse femoral artery 71
Mutagenesis and modelling of the alpha1b-adrenergic receptor highlights the role of the helix3/helix 6 interface in receptor activation 70
Changes in serotonin, but not catecholamine receptor binding in the brain of morphine-dependent rats 70
Brain levels of tofisopam in the rat and relationship with benzodiazepine receptors 70
Gene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodeling 68
HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants 67
Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonists 67
Molecular cloning and expression of the cDNA for a novel alpha1-adrenergic receptor subtype 66
Mutational analysis of the highly conserved arginine within the E/DRY motif of the alpha1b-adrenergic receptor: effects on receptor isomerization and activation 65
Totale 9.647
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Categoria #
all - tutte 45.013
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.013
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022591 0 0 0 93 20 35 15 63 48 38 132 147
2022/20231.139 158 70 32 160 163 157 15 96 244 7 21 16
2023/2024358 42 81 10 110 33 39 3 7 0 4 7 22
2024/20251.486 9 15 168 55 13 151 137 87 58 78 192 523
2025/20263.060 448 119 207 274 339 158 327 88 243 286 93 478
2026/2027527 116 181 230 0 0 0 0 0 0 0 0 0
Totale 11.041