IRIS
COTECCHIA, Susanna
 Distribuzione geografica
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Continente #
NA - Nord America 4.740
EU - Europa 889
AS - Asia 540
OC - Oceania 4
SA - Sud America 3
Totale 6.176
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Nazione #
US - Stati Uniti d'America 4.733
CN - Cina 383
UA - Ucraina 207
DE - Germania 174
SE - Svezia 171
SG - Singapore 148
FI - Finlandia 119
IT - Italia 93
GB - Regno Unito 52
FR - Francia 36
BE - Belgio 17
IE - Irlanda 8
CA - Canada 6
IN - India 5
AU - Australia 4
CZ - Repubblica Ceca 3
NL - Olanda 3
RU - Federazione Russa 3
BR - Brasile 2
CH - Svizzera 2
HK - Hong Kong 2
CO - Colombia 1
ES - Italia 1
KR - Corea 1
MX - Messico 1
VN - Vietnam 1
Totale 6.176
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Città #
Woodbridge 721
Jacksonville 474
Chandler 468
Fairfield 434
Houston 411
Ann Arbor 341
Ashburn 163
Cambridge 154
Seattle 151
Wilmington 147
Lawrence 123
Roxbury 120
Singapore 116
Nyköping 108
Nanjing 104
Boardman 82
Des Moines 64
Beijing 61
Inglewood 59
Shenyang 34
Hebei 33
Nanchang 31
Somma Vesuviana 30
Grafing 29
New York 27
San Diego 25
Dearborn 24
Santa Clara 24
Bari 23
Jiaxing 23
Marseille 22
Los Angeles 19
Brooklyn 17
Changsha 17
Brussels 16
Tianjin 14
Auburn Hills 13
Paris 12
Princeton 12
Romola 11
Guangzhou 9
Hefei 8
Jinan 8
Kunming 8
Dublin 7
Norwalk 7
London 6
Pune 5
Wuhan 5
Zhengzhou 5
Munich 4
Redmond 4
Toronto 4
Washington 4
Castenedolo 3
Detroit 3
Redwood City 3
Brisbane 2
Brno 2
Catania 2
Helsinki 2
Herndon 2
Islington 2
Kirkland 2
Palermo 2
Prescot 2
Acton 1
Altay 1
Augusta 1
Baotou 1
Braintree 1
Brownsville 1
Brussel 1
Carmiano 1
Carol Stream 1
Central 1
Chengdu 1
Chicago 1
Chiswick 1
Chongqing 1
Clifton 1
Curitiba 1
Dallas 1
Esslingen am Neckar 1
Folkestone 1
Forest City 1
Frankfurt am Main 1
Gioia Del Colle 1
Groningen 1
Hanoi 1
Hong Kong 1
Juarez 1
Lancaster 1
Leawood 1
Lianyun 1
Madrid 1
Medellín 1
Miami 1
Montreal 1
Ningbo 1
Totale 4.902
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Nome #
The alpha1-adrenergic receptors in cardiac hypertrophy: Signaling mechanisms and functional implications 134
A behavioral study of the alpha1b-adrenergic receptor knock out mice : increased reaction to novelty and selectively reduced learning capacities 113
null 113
Gain-of-function mutations of the V2 vasopressin receptor in nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a cell-based assay to assess constitutive water reabsorption 102
AKAP-Lbc mediates protection against doxorubicin-induced cardiomyocyte toxicity 99
Enhanced vascular contractility in alpha1-adrenergic receptor-deficient mice 93
Protein-Protein Interactions at the Adrenergic Receptors. 89
Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors 88
B2 kinin receptor-mediated internalization of bradykinin in DDT1 MF-2 smooth muscle cells is paralleled by sequestration of the occupied receptors 87
Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor 80
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex 80
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)- RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states 79
Phorbol esters promote alpha1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism 78
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice 78
Theoretical study on the electrostatically driven step of receptor-G protein recognition 78
Molecular cloning and expression of the cDNA for the hamster alpha1-adrenergic receptor 78
Constitutively active mutants of the alpha2-adrenergic receptor 77
null 74
A mutation-induced activated state of the beta2-adrenergic receptor. Extending the ternary complex model 73
Alpha1-adrenoceptor-dependent vascular hypertrophy and remodeling in murine hypoxic pulmonary hypertension 72
Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization 72
Selective changes of receptor binding in brain regions of aged rats 71
Constitutive activity and inverse agonism at the alpha1adrenoceptors 69
Constitutively active mutants of the alpha1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation 68
Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes 68
D-Amphetamine fails to increase extracellular dopamine levels in mice lacking alpha1b-adrenergic receptors: relationship between functional and nonfunctional dopamine release 67
Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice 66
Constitutively active G protein-coupled receptor mutants: implications on receptor function and drug action 65
d-amphetamine induced anorexia and motor behaviour after chronic treatment in rats : relationship with changes in the number of catecholamine receptor sites in the brain 64
Chromosomal organization of adrenergic receptor genes 64
Stress induced desensitization of lymphocyte beta-adrenoceptors in young and aged rats 62
Alpha1-adrenoceptors are required for normal male sexual function 62
Agonist-dependent phosphorylation of the alpha2-adrenergic receptor by the beta-adrenergic receptor kinase 62
Benzodiazepines: relationship between pharmacological activity in the rat and in vivo receptor binding 60
Molecular mechanisms underlying the activation and regulation of the alpha1B-adrenergic receptor 59
Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: further differences in docking catecholamines to receptor subtypes 59
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins 59
Altered cathecolamine receptor affinity in rabbit aortic intimal hyperplasia 58
Ab initio modeling of the alpha1b-adrenergic receptor activation 58
Does ethyl-beta-carboline-3-carboxylate interact with mouse brain benzodiazepine receptors in vivo ? 57
Agonist-induced beta-adrenoceptor internalization on intact human mononuclear leukocytes : effect of temperature of mononuclear leukocyte separation 57
Adrenergic, dopaminergic and muscarinic receptor stimulation leads to protein kinase A phosphorylation of the Na,K-ATPase 57
Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies 57
Neuroendocrine deregulation of food intake, adipose tissue and the gastrointestinal system in obesity and metabolic syndrome 57
Effector coupling mechanisms of the cloned 5-HT1A receptor 56
Inverse agonism and neutral antagonism at the alpha1a and alpha1b-adrenergic receptor subtypes 56
Comparison of [3H]tamsulosin and [3H]prazosin binding to wild-type and constitutively active alpha1b-adrenoceptors 54
The alpha1-adrenergic receptors: diversity of signaling networks and regulation 53
Alpha1A/C- and alpha1B adrenergic receptors are required for physiological cardiac hypertrophy in the double knockout mice 52
Constitutively active alpha1b-adrenergic receptor mutants display different phosphorylation and internalization properties 51
Molecular biology of the adrenergic receptors 51
Constitutive activation of an adrenergic receptor by all amino acid substitutions at a single site 50
Constitutive activity and inverse agonism at the alpha1a and alpha1b-adrenergic receptor subtypes 50
Molecular cloning and expression of the cDNA for the alpha1A-adrenergic receptor 50
Role of brain alpha1B-adrenergic receptors in modafinil-induced behavioral activity 49
A constitutively active mutant of the alpha1B-adrenergic receptor can cause greater agonist-induced down-regulation of the G-proteins Gqalpha and G11alpha than the wild type 49
G protein-coupled receptors as proto-oncogenes : Constitutively activating mutation of the alpha1B-adrenergic receptor enhances mitogenesis and tumorigenicity 49
Phorbol esters effect on alpha1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells 48
Drugs : Guide and caveats to explanatory and descriptive approaches 48
Discrete amino acid sequences of the alpha1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis 48
Oligomerization of the alpha1a- and alpha1b-adrenergic receptor subytpes: potential implications in receptor internalization 48
Co- and Post-translational modifications of the alpha1b-adrenergic receptor: effects on receptor expression and function 48
The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation 48
Costimulation of adenylyl cyclase and phopsholipase C by a mutant alpha1B-adrenergic receptor transgene promotes malignant transformation of thyroid cells 47
Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein 46
Norepinephrine decreases EGF binding in primary rat hepatocytes cultures 46
Coupling of the expressed alpha1B-adrenergic receptor to the phopholipase C pathway in Xenopus oocytes. The role of Go 46
Glucocorticoids increase the number of lymphocytes beta-adrenoceptors in vitro 44
Correlation between vasoconstrictor roles and mRNA expression of alpha(1)-adrenoceptor subtypes in blood vessels of genetically engineered mice 44
Constitutively active G protein-coupled receptors : potential mechanisms of receptor activation 43
A-Kinase-Anchoring Protein-Lbc Anchors IκB Kinase β To Support Interleukin-6-Mediated Cardiomyocyte Hypertrophy. 43
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates 43
Direct interaction of ezrin with the alpha1b-adrenergic receptor regulates recycling of the internalized receptors 42
Expression of the alpha1b-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest Virus expression system 42
The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of an highly conserved aspartate 41
Expression of the adrenergic receptor subtypes in adipose tissue of morbid obese humans. 41
Livelli sierici di farmaci anticonvulsivanti in pazienti con epilessia non controllata: risultati preliminari 41
Sulphinpirazone increases lymphocyte beta-adrenoceptors in man 41
Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta2-adrenergic receptor 40
Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor 40
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells 39
Changes in serotonin, but not catecholamine receptor binding in the brain of morphine-dependent rats 38
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy 38
A quantitative analysis of antagonism and inverse agonism at the wild-type and constitutively active hamster apha1B-adrenoceptors 37
Ezrin directly interacts with AQP2 and promotes its endocytosis 37
Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation 36
The alpha1C-adrenergic receptor: a new member in the alpha1-adrenergic receptor family 35
Constitutively activating mutations of the beta1-adrenergic receptor 34
Decreased blood pressure response in mice deficient of the alpha1B-adrenergic receptor 34
Mammalian alpha1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit 34
Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships 34
Adrenergic receptors: recent insights into their mechanisms of activation and desensitization 34
Gene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodeling 33
HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants 33
Mutagenesis and modelling of the alpha1b-adrenergic receptor highlights the role of the helix3/helix 6 interface in receptor activation 33
The adaptor complex 2 directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor endocyosis 33
Catechol-binding serines of the beta2-adrenergic receptors control the equilibrium between the active and inactive receptor states 33
Signal transduction mechanisms of the calcium sensing receptor in neonatal rat cardiac fibroblasts and myocytes: A re-evaluation with real-time imaging and electrophysiological approaches 33
Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells 32
Regulatory mechanisms of alpha1b-adrenergic receptor function 31
Totale 5.642
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Categoria #
all - tutte 25.478
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.478
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020786 0 0 0 0 127 67 147 82 140 35 167 21
2020/2021853 97 26 93 14 91 32 154 27 122 124 40 33
2021/2022708 24 93 0 93 20 35 15 63 48 38 132 147
2022/20231.139 158 70 32 160 163 157 15 96 244 7 21 16
2023/2024358 42 81 10 110 33 39 3 7 0 4 7 22
2024/2025260 9 15 168 55 13 0 0 0 0 0 0 0
Totale 6.228