IRIS
COTECCHIA, Susanna
 Distribuzione geografica
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Continente #
NA - Nord America 4.762
EU - Europa 1.091
AS - Asia 695
SA - Sud America 123
AF - Africa 4
OC - Oceania 4
Totale 6.679
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Nazione #
US - Stati Uniti d'America 4.751
CN - Cina 383
SG - Singapore 275
UA - Ucraina 208
DE - Germania 180
RU - Federazione Russa 175
SE - Svezia 171
FI - Finlandia 121
BR - Brasile 114
IT - Italia 106
GB - Regno Unito 52
FR - Francia 37
BE - Belgio 17
HK - Hong Kong 10
IE - Irlanda 8
CA - Canada 6
IN - India 5
NL - Olanda 5
AU - Australia 4
ID - Indonesia 4
CZ - Repubblica Ceca 3
IQ - Iraq 3
TR - Turchia 3
AR - Argentina 2
AT - Austria 2
AZ - Azerbaigian 2
CH - Svizzera 2
KE - Kenya 2
KR - Corea 2
MX - Messico 2
PE - Perù 2
VE - Venezuela 2
AM - Armenia 1
BD - Bangladesh 1
BY - Bielorussia 1
CO - Colombia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EC - Ecuador 1
ES - Italia 1
JM - Giamaica 1
JO - Giordania 1
KG - Kirghizistan 1
LV - Lettonia 1
PS - Palestinian Territory 1
PT - Portogallo 1
SV - El Salvador 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
UZ - Uzbekistan 1
VN - Vietnam 1
Totale 6.679
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Città #
Woodbridge 721
Jacksonville 474
Chandler 468
Fairfield 434
Houston 411
Ann Arbor 341
Ashburn 164
Cambridge 154
Seattle 151
Wilmington 147
Singapore 140
Lawrence 123
Roxbury 120
Nyköping 108
Nanjing 104
Boardman 82
Des Moines 64
Beijing 61
Inglewood 59
Shenyang 34
Hebei 33
Nanchang 31
Somma Vesuviana 30
Grafing 29
New York 27
Bari 26
San Diego 25
Dearborn 24
Santa Clara 24
Jiaxing 23
Los Angeles 23
Marseille 22
Brooklyn 17
Changsha 17
Brussels 16
Tianjin 14
Auburn Hills 13
Paris 12
Princeton 12
São Paulo 12
Romola 11
Guangzhou 9
Hong Kong 9
Hefei 8
Jinan 8
Kunming 8
Dublin 7
Norwalk 7
London 6
Rio de Janeiro 6
Pune 5
Wuhan 5
Zhengzhou 5
Helsinki 4
Munich 4
Nuremberg 4
Redmond 4
Toronto 4
Washington 4
Campinas 3
Castenedolo 3
Catania 3
Council Bluffs 3
Detroit 3
Redwood City 3
Baku 2
Belo Horizonte 2
Brasília 2
Brisbane 2
Brno 2
Campo Grande 2
Caçapava 2
Contagem 2
Fortaleza 2
Herndon 2
Imperatriz 2
Islington 2
Jakarta 2
Kirkland 2
Lima 2
Maricá 2
Nairobi 2
Noci 2
Palermo 2
Porto Alegre 2
Prescot 2
São José do Rio Preto 2
Vienna 2
Acton 1
Algiers 1
Altay 1
Amman 1
Andradina 1
Anápolis 1
Apucarana 1
Aracaju 1
Araxá 1
Arraial do Cabo 1
Augusta 1
Bahía Blanca 1
Totale 4.984
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Nome #
The alpha1-adrenergic receptors in cardiac hypertrophy: Signaling mechanisms and functional implications 137
A behavioral study of the alpha1b-adrenergic receptor knock out mice : increased reaction to novelty and selectively reduced learning capacities 119
null 113
AKAP-Lbc mediates protection against doxorubicin-induced cardiomyocyte toxicity 109
Gain-of-function mutations of the V2 vasopressin receptor in nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a cell-based assay to assess constitutive water reabsorption 106
Enhanced vascular contractility in alpha1-adrenergic receptor-deficient mice 98
Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors 94
Protein-Protein Interactions at the Adrenergic Receptors. 91
B2 kinin receptor-mediated internalization of bradykinin in DDT1 MF-2 smooth muscle cells is paralleled by sequestration of the occupied receptors 89
Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex 85
Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor 83
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice 83
Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)- RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states 82
Molecular cloning and expression of the cDNA for the hamster alpha1-adrenergic receptor 82
Alpha1-adrenoceptor-dependent vascular hypertrophy and remodeling in murine hypoxic pulmonary hypertension 81
Theoretical study on the electrostatically driven step of receptor-G protein recognition 81
Phorbol esters promote alpha1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism 80
A mutation-induced activated state of the beta2-adrenergic receptor. Extending the ternary complex model 80
D-Amphetamine fails to increase extracellular dopamine levels in mice lacking alpha1b-adrenergic receptors: relationship between functional and nonfunctional dopamine release 79
Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization 79
Constitutively active mutants of the alpha2-adrenergic receptor 78
Constitutive activity and inverse agonism at the alpha1adrenoceptors 77
null 74
Selective changes of receptor binding in brain regions of aged rats 73
Alpha1-adrenoceptors are required for normal male sexual function 71
Constitutively active mutants of the alpha1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation 70
Agonist-dependent phosphorylation of the alpha2-adrenergic receptor by the beta-adrenergic receptor kinase 70
Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes 69
d-amphetamine induced anorexia and motor behaviour after chronic treatment in rats : relationship with changes in the number of catecholamine receptor sites in the brain 68
Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: further differences in docking catecholamines to receptor subtypes 68
Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice 68
Chromosomal organization of adrenergic receptor genes 67
Constitutively active G protein-coupled receptor mutants: implications on receptor function and drug action 66
Altered cathecolamine receptor affinity in rabbit aortic intimal hyperplasia 66
Ab initio modeling of the alpha1b-adrenergic receptor activation 65
Stress induced desensitization of lymphocyte beta-adrenoceptors in young and aged rats 64
Agonist-induced beta-adrenoceptor internalization on intact human mononuclear leukocytes : effect of temperature of mononuclear leukocyte separation 64
The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation 64
Adrenergic, dopaminergic and muscarinic receptor stimulation leads to protein kinase A phosphorylation of the Na,K-ATPase 63
Benzodiazepines: relationship between pharmacological activity in the rat and in vivo receptor binding 63
Does ethyl-beta-carboline-3-carboxylate interact with mouse brain benzodiazepine receptors in vivo ? 62
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins 62
Neuroendocrine deregulation of food intake, adipose tissue and the gastrointestinal system in obesity and metabolic syndrome 61
Molecular mechanisms underlying the activation and regulation of the alpha1B-adrenergic receptor 60
Comparison of [3H]tamsulosin and [3H]prazosin binding to wild-type and constitutively active alpha1b-adrenoceptors 60
Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies 60
The alpha1-adrenergic receptors: diversity of signaling networks and regulation 59
Alpha1A/C- and alpha1B adrenergic receptors are required for physiological cardiac hypertrophy in the double knockout mice 59
Effector coupling mechanisms of the cloned 5-HT1A receptor 58
Inverse agonism and neutral antagonism at the alpha1a and alpha1b-adrenergic receptor subtypes 58
G protein-coupled receptors as proto-oncogenes : Constitutively activating mutation of the alpha1B-adrenergic receptor enhances mitogenesis and tumorigenicity 57
A constitutively active mutant of the alpha1B-adrenergic receptor can cause greater agonist-induced down-regulation of the G-proteins Gqalpha and G11alpha than the wild type 56
Discrete amino acid sequences of the alpha1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis 55
Molecular cloning and expression of the cDNA for the alpha1A-adrenergic receptor 54
A-Kinase-Anchoring Protein-Lbc Anchors IκB Kinase β To Support Interleukin-6-Mediated Cardiomyocyte Hypertrophy. 54
Molecular biology of the adrenergic receptors 54
Constitutive activation of an adrenergic receptor by all amino acid substitutions at a single site 53
Oligomerization of the alpha1a- and alpha1b-adrenergic receptor subytpes: potential implications in receptor internalization 52
Constitutive activity and inverse agonism at the alpha1a and alpha1b-adrenergic receptor subtypes 52
Constitutively active alpha1b-adrenergic receptor mutants display different phosphorylation and internalization properties 52
Role of brain alpha1B-adrenergic receptors in modafinil-induced behavioral activity 51
Phorbol esters effect on alpha1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells 51
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates 51
Drugs : Guide and caveats to explanatory and descriptive approaches 50
Coupling of the expressed alpha1B-adrenergic receptor to the phopholipase C pathway in Xenopus oocytes. The role of Go 50
Co- and Post-translational modifications of the alpha1b-adrenergic receptor: effects on receptor expression and function 50
Costimulation of adenylyl cyclase and phopsholipase C by a mutant alpha1B-adrenergic receptor transgene promotes malignant transformation of thyroid cells 49
Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein 48
Glucocorticoids increase the number of lymphocytes beta-adrenoceptors in vitro 48
Norepinephrine decreases EGF binding in primary rat hepatocytes cultures 48
Constitutively active G protein-coupled receptors : potential mechanisms of receptor activation 46
Correlation between vasoconstrictor roles and mRNA expression of alpha(1)-adrenoceptor subtypes in blood vessels of genetically engineered mice 46
Expression of the alpha1b-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest Virus expression system 46
Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta2-adrenergic receptor 45
A quantitative analysis of antagonism and inverse agonism at the wild-type and constitutively active hamster apha1B-adrenoceptors 45
Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor 44
Direct interaction of ezrin with the alpha1b-adrenergic receptor regulates recycling of the internalized receptors 44
Expression of the adrenergic receptor subtypes in adipose tissue of morbid obese humans. 44
The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of an highly conserved aspartate 43
Livelli sierici di farmaci anticonvulsivanti in pazienti con epilessia non controllata: risultati preliminari 43
Sulphinpirazone increases lymphocyte beta-adrenoceptors in man 43
Signal transduction mechanisms of the calcium sensing receptor in neonatal rat cardiac fibroblasts and myocytes: A re-evaluation with real-time imaging and electrophysiological approaches 43
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells 42
Changes in serotonin, but not catecholamine receptor binding in the brain of morphine-dependent rats 41
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy 41
Adrenergic receptors: recent insights into their mechanisms of activation and desensitization 40
Ezrin directly interacts with AQP2 and promotes its endocytosis 39
Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation 39
Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships 38
Catechol-binding serines of the beta2-adrenergic receptors control the equilibrium between the active and inactive receptor states 38
Constitutively activating mutations of the beta1-adrenergic receptor 37
Decreased blood pressure response in mice deficient of the alpha1B-adrenergic receptor 37
The alpha1C-adrenergic receptor: a new member in the alpha1-adrenergic receptor family 37
Mammalian alpha1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit 36
Truncation of the receptor impairs agonist-induced phosphorylation and desensitization of the alpha1B-adrenergic receptor 36
The adaptor complex 2 directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor endocyosis 36
Gene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodeling 34
HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants 34
Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells 34
Mutagenesis and modelling of the alpha1b-adrenergic receptor highlights the role of the helix3/helix 6 interface in receptor activation 33
Totale 6.057
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Categoria #
all - tutte 28.974
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.974
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020223 0 0 0 0 0 0 0 0 0 35 167 21
2020/2021853 97 26 93 14 91 32 154 27 122 124 40 33
2021/2022708 24 93 0 93 20 35 15 63 48 38 132 147
2022/20231.139 158 70 32 160 163 157 15 96 244 7 21 16
2023/2024358 42 81 10 110 33 39 3 7 0 4 7 22
2024/2025768 9 15 168 55 13 151 137 87 58 75 0 0
Totale 6.736