| Nome |
# |
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Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions, file 9d8a7c8c-0b46-46af-9139-591c548b171a
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190
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Radiosynthesis and in vivo Evaluation of Carbon-11 (2S)-3-(1H-Indol-3-yl)-2-[(4-methoxyphenyl)carbamoyl]amino-N-[1-(5-methoxypyridin-2-yl)cyclohexyl]methylpropanamide: An Attempt to Visualize Brain Formyl Peptide Receptors in Mouse Models of Neuroinflammation, file dd9e0c67-3dcd-1e9c-e053-3a05fe0a45ef
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123
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null, file dd9e0c6a-8949-1e9c-e053-3a05fe0a45ef
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122
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Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics., file dd9e0c67-0646-1e9c-e053-3a05fe0a45ef
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90
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Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update, file 985cba75-da48-4110-bf06-4c75fe07714b
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87
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The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK, file ddd2f1c8-551f-41cd-956e-3aaffed4f16e
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76
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Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome., file dd9e0c67-1e3e-1e9c-e053-3a05fe0a45ef
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71
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Activation of 5-HT7 receptor by administration of its selective agonist, LP-211, modifies explorative-curiosity behavior in rats in two paradigms which differ in visuospatial parameters, file dd9e0c67-14ca-1e9c-e053-3a05fe0a45ef
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66
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Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome, file dd9e0c67-3550-1e9c-e053-3a05fe0a45ef
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65
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Novel 64Cu Labeled RGD2-BBN Heterotrimers for PET Imaging of Prostate Cancer, file dd9e0c67-3a73-1e9c-e053-3a05fe0a45ef
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63
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Prior Activation of 5-HT7 Receptors Modulates the Conditioned Place Preference With Methylphenidate, file dd9e0c67-143e-1e9c-e053-3a05fe0a45ef
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56
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Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress, file dd9e0c67-0a02-1e9c-e053-3a05fe0a45ef
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55
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Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome, file dd9e0c67-14cf-1e9c-e053-3a05fe0a45ef
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52
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Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist, file 0e20997b-4c8d-43d5-b93c-f38c47e5ab15
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50
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Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice, file dd9e0c6a-b41d-1e9c-e053-3a05fe0a45ef
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45
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Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome, file 125162d0-f502-45c2-90cc-b31048bd6a9c
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40
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Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons, file e046dd17-4966-4e2b-bb37-f84780615573
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33
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The GR-127935-sensitive mechanism mediating hypotension in anesthetized rats: are 5-HT5B receptors involved?, file dd9e0c66-d7e1-1e9c-e053-3a05fe0a45ef
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21
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Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2, file b57f7f96-4a54-4f55-8aff-9a6c9209a91d
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12
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Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome, file dd9e0c66-d58f-1e9c-e053-3a05fe0a45ef
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6
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Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions, file dd9e0c66-f352-1e9c-e053-3a05fe0a45ef
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6
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LC–MS/MS Analysis on Infusion Bags and Filled Syringes of Decitabine: New Data on Physicochemical Stability of an Unstable Molecule, file 67c1933f-0286-4b2e-99e3-1d79135f2189
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5
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P-GP RADIOTRACER FOR IMAGING AS BIOMARKERS INVOLVED IN ONSET OF NEURODEGENERATIVE DISEASE, file dd9e0c63-a000-1e9c-e053-3a05fe0a45ef
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5
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Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist, file dd9e0c66-db15-1e9c-e053-3a05fe0a45ef
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5
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null, file dd9e0c65-df4a-1e9c-e053-3a05fe0a45ef
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4
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Structure-activity relationship study towards non-peptidic positron emission tomography (PET) radiotracer for gastrin releasing peptide receptors: Development of [18F] (S)-3-(1H-indol-3-yl)-N-[1-[5-(2-fluoroethoxy)pyridin-2-yl]cyclohexylmethyl]-2-methyl-2-[3-(4-nitrophenyl)ureido]propionamide., file dd9e0c66-e345-1e9c-e053-3a05fe0a45ef
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4
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Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons, file dd9e0c68-cd09-1e9c-e053-3a05fe0a45ef
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4
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Mitochondrial membranes of human SH-SY5Y neuroblastoma cells express serotonin 5-HT7 receptor, file 4ec7efcb-3a17-4f9f-8381-49aa1f22ecd4
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3
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Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update, file dd9e0c66-f408-1e9c-e053-3a05fe0a45ef
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3
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Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2, file dd9e0c67-2999-1e9c-e053-3a05fe0a45ef
|
3
|
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The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK, file dd9e0c67-3279-1e9c-e053-3a05fe0a45ef
|
3
|
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Multi‐target directed ligands (Mtdls) binding the σ1 receptor as promising therapeutics: State of the art and perspectives, file dd9e0c6b-bf0d-1e9c-e053-3a05fe0a45ef
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3
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The n-formyl peptide receptor 2 (Fpr2) agonist mr-39 exhibits anti-inflammatory activity in lps-stimulated organotypic hippocampal cultures, file f1ccffbc-d74c-4976-b290-0ef2412addca
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3
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Design and synthesis of new selective P-gp substrates and inhibitors., file dd9e0c63-e087-1e9c-e053-3a05fe0a45ef
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2
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An updated patent review on P-glycoprotein inhibitors (2011-2018), file dd9e0c66-d4d0-1e9c-e053-3a05fe0a45ef
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2
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Structural Determinants in the Binding of BB2 Receptor Ligands: In Silico, X-Ray and NMR Studies in PD176252 Analogues., file dd9e0c67-1190-1e9c-e053-3a05fe0a45ef
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2
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Functionalized Coumarine Fragment to Obtain Fluorescent and Selective P-Glycoprotein Ligands, file dd9e0c67-2610-1e9c-e053-3a05fe0a45ef
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2
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Radiofarmaci, file dd9e0c6a-9b21-1e9c-e053-3a05fe0a45ef
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2
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Low basicity as a characteristic for atypical ligands of serotonin receptor 5-HT2, file f618f118-81de-439f-bb8f-1c1b653ebb73
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2
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null, file 5b07bd71-0916-4725-8071-b53fc9f4e451
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1
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Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters, file dd9e0c63-bb1c-1e9c-e053-3a05fe0a45ef
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1
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A Benzopyrane derivative as P-glycoprotein stimulator: a potential agent to decrease beta-amyloid accumulation in Alzheimer’s disease, file dd9e0c64-f386-1e9c-e053-3a05fe0a45ef
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1
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Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments, file dd9e0c64-f389-1e9c-e053-3a05fe0a45ef
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1
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null, file dd9e0c64-f85c-1e9c-e053-3a05fe0a45ef
|
1
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Investigations on the 1-(2-biphenyl)piperazine motif. Identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo., file dd9e0c64-fce3-1e9c-e053-3a05fe0a45ef
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1
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Aurantiamide-related dipeptide derivatives are formyl peptide receptor 1 antagonists, file dd9e0c66-9783-1e9c-e053-3a05fe0a45ef
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1
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Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation, file dd9e0c66-d239-1e9c-e053-3a05fe0a45ef
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1
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Potentiation of capsaicin-induced neurogenic inflammation by 5-HT7 receptors in the rat hind paw: Involvement of calcitonin gen-related peptide, file dd9e0c66-d60e-1e9c-e053-3a05fe0a45ef
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1
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Stimulation of 5-HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas, file dd9e0c66-d893-1e9c-e053-3a05fe0a45ef
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1
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The brain-penetrant 5-HT7receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain, file dd9e0c66-e348-1e9c-e053-3a05fe0a45ef
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1
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Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder, file dd9e0c66-f3c4-1e9c-e053-3a05fe0a45ef
|
1
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5-HT7 receptor activation: procognitive and antiamnesic effects, file dd9e0c67-003f-1e9c-e053-3a05fe0a45ef
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1
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LP-211, a selective 5-HT7receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats, file dd9e0c67-134a-1e9c-e053-3a05fe0a45ef
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1
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The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology, file dd9e0c67-15fc-1e9c-e053-3a05fe0a45ef
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1
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ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth., file dd9e0c67-1ffb-1e9c-e053-3a05fe0a45ef
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1
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Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2., file dd9e0c67-200a-1e9c-e053-3a05fe0a45ef
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1
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Structural modifications of the serotonin 5-HT7 receptor agonist N -(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study, file dd9e0c67-2d39-1e9c-e053-3a05fe0a45ef
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1
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Structural insights into serotonin receptor ligands polypharmacology, file dd9e0c67-2fe8-1e9c-e053-3a05fe0a45ef
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1
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HPLC-UV and LC-MS/MS analysis to study formulation and long-term stability of some anticancer drugs in elastomeric pumps, file dd9e0c6a-5eaa-1e9c-e053-3a05fe0a45ef
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1
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null, file dd9e0c6a-5f85-1e9c-e053-3a05fe0a45ef
|
1
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Small and innovative molecules as new strategy to revert MDR, file dd9e0c6a-86e4-1e9c-e053-3a05fe0a45ef
|
1
|
| Totale |
1.408 |