PURGATORIO, ROSA
PURGATORIO, ROSA
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease
2022-01-01 Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease.
2021-01-01 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics
2024-01-01 Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells
2018-01-01 Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease
2019-01-01 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
A second life for MAO inhibitors? From CNS diseases to anticancer therapy
2024-01-01 Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.
Advances in synthesis of novel annulated azecines and their unique pharmacological properties
2024-01-01 Listratova, Anna V.; Samarelli, Francesco; Titov, Alexander A.; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Varlamov, Alexey V.; Voskressensky, Leonid G.; Altomare, Cosimo D.
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads.
2019-01-01 Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G.
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
2022-01-01 Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D.
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones
2010-01-01 Campagna, Francesco; Purgatorio, R; Catto, Marco; Carotti, A; De, Stradisa; Palazzo, Gerardo
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones
2010-01-01 Campagna, F; Purgatorio, R; Catto, M; Carotti, A; Stradisa, De; Palazzo, G
Biophysical characterization of inhibition of Aβ fibril formation by isatin-3-arylhydrazones
2010-01-01 Campagna, F; Purgatorio, R; Catto, Marco; Carotti, A; De Stradis, A; Palazzo, Gerardo
Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity
2023-01-01 Kulikova, Larisa N.; Purgatorio, Rosa; Beloglazkin, Andrey A.; Tafeenko, Viktor A.; Reza, Raesi Gh.; Levickaya, Daria D.; Sblano, Sabina; Boccarelli, Angelina; DE CANDIA, Modesto; Catto, Marco; Voskressensky, Leonid G.; Altomare, Cosimo D.
Coumarin Derivative Hybrids: Novel Dual Inhibitors Targeting Acetylcholinesterase and Monoamine Oxidases for Alzheimer’s Therapy
2024-01-01 Żołek, Teresa; Purgatorio, Rosa; Kłopotowski, Łukasz; Catto, Marco; Ostrowska, Kinga
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors
2010-01-01 Catto, Marco; Aliano, R; Carotti, Angelo; Cellamare, Saverio; Palluotto, Fausta; Purgatorio, R; DE STRADIS, A; Campagna, Francesco
Development of a continuous flow synthesis of propranolol: tackling a competitive side reaction
2019-01-01 De Angelis, S.; Celestini, P.; Purgatorio, R.; Degennaro, L.; Rebuzzini, G.; Luisi, R.; Carlucci, C.
Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase
2022-01-01 Bolognino, Isabella; Carrieri, Antonio; Purgatorio, Rosa; Catto, Marco; Caliandro, Rocco; Carrozzini, Benedetta; Belviso, BENNY DANILO; Majellaro, Maria; Sotelo, Eddy; Cellamare, Saverio; Altomare, Cosimo Damiano
Evaluation of Novel Guanidino-Containing Isonipecotamide Inhibitors of Blood Coagulation Factors against SARS-CoV-2 Virus Infection
2022-01-01 Maio, F. D.; Rullo, M.; de Candia, M.; Purgatorio, R.; Lopopolo, G.; Santarelli, G.; Palmieri, V.; Papi, M.; Elia, G.; De Candia, E.; Sanguinetti, M.; Altomare, C. D.
Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease
2021-01-01 Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Denora, Nunzio; Carrieri, Antonio; Nevskaya, Alisa A.; Voskressensky, Leonid G.; Altomare, Cosimo D.
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
2021-01-01 Purgatorio, Rosa; Gambacorta, Nicola; DE CANDIA, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Nicolotti, Orazio; Altomare, Cosimo Damiano
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
1,3,5-triazine derivatives as dual inhibitors of 5-HT6R/FAAH in search of new therapy for Alzheimer's disease | 1-gen-2022 | Czarnota-Łydka, Kinga; Satała, Grzegorz; Brunetti, Leonardo; Laghezza, Antonio; Piemontese, Luca; DE CANDIA, Modesto; Purgatorio, Rosa; Gumułka, Magdalena; Kucwaj-Brysz, Katarzyna; Carrieri, Antonio; Handzlik, Jadwiga | |
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. | 1-gen-2021 | Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D. | |
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics | 1-gen-2024 | Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano | |
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells | 1-gen-2018 | Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G. | |
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease | 1-gen-2019 | Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M | |
A second life for MAO inhibitors? From CNS diseases to anticancer therapy | 1-gen-2024 | Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D. | |
Advances in synthesis of novel annulated azecines and their unique pharmacological properties | 1-gen-2024 | Listratova, Anna V.; Samarelli, Francesco; Titov, Alexander A.; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Varlamov, Alexey V.; Voskressensky, Leonid G.; Altomare, Cosimo D. | |
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. | 1-gen-2019 | Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G. | |
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases | 1-gen-2022 | Purgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; DE CANDIA, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D. | |
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones | 1-gen-2010 | Campagna, Francesco; Purgatorio, R; Catto, Marco; Carotti, A; De, Stradisa; Palazzo, Gerardo | |
Biophysical Characterization of Inhibition of A-beta Fibril Formation by Isatin-3-arylhydrazones | 1-gen-2010 | Campagna, F; Purgatorio, R; Catto, M; Carotti, A; Stradisa, De; Palazzo, G | |
Biophysical characterization of inhibition of Aβ fibril formation by isatin-3-arylhydrazones | 1-gen-2010 | Campagna, F; Purgatorio, R; Catto, Marco; Carotti, A; De Stradis, A; Palazzo, Gerardo | |
Chemical and Biological Evaluation of Novel 1H-Chromeno[3,2-c]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity | 1-gen-2023 | Kulikova, Larisa N.; Purgatorio, Rosa; Beloglazkin, Andrey A.; Tafeenko, Viktor A.; Reza, Raesi Gh.; Levickaya, Daria D.; Sblano, Sabina; Boccarelli, Angelina; DE CANDIA, Modesto; Catto, Marco; Voskressensky, Leonid G.; Altomare, Cosimo D. | |
Coumarin Derivative Hybrids: Novel Dual Inhibitors Targeting Acetylcholinesterase and Monoamine Oxidases for Alzheimer’s Therapy | 1-gen-2024 | Żołek, Teresa; Purgatorio, Rosa; Kłopotowski, Łukasz; Catto, Marco; Ostrowska, Kinga | |
Design, synthesis and biological evaluation of indane 2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as b-amyloid aggregation inhibitors | 1-gen-2010 | Catto, Marco; Aliano, R; Carotti, Angelo; Cellamare, Saverio; Palluotto, Fausta; Purgatorio, R; DE STRADIS, A; Campagna, Francesco | |
Development of a continuous flow synthesis of propranolol: tackling a competitive side reaction | 1-gen-2019 | De Angelis, S.; Celestini, P.; Purgatorio, R.; Degennaro, L.; Rebuzzini, G.; Luisi, R.; Carlucci, C. | |
Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase | 1-gen-2022 | Bolognino, Isabella; Carrieri, Antonio; Purgatorio, Rosa; Catto, Marco; Caliandro, Rocco; Carrozzini, Benedetta; Belviso, BENNY DANILO; Majellaro, Maria; Sotelo, Eddy; Cellamare, Saverio; Altomare, Cosimo Damiano | |
Evaluation of Novel Guanidino-Containing Isonipecotamide Inhibitors of Blood Coagulation Factors against SARS-CoV-2 Virus Infection | 1-gen-2022 | Maio, F. D.; Rullo, M.; de Candia, M.; Purgatorio, R.; Lopopolo, G.; Santarelli, G.; Palmieri, V.; Papi, M.; Elia, G.; De Candia, E.; Sanguinetti, M.; Altomare, C. D. | |
Evaluation of water‐soluble Mannich base prodrugs of 2,3,4,5‐tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as multitarget‐directed agents for Alzheimer’s disease | 1-gen-2021 | Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Denora, Nunzio; Carrieri, Antonio; Nevskaya, Alisa A.; Voskressensky, Leonid G.; Altomare, Cosimo D. | |
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease | 1-gen-2021 | Purgatorio, Rosa; Gambacorta, Nicola; DE CANDIA, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Nicolotti, Orazio; Altomare, Cosimo Damiano |