Epidemiological trends of the globally most common rotavirus genotype, G1P[8], were investigated in Hungary during a 16-year period by sequencing and phylogenetic analysis of the surface antigens. Antigen shift among epidemiologically major G1P[8] strains was observed in 6 seasons, as indicated by changes in the sublineages of the G1 VP7 and the P[8] VP4 genes. The temporal clustering of some rotavirus VP4 and VP7 gene sublineages and the periodic emergence and/or resurgence of previously unrecognized rotavirus sublineages in the study population suggest a dynamic nature for these common strains. Recently established international strain surveillance networks may help to identify and track the spread of epidemiologically important rotavirus strains across countries and continents
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Titolo: | Trends in epidemiology of human P[8],G1 rotaviruses: a Hungarian study |
Autori: | |
Data di pubblicazione: | 2009 |
Rivista: | |
Handle: | http://hdl.handle.net/11586/9942 |
Appare nelle tipologie: | 1.1 Articolo in rivista |