Objectives/Introduction: To evaluate whether quantitative acti- graphic analysis is able to distinguish isolated REM sleep behavior disorder (iRBD) patients from patients suffering sleep disorders with pathological motor activity during sleep and healthy controls. Methods: 19 subjects with iRBD, 19 restless leg syndrome pa- tients (RLS), 20 untreated sleep apnea syndrome patients (OSA) and 16 healthy controls underwent 2-week actigraphy, video- polysomnography, and completed several RBD questionnaires. Results: iRBD patients have lower sleep efficiency (q < 0.05) with increased frequency of prolonged awakenings (q < 0.05) compared to RLS and controls. iRBD patients have more diurnal naps in com- parison to all clinical groups and to controls (q < 0.005). Actigraphic nonparametric measures not differ between iRBD patients and the other groups. A 24-hr measure that expresses the relationship be- tween nocturnal and diurnal motor activity intensity (I < O) well dis- tinguishes iRBD from other sleep disorders (q < 0.0005). Conclusions: Our results indicate that actigraphic assessment may have a relevant role in the diagnostic work up of iRBD. Actigraphy analysis, alone or in combination with other tools (e.g. screen- ing questionnaires), could represent an effective and easy-to-use screening tool for iRBD. Disclosure: Nothing to disclose.
Quantitative actigraphic analysis in isolated REM sleep behavior disorder
Marco Filardi;
2020-01-01
Abstract
Objectives/Introduction: To evaluate whether quantitative acti- graphic analysis is able to distinguish isolated REM sleep behavior disorder (iRBD) patients from patients suffering sleep disorders with pathological motor activity during sleep and healthy controls. Methods: 19 subjects with iRBD, 19 restless leg syndrome pa- tients (RLS), 20 untreated sleep apnea syndrome patients (OSA) and 16 healthy controls underwent 2-week actigraphy, video- polysomnography, and completed several RBD questionnaires. Results: iRBD patients have lower sleep efficiency (q < 0.05) with increased frequency of prolonged awakenings (q < 0.05) compared to RLS and controls. iRBD patients have more diurnal naps in com- parison to all clinical groups and to controls (q < 0.005). Actigraphic nonparametric measures not differ between iRBD patients and the other groups. A 24-hr measure that expresses the relationship be- tween nocturnal and diurnal motor activity intensity (I < O) well dis- tinguishes iRBD from other sleep disorders (q < 0.0005). Conclusions: Our results indicate that actigraphic assessment may have a relevant role in the diagnostic work up of iRBD. Actigraphy analysis, alone or in combination with other tools (e.g. screen- ing questionnaires), could represent an effective and easy-to-use screening tool for iRBD. Disclosure: Nothing to disclose.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
