Active antibody-mediated rejection is the main cause of kidney transplant loss, sharing with SLE the alloimmune response and the systemic activation of the IFN-α pathway. IgE-mediated immune response plays a key role in the development of SLE nephritis and is associated with IFN-α secretion. The aim of our study was to investigate IgE-mediated immune response in antibody-mediated rejection.
IgE-Mediated Immune Response and Antibody-Mediated Rejection
Rascio, Federica;Pontrelli, Paola
;Simone, Simona;Ranieri, Elena;Gesualdo, Loreto;Stallone, Giovanni;Grandaliano, Giuseppe
2020-01-01
Abstract
Active antibody-mediated rejection is the main cause of kidney transplant loss, sharing with SLE the alloimmune response and the systemic activation of the IFN-α pathway. IgE-mediated immune response plays a key role in the development of SLE nephritis and is associated with IFN-α secretion. The aim of our study was to investigate IgE-mediated immune response in antibody-mediated rejection.File in questo prodotto:
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