Background: The cancer disease is the clinical condition most often associated with the concept of protein-calorie malnutrition that affects 8% to 84% of cancer patients and can worsen until determining cachexia also called “Wasting Disease”. Cancer-Related Anorexia-Cachexia Syndrome (CACS), is a complex metabolic syndrome characterized by a negative protein balance and energy caused both by a reduced caloric intake from both metabolic abnormalities associated with loss of muscle mass with or without loss of mass fat and considerable weight loss; it is estimated that about 20% of all cancer deaths occur for malnutrition. It is necessary to complement clinical examination of the patient also with review the nutritional status in order to evaluate the therapeutic process in these patients. Objective: The aim of this study was to assess the prevalence of malnutrition or the risk of malnutrition in patients undergoing to surgery for colorectal carcinoma. Methods: A total of 53 patients, 26 male and 27 female media age: 70,5 (42-86 yrs) undergoing to surgery for colorectal carcinoma in our Institute between November 2014 and April 2015, were evaluated to determine individual nutritional status, using the Mini Nutritional Assessment (MNA®) that includes 18 items grouped in four rubrics: anthropometric assessment, general assessment and lifestyle, short dietary assessment and subjective perception of health and nutrition. Results: The overall mean score for the MNA, was 26.2 ± 13.2 (range 6.0-27.0);15/53 patients (24.5%) presented a normal nutritional status (mean 24.8; range 24.0 to 27.5),25/53 (47%) reported a risk of malnutrition while 13/53 (24.5%) reported a severemalnutrition that was found to be more common in men than in women. Besides, allmalnourished patients had in the previous six months from the date of diagnosis, asignificant weight loss (> 10 kg), muscle mass loss and severe reduction in the intake of food due loss of appetite and altered taste perception. Instead, patients at risk for malnutrition reported a weight loss of 3 to 5 kg and a moderate reduction in food intake. Conclusions: More than 50% of patients had moderate or severe malnutrition and the majority of them needed nutritional intervention before and during chemotherapy. Our preliminary data show the importance of nutritional assessment in cancer patients in order to set the appropriate treatment plan, improve its quality of life and increase overall survival in cancer patient.
Use of The Mini Nutritional Assessment to determine the Prevalence of Malnutrition And Cachexia In Patients Undergoing Surgery For Colorectal Carcinoma
MALLAMACI, Rosanna;
2015-01-01
Abstract
Background: The cancer disease is the clinical condition most often associated with the concept of protein-calorie malnutrition that affects 8% to 84% of cancer patients and can worsen until determining cachexia also called “Wasting Disease”. Cancer-Related Anorexia-Cachexia Syndrome (CACS), is a complex metabolic syndrome characterized by a negative protein balance and energy caused both by a reduced caloric intake from both metabolic abnormalities associated with loss of muscle mass with or without loss of mass fat and considerable weight loss; it is estimated that about 20% of all cancer deaths occur for malnutrition. It is necessary to complement clinical examination of the patient also with review the nutritional status in order to evaluate the therapeutic process in these patients. Objective: The aim of this study was to assess the prevalence of malnutrition or the risk of malnutrition in patients undergoing to surgery for colorectal carcinoma. Methods: A total of 53 patients, 26 male and 27 female media age: 70,5 (42-86 yrs) undergoing to surgery for colorectal carcinoma in our Institute between November 2014 and April 2015, were evaluated to determine individual nutritional status, using the Mini Nutritional Assessment (MNA®) that includes 18 items grouped in four rubrics: anthropometric assessment, general assessment and lifestyle, short dietary assessment and subjective perception of health and nutrition. Results: The overall mean score for the MNA, was 26.2 ± 13.2 (range 6.0-27.0);15/53 patients (24.5%) presented a normal nutritional status (mean 24.8; range 24.0 to 27.5),25/53 (47%) reported a risk of malnutrition while 13/53 (24.5%) reported a severemalnutrition that was found to be more common in men than in women. Besides, allmalnourished patients had in the previous six months from the date of diagnosis, asignificant weight loss (> 10 kg), muscle mass loss and severe reduction in the intake of food due loss of appetite and altered taste perception. Instead, patients at risk for malnutrition reported a weight loss of 3 to 5 kg and a moderate reduction in food intake. Conclusions: More than 50% of patients had moderate or severe malnutrition and the majority of them needed nutritional intervention before and during chemotherapy. Our preliminary data show the importance of nutritional assessment in cancer patients in order to set the appropriate treatment plan, improve its quality of life and increase overall survival in cancer patient.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
