Comparative oncology has recently developed, in according to the quality of scientific research, as the result of reasonable opportunity to study neoplastic diseases in the pets "dogs and cats" that may provide new biological information and knowledge for the understanding and treatment of human cancers.Some spontaneous tumors of animals, such as mammary (breast),lymphohematopoietic, cutaneous (mastocytoma) and vescical, are considered models that share, with human cancers, biological aspects in terms of carcinogenesis and tumor progression and clinical aspects; thus, comes the need to preserve biological material in optimal condition and their associated data, in order to have a tissue heritage to be exploited over time to new insights and innovative laboratory techniques. The Faculty of Veterinary Medicine, University of Bari has signed an agreement with I.R.C.C.S Istituto Tumori "Giovanni Paolo II" di Bari to assist in the creation of an animal tissue-bank to collect samples of neoplastic organs. The collection, preservation and recording of biological sample are made according to a system of operating procedures (SOPs) and addressed to ensure common quality standards. The specimen is initially stored at the Faculty of Veterinary Medicine, then moved in accordance with procedures involving biological material transfer mode to I.R.C.C.S where a biobank institutional functioning. Is designing a computerized system for data management that meets the needs of the two structures. The samples data are currently recorded in the register "Comparative Biobank" and inserted into a database. For appropriate management the staff of both facilities has been instructed in order to have a unique mode of approach to research. The collaboration has developed national and international projects aimed at theme of the VEGF, Thymidine Phosphorylase, Ki-67 on different animal species tumors.

Biobanks in Veterinary Oncology as a resource for Transactional research

ZIZZO, Nicola;PASSANTINO, Giuseppe;
2011-01-01

Abstract

Comparative oncology has recently developed, in according to the quality of scientific research, as the result of reasonable opportunity to study neoplastic diseases in the pets "dogs and cats" that may provide new biological information and knowledge for the understanding and treatment of human cancers.Some spontaneous tumors of animals, such as mammary (breast),lymphohematopoietic, cutaneous (mastocytoma) and vescical, are considered models that share, with human cancers, biological aspects in terms of carcinogenesis and tumor progression and clinical aspects; thus, comes the need to preserve biological material in optimal condition and their associated data, in order to have a tissue heritage to be exploited over time to new insights and innovative laboratory techniques. The Faculty of Veterinary Medicine, University of Bari has signed an agreement with I.R.C.C.S Istituto Tumori "Giovanni Paolo II" di Bari to assist in the creation of an animal tissue-bank to collect samples of neoplastic organs. The collection, preservation and recording of biological sample are made according to a system of operating procedures (SOPs) and addressed to ensure common quality standards. The specimen is initially stored at the Faculty of Veterinary Medicine, then moved in accordance with procedures involving biological material transfer mode to I.R.C.C.S where a biobank institutional functioning. Is designing a computerized system for data management that meets the needs of the two structures. The samples data are currently recorded in the register "Comparative Biobank" and inserted into a database. For appropriate management the staff of both facilities has been instructed in order to have a unique mode of approach to research. The collaboration has developed national and international projects aimed at theme of the VEGF, Thymidine Phosphorylase, Ki-67 on different animal species tumors.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/148219
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