Handwritten processing for Pre Diagnosis of Alzheimer disease

Based on neuromuscular transfer function of the handwriting system, in this paper a non invasive pre diagnosis system for Alzheimer disease alert is proposed. It is well known in fact, that writing originates from spike trains produced within the Central Nervous System (CNS) and more specifically, inside the 4-th and the 6-th regions of the Bradman's map and then transmitted through the first and second order axons to the spinal cord to control the muscles involved in the handwriting as the arm, the forearm, the hand and the pen or pencil utilized for the writing. More specifically, in this work is proposed a new method, not invasive, for early diagnosis of degenerative disability, it can be also useful for monitoring activities related to the progression of neuromuscular disease in order to evaluate the changing related also to the efficiency of the therapies used. Benefit can be obtained not only for the medical field but also for the pharmaceutical developments. Specifically in the paper, the results of some experiments have been focused by considering a certain number of persons some of which affect by Alzheimer disease.