Four canine coronavirus type II (CCoV-II) strains were identified in the guts and internal organs of pups which had died of acute gastroenteritis. The CCoV-II strains were strictly related to porcine transmissible gastroenteritis virus (TGEV) in the N-terminal domain of the spike protein, whereas in the other parts of the genome, a higher genetic relatedness to recent CCoV-II isolates was observed. Experimental infection of dogs with a TGEV-like isolate induced mild gastroenteritis without any systemic involvement. By virus neutralization tests, antigenic differences between reference and TGEV-like CCoVs were found. Our data support the potential recombinant origin of the TGEV-like CCoVs.
Scheda prodotto non validato
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
|Titolo:||Recombinant canine coronaviruses related to transmissible gastroenteritis virus of swine are circulating in dogs|
|Data di pubblicazione:||2009|
|Citazione:||Recombinant canine coronaviruses related to transmissible gastroenteritis virus of swine are circulating in dogs / Decaro, N; Mari, V; Campolo, M; Lorusso, A; Camero, M; Elia, G; Martella, V; Cordioli, P; Enjuanes, L; Buonavoglia, C. - In: JOURNAL OF VIROLOGY. - ISSN 0022-538X. - 83(2009), pp. 1532-1537.|
|Appare nelle tipologie:||1.1 Articolo in rivista|