MICIACCIA, MORENA
MICIACCIA, MORENA
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior
2024-01-01 Solidoro, Roberta; Miciaccia, Morena; Bonaccorso, Carmela; Fortuna, Cosimo Gianluca; Armenise, Domenico; Centonze, Antonella; Ferorelli, Savina; Vitale, Paola; Rodrigues, Pryscila; Guimarães, Renilda; de Oliveira, Alana; da Paz, Mariana; Rangel, Luciana; Sathler, Plínio Cunha; Altomare, Angela; Perrone, Maria Grazia; Scilimati, Antonio
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition
2022-01-01 Perrone, M. G.; Miciaccia, M.; Ferorelli, S.; Scilimati, A.
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid
2021-01-01 Perrone, M. G.; Miciaccia, M.; Vitale, P.; Ferorelli, S.; Araujo, C. D. C. B.; de Almeida, G. S.; Souza Domingos, T. F.; da Silva, L. C. R. P.; de Padula, M.; Cabral, L. M.; Sathler, P. C.; Bonaccorso, C.; Fortuna, C. G.; Scilimati, A.
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER
2022-01-01 Scilimati, A.; Ferorelli, S.; Centonze, A.; Miciaccia, M.; Solidoro, R.; De Grassi, A.; Perrone, M. G.
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes
2021-01-01 Miciaccia, M.; Belviso, B. D.; Caliandro, R.; Ferorelli, S.; Perrone, M. G.; Scilimati, A.
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19
2022-01-01 Solidoro, R.; Armenise, D.; Ferorelli, S.; Miciaccia, M.; Perrone, M. G.; Scilimati, A
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders
2020-01-01 Perrone, M. G.; Centonze, A.; Miciaccia, M.; Ferorelli, S.; Scilimati, A.
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer
2023-01-01 Miciaccia, Morena; Ferorelli, Savina; Centonze, Antonella; Solidoro, Roberta; Munzone, Cristina; Bonaccorso, Carmela; Gianluca Fortuna, Cosimo; Kleinmanns, Katrin; Bjørge, Line; Perrone, MARIA GRAZIA; Scilimati, Antonio
Design and synthesis of new [4,5-b] and [4,5-c] imidazopyridines as potential fluorophores/inhibitors for Human Cyclooxygenase-1.
2023-01-01 Munzone, C.; Fortuna, C. G.; Bonaccorso, C.; Perrone, M. G.; Miciaccia, M.
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug.
2023-01-01 Scilimati, Antonio; Armenise, Domenico; Baldelli, Olga; Centonze, Antonella; Derri, Davide; Ferorelli, Savina; Miciaccia, Morena; Solidoro, Roberta; Perrone, MARIA GRAZIA
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery
2024-01-01 Solidoro, Roberta; Centonze, Antonella; Miciaccia, Morena; Baldelli, Olga Maria; Armenise, Domenico; Ferorelli, Savina; Perrone, Maria Grazia; Scilimati, Antonio
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes
2022-01-01 Perrone, Maria Grazia; Vitale, Paola; Miciaccia, Morena; Ferorelli, Savina; Centonze, Antonella; Solidoro, Roberta; Munzone, Cristina; Bonaccorso, Carmela; Fortuna, Cosimo Gianluca; Kleinmanns, Katrin; Bjørge, Line; Scilimati, Antonio
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment
2024-01-01 Miciaccia, Morena; Rizzo, Francesca; Centonze, Antonella; Cavallaro, Gianfranco; Contino, Marialessandra; Armenise, Domenico; Baldelli, OLGA MARIA; Solidoro, Roberta; Ferorelli, Savina; Scarcia, Pasquale; Agrimi, Gennaro; Zingales, Veronica; Cimetta, Elisa; Ronsisvalle, Simone; Maria Sipala, Federica; LOGUERCIO POLOSA, Paola Anna Maria; Gianluca Fortuna, Cosimo; Perrone, MARIA GRAZIA; Scilimati, Antonio
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment
2023-01-01 Miciaccia, Morena; Centonze, Antonella; Baldelli, Olga; Solidoro, Roberta; Armenise, Domenico; Cavallaro, Gianfranco; Gianluca Fortuna, Cosimo; Ferorelli, Savina; Perrone, MARIA GRAZIA; Scilimati, Antonio
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG
2023-01-01 Perrone, M. G.; Centonze, A.; Miciaccia, M.; Baldelli, O.; Cavallaro, G.; Ferorelli, S.; Fortuna, C.; Scilimati, A.
Inside circular economy challenges: “green” application to valorise olive mill wastewater
2022-01-01 Foti, Paola; Occhipinti, Paride S.; Russo, Nunziatina; Scilimati, Antonio; Miciaccia, Morena; Ferorelli, Savina; Caggia, Cinzia; Perrone, MARIA GRAZIA; Randazzo, Cinzia L.; Romeo, Flora V.
Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design
2021-01-01 Friedrich, L.; Cingolani, G.; Ko, Y. -H.; Iaselli, M.; Miciaccia, M.; Perrone, M. G.; Neukirch, K.; Bobinger, V.; Merk, D.; Hofstetter, R. K.; Werz, O.; Koeberle, A.; Scilimati, A.; Schneider, G.
m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity
2023-01-01 Rocchi, Damiano; González, Juan F.; Martín-Cámara, Olmo; Perrone, MARIA GRAZIA; Miciaccia, Morena; Scilimati, Antonio; Decouty-Pérez, Celine; Parada, Esther; Egea, Javier; Carlos Menéndez, J.
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer
2023-01-01 Rizzo, Francesca; Miciaccia, Morena; Cormio, Antonella; Ferorelli, Savina; Perrone, MARIA GRAZIA; Scilimati, Antonio; LOGUERCIO POLOSA, Paola Anna Maria
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT
2022-01-01 Miciaccia, M.; Ferorelli, S.; Scarcia, P.; Carrieri, A.; Rizzo, F.; Loguercio Polosa, P.; Perrone, M. G.; Scilimati, A.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior | 1-gen-2024 | Solidoro, Roberta; Miciaccia, Morena; Bonaccorso, Carmela; Fortuna, Cosimo Gianluca; Armenise, Domenico; Centonze, Antonella; Ferorelli, Savina; Vitale, Paola; Rodrigues, Pryscila; Guimarães, Renilda; de Oliveira, Alana; da Paz, Mariana; Rangel, Luciana; Sathler, Plínio Cunha; Altomare, Angela; Perrone, Maria Grazia; Scilimati, Antonio | |
A Simplified Direct O2 Consumption-Based Assay to Test COX Inhibition | 1-gen-2022 | Perrone, M. G.; Miciaccia, M.; Ferorelli, S.; Scilimati, A. | |
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid | 1-gen-2021 | Perrone, M. G.; Miciaccia, M.; Vitale, P.; Ferorelli, S.; Araujo, C. D. C. B.; de Almeida, G. S.; Souza Domingos, T. F.; da Silva, L. C. R. P.; de Padula, M.; Cabral, L. M.; Sathler, P. C.; Bonaccorso, C.; Fortuna, C. G.; Scilimati, A. | |
CHALLENGE TRANSABILITY OF “IN VITRO” TO “IN VIVO”: GENE-EXPRESSION BIOMARKERS AND FLUORESCENT IMAGE-GUIDED SURGERY PROBES IDENTIFICATION FOR OVARIAN CANCER | 1-gen-2022 | Scilimati, A.; Ferorelli, S.; Centonze, A.; Miciaccia, M.; Solidoro, R.; De Grassi, A.; Perrone, M. G. | |
Comparative Structural Analysis of hCOX‑1 and oCOX‑1 Isoenzymes | 1-gen-2021 | Miciaccia, M.; Belviso, B. D.; Caliandro, R.; Ferorelli, S.; Perrone, M. G.; Scilimati, A. | |
COX-1 INHIBITORS AS ANTI-PLATELET AGENTS IN COVID-19 | 1-gen-2022 | Solidoro, R.; Armenise, D.; Ferorelli, S.; Miciaccia, M.; Perrone, M. G.; Scilimati, A | |
Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders | 1-gen-2020 | Perrone, M. G.; Centonze, A.; Miciaccia, M.; Ferorelli, S.; Scilimati, A. | |
Cyclooxygenase-1 Inhibition: A Promising Theragnostic Approach for Ovarian Cancer | 1-gen-2023 | Miciaccia, Morena; Ferorelli, Savina; Centonze, Antonella; Solidoro, Roberta; Munzone, Cristina; Bonaccorso, Carmela; Gianluca Fortuna, Cosimo; Kleinmanns, Katrin; Bjørge, Line; Perrone, MARIA GRAZIA; Scilimati, Antonio | |
Design and synthesis of new [4,5-b] and [4,5-c] imidazopyridines as potential fluorophores/inhibitors for Human Cyclooxygenase-1. | 1-gen-2023 | Munzone, C.; Fortuna, C. G.; Bonaccorso, C.; Perrone, M. G.; Miciaccia, M. | |
DIPG-27. Diffuse Intrinsic Pontine Glioma (DIPG) challenge: from gene expression profile to drug. | 1-gen-2023 | Scilimati, Antonio; Armenise, Domenico; Baldelli, Olga; Centonze, Antonella; Derri, Davide; Ferorelli, Savina; Miciaccia, Morena; Solidoro, Roberta; Perrone, MARIA GRAZIA | |
Fluorescent imaging probes for in vivo ovarian cancer targeted detection and surgery | 1-gen-2024 | Solidoro, Roberta; Centonze, Antonella; Miciaccia, Morena; Baldelli, Olga Maria; Armenise, Domenico; Ferorelli, Savina; Perrone, Maria Grazia; Scilimati, Antonio | |
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes | 1-gen-2022 | Perrone, Maria Grazia; Vitale, Paola; Miciaccia, Morena; Ferorelli, Savina; Centonze, Antonella; Solidoro, Roberta; Munzone, Cristina; Bonaccorso, Carmela; Fortuna, Cosimo Gianluca; Kleinmanns, Katrin; Bjørge, Line; Scilimati, Antonio | |
Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment | 1-gen-2024 | Miciaccia, Morena; Rizzo, Francesca; Centonze, Antonella; Cavallaro, Gianfranco; Contino, Marialessandra; Armenise, Domenico; Baldelli, OLGA MARIA; Solidoro, Roberta; Ferorelli, Savina; Scarcia, Pasquale; Agrimi, Gennaro; Zingales, Veronica; Cimetta, Elisa; Ronsisvalle, Simone; Maria Sipala, Federica; LOGUERCIO POLOSA, Paola Anna Maria; Gianluca Fortuna, Cosimo; Perrone, MARIA GRAZIA; Scilimati, Antonio | |
Harmaline-based scaffold as Human Caseinolytic Protease P (hClpP) inducers for Diffuse Intrinsic Pontine Glioma (DIPG) treatment | 1-gen-2023 | Miciaccia, Morena; Centonze, Antonella; Baldelli, Olga; Solidoro, Roberta; Armenise, Domenico; Cavallaro, Gianfranco; Gianluca Fortuna, Cosimo; Ferorelli, Savina; Perrone, MARIA GRAZIA; Scilimati, Antonio | |
Human Caseinolytic Protease P (hClpP) Activity Modulating Agents For The Treatment Of DIPG/DMG | 1-gen-2023 | Perrone, M. G.; Centonze, A.; Miciaccia, M.; Baldelli, O.; Cavallaro, G.; Ferorelli, S.; Fortuna, C.; Scilimati, A. | |
Inside circular economy challenges: “green” application to valorise olive mill wastewater | 1-gen-2022 | Foti, Paola; Occhipinti, Paride S.; Russo, Nunziatina; Scilimati, Antonio; Miciaccia, Morena; Ferorelli, Savina; Caggia, Cinzia; Perrone, MARIA GRAZIA; Randazzo, Cinzia L.; Romeo, Flora V. | |
Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design | 1-gen-2021 | Friedrich, L.; Cingolani, G.; Ko, Y. -H.; Iaselli, M.; Miciaccia, M.; Perrone, M. G.; Neukirch, K.; Bobinger, V.; Merk, D.; Hofstetter, R. K.; Werz, O.; Koeberle, A.; Scilimati, A.; Schneider, G. | |
m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity | 1-gen-2023 | Rocchi, Damiano; González, Juan F.; Martín-Cámara, Olmo; Perrone, MARIA GRAZIA; Miciaccia, Morena; Scilimati, Antonio; Decouty-Pérez, Celine; Parada, Esther; Egea, Javier; Carlos Menéndez, J. | |
Modulation of the activity of human mitochondrial protease complex ClpXP as potential therapeutic strategy for cancer | 1-gen-2023 | Rizzo, Francesca; Miciaccia, Morena; Cormio, Antonella; Ferorelli, Savina; Perrone, MARIA GRAZIA; Scilimati, Antonio; LOGUERCIO POLOSA, Paola Anna Maria | |
MODULATORS OF HUMAN MITOCHONDRIAL PROTEASE ClpP ACTIVITY FOR PEDIATRIC DIFFUSE PONTINE GLIOMA TREATMENT | 1-gen-2022 | Miciaccia, M.; Ferorelli, S.; Scarcia, P.; Carrieri, A.; Rizzo, F.; Loguercio Polosa, P.; Perrone, M. G.; Scilimati, A. |