NISO, MAURO
NISO, MAURO
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1
2019-01-01 Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco
2-Aminopyridine derivatives as potential sigma2 receptor antagonists
2012-01-01 Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance
2019-01-01 Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D.
4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators
2008-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Cantore, Mariangela; Perrone, MARIA GRAZIA; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto; Azzariti, Amalia; Simone, Grazia Maria; Paradiso, Angelo
4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes
2015-01-01 Schininà, B; Martorana, A; Colabufo, Nicola Antonio; Contino, Marialessandra; Niso, Mauro; Perrone, MARIA GRAZIA; de Guidi, G; Catalfo, A; Rappazzo, G; Zuccarello, E; Prezzavento, O; Amata, E; Rescifina, A; Marrazzo, A.
A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease
2012-01-01 Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A.
A Benzopyrane derivative as P-glycoprotein stimulator: a potential agent to decrease beta-amyloid accumulation in Alzheimer’s disease
2012-01-01 Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A.
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells
2018-01-01 Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G.
Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto
Antiproliferative and cytotoxic effects of some sigma-2 agonists and sigma-1 antagonists in tumour cell lines
2004-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Niso, Mauro; Abate, CARMEN rosa; Perrone, Roberto; Tortorella, V.
Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2
2015-01-01 Stroth, Nikolas; Niso, Mauro; Colabufo, Nicola Antonio; Perrone, Roberto; Svenningsson, Per; Lacivita, Enza; Leopoldo, Marcello
Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins
2008-01-01 Colabufo, Nicola Antonio; Pagliarulo, Vincenzo; Berardi, Francesco; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Ancona, Patrizia; Albo, Giancarlo; Pagliarulo, Arcangelo; Perrone, Roberto
Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: Synthesis and binding affinities for 5-HT7 and 5-HT1A receptors
2007-01-01 Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola Antonio; Niso, Mauro; Berardi, Francesco; Perrone, Roberto
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration
2020-01-01 Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra
Collateral Sensitivity of sigma2 Receptor ligands: Potentials in the Treatment of Multidrug Resistant Tumors
2014-01-01 Niso, Mauro; Chiara, Riganti; Abate, CARMEN rosa
Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer
2006-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Ferorelli, Savina; Niso, Mauro; Perrone, Roberto; Pagliarulo, Arcangelo; Saponaro, Pasquale; Pagliarulo, Vincenzo
Cyclohexylpiperazine derivative PB28, a σ2 agonist and σ1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer
2006-01-01 Azzariti, Amalia; Colabufo, Nicola Antonio; Berardi, Francesco; Porcelli, Letizia; Niso, Mauro; Simone, Grazia M.; Perrone, Roberto; Paradiso, Angelo
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells
2023-01-01 Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents
2015-01-01 Pati, MARIA LAURA; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Luisi, Renzo; Laura, Carroccia; Niso, Mauro; Berardi, Francesco
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1 | 1-gen-2019 | Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano | |
| 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco | |
| 2-Aminopyridine derivatives as potential sigma2 receptor antagonists | 1-gen-2012 | Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco | |
| 3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance | 1-gen-2019 | Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D. | |
| 4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators | 1-gen-2008 | Colabufo, Nicola Antonio; Berardi, Francesco; Cantore, Mariangela; Perrone, MARIA GRAZIA; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto; Azzariti, Amalia; Simone, Grazia Maria; Paradiso, Angelo | |
| 4-Nitro-2,1,3-benzoxadiazole derivatives as potential fluorescent sigma receptor probes | 1-gen-2015 | Schininà, B; Martorana, A; Colabufo, Nicola Antonio; Contino, Marialessandra; Niso, Mauro; Perrone, MARIA GRAZIA; de Guidi, G; Catalfo, A; Rappazzo, G; Zuccarello, E; Prezzavento, O; Amata, E; Rescifina, A; Marrazzo, A. | |
| A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease | 1-gen-2012 | Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A. | |
| A Benzopyrane derivative as P-glycoprotein stimulator: a potential agent to decrease beta-amyloid accumulation in Alzheimer’s disease | 1-gen-2012 | Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A. | |
| A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells | 1-gen-2018 | Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G. | |
| Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto | |
| Antiproliferative and cytotoxic effects of some sigma-2 agonists and sigma-1 antagonists in tumour cell lines | 1-gen-2004 | Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Niso, Mauro; Abate, CARMEN rosa; Perrone, Roberto; Tortorella, V. | |
| Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2 | 1-gen-2015 | Stroth, Nikolas; Niso, Mauro; Colabufo, Nicola Antonio; Perrone, Roberto; Svenningsson, Per; Lacivita, Enza; Leopoldo, Marcello | |
| Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins | 1-gen-2008 | Colabufo, Nicola Antonio; Pagliarulo, Vincenzo; Berardi, Francesco; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Ancona, Patrizia; Albo, Giancarlo; Pagliarulo, Arcangelo; Perrone, Roberto | |
| Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: Synthesis and binding affinities for 5-HT7 and 5-HT1A receptors | 1-gen-2007 | Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola Antonio; Niso, Mauro; Berardi, Francesco; Perrone, Roberto | |
| Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration | 1-gen-2020 | Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra | |
| Collateral Sensitivity of sigma2 Receptor ligands: Potentials in the Treatment of Multidrug Resistant Tumors | 1-gen-2014 | Niso, Mauro; Chiara, Riganti; Abate, CARMEN rosa | |
| Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer | 1-gen-2006 | Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Ferorelli, Savina; Niso, Mauro; Perrone, Roberto; Pagliarulo, Arcangelo; Saponaro, Pasquale; Pagliarulo, Vincenzo | |
| Cyclohexylpiperazine derivative PB28, a σ2 agonist and σ1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer | 1-gen-2006 | Azzariti, Amalia; Colabufo, Nicola Antonio; Berardi, Francesco; Porcelli, Letizia; Niso, Mauro; Simone, Grazia M.; Perrone, Roberto; Paradiso, Angelo | |
| Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells | 1-gen-2023 | Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen | |
| Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents | 1-gen-2015 | Pati, MARIA LAURA; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Luisi, Renzo; Laura, Carroccia; Niso, Mauro; Berardi, Francesco |