PISANI, LEONARDO

PISANI, LEONARDO  

DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO  

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Titolo Data di pubblicazione Autore(i) File
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 1-gen-2014 Cellamare, Saverio; Carotti, Angelo; Stefanachi, Angela; Leonetti, Francesco; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Tardia, Piero; Introcaso, Antonellina; Valentina, Leo; Addabbo, Francesco; Montagnani, Monica; Nacci, Carmela
1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1 1-gen-2019 Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance 1-gen-2019 Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. 1-gen-2021 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
4-(ALKYL)AMINOMETHYL-SUBSTITUTED COUMARINS AS POTENT AND SELECTIVE ACHE AND MAO-B DUAL INHIBITORS WITH A THERAPEUTIC POTENTIAL IN NEURODEGENERATIVE DISORDERS 1-gen-2013 Pisani, Leonardo; Catto, Marco; Stefanachi, Angela; Leonetti, F; Campagna, Francesco; Nicolotti, O; SOTO OTERO, R; Carotti, A.
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 1-gen-2013 Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A.
4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview) 1-gen-2018 Rullo, Mariagrazia; Pisani, Leonardo
5-aroyl-3,4-dihydropyrimidin-2-one library generation via automated sequential and parallel microwave-assisted synthesis techniques 1-gen-2007 Pisani, Leonardo; Prokopcová, Hana; Kremsner, Jennifer M.; Oliver Kappe, C.
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 1-gen-2011 Barletta, M.; Pisani, Leonardo; Catto, Marco; Nicolotti, Orazio; Soto Otero, R.; Carotti, Angelo
8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease 1-gen-2016 Dominguez, J. L.; Fernandez-Nieto, F.; Brea, J. M.; Catto, M.; Paleo, M. R.; Porto, S.; Sardina, F. J.; Castro, M.; Pisani, L.; Carotti, A.; Soto-Otero, R.; Mendez-Alvarez, E.; Villaverde, M. C.; Sussman, F.
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics 1-gen-2024 Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 1-gen-2010 Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A.
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE) 1-gen-2022 Leuci, R.; Brunetti, L.; Laghezza, A.; Piemontese, L.; Carrieri, A.; Pisani, L.; Tortorella, P.; Catto, M.; Loiodice, F.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease 1-gen-2019 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
A rational approach to elucidate human monoamine oxidase molecular selectivity 1-gen-2017 Mangiatordi, Giuseppe Felice; Alberga, Domenico; Pisani, Leonardo; Gadaleta, Domenico; Trisciuzzi, Daniela; Farina, Roberta; Carotti, A; Lattanzi, G; Catto, Marco; Nicolotti, Orazio
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules 1-gen-2022 Pisani, Leonardo; Catto, Marco; Muncipinto, Giovanni; Nicolotti, Orazio; Carrieri, Antonio; Rullo, Mariagrazia; Stefanachi, Angela; Leonetti, Francesco; Altomare, Cosimo
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. 1-gen-2019 Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G.
Application of Liebeskind-Srogl Thioester-Boronic Acid Couplings for the Scaffold Decoration of Dihydropyrimidines 1-gen-2006 Pisani, L.; Prokopcová, H.; Kappe, C. O.
Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitors 1-gen-2018 Mangiatordi, G. F.; Trisciuzzi, D.; Iacobazzi, R.; Denora, N.; Pisani, L.; Catto, M.; Leonetti, F.; Alberga, D.; Nicolotti, O.
Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents 1-gen-2021 Titov, Alexander A; Kobzev, Maxim S; Catto, Marco; Candia, Modesto de; Gambacorta, Nicola; Denora, Nunzio; Pisani, Leonardo; Nicolotti, Orazio; Borisova, Tatiana N; Varlamov, Alexey V; Voskressensky, Leonid G; Altomare, Cosimo D