NICOLOTTI, ORAZIO
NICOLOTTI, ORAZIO
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK
2014-01-01 Cellamare, Saverio; Carotti, Angelo; Stefanachi, Angela; Leonetti, Francesco; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Tardia, Piero; Introcaso, Antonellina; Valentina, Leo; Addabbo, Francesco; Montagnani, Monica; Nacci, Carmela
(Hetero-)(arylidene)arylhydrazides as multitarget-directed monoamine oxidase inhibitors
2020-01-01 Palakkathondi, A.; Oh, J. M.; Dev, S.; Rangarajan, T. M.; Kaipakasseri, S.; Kavully, F. S.; Gambacorta, N.; Nicolotti, O.; Kim, H.; Mathew, B.
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships
2008-01-01 Stefanachi, Angela; Nicolotti, Orazio; Leonetti, Francesco; Cellamare, Saverio; Campagna, Francesco; Loza, Mi; Brea, Jm; Mazza, F; Gavuzzo, E; Carotti, Angelo
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships
2009-01-01 Fernandez, F; Caamano, O; Nieto, Mi; Lopez, C; Garcia Mera, X; Stefanachi, Angela; Nicolotti, Orazio; Loza, Mi; Brea, J; Esteve, C; Segarra, V; Vidal, B; Carotti, Angelo
17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer
2021-01-01 Gargano, E. M.; Mohamed, A.; Abdelsamie, A. S.; Mangiatordi, G. F.; Drzewiecka, H.; Jagodzinski, P. P.; Mazzini, A.; Van Koppen, C. J.; Laschke, M. W.; Nicolotti, O.; Carotti, A.; Marchais-Oberwinkler, S.; Hartmann, R. W.; Frotscher, M.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease.
2021-01-01 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders
2013-01-01 Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A.
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors
2011-01-01 Barletta, M.; Pisani, Leonardo; Catto, Marco; Nicolotti, Orazio; Soto Otero, R.; Carotti, Angelo
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B
2004-01-01 Carotti, Angelo; Stefanachi, Angela; Ravina, E; Sotelo, E; Loza, Mi; Cadavid, Mi; Centeno, Nb; Nicolotti, Orazio
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies
2004-01-01 Carotti, A; Cadavid, M. I.; Centeno, N. B.; Esteve, C; Fontaine, F; GUTIÉRREZ DE TERÁN, H; Loza, M. I.; Martinez, A; Nicolotti, Orazio; Nieto, R; Pastor, M; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Stefanachi, Angela
A chemocentric approach to the identification of cancer targets
2012-01-01 Flachner, B; Lorincz, Z; Carotti, Angelo; Nicolotti, Orazio; Kuchipudi, P; Remez, N; Sanz, F; Tovari, J; Szabo, Mj; Bertok, B; Cseh, S; Mestres, J; Dorman, G.
A comprehensive review of monoamine oxidase-a inhibitors in their syntheses and potencies
2020-01-01 Rehuman, N. A.; Mathew, B.; Jat, R. K.; Nicolotti, O.; Kim, H.
A generalizable definition of chemical similarity for read-across
2014-01-01 Floris, M; Manganaro, A; Nicolotti, Orazio; Medda, R; Mangiatordi, Gf; Benfenati, E.
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
2014-01-01 Gadaleta, Domenico; Pizzo, Fabiola; Lombardo, Anna; Carotti, Angelo; Escher, Sylvia E.; Nicolotti, Orazio; Benfenati, Emilio
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat
2014-01-01 Gadaleta, D.; Pizzo, F.; Lombardo, A.; Carotti, A.; Escher, S. E.; Nicolotti, O.; Benfenati, E.
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor.
2010-01-01 Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A.
A multi-objective approach to deriving QSAR models
2003-01-01 Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D.
A Multi-Objective Optimization Algorithm for Molecular Design
2009-01-01 Giangreco, I; Nicolotti, Orazio; Miscioscia, T. F.; Convertino, M; Mangiatordi, G. F.; Siragusa, L; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Carotti, A.
A multiobjective approach to deriving QSAR models
2004-01-01 Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D.
A multitarget approach in cancer research
2009-01-01 Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK | 1-gen-2014 | Cellamare, Saverio; Carotti, Angelo; Stefanachi, Angela; Leonetti, Francesco; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Tardia, Piero; Introcaso, Antonellina; Valentina, Leo; Addabbo, Francesco; Montagnani, Monica; Nacci, Carmela | |
(Hetero-)(arylidene)arylhydrazides as multitarget-directed monoamine oxidase inhibitors | 1-gen-2020 | Palakkathondi, A.; Oh, J. M.; Dev, S.; Rangarajan, T. M.; Kaipakasseri, S.; Kavully, F. S.; Gambacorta, N.; Nicolotti, O.; Kim, H.; Mathew, B. | |
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships | 1-gen-2008 | Stefanachi, Angela; Nicolotti, Orazio; Leonetti, Francesco; Cellamare, Saverio; Campagna, Francesco; Loza, Mi; Brea, Jm; Mazza, F; Gavuzzo, E; Carotti, Angelo | |
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships | 1-gen-2009 | Fernandez, F; Caamano, O; Nieto, Mi; Lopez, C; Garcia Mera, X; Stefanachi, Angela; Nicolotti, Orazio; Loza, Mi; Brea, J; Esteve, C; Segarra, V; Vidal, B; Carotti, Angelo | |
17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer | 1-gen-2021 | Gargano, E. M.; Mohamed, A.; Abdelsamie, A. S.; Mangiatordi, G. F.; Drzewiecka, H.; Jagodzinski, P. P.; Mazzini, A.; Van Koppen, C. J.; Laschke, M. W.; Nicolotti, O.; Carotti, A.; Marchais-Oberwinkler, S.; Hartmann, R. W.; Frotscher, M. | |
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. | 1-gen-2021 | Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D. | |
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders | 1-gen-2013 | Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A. | |
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors | 1-gen-2011 | Barletta, M.; Pisani, Leonardo; Catto, Marco; Nicolotti, Orazio; Soto Otero, R.; Carotti, Angelo | |
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B | 1-gen-2004 | Carotti, Angelo; Stefanachi, Angela; Ravina, E; Sotelo, E; Loza, Mi; Cadavid, Mi; Centeno, Nb; Nicolotti, Orazio | |
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies | 1-gen-2004 | Carotti, A; Cadavid, M. I.; Centeno, N. B.; Esteve, C; Fontaine, F; GUTIÉRREZ DE TERÁN, H; Loza, M. I.; Martinez, A; Nicolotti, Orazio; Nieto, R; Pastor, M; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Stefanachi, Angela | |
A chemocentric approach to the identification of cancer targets | 1-gen-2012 | Flachner, B; Lorincz, Z; Carotti, Angelo; Nicolotti, Orazio; Kuchipudi, P; Remez, N; Sanz, F; Tovari, J; Szabo, Mj; Bertok, B; Cseh, S; Mestres, J; Dorman, G. | |
A comprehensive review of monoamine oxidase-a inhibitors in their syntheses and potencies | 1-gen-2020 | Rehuman, N. A.; Mathew, B.; Jat, R. K.; Nicolotti, O.; Kim, H. | |
A generalizable definition of chemical similarity for read-across | 1-gen-2014 | Floris, M; Manganaro, A; Nicolotti, Orazio; Medda, R; Mangiatordi, Gf; Benfenati, E. | |
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat | 1-gen-2014 | Gadaleta, Domenico; Pizzo, Fabiola; Lombardo, Anna; Carotti, Angelo; Escher, Sylvia E.; Nicolotti, Orazio; Benfenati, Emilio | |
A k-NN algorithm for predicting oral sub-chronic toxicity in the rat | 1-gen-2014 | Gadaleta, D.; Pizzo, F.; Lombardo, A.; Carotti, A.; Escher, S. E.; Nicolotti, O.; Benfenati, E. | |
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. | 1-gen-2010 | Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A. | |
A multi-objective approach to deriving QSAR models | 1-gen-2003 | Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D. | |
A Multi-Objective Optimization Algorithm for Molecular Design | 1-gen-2009 | Giangreco, I; Nicolotti, Orazio; Miscioscia, T. F.; Convertino, M; Mangiatordi, G. F.; Siragusa, L; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Carotti, A. | |
A multiobjective approach to deriving QSAR models | 1-gen-2004 | Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D. | |
A multitarget approach in cancer research | 1-gen-2009 | Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A. |