IRIS

NICOLOTTI, ORAZIO

NICOLOTTI, ORAZIO  

DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO  

Risultati 1 - 20 di 193 (tempo di esecuzione: 0.034 secondi).
Titolo Data di pubblicazione Autore(i) File
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships 1-gen-2008 Stefanachi, Angela; Nicolotti, Orazio; Leonetti, Francesco; Cellamare, Saverio; Campagna, Francesco; Loza, Mi; Brea, Jm; Mazza, F; Gavuzzo, E; Carotti, Angelo
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships 1-gen-2009 Fernandez, F; Caamano, O; Nieto, Mi; Lopez, C; Garcia Mera, X; Stefanachi, Angela; Nicolotti, Orazio; Loza, Mi; Brea, J; Esteve, C; Segarra, V; Vidal, B; Carotti, Angelo
17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer 1-gen-2021 Gargano, E. M.; Mohamed, A.; Abdelsamie, A. S.; Mangiatordi, G. F.; Drzewiecka, H.; Jagodzinski, P. P.; Mazzini, A.; Van Koppen, C. J.; Laschke, M. W.; Nicolotti, O.; Carotti, A.; Marchais-Oberwinkler, S.; Hartmann, R. W.; Frotscher, M.
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 1-gen-2013 Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A.
6-Substituted-(E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides as novel, potent and selective MAO inhibitors 1-gen-2011 Barletta, M.; Pisani, Leonardo; Catto, Marco; Nicolotti, Orazio; Soto Otero, R.; Carotti, Angelo
8-Substituted- 9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B 1-gen-2004 Carotti, Angelo; Stefanachi, Angela; Ravina, E; Sotelo, E; Loza, Mi; Cadavid, Mi; Centeno, Nb; Nicolotti, Orazio
9-Deazaxanthines as selective A2B AR ligands: Design, Synthesis and SAFIR studies 1-gen-2004 Carotti, A; CADAVID M., I; CENTENO N., B; Esteve, C; Fontaine, F; GUTIÉRREZ DE TERÁN, H; LOZA M., I; Martinez, A; Nicolotti, Orazio; Nieto, R; Pastor, M; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Stefanachi, Angela
A molecular dynamics study of a sub-nanomolar dual binding site heterodimeric AChE inhibitor. 1-gen-2010 Nicolotti, Orazio; Giangreco, I; Pisani, Leonardo; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Cellamare, Saverio; Carotti, A.
A multi-objective approach to deriving QSAR models 1-gen-2003 Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D.
A Multi-Objective Optimization Algorithm for Molecular Design 1-gen-2009 Giangreco, I; Nicolotti, Orazio; Miscioscia T., F; Convertino, M; Mangiatordi G., F; Siragusa, L; Catto, Marco; Leonetti, Francesco; Stefanachi, Angela; Carotti, A.
A multiobjective approach to deriving QSAR models 1-gen-2004 Nicolotti, Orazio; Gillet, Vj; Fleming, P; Green, D.
A multitarget approach in cancer research 1-gen-2009 Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A.
A multitarget approach in cancer research. Joint Meeting on Medicinal Chemistry 1-gen-2009 Leonetti, Francesco; Stefanachi, Angela; Pellegrino, G; Nicolotti, Orazio; Catto, Marco; Muncipinto, G; Carotti, A.
A new approach to combine ligand- and structure-based drug design. 1-gen-2008 Nicolotti, Orazio; Miscioscia, Tf; Carotti, A; Leonetti, Francesco; Giangreco, I; Carotti, A.
A novel function for non-deterministic scouting of optimal QSAR models out of a highly-structured physicochemical space. 1-gen-2006 Nicolotti, Orazio; Miscioscia T., F; Leonetti, Francesco; Carotti, A.
Accelerating drug discovery by early protein drug target prediction based on a multi-fingerprint similarity search † 1-gen-2019 Montaruli, M.; Alberga, D.; Ciriaco, F.; Trisciuzzi, D.; Tondo, A. R.; Mangiatordi, G. F.; Nicolotti, O.
Activation of Rho Family GTPases by Small Molecules 1-gen-2018 Palsuledesai, Charuta C.; Surviladze, Zurab; Waller, Anna; Miscioscia, T. Fabiola; Guo, Yuna; Wu, Yang; Strouse, Jake; Romero, Elsa; Salas, Virginia M.; Curpan, Ramona; Young, Susan; Carter, Mark; Foutz, Terry; Galochkina, Zhanna; Ames, Harold; Haynes, Mark K.; Edwards, Bruce S.; Nicolotti, Orazio; Luo, Li; Ursu, Oleg; Bologa, Cristian G.; Oprea, Tudor I.; Wandinger-Ness, Angela; Sklar, Larry A.
Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde? 1-gen-2014 Cruz Monteagudo, M; Medina Franco, Jl; Pérez Castillo, Y; Nicolotti, Orazio; Cordeiro, Mnds; Borges, F.
Aldoxime- and hydroxy-functionalized chalcones as highly potent and selective monoamine oxidase-B inhibitors 1-gen-2022 Oh, J. M.; Rangarajan, T. M.; Chaudhary, R.; Gambacorta, N.; Nicolotti, O.; Kumar, S.; Mathew, B.; Kim, H.
Alloxan Derivatives as Inhibitors of Matrix Metalloproteinase-2: Theoretical Calculations and Experimental Results 1-gen-2010 Lattanzi, Gianluca; Ilenia, Giangreco; Nicolotti, Orazio; Catto, Marco; Angelo, Carotti