ALTOMARE, Cosimo Damiano
ALTOMARE, Cosimo Damiano
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
). A simple Synthesis of Heterocyclic Ring System Containing the 1,3-oxazine Nucleus
1984-01-01 Altomare, Cosimo Damiano; Carotti, A; Casini, G; Ferappi, M.
1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1
2019-01-01 Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano
2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity
2012-01-01 Soto Otero, R; Mendez Alvarez, E; Sanchez Iglesias, S; Labandeira Garcıa, Jl; Rodrıguez Pallares, J; Zubkov, Fi; Zaytsev, Vp; Voskressensky, Lg; Varlamov, Av; DE CANDIA, Modesto; Fiorella, F; Altomare, Cosimo Damiano
2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line.
2015-01-01 Midzak, A; Denora, Nunzio; Laquintana, Valentino; Cutrignelli, Annalisa; Lopedota, Angela Assunta; Franco, Massimo; Altomare, Cosimo Damiano; Papadopoulos, V.
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance
2019-01-01 Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease.
2021-01-01 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
3D-QSAR models and docking studies of reversible inhibitors of type A and B Monoamine Oxidases
2001-01-01 Carotti, A.; Barreca, M. L.; PELLEGRINI CALACE, M.; Carrieri, Antonio; Altomare, Cosimo Damiano
6-to-8 and 7-to-9 membered ring expansion in annulated tetrahydropyridines and azepines – novel approach toward azocine and azonine derivatives with substantial bioactivity
2005-01-01 Voskressensky, L. G.; Borisova, T. N.; Altomare, Cosimo Damiano; Kulikova, L. N.; Varlamov, A. V.
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics
2024-01-01 Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano
A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles
2017-01-01 Parisi, Giovanna; Degennaro, Leonardo; Carlucci, Claudia; DE CANDIA, Modesto; Mastrorilli, Pietro; Roller, A; Holzer, W; Altomare, Cosimo Damiano; Pace, V; Luisi, Renzo
A natural prothrombin mutant reveals an unexpected influence of the A-chain’s structure on the activity of human alpha-thrombin
2004-01-01 DE CRISTOFARO, R.; Akhavan, S.; Altomare, Cosimo Damiano; Carotti, Angelo; Peyvandi, F.; Mannucci, P. M.
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells
2018-01-01 Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease
2019-01-01 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
A second life for MAO inhibitors? From CNS diseases to anticancer therapy
2024-01-01 Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus
1984-01-01 Altomare, Cosimo Damiano; Carotti, Angelo; Casini, G.; Ferappi, M.
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules
2022-01-01 Pisani, Leonardo; Catto, Marco; Muncipinto, Giovanni; Nicolotti, Orazio; Carrieri, Antonio; Rullo, Mariagrazia; Stefanachi, Angela; Leonetti, Francesco; Altomare, Cosimo
Advanced methodologies in medicinal chemistry research
1995-01-01 Carotti, Angelo; Altomare, Cosimo Damiano
Advances in synthesis of novel annulated azecines and their unique pharmacological properties
2024-01-01 Listratova, Anna V.; Samarelli, Francesco; Titov, Alexander A.; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Varlamov, Alexey V.; Voskressensky, Leonid G.; Altomare, Cosimo D.
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines
1993-01-01 Carotti, Angelo; Carta, V.; Campagna, F.; Altomare, Cosimo Damiano; Casini, G.
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads.
2019-01-01 Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
). A simple Synthesis of Heterocyclic Ring System Containing the 1,3-oxazine Nucleus | 1-gen-1984 | Altomare, Cosimo Damiano; Carotti, A; Casini, G; Ferappi, M. | |
1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1 | 1-gen-2019 | Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano | |
2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity | 1-gen-2012 | Soto Otero, R; Mendez Alvarez, E; Sanchez Iglesias, S; Labandeira Garcıa, Jl; Rodrıguez Pallares, J; Zubkov, Fi; Zaytsev, Vp; Voskressensky, Lg; Varlamov, Av; DE CANDIA, Modesto; Fiorella, F; Altomare, Cosimo Damiano | |
2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line. | 1-gen-2015 | Midzak, A; Denora, Nunzio; Laquintana, Valentino; Cutrignelli, Annalisa; Lopedota, Angela Assunta; Franco, Massimo; Altomare, Cosimo Damiano; Papadopoulos, V. | |
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance | 1-gen-2019 | Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D. | |
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. | 1-gen-2021 | Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D. | |
3D-QSAR models and docking studies of reversible inhibitors of type A and B Monoamine Oxidases | 1-gen-2001 | Carotti, A.; Barreca, M. L.; PELLEGRINI CALACE, M.; Carrieri, Antonio; Altomare, Cosimo Damiano | |
6-to-8 and 7-to-9 membered ring expansion in annulated tetrahydropyridines and azepines – novel approach toward azocine and azonine derivatives with substantial bioactivity | 1-gen-2005 | Voskressensky, L. G.; Borisova, T. N.; Altomare, Cosimo Damiano; Kulikova, L. N.; Varlamov, A. V. | |
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics | 1-gen-2024 | Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano | |
A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles | 1-gen-2017 | Parisi, Giovanna; Degennaro, Leonardo; Carlucci, Claudia; DE CANDIA, Modesto; Mastrorilli, Pietro; Roller, A; Holzer, W; Altomare, Cosimo Damiano; Pace, V; Luisi, Renzo | |
A natural prothrombin mutant reveals an unexpected influence of the A-chain’s structure on the activity of human alpha-thrombin | 1-gen-2004 | DE CRISTOFARO, R.; Akhavan, S.; Altomare, Cosimo Damiano; Carotti, Angelo; Peyvandi, F.; Mannucci, P. M. | |
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells | 1-gen-2018 | Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G. | |
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease | 1-gen-2019 | Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M | |
A second life for MAO inhibitors? From CNS diseases to anticancer therapy | 1-gen-2024 | Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D. | |
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus | 1-gen-1984 | Altomare, Cosimo Damiano; Carotti, Angelo; Casini, G.; Ferappi, M. | |
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules | 1-gen-2022 | Pisani, Leonardo; Catto, Marco; Muncipinto, Giovanni; Nicolotti, Orazio; Carrieri, Antonio; Rullo, Mariagrazia; Stefanachi, Angela; Leonetti, Francesco; Altomare, Cosimo | |
Advanced methodologies in medicinal chemistry research | 1-gen-1995 | Carotti, Angelo; Altomare, Cosimo Damiano | |
Advances in synthesis of novel annulated azecines and their unique pharmacological properties | 1-gen-2024 | Listratova, Anna V.; Samarelli, Francesco; Titov, Alexander A.; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Varlamov, Alexey V.; Voskressensky, Leonid G.; Altomare, Cosimo D. | |
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines | 1-gen-1993 | Carotti, Angelo; Carta, V.; Campagna, F.; Altomare, Cosimo Damiano; Casini, G. | |
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. | 1-gen-2019 | Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G. |