ALTOMARE, Cosimo Damiano

ALTOMARE, Cosimo Damiano  

DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO  

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). A simple Synthesis of Heterocyclic Ring System Containing the 1,3-oxazine Nucleus 1-gen-1984 Altomare, Cosimo Damiano; Carotti, A; Casini, G; Ferappi, M.
1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1 1-gen-2019 Rullo, Mariagrazia; Niso, Mauro; Pisani, Leonardo; Carrieri, Antonio; Colabufo, Nicola Antonio; Cellamare, Saverio; Altomare, Cosimo Damiano
2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity 1-gen-2012 Soto Otero, R; Mendez Alvarez, E; Sanchez Iglesias, S; Labandeira Garcıa, Jl; Rodrıguez Pallares, J; Zubkov, Fi; Zaytsev, Vp; Voskressensky, Lg; Varlamov, Av; DE CANDIA, Modesto; Fiorella, F; Altomare, Cosimo Damiano
2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line. 1-gen-2015 Midzak, A; Denora, Nunzio; Laquintana, Valentino; Cutrignelli, Annalisa; Lopedota, Angela Assunta; Franco, Massimo; Altomare, Cosimo Damiano; Papadopoulos, V.
3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance 1-gen-2019 Titov, A. A.; Niso, M.; Candia, M.; Kobzev, M. S.; Varlamov, A. V.; Borisova, T. N.; Voskressensky, L. G.; Colabufo, N. A.; Cellamare, S.; Pisani, L.; Altomare, C. D.
3D-QSAR and pharmacophore mapping of 1H-indole-2,3-dione adducts inhibiting beta-amyloid aggregation and other major targets related to Alzheimer’s Disease. 1-gen-2021 Purgatorio, R.; Gambacorta, N.; Catto, M.; de Candia, M.; Pisani, L.; Rullo, M.; Nicolotti, O.; Altomare, C. D.
3D-QSAR models and docking studies of reversible inhibitors of type A and B Monoamine Oxidases 1-gen-2001 Carotti, A.; Barreca, M. L.; PELLEGRINI CALACE, M.; Carrieri, Antonio; Altomare, Cosimo Damiano
6-to-8 and 7-to-9 membered ring expansion in annulated tetrahydropyridines and azepines – novel approach toward azocine and azonine derivatives with substantial bioactivity 1-gen-2005 Voskressensky, L. G.; Borisova, T. N.; Altomare, Cosimo Damiano; Kulikova, L. N.; Varlamov, A. V.
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics 1-gen-2024 Purgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo Damiano
A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles 1-gen-2017 Parisi, Giovanna; Degennaro, Leonardo; Carlucci, Claudia; DE CANDIA, Modesto; Mastrorilli, Pietro; Roller, A; Holzer, W; Altomare, Cosimo Damiano; Pace, V; Luisi, Renzo
A natural prothrombin mutant reveals an unexpected influence of the A-chain’s structure on the activity of human alpha-thrombin 1-gen-2004 DE CRISTOFARO, R.; Akhavan, S.; Altomare, Cosimo Damiano; Carotti, Angelo; Peyvandi, F.; Mannucci, P. M.
A new class of 1-aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline derivatives as reversers of P-glycoprotein-mediated multidrug resistance in tumor cells 1-gen-2018 Altomare, Cosimo Damiano; Nevskaya, Alisa A.; Matveeva, Maria D.; Borisova, Tatiana N.; Niso, Mauro; Colabufo, Nicola Antonio; Boccarelli, Angelina; Purgatorio, Rosa; de Candia, Modesto; Cellamare, Saverio; Voskressensky, Leonid G.
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease 1-gen-2019 Bolognino, I; Giangregorio, N; Pisani, L; de Candia, M; Purgatorio, R; Tonazzi, A; Altomare, Cd; Cellamare, S; Catto, M
A second life for MAO inhibitors? From CNS diseases to anticancer therapy 1-gen-2024 Sblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; DE CANDIA, Modesto; Catto, Marco; Altomare, Cosimo D.
A simple Synthesis of Heterocyclic Ring Systems Containing the 1,3-oxazine Nucleus 1-gen-1984 Altomare, Cosimo Damiano; Carotti, Angelo; Casini, G.; Ferappi, M.
A twenty-year journey exploring coumarin-based derivatives as bioactive molecules 1-gen-2022 Pisani, Leonardo; Catto, Marco; Muncipinto, Giovanni; Nicolotti, Orazio; Carrieri, Antonio; Rullo, Mariagrazia; Stefanachi, Angela; Leonetti, Francesco; Altomare, Cosimo
Advanced methodologies in medicinal chemistry research 1-gen-1995 Carotti, Angelo; Altomare, Cosimo Damiano
An efficient Route to Biologically Active 5H-Indeno[1,2-c]Pyridazines 1-gen-1993 Carotti, Angelo; Carta, V.; Campagna, F.; Altomare, Cosimo Damiano; Casini, G.
Annelated medium-sized azaheterocycles as attractive scaffolds for CNS targeted leads. 1-gen-2019 Altomare, C. D.; de Candia, M.; Purgatorio, R.; Pisani, L.; Catto, M.; Cellamare, S.; Titov, A. A.; Voskressensky, L. G.
Anticancer potential of novel α,β-unsaturated γ-lactam derivatives targeting the PI3K/AKT signaling pathway 1-gen-2021 Brindisi, Matteo; Frattaruolo, Luca; Mancuso, Raffaella; Palumbo Piccionello, Antonio; Ziccarelli, Ida; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D; Gabriele, Bartolo; Rita Cappello, Anna