ABATE, CARMEN
ABATE, CARMEN
DIPARTIMENTO DI FARMACIA-SCIENZE DEL FARMACO
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco
1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review
2009-01-01 Berardi, Francesco; Abate, CARMEN rosa; Ferorelli, Savina; Colabufo, Nicola Antonio; Perrone, Roberto
2-Aminopyridine derivatives as potential sigma2 receptor antagonists
2012-01-01 Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity
2004-01-01 Berardi, Francesco; Ferorelli, Savina; Abate, CARMEN rosa; Colabufo, N. C.; Contino, Marialessandra; Perrone, Roberto; Tortorella, V.
A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach
2023-01-01 Abatematteo, Francesca Serena; Delre, Pietro; Mercurio, Ivan; Rezelj, Veronica V; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo, Nicola Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, Giuseppe Felice; Abate, Carmen
A Structure-Affinity and Comparative Molecular Field Analysis of Sigma-2 (σ2) Receptor Ligands
2009-01-01 Abate, CARMEN rosa; PHILIP DANIEL, Mosier; Berardi, Francesco; RICHARD A., Glennon
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis
2023-01-01 Lomuscio, Maria Cristina; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo, Nicola Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, Giuseppe Felice
Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto
Antiproliferative and cytotoxic effects of some sigma-2 agonists and sigma-1 antagonists in tumour cell lines
2004-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Niso, Mauro; Abate, CARMEN rosa; Perrone, Roberto; Tortorella, V.
Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers
2011-01-01 Abate, CARMEN rosa; Ferorelli, Savina; Contino, Marialessandra; Marottoli, R; Colabufo, Nicola Antonio; Perrone, Roberto; Berardi, Francesco
Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration
2020-01-01 Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra
Cannabinoid receptor subtype 2 (CB2R): Features and targets for medical applications
2023-01-01 Contino, M; Abate, C; Colabufo, Na; Leonetti, F; Stefanachi, A
Classes of sigma2 ( o-2) receptor ligands: structure affinity relationship (SAfiR) studies and antiproliferative activity
2012-01-01 Abate, CARMEN rosa; Perrone, R; Berardi, Francesco
Collateral Sensitivity of sigma2 Receptor ligands: Potentials in the Treatment of Multidrug Resistant Tumors
2014-01-01 Niso, Mauro; Chiara, Riganti; Abate, CARMEN rosa
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
2020-01-01 Gordon, David E; Hiatt, Joseph; Bouhaddou, Mehdi; Rezelj, Veronica V; Ulferts, Svenja; Braberg, Hannes; Jureka, Alexander S; Obernier, Kirsten; Guo, Jeffrey Z; Batra, Jyoti; Kaake, Robyn M; Weckstein, Andrew R; Owens, Tristan W; Gupta, Meghna; Pourmal, Sergei; Titus, Erron W; Cakir, Merve; Soucheray, Margaret; Mcgregor, Michael; Cakir, Zeynep; Jang, Gwendolyn; O'Meara, Matthew J; Tummino, Tia A; Zhang, Ziyang; Foussard, Helene; Rojc, Ajda; Zhou, Yuan; Kuchenov, Dmitry; Hüttenhain, Ruth; Xu, Jiewei; Eckhardt, Manon; Swaney, Danielle L; Fabius, Jacqueline M; Ummadi, Manisha; Tutuncuoglu, Beril; Rathore, Ujjwal; Modak, Maya; Haas, Paige; Haas, Kelsey M; Naing, Zun Zar Chi; Pulido, Ernst H; Shi, Ying; Barrio-Hernandez, Inigo; Memon, Danish; Petsalaki, Eirini; Dunham, Alistair; Marrero, Miguel Correa; Burke, David; Koh, Cassandra; Vallet, Thomas; Silvas, Jesus A; Azumaya, Caleigh M; Billesbølle, Christian; Brilot, Axel F; Campbell, Melody G; Diallo, Amy; Dickinson, Miles Sasha; Diwanji, Devan; Herrera, Nadia; Hoppe, Nick; Kratochvil, Huong T; Liu, Yanxin; Merz, Gregory E; Moritz, Michelle; Nguyen, Henry C; Nowotny, Carlos; Puchades, Cristina; Rizo, Alexandrea N; Schulze-Gahmen, Ursula; Smith, Amber M; Sun, Ming; Young, Iris D; Zhao, Jianhua; Asarnow, Daniel; Biel, Justin; Bowen, Alisa; Braxton, Julian R; Chen, Jen; Chio, Cynthia M; Chio, Un Seng; Deshpande, Ishan; Doan, Loan; Faust, Bryan; Flores, Sebastian; Jin, Mingliang; Kim, Kate; Lam, Victor L; Li, Fei; Li, Junrui; Li, Yen-Li; Li, Yang; Liu, Xi; Lo, Megan; Lopez, Kyle E; Melo, Arthur A; Moss, Frank R; Nguyen, Phuong; Paulino, Joana; Pawar, Komal Ishwar; Peters, Jessica K; Pospiech, Thomas H; Safari, Maliheh; Sangwan, Smriti; Schaefer, Kaitlin; Thomas, Paul V; Thwin, Aye C; Trenker, Raphael; Tse, Eric; Tsui, Tsz Kin Martin; Wang, Feng; Whitis, Natalie; Yu, Zanlin; Zhang, Kaihua; Zhang, Yang; Zhou, Fengbo; Saltzberg, Daniel; Hodder, Anthony J; Shun-Shion, Amber S; Williams, Daniel M; White, Kris M; Rosales, Romel; Kehrer, Thomas; Miorin, Lisa; Moreno, Elena; Patel, Arvind H; Rihn, Suzannah; Khalid, Mir M; Vallejo-Gracia, Albert; Fozouni, Parinaz; Simoneau, Camille R; Roth, Theodore L; Wu, David; Karim, Mohd Anisul; Ghoussaini, Maya; Dunham, Ian; Berardi, Francesco; Weigang, Sebastian; Chazal, Maxime; Park, Jisoo; Logue, James; Mcgrath, Marisa; Weston, Stuart; Haupt, Robert; Hastie, C James; Elliott, Matthew; Brown, Fiona; Burness, Kerry A; Reid, Elaine; Dorward, Mark; Johnson, Clare; Wilkinson, Stuart G; Geyer, Anna; Giesel, Daniel M; Baillie, Carla; Raggett, Samantha; Leech, Hannah; Toth, Rachel; Goodman, Nicola; Keough, Kathleen C; Lind, Abigail L; Klesh, Reyna J; Hemphill, Kafi R; Carlson-Stevermer, Jared; Oki, Jennifer; Holden, Kevin; Maures, Travis; Pollard, Katherine S; Sali, Andrej; Agard, David A; Cheng, Yifan; Fraser, James S; Frost, Adam; Jura, Natalia; Kortemme, Tanja; Manglik, Aashish; Southworth, Daniel R; Stroud, Robert M; Alessi, Dario R; Davies, Paul; Frieman, Matthew B; Ideker, Trey; Abate, Carmen; Jouvenet, Nolwenn; Kochs, Georg; Shoichet, Brian; Ott, Melanie; Palmarini, Massimo; Shokat, Kevan M; García-Sastre, Adolfo; Rassen, Jeremy A; Grosse, Robert; Rosenberg, Oren S; Verba, Kliment A; Basler, Christopher F; Vignuzzi, Marco; Peden, Andrew A; Beltrao, Pedro; Krogan, Nevan J
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells
2023-01-01 Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents
2015-01-01 Pati, MARIA LAURA; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Luisi, Renzo; Laura, Carroccia; Niso, Mauro; Berardi, Francesco
Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies
2007-01-01 Ferorelli, Savina; Abate, CARMEN rosa; Colabufo, An; Niso, Mauro; Inglese, C; Berardi, Francesco; Perrone, Roberto
Design and Synthesis of Arylpiperazine Serotonergic/ Dopaminergic Ligands with Neuroprotective Properties
2022-01-01 Mastromarino, M.; Niso, M.; Abate, C.; Proschak, E.; Dubiel, M.; Stark, H.; Castro, M.; Lacivita, E.; Leopoldo, M.
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R)
2020-01-01 Spinelli, F.; Giampietro, R.; Stefanachi, A.; Riganti, C.; Kopecka, J.; Abatematteo, F. S.; Leonetti, F.; Colabufo, N. A.; Mangiatordi, G. F.; Nicolotti, O.; Perrone, M. G.; Brea, J.; Loza, M. I.; Infantino, V.; Abate, C.; Contino, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco | |
| 1-Cyclohexylpiperazine and 3,3-Dimethylpiperidine Derivatives as Sigma-1 (σ1) and Sigma-2 (σ2) Receptor Ligands: A Review | 1-gen-2009 | Berardi, Francesco; Abate, CARMEN rosa; Ferorelli, Savina; Colabufo, Nicola Antonio; Perrone, Roberto | |
| 2-Aminopyridine derivatives as potential sigma2 receptor antagonists | 1-gen-2012 | Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco | |
| 4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cycloheylpiperazine as sigma receptor Ligands with Agonist sigma 2 Activity | 1-gen-2004 | Berardi, Francesco; Ferorelli, Savina; Abate, CARMEN rosa; Colabufo, N. C.; Contino, Marialessandra; Perrone, Roberto; Tortorella, V. | |
| A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach | 1-gen-2023 | Abatematteo, Francesca Serena; Delre, Pietro; Mercurio, Ivan; Rezelj, Veronica V; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo, Nicola Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, Giuseppe Felice; Abate, Carmen | |
| A Structure-Affinity and Comparative Molecular Field Analysis of Sigma-2 (σ2) Receptor Ligands | 1-gen-2009 | Abate, CARMEN rosa; PHILIP DANIEL, Mosier; Berardi, Francesco; RICHARD A., Glennon | |
| AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis | 1-gen-2023 | Lomuscio, Maria Cristina; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo, Nicola Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, Giuseppe Felice | |
| Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto | |
| Antiproliferative and cytotoxic effects of some sigma-2 agonists and sigma-1 antagonists in tumour cell lines | 1-gen-2004 | Colabufo, Nicola Antonio; Berardi, Francesco; Contino, Marialessandra; Niso, Mauro; Abate, CARMEN rosa; Perrone, Roberto; Tortorella, V. | |
| Arylamides hybrids of two high-affinity sigma-2 receptor ligands as tools for the development of PET radiotracers | 1-gen-2011 | Abate, CARMEN rosa; Ferorelli, Savina; Contino, Marialessandra; Marottoli, R; Colabufo, Nicola Antonio; Perrone, Roberto; Berardi, Francesco | |
| Cannabinoid Receptor Subtype 2 (CB2R) in a Multitarget Approach: Perspective of an Innovative Strategy in Cancer and Neurodegeneration | 1-gen-2020 | Mangiatordi, Giuseppe Felice; Intranuovo, Francesca; Delre, Pietro; Abatematteo, Francesca Serena; Abate, Carmen; Niso, Mauro; Creanza, Teresa Maria; Ancona, Nicola; Stefanachi, Angela; Contino, Marialessandra | |
| Cannabinoid receptor subtype 2 (CB2R): Features and targets for medical applications | 1-gen-2023 | Contino, M; Abate, C; Colabufo, Na; Leonetti, F; Stefanachi, A | |
| Classes of sigma2 ( o-2) receptor ligands: structure affinity relationship (SAfiR) studies and antiproliferative activity | 1-gen-2012 | Abate, CARMEN rosa; Perrone, R; Berardi, Francesco | |
| Collateral Sensitivity of sigma2 Receptor ligands: Potentials in the Treatment of Multidrug Resistant Tumors | 1-gen-2014 | Niso, Mauro; Chiara, Riganti; Abate, CARMEN rosa | |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms | 1-gen-2020 | Gordon, David E; Hiatt, Joseph; Bouhaddou, Mehdi; Rezelj, Veronica V; Ulferts, Svenja; Braberg, Hannes; Jureka, Alexander S; Obernier, Kirsten; Guo, Jeffrey Z; Batra, Jyoti; Kaake, Robyn M; Weckstein, Andrew R; Owens, Tristan W; Gupta, Meghna; Pourmal, Sergei; Titus, Erron W; Cakir, Merve; Soucheray, Margaret; Mcgregor, Michael; Cakir, Zeynep; Jang, Gwendolyn; O'Meara, Matthew J; Tummino, Tia A; Zhang, Ziyang; Foussard, Helene; Rojc, Ajda; Zhou, Yuan; Kuchenov, Dmitry; Hüttenhain, Ruth; Xu, Jiewei; Eckhardt, Manon; Swaney, Danielle L; Fabius, Jacqueline M; Ummadi, Manisha; Tutuncuoglu, Beril; Rathore, Ujjwal; Modak, Maya; Haas, Paige; Haas, Kelsey M; Naing, Zun Zar Chi; Pulido, Ernst H; Shi, Ying; Barrio-Hernandez, Inigo; Memon, Danish; Petsalaki, Eirini; Dunham, Alistair; Marrero, Miguel Correa; Burke, David; Koh, Cassandra; Vallet, Thomas; Silvas, Jesus A; Azumaya, Caleigh M; Billesbølle, Christian; Brilot, Axel F; Campbell, Melody G; Diallo, Amy; Dickinson, Miles Sasha; Diwanji, Devan; Herrera, Nadia; Hoppe, Nick; Kratochvil, Huong T; Liu, Yanxin; Merz, Gregory E; Moritz, Michelle; Nguyen, Henry C; Nowotny, Carlos; Puchades, Cristina; Rizo, Alexandrea N; Schulze-Gahmen, Ursula; Smith, Amber M; Sun, Ming; Young, Iris D; Zhao, Jianhua; Asarnow, Daniel; Biel, Justin; Bowen, Alisa; Braxton, Julian R; Chen, Jen; Chio, Cynthia M; Chio, Un Seng; Deshpande, Ishan; Doan, Loan; Faust, Bryan; Flores, Sebastian; Jin, Mingliang; Kim, Kate; Lam, Victor L; Li, Fei; Li, Junrui; Li, Yen-Li; Li, Yang; Liu, Xi; Lo, Megan; Lopez, Kyle E; Melo, Arthur A; Moss, Frank R; Nguyen, Phuong; Paulino, Joana; Pawar, Komal Ishwar; Peters, Jessica K; Pospiech, Thomas H; Safari, Maliheh; Sangwan, Smriti; Schaefer, Kaitlin; Thomas, Paul V; Thwin, Aye C; Trenker, Raphael; Tse, Eric; Tsui, Tsz Kin Martin; Wang, Feng; Whitis, Natalie; Yu, Zanlin; Zhang, Kaihua; Zhang, Yang; Zhou, Fengbo; Saltzberg, Daniel; Hodder, Anthony J; Shun-Shion, Amber S; Williams, Daniel M; White, Kris M; Rosales, Romel; Kehrer, Thomas; Miorin, Lisa; Moreno, Elena; Patel, Arvind H; Rihn, Suzannah; Khalid, Mir M; Vallejo-Gracia, Albert; Fozouni, Parinaz; Simoneau, Camille R; Roth, Theodore L; Wu, David; Karim, Mohd Anisul; Ghoussaini, Maya; Dunham, Ian; Berardi, Francesco; Weigang, Sebastian; Chazal, Maxime; Park, Jisoo; Logue, James; Mcgrath, Marisa; Weston, Stuart; Haupt, Robert; Hastie, C James; Elliott, Matthew; Brown, Fiona; Burness, Kerry A; Reid, Elaine; Dorward, Mark; Johnson, Clare; Wilkinson, Stuart G; Geyer, Anna; Giesel, Daniel M; Baillie, Carla; Raggett, Samantha; Leech, Hannah; Toth, Rachel; Goodman, Nicola; Keough, Kathleen C; Lind, Abigail L; Klesh, Reyna J; Hemphill, Kafi R; Carlson-Stevermer, Jared; Oki, Jennifer; Holden, Kevin; Maures, Travis; Pollard, Katherine S; Sali, Andrej; Agard, David A; Cheng, Yifan; Fraser, James S; Frost, Adam; Jura, Natalia; Kortemme, Tanja; Manglik, Aashish; Southworth, Daniel R; Stroud, Robert M; Alessi, Dario R; Davies, Paul; Frieman, Matthew B; Ideker, Trey; Abate, Carmen; Jouvenet, Nolwenn; Kochs, Georg; Shoichet, Brian; Ott, Melanie; Palmarini, Massimo; Shokat, Kevan M; García-Sastre, Adolfo; Rassen, Jeremy A; Grosse, Robert; Rosenberg, Oren S; Verba, Kliment A; Basler, Christopher F; Vignuzzi, Marco; Peden, Andrew A; Beltrao, Pedro; Krogan, Nevan J | |
| Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells | 1-gen-2023 | Kopecka, Joanna; Barbanente, Alessandra; Vitone, Daniele; Arnesano, Fabio; Margiotta, Nicola; Berchialla, Paola; Niso, Mauro; Riganti, Chiara; Abate, Carmen | |
| Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate Pglycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents | 1-gen-2015 | Pati, MARIA LAURA; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Luisi, Renzo; Laura, Carroccia; Niso, Mauro; Berardi, Francesco | |
| Design and evaluation of naphthol- and carbazole- containing fluorescent sigma ligands as potential probes for receptor binding studies | 1-gen-2007 | Ferorelli, Savina; Abate, CARMEN rosa; Colabufo, An; Niso, Mauro; Inglese, C; Berardi, Francesco; Perrone, Roberto | |
| Design and Synthesis of Arylpiperazine Serotonergic/ Dopaminergic Ligands with Neuroprotective Properties | 1-gen-2022 | Mastromarino, M.; Niso, M.; Abate, C.; Proschak, E.; Dubiel, M.; Stark, H.; Castro, M.; Lacivita, E.; Leopoldo, M. | |
| Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R) | 1-gen-2020 | Spinelli, F.; Giampietro, R.; Stefanachi, A.; Riganti, C.; Kopecka, J.; Abatematteo, F. S.; Leonetti, F.; Colabufo, N. A.; Mangiatordi, G. F.; Nicolotti, O.; Perrone, M. G.; Brea, J.; Loza, M. I.; Infantino, V.; Abate, C.; Contino, M. |